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https://www.readbyqxmd.com/read/29141673/a-customized-fixation-plate-with-novel-structure-designed-by-topological-optimization-for-mandibular-angle-fracture-based-on-finite-element-analysis
#1
Yun-Feng Liu, Ying-Ying Fan, Xian-Feng Jiang, Dale A Baur
BACKGROUND: The purpose of this study was to design a customized fixation plate for mandibular angle fracture using topological optimization based on the biomechanical properties of the two conventional fixation systems, and compare the results of stress, strain and displacement distributions calculated by finite element analysis (FEA). METHODS: A three-dimensional (3D) virtual mandible was reconstructed from CT images with a mimic angle fracture and a 1 mm gap between two bone segments, and then a FEA model, including volume mesh with inhomogeneous bone material properties, three loading conditions and constraints (muscles and condyles), was created to design a customized plate using topological optimization method, then the shape of the plate was referenced from the stress concentrated area on an initial part created from thickened bone surface for optimal calculation, and then the plate was formulated as "V" pattern according to dimensions of standard mini-plate finally...
November 15, 2017: Biomedical Engineering Online
https://www.readbyqxmd.com/read/29135727/comparative-cost-analysis-of-single-and-mutli-stage-temporal-deformity-correction-following-neurosurgical-procedures
#2
Anthony Asemota, Gabriel F Santiago, Susan Zhong, Chad R Gordon
PURPOSE: Temporal hollowing deformity (THD) is a visible concavity/convexity in the temporal fossa; a complication often seen following neurosurgical/craniofacial procedures. Although numerous techniques have been described, no study to date has shown the healthcare costs associated with temporal hollowing correction surgery. Thus, the purpose here is to compare and contrast the direct costs related to temporal cranioplasty using various methods including: liquid poly-methyl-methacrylate (PMMA) implants with screw fixation, prebent, modified titanium mesh implants, and customized cranial implants (CCIs) with dual-purpose design...
November 9, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29134243/-implants-for-genital-prolapse-pro-mesh-surgery
#3
REVIEW
J Neymeyer, D-E Moldovan, K Kornienko, K Miller, A Weichert
There has been an overall increase in pelvic organ prolapse due to demographic changes (increased life expectancy). Increasing sociocultural demands of women require treatments that are more effective with methods that are more successful. In the treatment of pelvic floor insufficiency and uterovaginal prolapse, pelvic floor reconstructions with mesh implants have proven to be superior to conventional methods such as the classic colporrhaphy, reconstructions with biomaterial, and native tissue repair in appropriately selected patients and when applying exact operation techniques, especially because of good long-term results and low recurrence rates...
November 13, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/29084228/a-method-to-increase-reproducibility-in-adult-ventricular-myocyte-sizing-and-flow-cytometry-avoiding-cell-size-bias-in-single-cell-preparations
#4
Javier E López, Katrin Jaradeh, Emmanuel Silva, Shadi Aminololama-Shakeri, Paul C Simpson
RATIONALE: Flow cytometry (FCM) of ventricular myocytes (VMs) is an emerging technology in adult cardiac research that is challenged by the wide variety of VM shapes and sizes. Cellular variability and cytometer flow cell size can affect cytometer performance. These two factors of variance limit assay validity and reproducibility across laboratories. Washing and filtering of ventricular cells in suspension are routinely done to prevent cell clumping and minimize data variability without the appropriate standardization...
2017: PloS One
https://www.readbyqxmd.com/read/29075973/seroma-following-transabdominal-preperitoneal-patch-plasty-tapp-incidence-risk-factors-and-preventive-measures
#5
F Köckerling, R Bittner, D Adolf, R Fortelny, H Niebuhr, F Mayer, C Schug-Pass
BACKGROUND: The reported range of seroma formation in the literature after TEP repair is between 0.5 and 12.2% and for TAPP between 3.0 and 8.0%. Significant clinical factors associated with seroma formation include old age, a large hernia defect, an extension of the hernia sac into the scrotum, as well as the presence of a residual indirect sac. Seroma formation is a frequent complication of laparoendoscopic mesh repair of moderate to large-size direct (medial) inguinal hernia defects...
October 26, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29075969/what-are-the-influencing-factors-for-chronic-pain-following-tapp-inguinal-hernia-repair-an-analysis-of-20-004-patients-from-the-herniamed-registry
#6
H Niebuhr, F Wegner, M Hukauf, M Lechner, R Fortelny, R Bittner, C Schug-Pass, F Köckerling
BACKGROUND: In inguinal hernia repair, chronic pain must be expected in 10-12% of cases. Around one-quarter of patients (2-4%) experience severe pain requiring treatment. The risk factors for chronic pain reported in the literature include young age, female gender, perioperative pain, postoperative pain, recurrent hernia, open hernia repair, perioperative complications, and penetrating mesh fixation. This present analysis of data from the Herniamed Hernia Registry now investigates the influencing factors for chronic pain in male patients after primary, unilateral inguinal hernia repair in TAPP technique...
October 26, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29063325/comparative-study-of-sutureless-fixation-of-lightweight-surgical-meshes-for-hernia-repair-in-a-rat-model
#7
M V Anurov, G V Khachatrian, S M Titkova, P S Velangi, M D Polivoda, A P Oettinger
The aim of this study was to compare the efficacy of different methods of sutureless fixation of lightweight meshes made of different polymers for repair of experimental hernias. Two lateral hernia defects were modeled in male rats and covered with polyester and polypropylene prostheses. The meshes were fixed with Histacryl glue (group 1), or self-gripping meshes were used (group 2), or the meshes were implanted without fixation (group 3). On day 5 after surgery, mesh position and efficiency of fixation were evaluated...
October 2017: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/29045876/elastic-properties-of-pore-spanning-apical-cell-membranes-derived-from-mdck-ii-cells
#8
Stefan Nehls, Andreas Janshoff
The mechanical response of adherent, polarized cells to indentation is frequently attributed to the presence of an endogenous actin cortex attached to the inner leaflet of the plasma membrane. Here, we scrutinized the elastic properties of apical membranes separated from living cells and attached to a porous mesh in the absence of intracellular factors originating from the cytosol, organelles, the substrate, neighbors, and the nucleus. We found that a tension-based model describes the data very well providing essentially the prestress of the shell generated by adhesion of the apical membrane patches to the pore rim and the apparent area compressibility modulus, an intrinsic elastic modulus modulated by the surface excess stored in membrane reservoirs...
October 17, 2017: Biophysical Journal
https://www.readbyqxmd.com/read/29038834/the-treatment-of-post-hysterectomy-vaginal-vault-prolapse-a-systematic-review-and-meta-analysis
#9
REVIEW
Anne-Lotte W M Coolen, Bich Ngoc Bui, Viviane Dietz, Rui Wang, Aafke P A van Montfoort, Ben Willem J Mol, Jan-Paul W R Roovers, Marlies Y Bongers
INTRODUCTION AND HYPOTHESIS: The treatment of post-hysterectomy vaginal vault prolapse (VVP) has been investigated in several randomized clinical trials (RCTs), but a systematic review of the topic is still lacking. The aim of this study is to compare the effectiveness of treatments for VVP. METHODS: We performed a systematic review and meta-analysis of the literature on the treatment of VVP found in PubMed and Embase. Reference lists of identified relevant articles were checked for additional articles...
October 16, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/29027023/how-we-do-it-repair-of-large-perineal-hernia-after-abdominoperineal-resection
#10
J Li, W Zhang
BACKGROUND: Symptomatic perineal hernia is a rare complication after abdominoperineal resection (APR). Management of these hernias is challenging. The recurrence rate after surgical repair is high because of the difficulty of prosthetic material fixation; there is no consensus regarding the best method of repair. METHODS: We introduced a novel combined laparoscopic-perineal dual fixation technique in the repair of perineal hernias after APR. This technique begins with a perineal approach under laparoscopic vision...
October 12, 2017: Hernia: the Journal of Hernias and Abdominal Wall Surgery
https://www.readbyqxmd.com/read/29017309/langerhans-cell-histiocytosis-of-the-thoracic-spine-in-an-adult
#11
Myeong Cheol Kim, Sun Hee Sung, Yongjae Cho
We report a case of a 45-year-old man with a complaint of both leg weakness and hypoesthesia. Radiological evaluation revealed an osteolytic lesion of the ninth thoracic vertebra. The patient underwent posterior corpectomy with total excision of the tumor, mesh cage insertion with posterior screw fixation and subsequent radiotherapy. Histology confirmed the diagnosis of Langerhans cell histiocytosis (LCH). This case report presents the diagnostic work-up, histopathological evaluation, and the treatment procedures of rare LCH in the thoracic spine...
September 2017: Korean Journal of Spine
https://www.readbyqxmd.com/read/28980021/comparison-of-strength-of-sacrocolpopexy-mesh-attachment-using-barbed-and-nonbarbed-sutures
#12
Marjorie L Pilkinton, Gregory C Levine, Laura Bennett, Harvey A Winkler, Dara F Shalom, Peter S Finamore
INTRODUCTION AND HYPOTHESIS: We aimed to assess the pull-out strength of barbed and nonbarbed sutures used in sacrocolpopexy mesh fixation. We hypothesized there are no differences in the force needed to dislodge mesh from tissue using barbed and nonbarbed sutures of similar size. METHODS: Using the rectus fascia of three unembalmed cadavers, a 6 × 3 cm strip of polypropylene mesh was anchored to the fascia with sutures. The barbed sutures investigated were 2-0 V-Loc 180 (nine trials) and 3-0 bidirectional Quill™ SRS PDO (five trials)...
October 4, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28958271/operative-outcomes-after-open-abdominal-wall-reconstruction-with-retromuscular-mesh-fixation-using-fibrin-glue-versus-transfascial-sutures
#13
COMPARATIVE STUDY
Adam S Weltz, Udai S Sibia, H Reza Zahiri, Alexa Schoeneborn, Adrian Park, Igor Belyansky
Ideal fixation techniques have not been fully elucidated at the time of complex open abdominal wall reconstruction (AWR). We compared operative outcomes and quality of life with retromuscular mesh fixation using fibrin glue (FG) versus transfascial sutures (TS). Retrospective review identified complex hernia patients who underwent open AWR with mesh from November 2012 through April 2016. Multivariate analysis examined postoperative outcomes between groups. Quality of life was assessed using the Carolinas Comfort Scale...
September 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28938113/a-spatial-interactome-reveals-the-protein-organization-of-the-algal-co2-concentrating-mechanism
#14
Luke C M Mackinder, Chris Chen, Ryan D Leib, Weronika Patena, Sean R Blum, Matthew Rodman, Silvia Ramundo, Christopher M Adams, Martin C Jonikas
Approximately one-third of global CO2 fixation is performed by eukaryotic algae. Nearly all algae enhance their carbon assimilation by operating a CO2-concentrating mechanism (CCM) built around an organelle called the pyrenoid, whose protein composition is largely unknown. Here, we developed tools in the model alga Chlamydomonas reinhardtii to determine the localizations of 135 candidate CCM proteins and physical interactors of 38 of these proteins. Our data reveal the identity of 89 pyrenoid proteins, including Rubisco-interacting proteins, photosystem I assembly factor candidates, and inorganic carbon flux components...
September 21, 2017: Cell
https://www.readbyqxmd.com/read/28925271/-the-results-of-five-years-follow-up-prospective-study-of%C3%A2-vaginal-prolapse-repaired-by-prolift-total-mesh-surgery-or%C3%A2-sacrospinous-fixation
#15
P Kraus, L Krofta, M Krčmář, I Urbánková, O Gojiš, K Grogregin, J Feyereisl
OBJECTIVE: The aim of the study is to compare the results of five years follow-up prospective study of vaginal prolapse repaired by prolift total mesh surgery or sacrospinous fixation. STUDY DESIGN: A single-center prospective, cohort study, in patients with defect grade II and more by POP-Q. SETTING: The Institute for the Care of Mather and Child; 3rd Medical Faculty Charles university, Prague. METHODS: Comparison of the preoperative state and the five years after the operation according POP Q, ICIQ-SF, PISQ 12, VAS...
2017: Ceská Gynekologie
https://www.readbyqxmd.com/read/28922462/vaginal-mesh-repair-systems-for-pelvic-organ-prolapse-anatomical-study-comparing-transobturator-trangluteal-versus-single-incision-techniques
#16
Giuseppe Campagna, Giovanni Panico, Andrea Morciano, Pierre Gadonneix, Vincent Delmas, Mauro Cervigni, Alfredo Ercoli, Giovanni Scambia
INTRODUCTION: The present study aim to compare the anatomic landmarks of two pelvic floor repair systems, in order to identify the potential neurovascular lesions related to different mesh fixation techniques. METHODS: Abdominal and perineal dissections of 10 fresh cadavers after prolapse surgery using transobturator/transgluteal versus single incision techniques. Neuro-vascular structures of obturator region and perineum were isolated. Distances between needles and anatomical structures were measured...
September 18, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28916960/a-novel-approach-using-the-enhanced-view-totally-extraperitoneal-etep-technique-for-laparoscopic-retromuscular-hernia-repair
#17
Igor Belyansky, Jorge Daes, Victor Gheorghe Radu, Ramana Balasubramanian, H Reza Zahiri, Adam S Weltz, Udai S Sibia, Adrian Park, Yuri Novitsky
BACKGROUND: The enhanced-view totally extraperitoneal (eTEP) technique has been previously described for Laparoscopic Inguinal Hernia Repair. We present a novel application of the eTEP access technique for the repair of ventral and incisional hernias. METHODS: Retrospective review of consecutive laparoscopic retromuscular hernia repair cases utilizing the eTEP access approach from five hernia centers between August 2015 and October 2016 was conducted. Patient demographics, hernia characteristics, operative details, perioperative complications, and quality of life outcomes utilizing the Carolina's Comfort Scale (CCS) were included in our data analysis...
September 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28915205/postoperative-pain-after-laparoscopic-repair-of-primary-umbilical-hernia-titanium-tacks-versus-absorbable-tacks-a-prospective-comparative-cohort-analysis-of-80-patients-with-a-long-term-follow-up
#18
Vincent M A Stirler, Erol G Nallayici, Robbert J de Haas, Johan T F J Raymakers, Srdjan Rakic
We investigated if a novel fixation device with absorbable tacks (Securestrap) causes less early and chronic postoperative pain after laparoscopic repair with a double-crown mesh fixation of ventral abdominal wall hernia when compared with the standard fixation device with nonabsorbable titanium tacks (Protack). The primary outcome measure was early postoperative pain at 2, 6, and 12 weeks postoperatively. The secondary outcome measure was chronic postoperative pain measured ≥18 months after surgery. Pain levels were assessed using a visual analog scale ranging from 0 (no pain) to 100 mm (excruciating pain)...
September 14, 2017: Surgical Laparoscopy, Endoscopy & Percutaneous Techniques
https://www.readbyqxmd.com/read/28914338/the-uk-national-prolapse-survey-10%C3%A2-years-on
#19
Swati Jha, Alfred Cutner, Paul Moran
INTRODUCTION AND HYPOTHESIS: To assess trends in the surgical management of pelvic organ prolapse (POP) amongst UK practitioners and changes in practice since a previous similar survey. METHODS: An online questionnaire survey (Typeform Pro) was emailed to British Society of Urogynaecology (BSUG) members. They included urogynaecologists working in tertiary centres, gynaecologists with a designated special interest in urogynaecology and general gynaecologists. The questionnaire included case scenarios encompassing contentious issues in the surgical management of POP and was a revised version of the questionnaire used in the previous surveys...
September 15, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28904521/mesh-displacement-after-bilateral-inguinal-hernia-repair-with-no-fixation
#20
Christiano Marlo Paggi Claus, Gabriela Moreira Rocha, Antonio Carlos Ligocki Campos, João Augusto Nocera Paulin, Julio Cesar Uili Coelho
BACKGROUND AND OBJECTIVES: About 20% of patients with inguinal hernia present bilateral hernias in the diagnosis. In these cases, laparoscopic procedure is considered gold standard approach. Mesh fixation is considered important step toward avoiding recurrence. However, because of cost and risk of pain, real need for mesh fixation has been debated. For bilateral inguinal hernias, there are few specific data about non fixation and mesh displacement. We assessed mesh movement in patients who had undergone laparoscopic bilateral inguinal hernia repair without mesh fixation and compared the results with those obtained in patients with unilateral hernia...
July 2017: JSLS: Journal of the Society of Laparoendoscopic Surgeons
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