Daniel Edward Horner, Sarah Davis, Abdullah Pandor, Helen Shulver, Steve Goodacre, Daniel Hind, Saleema Rex, Michael Gillett, Matthew Bursnall, Xavier Griffin, Mark Holland, Beverley Jane Hunt, Kerstin de Wit, Shan Bennett, Robin Pierce-Williams
BACKGROUND: Pharmacological prophylaxis during hospital admission can reduce the risk of acquired blood clots (venous thromboembolism) but may cause complications, such as bleeding. Using a risk assessment model to predict the risk of blood clots could facilitate selection of patients for prophylaxis and optimise the balance of benefits, risks and costs. OBJECTIVES: We aimed to identify validated risk assessment models and estimate their prognostic accuracy, evaluate the cost-effectiveness of different strategies for selecting hospitalised patients for prophylaxis, assess the feasibility of using efficient research methods and estimate key parameters for future research...
April 2024: Health Technology Assessment: HTA