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İntraabdominal infections

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https://www.readbyqxmd.com/read/29325351/-analysis-of-risk-factors-and-outcomes-for-delayed-gastric-emptying-following-pancreaticoduodenectomy-a-single-center-experience-of-492-cases
#1
J Yin, Z P Lu, K Zhang, J L Wu, W T Gao, F Guo, J M Chen, J S Wei, P F Wu, D Xu, K R Jiang, Y Miao
Objective: To evaluate risk factors for delayed gastric emptying(DGE)following pancreaticoduodenectomy(PD). Methods: There were 492 consecutive patients who underwent PD in Pancreas Center, the First Affiliated Hospital with Nanjing Medical University between January 2012 and December 2014 were identified from a prospective database.There were 315 male and 177 female patients with a median age of 60.5 years.Univariate and multivariate analyses were performed to investigate the independent risk factors for clinically relevant DGE(CR-DGE)...
January 1, 2018: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/29307988/procalcitonin-in-inflammatory-bowel-disease-drawbacks-and-opportunities
#2
REVIEW
Giuseppe Lippi, Fabian Sanchis-Gomar
The measurement of procalcitonin has recently become a mainstay for the diagnosis and therapeutic management of severe bacterial infections, especially those sustained by Gram-negative bacteria. Therefore, the aim of this article is to provide a narrative overview on the potential role of procalcitonin measurement in patients with inflammatory bowel disease (IBD). According to the available scientific literature, the clinical significance of procalcitonin for diagnosing IBD or monitoring disease activity remains elusive, and its association with disease severity is confined to a limited number of case-control studies, with low sample size...
December 21, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/29248543/plasma-ghrelin-suppression-as-an-early-predictor-for-postoperative-complications-after-pancreatoduodenectomy
#3
Kazuki Sasaki, Tadafumi Asaoka, Hidetoshi Eguchi, Yasunari Fukuda, Yoshifumi Iwagami, Daisaku Yamada, Yasuhiro Miyazaki, Takehiro Noda, Tsuyoshi Takahashi, Kunihito Gotoh, Koichi Kawamoto, Yukinori Kurokawa, Shogo Kobayashi, Shuji Takiguchi, Masaki Mori, Yuichiro Doki
BACKGROUND/OBJECTIVES: The gut peptide hormone ghrelin induces appetite and exhibits an anti-inflammatory effect. Serial perioperative changes in ghrelin have been examined in several surgical procedures, but few in pancreatectomy. The present study analyzed perioperative changes in plasma ghrelin levels after pancreaduodenectomy (PD). METHODS: The study included 24 patients undergoing PD between May 2015 and January 2016 at Osaka University Hospital. Plasma ghrelin and interleukin-6 (IL-6) levels, as well as white blood cells (WBCs) and C-reactive protein (CRP), were measured preoperatively and on postoperative day (POD) 1, 3, 7, and 14 by enzyme-linked immunosorbent assay...
December 5, 2017: Pancreatology: Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]
https://www.readbyqxmd.com/read/29155250/surgical-management-of-acute-appendicitis-in-adults-a-review-of-current-techniques
#4
REVIEW
Maximilian Sohn, Ayman Agha, Stefan Bremer, Kai S Lehmann, Marcus Bormann, Alfred Hochrein
Acute appendicitis is one of the most frequent disorders in abdominal surgery. Therefore, appendectomy is a matter of significant interest in that field. Yet, four different techniques are available: open appendectomy, (conventional) laparoscopic appendectomy, single port laparoscopic appendectomy and NOTES-appendectomy with its different variations. To evaluate the current state of the art in appendectomy a bibliographic search was conducted. All prospectively randomized trials and national register cohort studies published between 1/2010 and 5/2016 were included into the analysis...
December 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/29096346/intraabdominal-abscess-caused-by-stenotrophomonas-maltophilia-a-case-report
#5
Toyomitsu Sawai, Sumako Yoshioka, Nobuko Matsuo, Naofumi Suyama, Hiroshi Mukae
INTRODUCTION: Stenotrophomonas maltophilia usually causes nosocomial infections, but intraabdominal abscesses or organ/space surgical site infection (SSI) secondary to this organism has been rarely reported. Here, we reported a rare case of SSI that presented as intraabdominal abscess caused by S. maltophilia. PRESENTATION OF CASE: A 68-year-old woman presented to our hospital with transverse colon cancer. Further work up with abdominal computed tomography (CT) revealed left renal cell carcinoma...
October 27, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29089105/simultaneous-pancreas-kidney-transplantation-experience-of-the-doce-de-octubre-hospital
#6
Carlos Jiménez-Romero, Alberto Marcacuzco Quinto, Alejandro Manrique Municio, Iago Justo Alonso, Jorge Calvo Pulido, Félix Cambra Molero, Óscar Caso Maestro, Álvaro García-Sesma, Enrique Moreno González
INTRODUCTION: Simultaneous pancreas-kidney transplantation (SPKT) constitutes the therapy of choice for diabetes type1 or type2 associated with end-stage renal disease, because is the only proven method to restore normo-glicemic control in the diabetic patient. METHODS: Retrospective and descriptive study of a series of 175 patients who underwent SPKT from March 1995 to April 2016. We analyze donor and recipient characteristics, perioperative variables and immunosuppression, post-transplant morbi-mortality, patient and graft survival, and risk factors related with patient and graft survival...
October 28, 2017: Cirugía Española
https://www.readbyqxmd.com/read/29079022/factors-associated-with-portomesenteric-venous-thrombosis-after-total-colectomy-with-ileorectal-anastomosis-or-end-ileostomy
#7
Emre Gorgun, Ipek Sapci, Akin Onder, Gokhan Ozuner, David Liska, Luca Stocchi, Conor P Delaney
BACKGROUND: Porto-mesenteric venous thrombosis (PMVT) is an uncommon but serious complication. Data on the risk factors for PMVT following total colectomy with ileorectal anastomosis or end ileostomy (TC/IRA or EI) is limited. This study aimed to evaluate the factors associated with PMVT after TC/IRA or EI. METHODS: Patients who underwent elective TC/IRA or EI between January 2010 and December 2014 were identified from institutional database. Patients who had CT proven PMVT within 30 days of surgery were included in the PMVT positive group...
October 6, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/29062248/evaluation-of-candida-species-and-antifungal-susceptibilities-among-children-with-invasive-candidiasis
#8
Murat Sütçü, Manolya Acar, Gonca Erköse Genç, İlknur Kökçü, Hacer Aktürk, Gürkan Atay, Selda Hançerli Törun, Nuran Salman, Zayre Erturan, Ayper Somer
AIM: Non-albicans Candida species and resistant microorganisms have been more commonly isolated in invasive candidiasis in recent years. The aim of this study was to evaluate the distrubution of Candida spp and antifungal resistance in our clinic. MATERIAL AND METHODS: Fifty-four Candida isolates and antifungal susceptibility results obtained from patients diagnosed as having invasive candidiasis between December 2012 and June 2016 were included. Clinical and laboratory data were retrospectively analyzed...
September 2017: Türk Pediatri Arşivi
https://www.readbyqxmd.com/read/29030835/a-new-technique-for-tension-free-reconstruction-in-large-incisional-hernia
#9
Gabriele Munegato, Landino Fei, Michele Schiano di Visconte, Danilo Da Ros, Luana Moras, Gabriele Bellio
In the surgical management of large incisional hernias, the main target is the closure of the abdominal wall defect on the midline without a dangerous increase in the intraabdominal pressure. In this setting, new intraperitoneal prosthesis and components separation techniques were proposed to solve this problem. Both solutions present some critical issues. A new surgical approach with a free lateral double layer prosthesis totally in polypropylene both sides (FLaPp®) is proposed to overcome this problem. This is a retrospective cohort analysis study with a prospectively collected database from two different Italian hospitals...
December 2017: Updates in Surgery
https://www.readbyqxmd.com/read/29017262/ceftolozane-tazobactam-for-the-treatment-of-multidrug-resistant-pseudomonas-aeruginosa-infections-clinical-effectiveness-and-evolution-of-resistance
#10
Ghady Haidar, Nathan J Philips, Ryan K Shields, Daniel Snyder, Shaoji Cheng, Brian A Potoski, Yohei Doi, Binghua Hao, Ellen G Press, Vaughn S Cooper, Cornelius J Clancy, M Hong Nguyen
Background: Data on the use of ceftolozane-tazobactam and emergence of ceftolozane-tazobactam resistance during multidrug resistant (MDR)-Pseudomonas aeruginosa infections are limited. Methods: We performed a retrospective study of 21 patients treated with ceftolozane-tazobactam for MDR-P. aeruginosa infections. Whole genome sequencing and quantitative real-time polymerase chain reaction were performed on longitudinal isolates. Results: Median age was 58 years; 9 patients (43%) were transplant recipients...
July 1, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28958281/an-innovative-way-to-separate-gastrointestinal-and-abdominal-wall-reconstruction-after-complex-abdominal-trauma
#11
David H Livingston, David V Feliciano
Despite advances in trauma care, a subset of patients surviving damage control cannot achieve fascial closure and require split-thickness skin grafting (STSG) of their open abdomen. Controversy exists as to whether reconstruction of the gastrointestine (GI) should be staged or performed at the time of abdominal wall reconstruction (AWR). Many surgeons do not believe that operations through the STSG can be completed safely or without loss of graft. This series reviews the outcomes of operations for GI reconstruction performed through the elevated healed STSG...
September 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/28916868/laparoscopic-liver-resection-using-a-monopolar-soft-coagulation-device-to-provide-maximum-intraoperative-bleeding-control-for-the-treatment-of-hepatocellular-carcinoma
#12
Mitsuo Miyazawa, Masayasu Aikawa, Katsuya Okada, Yukihiro Watanabe, Kojun Okamoto, Isamu Koyama
BACKGROUND: The popularity of laparoscopic liver resection (LLR) is spreading, worldwide, because the intraoperative blood loss is less than for open hepatectomy and it is associated with a shorter hospitalization period [1-6]. During LLR, intraoperative hemostasis is difficult to achieve, unlike during laparotomy where bleeding can be stopped instantly [7-10]. Our LLR method for the treatment of hepatocellular carcinoma (HCC) includes maximal control of intraoperative bleeding using a monopolar soft-coagulation device...
September 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28903171/-intraabdominal-infections
#13
Václava Adámková
Intraabdominal infections are the second most common cause of sepsis in intensive care units. Intraabdominal infections represent a wide variety of pathological conditions that involve lesions of all the intraabdominal organs. They also include intraperitoneal, retroperitoneal and parenchymal abscesses. The etiology of these infections usually includes organisms derived from the gut microbiota. The increasing rate of bacterial resistance is alarming. The treatment of intraabdominal infections is complex and involves source control and antibiotics...
June 2017: Klinická Mikrobiologie a Infekc̆ní Lékar̆ství
https://www.readbyqxmd.com/read/28847021/characterisation-and-safety-of-intraperitoneal-perioperative-administration-of-antibacterial-agents-a-systematic-review
#14
Siv Fonnes, Barbara Juliane Holzknecht, Magnus Arpi, Jacob Rosenberg
Background Intraperitoneal drug administration applies treatment at the site of diseases with gynaecological, urological, or gastrointestinal origin. The objective of this systematic review was to investigate perioperative intraperitoneal administration of antibacterial agents to characterise the drugs used and their safety profile. Methods A protocol was registered at PROSPERO (CRD42016038956). A systematic review was conducted and reported according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)...
August 28, 2017: Drug Research
https://www.readbyqxmd.com/read/28760356/unplanned-readmission-and-outpatient-examination-90-days-after-acute-appendectomy-in-adults
#15
Bo Bendvold, Arne Refsum, Line Schjøth-Iversen, Kjersti Bringedal, Anders Husby, Kristoffer Watten Brudvik
BACKGROUND: The aim of this study was to determine the frequency and indications for unplanned readmission and outpatient examination after acute appendectomy. METHODS: Adults who underwent acute appendectomy from 2008-2013 were included in the study and events occurring within 90-days from discharge recorded. RESULTS: A total of 710 patients underwent surgery. The appendix was removed in 622 patients and post-discharge contact occurred in 99 (15...
July 21, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28736715/a-case-of-liver-abscess-and-fusobacterium-septicemia
#16
Elham Rahmati, Rosemary C She, Brittany Kazmierski, P Jan Geiseler, Darren Wong
Fusobacterium species are well described as the causative pathogen in Lemierre's syndrome, a suppurative thrombophlebitis of the jugular vein. However, they are less recognized for a unique variant of Lemierre's syndrome presenting with invasive intraabdominal infection and associated portal vein thrombosis. We describe a case of Fusobacterium nucleatum with hepatic abscess and septic pylephlebitis.
2017: IDCases
https://www.readbyqxmd.com/read/28705666/in-vitro-activity-of-ceftolozane-tazobactam-against-pseudomonas-aeruginosa-and-enterobacteriaceae-isolates-recovered-from-hospitalized-patients-in-germany
#17
Harald Seifert, Barbara Körber-Irrgang, Michael Kresken
To evaluate the activity of ceftolozane/tazobactam in comparison with other broad-spectrum antimicrobials against Pseudomonas aeruginosa and Enterobacteriaceae, 497 non-duplicate P. aeruginosa and 802 Enterobacteriaceae clinical isolates were consecutively collected during the period from September 2014 to April 2015 from patients in Germany with bloodstream, lower respiratory tract, intraabdominal or urinary tract infections. Antimicrobial susceptibility testing was performed by broth microdilution. Results were interpreted according to EUCAST criteria...
July 10, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28694230/pharmacokinetics-of-piperacillin-tazobactam-in-plasma-peritoneal-fluid-and-peritoneum-of-surgery-patients-and-dosing-considerations-based-on-site-specific-pharmacodynamic-target-attainment
#18
Naoki Murao, Hiroki Ohge, Kazuro Ikawa, Yusuke Watadani, Shinnosuke Uegami, Norifumi Shigemoto, Norimitsu Shimada, Raita Yano, Toshiki Kajihara, Kenichiro Uemura, Yoshiaki Murakami, Norifumi Morikawa, Taijiro Sueda
Piperacillin-tazobactam (PIP-TAZ) is commonly used to treat intraabdominal infections; however, its penetration into abdominal sites is unclear. A pharmacokinetic analysis of plasma, peritoneal fluid, and peritoneum drug concentrations was conducted to simulate dosing regimens needed to attain the pharmacodynamic target in abdominal sites. PIP-TAZ (4 g-0.5 g) was intravenously administered to 10 patients before abdominal surgery for inflammatory bowel disease. Blood, peritoneal fluid, and peritoneum samples were obtained at the end of infusion (0...
September 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28651474/epidemiology-and-changes-in-mortality-of-sepsis-after-the-implementation-of-surviving-sepsis-campaign-guidelines
#19
Rubén Herrán-Monge, Arturo Muriel-Bombín, Marta M García-García, Pedro A Merino-García, Miguel Martínez-Barrios, David Andaluz, Juan Carlos Ballesteros, Ana María Domínguez-Berrot, Susana Moradillo-Gonzalez, Santiago Macías, Braulio Álvarez-Martínez, M José Fernández-Calavia, Concepción Tarancón, Jesús Villar, Jesús Blanco
PURPOSE: To determine the epidemiology and outcome of severe sepsis and septic shock after 9 years of the implementation of the Surviving Sepsis Campaign (SSC) and to build a mortality prediction model. METHODS: This is a prospective, multicenter, observational study performed during a 5-month period in 2011 in a network of 11 intensive care units (ICUs). We compared our findings with those obtained in the same ICUs in a study conducted in 2002. RESULTS: The current cohort included 262 episodes of severe sepsis and/or septic shock, and the 2002 cohort included 324...
January 1, 2017: Journal of Intensive Care Medicine
https://www.readbyqxmd.com/read/28642818/nivolumab-as-salvage-treatment-in-a-patient-with-hiv-related-relapsed-refractory-hodgkin-lymphoma-and-liver-failure-with-encephalopathy
#20
Jose D Sandoval-Sus, Francis Mogollon-Duffo, Ankita Patel, Nathan Visweshwar, Damian A Laber, Richard Kim, Michael V Jagal
BACKGROUND: We report the first case to our knowledge of a patient with relapsed/refractory classical hodgkin lymphoma and liver failure with encephalopathy along with human immunodeficiency virus/acquired immunodeficiency syndrome infection, successfully treated with nivolumab without major side effects and encouraging prolonged disease control. CASE PRESENTATION: In December 2015, at the time of the patient's progression from his Hodgkin lymphoma after fourth line treatment, he developed persistent fevers, abdominal distension, jaundice and worsening of his liver function tests...
2017: Journal for Immunotherapy of Cancer
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