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https://www.readbyqxmd.com/read/28439995/scleromyxoedema-in-a-dog
#1
Aurore F Laprais, Petra Bizikova, Erin W Lashnits, Alison Tucker, Keith E Linder
BACKGROUND: In humans, scleromyxoedema is a chronic progressive skin condition traditionally characterized by deposits of mucin, increased number of fibroblasts and fibrosis in the skin, and by systemic disease. Thyroid disease is typically absent. A monoclonal gammopathy is usually present, as are other comorbidities. Descriptions of scleromyxoedema in the veterinary literature are limited to a single feline case. One dog, previously reported as having papular mucinosis, exhibited features that matched the more current diagnostic criteria of scleromyxoedema...
April 24, 2017: Veterinary Dermatology
https://www.readbyqxmd.com/read/28374103/a-validation-method-for-near-infrared-spectroscopy-based-tissue-oximeters-for-cerebral-and-somatic-tissue-oxygen-saturation-measurements
#2
Paul B Benni, David MacLeod, Keita Ikeda, Hung-Mo Lin
We describe the validation methodology for the NIRS based FORE-SIGHT ELITE(®) (CAS Medical Systems, Inc., Branford, CT, USA) tissue oximeter for cerebral and somatic tissue oxygen saturation (StO2) measurements for adult subjects submitted to the United States Food and Drug Administration (FDA) to obtain clearance for clinical use. This validation methodology evolved from a history of NIRS validations in the literature and FDA recommended use of Deming regression and bootstrapping statistical validation methods...
April 3, 2017: Journal of Clinical Monitoring and Computing
https://www.readbyqxmd.com/read/28338892/embodiment-and-schizophrenia-a-review-of-implications-and-applications
#3
Wolfgang Tschacher, Anne Giersch, Karl Friston
In recent decades, embodiment has become an influential concept in psychology and cognitive neuroscience. Embodiment denotes the study of the reciprocal (causal) relationships between mind and body, with the mind not only affecting the body but also vice versa. Embodied cognition comes to the fore in sensorimotor coupling, predictive coding, and nonverbal behavior. Additionally, the embodiment of the mind constitutes the basis of social interaction and communication, as evident in research on nonverbal synchrony and mimicry...
March 3, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28282814/the-synucleinopathies-twenty-years-on
#4
Michel Goedert, Ross Jakes, Maria Grazia Spillantini
In 2017, it is two hundred years since James Parkinson provided the first complete clinical description of the disease named after him, fifty years since the introduction of high-dose D,L-DOPA treatment and twenty years since α-synuclein aggregation came to the fore. In 1998, multiple system atrophy joined Parkinson's disease and dementia with Lewy bodies as the third major synucleinopathy. Here we review our work, which led to the identification of α-synuclein in Lewy bodies, Lewy neurites and Papp-Lantos bodies, as well as what has happened since...
2017: Journal of Parkinson's Disease
https://www.readbyqxmd.com/read/28280581/cultural-factors-that-affected-the-spatial-and-temporal-epidemiology-of-kuru
#5
J T Whitfield, W H Pako, J Collinge, M P Alpers
Kuru is a prion disease which became epidemic among the Fore and surrounding linguistic groups in Papua New Guinea, peaking in the late 1950s. It was transmitted during the transumption (endocannibalism) of dead family members at mortuary feasts. In this study, we aimed to explain the historical spread and the changing epidemiological patterns of kuru by analysing factors that affected its transmission. We also examined what cultural group principally determined a family's behaviour during mortuary rituals...
January 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28254458/the-cortical-spatiotemporal-correlate-of-otolith-stimulation-vestibular-evoked-potentials-by-body-translations
#6
M Ertl, M Moser, R Boegle, J Conrad, P Zu Eulenburg, M Dieterich
The vestibular organ senses linear and rotational acceleration of the head during active and passive motion. These signals are necessary for bipedal locomotion, navigation, the coordination of eye and head movements in 3D space. The temporal dynamics of vestibular processing in cortical structures have hardly been studied in humans, let alone with natural stimulation. The aim was to investigate the cortical vestibular network related to natural otolith stimulation using a hexapod motion platform. We conducted two experiments, 1...
February 22, 2017: NeuroImage
https://www.readbyqxmd.com/read/28246443/study-of-the-dairy-characters-of-lactating-murrah-buffaloes-on-the-basis-of-body-parts-measurements
#7
Sandeep Dhillod, Dipankar Kar, C S Patil, Subhasish Sahu, Narender Singh
AIM: The aim of the study was to correlate the milk yield of Murrah buffaloes with certain body parts measurements. MATERIALS AND METHODS: A total of 70 lactating Murrah buffaloes were selected from Buffalo Farm, Lala Lajpat Rai University of Veterinary and Animal Science, Hisar and were randomly selected in a range from first to fifth parity. Traits studied were 305 days milk yield (MY), body weight (BW), body length (BL), muzzle width (MW), height at wither (HW), abdominal girth (AG), chest girth (CG), body depth fore, body depth rear, hip bone distance (HBD), pin bone distance (PBD), skin thickness (STK), and tail length (TL)...
January 2017: Veterinary World
https://www.readbyqxmd.com/read/28243533/gait-changes-in-a-line-of-mice-artificially-selected-for-longer-limbs
#8
Leah M Sparrow, Emily Pellatt, Sabrina S Yu, David A Raichlen, Herman Pontzer, Campbell Rolian
In legged terrestrial locomotion, the duration of stance phase, i.e., when limbs are in contact with the substrate, is positively correlated with limb length, and negatively correlated with the metabolic cost of transport. These relationships are well documented at the interspecific level, across a broad range of body sizes and travel speeds. However, such relationships are harder to evaluate within species (i.e., where natural selection operates), largely for practical reasons, including low population variance in limb length, and the presence of confounding factors such as body mass, or training...
2017: PeerJ
https://www.readbyqxmd.com/read/28163879/aerodynamic-evaluation-of-wing-shape-and-wing-orientation-in-four-butterfly-species-using-numerical-simulations-and-a-low-speed-wind-tunnel-and-its-implications-for-the-design-of-flying-micro-robots
#9
Alejandro Ortega Ancel, Rodney Eastwood, Daniel Vogt, Carter Ithier, Michael Smith, Rob Wood, Mirko Kovač
Many insects are well adapted to long-distance migration despite the larger energetic costs of flight for small body sizes. To optimize wing design for next-generation flying micro-robots, we analyse butterfly wing shapes and wing orientations at full scale using numerical simulations and in a low-speed wind tunnel at 2, 3.5 and 5 m s(-1). The results indicate that wing orientations which maximize wing span lead to the highest glide performance, with lift to drag ratios up to 6.28, while spreading the fore-wings forward can increase the maximum lift produced and thus improve versatility...
February 6, 2017: Interface Focus
https://www.readbyqxmd.com/read/28162265/foreing-body-of-the-rectum
#10
Elena Romera Barba, Rafael González-Costea Martínez, María Inmaculada Navarro García, José Luis Vázquez Rojas
No abstract text is available yet for this article.
February 2, 2017: Cirugía Española
https://www.readbyqxmd.com/read/28145055/manipulated-changes-in-limb-mass-and-rotational-inertia-in-trotting-dogs-canis-lupus-familiaris-and-their-effect-on-limb-kinematics
#11
Brandon M Kilbourne, David R Carrier
While the mass distribution of limbs is known to influence the metabolic energy consumed during locomotion, it remains unknown how the mass distribution of limbs may influence overall limb kinematics and whether the influence of limb mass distribution on limb kinematics differs between fore- and hindlimbs. To examine limb mass distribution's influence upon fore- and hindlimb kinematics, temporal stride parameters and swing phase joint kinematics were recorded from four dogs trotting on a treadmill with 0.5% and 1...
February 1, 2017: Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology
https://www.readbyqxmd.com/read/28127679/motion-illusion-evidence-towards-human-vestibulo-thalamic-projections
#12
Aasef G Shaikh, Dominik Straumann, Antonella Palla
Contemporary studies speculated that cerebellar network responsible for motion perception projects to the cerebral cortex via vestibulo-thalamus. Here, we sought for the physiological properties of vestibulo-thalamic pathway responsible for the motion perception. Healthy subjects and the patient with focal vestibulo-thalamic lacunar stroke spun a hand-held rheostat to approximate the value of perceived angular velocity during whole-body passive earth-vertical axis rotations in yaw plane. Vestibulo-ocular reflex was simultaneously measured with high-resolution search coils (paradigm 1)...
January 27, 2017: Cerebellum
https://www.readbyqxmd.com/read/28087353/thiolated-polymers-as-mucoadhesive-drug-delivery-systems
#13
REVIEW
Sarah Duggan, Wayne Cummins, Orla O' Donovan, Helen Hughes, Eleanor Owens
Mucoadhesion is the process of binding a material to the mucosal layer of the body. Utilising both natural and synthetic polymers, mucoadhesive drug delivery is a method of controlled drug release which allows for intimate contact between the polymer and a target tissue. It has the potential to increase bioavailability, decrease potential side effects and offer protection to more sensitive drugs such as proteins and peptide based drugs. The thiolation of polymers has, in the last number of years, come to the fore of mucoadhesive drug delivery, markedly improving mucoadhesion due to the introduction of free thiol groups onto the polymer backbone while also offering a more cohesive polymeric matrix for the slower and more controlled release of drug...
March 30, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28069392/characterization-and-validation-of-a-split-belt-treadmill-for-measuring-hindlimb-ground-reaction-forces-in-able-bodied-and-spinalized-felines
#14
Marko Dimiskovski, Richard Scheinfield, Dwight Higgin, Alexander Krupka, Michel A Lemay
BACKGROUND: The measurement of ground reaction forces (GRFs) in animals trained to locomote on a treadmill after spinal cord injury (SCI) could prove valuable for evaluating training outcomes; however, quantitative measures of the GRFs in spinal felines are limited. NEW METHOD: A split belt treadmill was designed and constructed to measure the GRFs of feline hindlimbs during stepping. The treadmill consists of two independent treadmill assemblies, each mounted on a force plate...
February 15, 2017: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/27847346/scene-segmentation-in-early-visual-cortex-during-suppression-of-ventral-stream-regions
#15
Pablo R Grassi, Natalia Zaretskaya, Andreas Bartels
A growing body of literature suggests that feedback modulation of early visual processing is ubiquitous and central to cortical computation. In particular stimuli with high-level content that invariably activate ventral object responsive regions have been shown to suppress early visual cortex. This suppression was typically interpreted in the framework of predictive coding and feedback from ventral regions. Here we examined early visual modulation during perception of a bistable Gestalt illusion that has previously been shown to be mediated by dorsal parietal cortex rather than by ventral regions that were not activated...
February 1, 2017: NeuroImage
https://www.readbyqxmd.com/read/27811299/a-general-relationship-links-gait-mechanics-and-running-ground-reaction-forces
#16
Kenneth P Clark, Laurence J Ryan, Peter G Weyand
The relationship between gait mechanics and running ground reaction forces is widely regarded as complex. This viewpoint has evolved primarily via efforts to explain the rising edge of vertical force-time waveforms observed during slow human running. Existing theoretical models do provide good rising-edge fits, but require more than a dozen input variables to sum the force contributions of four or more vague components of the body's total mass (mb). Here, we hypothesized that the force contributions of two discrete body mass components are sufficient to account for vertical ground reaction force-time waveform patterns in full (stance foot and shank, m1=0...
January 15, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/27741569/skin-of-the-red-eye-tree-frog-agalychnis-callidryas-hylidae-phyllomedusinae-contains-lipid-glands-of-the-type-described-in-the-genus-phyllomedusa
#17
Elisa Rota, Gianfranco Tanteri, Gilberto Montori, Filippo Giachi, Giovanni Delfino, David M Sever
Several anuran species of the genus Phyllomedusa are known to possess specialized cutaneous glands producing lipids and exhibit a peculiar wiping behavior. This behavior is a stereotyped repertory of fore and hind limb movements distributing hydrophobic molecules onto the body surface and reducing evaporative water loss. No reports are presently available on the occurrence of lipid glands in other phyllomedusine genera, and data on the structure of the secretory units specialized for the production of cutaneous lipids are still unclear...
October 14, 2016: Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology
https://www.readbyqxmd.com/read/27704614/variation-in-food-availability-mediate-the-impact-of-density-on-cannibalism-growth-and-survival-in-larval-yellow-spotted-mountain-newts-neurergus-microspilotus-implications-for-captive-breeding-programs
#18
Somaye Vaissi, Mozafar Sharifi
In this study, we examined cannibalistic behavior, growth, metamorphosis, and survival in larval and post-metamorph endangered yellow spotted mountain newts Neurergus microspilotus hatched and reared in a captive breeding facility. We designed a 2 × 2 factorial experiment, crossing two levels of food with two levels of density including high food/high density, high food/low density, low food/high density, and low food/low density. The level of cannibalistic behavior (including the loss of fore and hind limbs, missing toes, tail, gills, body damage, and whole body consumption) changed as the larvae grew, from a low level during the first 4 weeks, peaking from weeks 7 to 12, and then dropped during weeks 14-52...
November 2016: Zoo Biology
https://www.readbyqxmd.com/read/27701288/a-new-species-of-salamander-of-the-genus-hynobius%C3%A2-amphibia-caudata-hynobiidae-from-south-korea
#19
Mi-Sook Min, Hae-Jun Baek, Jae-Young Song, Min Ho Chang, Nikolay A Jr Poyarkov
We describe a new species of lentic-breeding Hynobius salamander from the Naro Islands, near the village of Bongrae-myeon, Goheung-gun, Jeollanam-do, South Korea, on the basis of results of morphological, ecological and genetic analyses. Hynobius unisacculus sp. nov. is distinguished from its congeners by a combination of the following morphological attributes: (1) comparatively small size (adult SVL up to 61 mm; range 38.3-60.3 mm in males and 37.5-59.9 mm in females); (2) relatively slender short limbs; tips of fore- and hindlimbs adpressed on body never meeting, but separated by a large gap (gap of -3...
September 21, 2016: Zootaxa
https://www.readbyqxmd.com/read/27701219/new-species-and-records-of-microveliinae-and-veliinae-hemiptera-heteroptera-veliidae-from-colombia
#20
Fredy Molano, Felipe Ferraz Figueiredo Moreira, Irina Morales
Euvelia orinoquia sp. nov. and E. meta sp. nov. from eastern Colombia are described, illustrated, and included in an updated identification key to the species of the genus. The former can be diagnosed by body length 2.30-2.50 mm, male fore femur without tufts of setae, longitudinal black stripe of female pronotum almost twice as wide as length of antennomere I, and female connexiva grayish black with silvery pruinosity on mesal portion, reddish on lateral portion. Euvelia meta sp. nov. can be diagnosed by female body length about 1...
September 29, 2016: Zootaxa
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