Martha Resendiz-Hernández, Alejandra P García-Hernández, Macrina B Silva-Cázares, Rogelio Coronado-Uribe, Olga N Hernández-de la Cruz, Lourdes A Arriaga-Pizano, Jessica L Prieto-Chávez, Yarely M Salinas-Vera, Eloisa Ibarra-Sierra, Concepción Ortiz-Martínez, César López-Camarillo
Tumors have high requirements in terms of nutrients and oxygen. Angiogenesis is the classical mechanism for vessel formation. Tumoral vascularization has the function of nourishing the cancer cells to support tumor growth. Vasculogenic mimicry, a novel intratumoral microcirculation system, alludes to the ability of cancer cells to organize in three-dimensional (3D) channel-like architectures. It also supplies the tumors with nutrients and oxygen. Both mechanisms operate in a coordinated way; however, their functions in breast cancer stem-like cells and their regulation by microRNAs remain elusive...
February 9, 2024: Non-Coding RNA