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https://www.readbyqxmd.com/read/28453843/inflammation-and-immune-activation-in-antiretroviral-treated-human-immunodeficiency-virus-type-1-infected-african-infants-and-rotavirus-vaccine-responses
#1
Priyanka Uprety, Jane C Lindsey, Myron J Levin, Kaitlin Rainwater-Lovett, Carrie Ziemniak, Mutsa Bwakura-Dangarembizix, Susan S Kaplan, Micki Nelson, Amanda Zadzilka, Adriana Weinberg, Deborah Persaud
00880698.
March 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28446443/enteritis-with-pneumatosis-intestinalis-following-rotavirus-immunisation-in-an-infant-with-short-bowel-syndrome
#2
Robert N Lopez, Usha Krishnan, Chee Y Ooi
Rotavirus vaccines now form part of the national immunisation schedule in many countries. Contraindications to its use are few but do not currently include infants with short bowel syndrome (SBS). We present a nearly 3-month-old boy with SBS who developed enteritis with pneumatosis intestinalis following administration of the Rotarix vaccine.
April 26, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28446379/group-a-rotavirus-genotypes-in-hospital-acquired-gastroenteritis-in-italy-2012-14
#3
G Ianiro, R Delogu, L Fiore, M Monini, F M Ruggeri
BACKGROUND: Group A rotaviruses (RVA) are the leading cause of acute gastroenteritis (AGE) in young (aged <5 years) children, causing ∼250,000 deaths worldwide, mostly in developing countries. Differences on nucleotide sequences of VP7 (G-type) and VP4 (P-type) genes are the basis for the binary RVA nomenclature. Although at least 32 G-types and 47 P-types of rotavirus are presently known, most RVA infections in humans worldwide are related to five major G/P combinations: G1P[8], G2P[4], G3P[8], G4P[8], and G9P[8]...
April 8, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28444323/effectiveness-of-rotavirus-vaccination-a-systematic-review-of-the-first-decade-of-global-post-licensure-data-2006-2016
#4
Christine L Jonesteller, Eleanor Burnett, Catherine Yen, Jacqueline E Tate, Umesh D Parashar
Two rotavirus vaccines, Rotarix (RV1) and RotaTeq (RV5), were licensed for global use in 2006. A systematic review of 48 peer-reviewed articles with post-licensure data from 24 countries showed a median RV1 vaccine effectiveness (VE) of 84%, 75%, and 57% in low, medium, and high child mortality countries, respectively, and RV5 VE of 90% in low and 45% in high child mortality countries. A partial vaccine series provided considerable protection, but not to the same level as a full series. VE tended to decline in the second year of life, particularly in medium and high mortality settings, and tended to be greater against more severe rotavirus disease...
April 21, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28444305/dissemination-of-gastroenteric-viruses-in-the-production-of-lettuce-in-developing-countries-a-public-health-concern
#5
Lucia M C Werneck, Carmen B Vieira, Tulio M Fumian, Thalles Borges Caetano, Jarbas Emílio Dos Santos, Fernando César Ferreira, Marcia Maria Pimenta, Marize P Miagostovich
Investigation of major viruses responsible for acute viral gastroenteritis, such as norovirus (NoV), rotavirus species A (RVA) and human adenovirus (HAdV), was conducted in the mountainous region of the state of Rio de Janeiro in a lettuce-producing area. Irrigation water and lettuce samples were collected at different production stages. Viruses were concentrated using an adsorption-elution method and detected by quantitative polymerase chain reaction (qPCR). We detected HAdV in all collection points, although no virus infectivity was shown...
April 21, 2017: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/28442466/preventing-rotavirus-in-africa
#6
Robert Scott-Jupp
No abstract text is available yet for this article.
April 25, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28442435/effectiveness-of-rotavirus-pentavalent-vaccine-under-a-universal-immunization-program-in-israel-2011-2015-a-case-control-study
#7
Khitam Muhsen, Emilia Anis, Uri Rubinstein, Eias Kassem, Sophy Goren, Lester M Shulman, Moshe Ephros, Daniel Cohen
OBJECTIVES: The use of rotavirus pentavalent vaccine (RotaTeq) as a sole vaccine within rotavirus universal immunization programs remains limited. We examined the effectiveness of RotaTeq in preventing rotavirus gastroenteritis (RVGE) hospitalization in Israel, after the introduction of universal immunization against the disease. METHODS: A test-negative case-control study included age-eligible children for universal RotaTeq immunization (ages 2-59 months, born in 2011-2015)...
April 22, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28441094/background-rates-of-disease-in-latin-american-children-from-a-rotavirus-vaccine-study
#8
Marc Baay, Kaatje Bollaerts, Claudio Struchiner, Thomas Verstraeten
BACKGROUND: Knowledge of background rates of adverse events is crucial to assess vaccine safety concerns. We used data from a rotavirus vaccine study (Ruiz-Palacios et al., NEJM, 2006) including 63,225 infants from 11 Latin American countries to investigate reporting rates of serious adverse events (SAEs) among these infants, and describe rates by country, gender, age, and season. METHODS: For this randomized, double-blind, placebo-controlled, phase 3 trial, investigators from Argentina, Brazil, Chile, Colombia, Dominican Republic, Honduras, Mexico, Nicaragua, Panama, Peru, and Venezuela recruited 6-to-13-week-old healthy infants...
April 25, 2017: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/28438670/epidemiological-features-and-genetic-characterization-of-virus-strains-in-rotavirus-associated-gastroenteritis-in-children-of-odisha-in-eastern-india
#9
Eileena Mohanty, Bhagirathi Dwibedi, S K Kar, A S Acharya
We have studied the clinical characteristics, severity and seasonality of rotavirus infection and prevalent genotypes in 652 non-rota vaccinated children in Odisha in eastern India. P genotypes were analysed for their association with host blood group antigens. P type of the virus is determined by the VP8* gene, and specific recognition of A - type of Histo - blood group antigen by P[14]VP8* has been reported. VP4, VP7 and VP6 genes of commonly identified G1P[8] strain were compared with genes of the same strain isolated from other parts of India, elsewhere and strains used for Rotarix and Rotateq vaccines...
April 21, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/28438140/a-universal-genome-sequencing-method-for-rotavirus-a-from-human-fecal-samples-which-identifies-segment-reassortment-and-multi-genotype-mixed-infection
#10
Tran Thi Ngoc Dung, Pham Thanh Duy, October M Sessions, Uma K Sangumathi, Voong Vinh Phat, Pham Thi Thanh Tam, Nguyen Thi Nguyen To, Tran My Phuc, Tran Thi Hong Chau, Nguyen Ngoc Minh Chau, Ngoc Nguyen Minh, Guy E Thwaites, Maia A Rabaa, Stephen Baker
BACKGROUND: Genomic characterization of rotavirus (RoV) has not been adopted at large-scale due to the complexity of obtaining sequences for all 11 segments, particularly when feces are used as starting material. METHODS: To overcome these limitations, we developed a novel RoV capture and genome sequencing method combining commercial enzyme immunoassay plates and a set of routinely used reagents. RESULTS: Our approach had a 100% success rate, producing >90% genome coverage for diverse RoV present in fecal samples (Ct < 30)...
April 24, 2017: BMC Genomics
https://www.readbyqxmd.com/read/28434688/stability-of-heat-stable-live-attenuated-rotavirus-vaccine-rotasiil%C3%A2
#11
Sameer P Naik, Jagdish K Zade, Rajendra N Sabale, Sambhaji S Pisal, Ravi Menon, Subhash G Bankar, Sunil Gairola, Rajeev M Dhere
Vaccines currently available across the globe are stored and transported in a continuous cold-chain at 2-8°C or below -20°C. A temperature excursion outside this range affects the potency of the vaccines. Such vaccines need to be discarded leading wastage. The Rotavirus disease burden is predominantly reported in developing and low-income countries and therefore, has entered or poised to enter their national immunization programs. These countries already have several limitations for effective storage, maintenance and distribution of vaccines in a cold-chain and this introduction is expected to further stress this fragile ecosystem...
April 20, 2017: Vaccine
https://www.readbyqxmd.com/read/28432676/bifidobacterium-adolescentis-dsm-20083-and-lactobacillus-casei-lafti-l26-dsl-probiotics-able-to-block-the-in-vitro-adherence-of-rotavirus-in-ma104-cells
#12
Karem Prunella Fernandez-Duarte, Nury Nathalia Olaya-Galán, Sandra Patricia Salas-Cárdenas, Jazmin Lopez-Rozo, Maria Fernanda Gutierrez-Fernandez
Rotavirus is the leading worldwide cause of gastroenteritis in children under five years of age. Even though there are some available vaccines to prevent the disease, there are limited strategies for challenging diarrhea induced by rotavirus infection. For this reason, researchers are constantly searching for other approaches to control diarrhea by means of probiotics. In order to demonstrate the ability of some probiotic bacteria to interfere with the in vitro rotavirus infection in MA104 cells, strains of Lactobacillus sp...
April 21, 2017: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/28431785/multicausal-etiology-of-the-enteric-syndrome-in-rabbits-from-mexico
#13
Virginia G García-Rubio, Linda G Bautista-Gómez, José S Martínez-Castañeda, Camilo Romero-Núñez
Enteropathies in rabbits are difficult to diagnose; their etiology involves pathogens that act synergistically, causing damage to the intestine. The aim of the present study was isolate enteric pathogens from rabbits in Mexico. Using parasitological, bacteriological and molecular analyses, we screened 58 samples of the intestinal content of rabbits having a clinical history of enteric disease from the southeastern part of the State of Mexico. Out of the 58 samples analyzed, a total of 86 identifications were made, Eimeria spp...
April 18, 2017: Revista Argentina de Microbiología
https://www.readbyqxmd.com/read/28431126/global-impact-of-rotavirus-vaccination-on-childhood-hospitalizations-and-mortality-from-diarrhea
#14
E Anthony S Nelson, A Duncan Steele
No abstract text is available yet for this article.
April 18, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28430997/global-impact-of-rotavirus-vaccination-on-childhood-hospitalizations-and-mortality-from-diarrhea
#15
Eleanor Burnett, Christine L Jonesteller, Jacqueline E Tate, Catherine Yen, Umesh D Parashar
In 2006, two rotavirus vaccines were licensed. We summarize the impact of rotavirus vaccination on hospitalizations and deaths from rotavirus and all-cause acute gastroenteritis (AGE) during the first 10 years since vaccine licensure, including recent evidence from high child mortality countries. We used standardized guidelines (PRISMA) guidelines to identify observational evaluations of rotavirus vaccine impact among children <5 years of age that presented at least 12 months of pre- and post-vaccine introduction surveillance data...
April 18, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28429133/predominance-of-new-g9p-8-rotaviruses-closely-related-to-turkish-strains-in-nizhny-novgorod-russia
#16
T A Sashina, O V Morozova, N V Epifanova, N A Novikova
Genotype G9P[8] rotaviruses are rare in the territory of Russia. They were found in Nizhny Novgorod only in 2011-2012 for the first time, when their proportion was 25.9%. During the next two seasons, G9P[8] strains were detected in only 1.8% of cases. Their proportion substantially increased again in 2014, and they became predominant in the city by 2016. Phylogenetic analysis on the basis of gene VP7 nucleotide sequences showed that this increase was accompanied by the emergence of new strains in the population...
April 20, 2017: Archives of Virology
https://www.readbyqxmd.com/read/28427846/vaccines-are-different-a-systematic-review-of-budget-impact-analyses-of-vaccines
#17
REVIEW
Priscilla Magalhaes Loze, Luciana Bertholim Nasciben, Ana Marli Christovam Sartori, Alexander Itria, Hillegonda Maria Dutilh Novaes, Patrícia Coelho de Soárez
INTRODUCTION: Several countries require manufacturers to present a budget impact analysis (BIA), together with a cost-effectiveness analysis, to support national funding requests. However, guidelines for conducting BIA of vaccines are scarce. OBJECTIVES: To analyze the methodological approaches used in published budget impact analysis (BIA) of vaccines, discussing specific methodological issues related to vaccines. MATERIAL AND METHODS: This systematic review of the literature on BIA of vaccines was carried out in accordance with the Centre for Reviews and Dissemination - CRD guidelines...
April 17, 2017: Vaccine
https://www.readbyqxmd.com/read/28426777/rotavirus-genome-replication-some-assembly-required
#18
Courtney P Long, Sarah M McDonald
No abstract text is available yet for this article.
April 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28425908/rotavirus-vaccine-breastfeeding-and-other-factors-that-could-affect-susceptibility-to-gastroenteritis-in-young-children
#19
Amy Elizabeth Murphy
No abstract available.
April 20, 2017: Canadian Journal of Public Health. Revue Canadienne de Santé Publique
https://www.readbyqxmd.com/read/28422995/characterization-of-rotavirus-infection-in-children-with-acute-gastroenteritis-in-bengo-province-northwestern-angola-prior-to-vaccine-introduction
#20
Carolina Gasparinho, João Piedade, Maria Clara Mirante, Cristina Mendes, Carlos Mayer, Susana Vaz Nery, Miguel Brito, Claudia Istrate
BACKGROUND: Rotavirus group A (RVA) is considered the leading cause of pediatric diarrhea, responsible for the high burden of diarrheal diseases in sub-Saharan Africa. Despite recent studies, the existent data are scarce for some African countries like Angola, a country with one of the highest RVA-related death estimates. The aim of this study was to determine the RVA detection rate and circulating genotypes in children less than five years of age with acute gastroenteritis attended at the Bengo General Hospital in Caxito, Bengo province, Angola, before vaccine introduction...
2017: PloS One
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