Xiaobo Zhang, Xiao Zhang, Xiaoyi Ding, Zhongmin Wang, Yong Fan, Guang Chen, Xiaokun Hu, Jiasheng Zheng, Zhixiao Xue, Xiaofeng He, Xin Zhang, Yingtian Wei, Zhongliang Zhang, Jing Li, Jie Li, Jie Yang, Xiaodong Xue, Li Ma, Yueyong Xiao
Irreversible electroporation (IRE) is a soft tissue ablation technique that uses short electrical fields which induce the death of target cells. To evaluate the safety and efficacy of an IRE-based device compared to regular radiofrequency ablation (RFA) of solid liver tumors, in this multicenter, randomized, parallel-arm, non-inferiority study, 152 patients with malignant liver tumors were randomized into IRE (n = 78) and RFA (n = 74) groups. The primary endpoint was the success rate of tumor ablation; the secondary endpoints included the tumor ablation time, complications, tumor recurrence rates and treatment-related adverse events (TRAE)...
2022: Frontiers in Oncology