keyword
MENU ▼
Read by QxMD icon Read
search

CRP

keyword
https://www.readbyqxmd.com/read/29353263/subcutaneous-adipose-tissue-biology-in-metabolic-syndrome
#1
REVIEW
Ishwarlal Jialal, Sridevi Devaraj
Metabolic syndrome (MetS) is a common global problem that comprises the cardio-metabolic cluster and predisposes to both diabetes and cardiovascular diseases. Although the pathogenic mechanisms have not been elucidated, both increased inflammation and insulin resistance play a pivotal role. It appears that both monocyte/macrophages and adipose tissue (AT) conspire to accentuate both the pro-inflammatory state and increased insulin resistance. Whilst there are scant data on visceral adipose tissue (VAT) and epicardial adipose tissue (EAT) biology, there are data on subcutaneous adipose tissue (SAT) dysregulation...
January 20, 2018: Hormone Molecular Biology and Clinical Investigation
https://www.readbyqxmd.com/read/29353098/the-anti-inflammatory-effects-of-statins-on-patients-with-rheumatoid-arthritis-a-systemic-review-and-meta-analysis-of-15-randomized-controlled-trials
#2
REVIEW
Guo-Min Li, Jie Zhao, Bing Li, Xiao-Fei Zhang, Jian-Xiong Ma, Xin-Long Ma, Jun Liu
BACKGROUND: Over the past several years, numerous studies investigated the anti-inflammatory effects of statin on patients with RA. However, the findings of the individual studies were often inconsistent or conflicting. MATERIALS AND METHODS: The Pubmed, Web of Science, Embase, Cochrane Library and CNKI literature databases were searched in order to identify randomized controlled clinical trials where the association between the anti-inflammatory effect of statin and RA was investigated...
January 15, 2018: Autoimmunity Reviews
https://www.readbyqxmd.com/read/29352846/the-janus-kinase-inhibitor-tofacitinib-inhibits-tnf-%C3%AE-induced-gliostatin-expression-in-rheumatoid-fibroblast-like-synoviocytes
#3
Yohei Kawaguchi, Yuko Waguri-Nagaya, Naoe Tatematsu, Yusuke Oguri, Masaaki Kobayashi, Masahiro Nozaki, Kiyofumi Asai, Mineyoshi Aoyama, Takanobu Otsuka
OBJECTIVES: Gliostatin (GLS) is known to have angiogenic and arthritogenic activity, and GLS expression levels in serum from patients with rheumatoid arthritis (RA) are significantly correlated with the disease activity. Tofacitinib is a novel oral Janus kinase (JAK) inhibitor and is effective in treating RA. However, the mechanism of action of tofacitinib in fibroblast-like synoviocytes (FLSs) has not been elucidated. The purpose of this study was to investigate the modulatory effects of tofacitinib on serum GLS levels in patients with RA and GLS production in FLSs derived from patients with RA...
January 15, 2018: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/29352395/association-between-crp-genetic-diversity-and-bipolar-disorder-comorbid-complications
#4
Wahid Boukouaci, José Oliveira, Bruno Etain, Meriem Bennabi, Christina Mariaselvam, Nora Hamdani, Céline Manier, Djaouida Bengoufa, Frank Bellivier, Chantal Henry, Jean-Pierre Kahn, Dominique Charron, Rajagopal Krishnamoorthy, Marion Leboyer, Ryad Tamouza
BACKGROUND: Chronic low-grade inflammation is believed to contribute, at least in a subset of patients, to the development of bipolar disorder (BD). In this context, the most investigated biological marker is the acute phase response molecule, C-reactive protein (CRP). While the genetic diversity of CRP was amply studied in various pathological settings, little is known in BD. METHODS: 568 BD patients along with 163 healthy controls (HC) were genotyped for the following single-nucleotide polymorphisms (SNPs) on the CRP gene: intron rs1417938 (+ 29) T/A, 3'-UTR rs1130864 (+ 1444) G/A, and downstream rs1205 (+ 1846) (C/T)...
January 20, 2018: International Journal of Bipolar Disorders
https://www.readbyqxmd.com/read/29351749/meta-analysis-of-serum-c-reactive-protein-and-cartilage-oligomeric-matrix-protein-levels-as-biomarkers-for-clinical-knee-osteoarthritis
#5
Junfeng Zhang
BACKGROUND: The roles of C-reactive protein (CRP) and cartilage oligomeric matrix protein (COMP) in knee osteoarthritis (KOA) remain controversial, thus the present study is aimed to explore the relationships between CRP, COMP, and the incidence/progression of KOA. METHODS: A systematic search was conducted on PubMed and Embase until September, 2016 for all the relevant studies. The pooled mean difference (MD) with its 95% confidence interval (95% CI) based on fixed effects model or random effects model was calculated to assess the potential role of CRP and COMP in the incidence or progression of KOA...
January 19, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29350418/species-differences-in-circulation-and-inflammatory-responses-in-children-with-common-respiratory-adenovirus-infections
#6
Haruna Nakamura, Takao Fujisawa, Shigeru Suga, Kiyosu Taniguchi, Mizuho Nagao, Masahiro Ito, Hitoshi Ochiai, Masami Konagaya, Nozomu Hanaoka, Tsuguto Fujimoto
BACKGROUND: Human adenoviruses (HAdVs) cause severe inflammatory respiratory infections, but previous epidemiological studies lacked analysis of the characteristics of the inflammation. METHODS: Consecutive patients <13 years old with acute febrile illness during a 2-year period were tested. HAdV strains were isolated from nasopharyngeal swabs, and molecular identification was performed by hexon, fiber and species-specific PCR methods. Blood inflammatory markers, including the white blood cell (WBC) count, CRP and 29 cytokines, were measured...
January 19, 2018: Journal of Medical Virology
https://www.readbyqxmd.com/read/29350279/evaluation-of-the-convergent-validity-of-an-estimated-cardiorespiratory-fitness-algorithm
#7
Paul D Loprinzi, Meghan K Edwards, Ovuokerie Addoh, John P Bentley
PURPOSE: Examine the convergent validity of a cardiorespiratory fitness (CRF) algorithm when compared to treadmill-assessed CRF. METHODS: Data from the 1999-2004 NHANES were used (N = 3259 adults 20-49 years). Cardiorespiratory fitness was estimated from an algorithm. Participants completed a submaximal treadmill-based protocol. We (1) evaluated the pairwise association (and ICC) between estimated and measured cardiorespiratory fitness, (2) employed a paired samples t test to examine potential mean differences between estimated and measured cardiorespiratory fitness, (3) constructed a Bland-Altman plot and 95% limits of agreement (LoA) to explore systematic differences and random error between estimated and measured cardiorespiratory fitness, and (4) examined the association (via linear regression) of estimated and measured cardiorespiratory fitness with chronic disease prevalence and C-reactive protein (CRP)...
January 19, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29350004/-posterior-debridement-and-bone-grafting-via-intervertebral-space-combined-with-internal-fixation-for-the-treatment-of-lumbosacral-tuberculosis
#8
Wei-Wei Li, Jun Liu, Liang Duan, Da-Peng Duan, Wen-Bo Wei, Ya-Yi Fan
OBJECTIVE: To explore the clinical effects of posterior debridement, bone grafting via intervertebral space combined with internal fixation for the treatment of lumbosacral tuberculosis. METHODS: The clinical data of 32 patients with lumbosacral tuberculosis underwent the procedure of one-stage posterior intervertebral debridement, bone grafting and internal fixation from January 2007 to July 2013 were retrospectively analyzed. There were 17 males and 15 females, aged from 27 to 63 years with an average of (49...
February 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29349976/-analysis-on-the-arthroscopy-efficacy-with-different-irrigation-times-for-the-treatment-of-suppurative-knee-arthritis-in-elder-patients
#9
Yi Yuan, Hai-Jun Zhang, Bo Zhang, Hao Luo, Chao Yang
OBJECTIVE: To evaluate the curative effect of arthroscopy-assisted irrigation with different times for the treatment of suppurative knee arthritis in elder patients. METHODS: From October 2012 to October 2014, 23 old patients with suppurative knee arthritis were treated with arthroscopic debridement and continuous irrigation. All the patients were randomly divided into two groups:one-week irrigation group (10 cases) and two-week irrigation group(13 cases). The ESR, CRP, recovery time of knee skin temperature, joint rang of motion and knee function were observed to evaluate the therapeutic effects...
April 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
https://www.readbyqxmd.com/read/29349839/inflammatory-biomarkers-and-intellectual-disability-in-patients-with-down-syndrome
#10
S Manti, M C Cutrupi, C Cuppari, E Ferro, V Dipasquale, G Di Rosa, R Chimenz, M A La Rosa, A Valenti, V Salpietro
BACKGROUND: Intellectual disability (ID) is part of the Down syndrome (DS) phenotypic spectrum, but the exact molecular pathophysiology of ID in individuals with DS is not yet fully understood, with many research hypotheses still unproven. Basing on previous studies (which suggested a possible role of altered inflammatory response in DS-related ID), we assessed the serum levels of a number of inflammatory biomarkers [serum amyloid A (SAA), C-reactive protein (C-RP), high mobility group box-1 (HMGB1)] in a cohort of individuals with DS and healthy controls...
January 19, 2018: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/29349642/increased-serum-periostin-concentrations-are-associated-with-the-presence-of-diabetic-retinopathy-in-patients-with-type-2-diabetes-mellitus
#11
Y Ding, Q Ge, H Qu, Z Feng, J Long, Q Wei, Q Zhou, R Wu, L Yao, H Deng
PURPOSE: To determine the association between serum periostin and the presence of diabetic retinopathy (DR). METHODS: Serum periostin was detected in 114 healthy subjects, 122 patients with type 2 diabetes mellitus (T2DM) and 159 patients with DR and compared among groups. Clinical data and other laboratory measurements such as glycated hemoglobin (HbA1c), lipid profiles, serum creatinine (Cr) and high-sensitivity CRP (hsCRP) were also collected and compared among groups...
January 18, 2018: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/29348903/the-systemic-inflammation-based-glasgow-prognostic-score-as-a-powerful-prognostic-factor-in-patients-with-upper-tract-urothelial-carcinoma
#12
Teruo Inamoto, Hideyasu Matsuyama, Shigeru Sakano, Naokazu Ibuki, Kiyoshi Takahara, Kazumasa Komura, Tomoaki Takai, Takuya Tsujino, Yuki Yoshikawa, Koichiro Minami, Kazuhiro Nagao, Ryo Inoue, Haruhito Azuma
Introduction and Objective: The combination of C-reactive protein and albumin, the Glasgow Prognostic Score (GPS), had independent prognostic value in patients with varying cancers, except for upper tract urothelial carcinoma (UTUC). The aim of this study was to describe the relationship between GPS and survival in patients with UTUC after adjustment for other prognostic factors. Materials and Methods: We queried 2 UTUC databases. Retrospective clinical series on patients with localized UTUC managed by nephroureterectomy with bladder cuff, for whom data from the Yamaguchi Uro-Oncology Group and Osaka Medical College registry, including age, presence of bladder cancer, pT stage, lymphovascular invasion, C-reactive protein (CRP) and albumin, were analyzed...
December 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/29348672/soluble-lrp1-is-an-independent-biomarker-of-epicardial-fat-volume-in-patients-with-type-1-diabetes-mellitus
#13
David de Gonzalo-Calvo, Cristina Colom, David Vilades, Andrea Rivas-Urbina, Abdel-Hakim Moustafa, Montserrat Pérez-Cuellar, Jose Luis Sánchez-Quesada, Antonio Pérez, Vicenta LLorente-Cortes
Epicardial adipose tissue (EAT) is a metabolically active tissue intimately associated with metabolic syndrome and cardiovascular disease. Quantification of EAT volume is an interesting clinical tool for the evaluation of cardiometabolic disease. Nevertheless, current methodology presents serious disadvantages. The soluble form of the receptor LRP1 (sLRP1) is a non-invasive biomarker of EAT in general population. Here, we analysed the potential of circulating sLRP1 as biomarker of EAT volume in patients with type 1 diabetes mellitus (T1DM)...
January 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29347936/comparative-analysis-of-copd-associated-with-tobacco-smoking-biomass-smoke-exposure-or-both
#14
Jordi Olloquequi, Sergio Jaime, Viviana Parra, Elizabeth Cornejo-Córdova, Gonzalo Valdivia, Àlvar Agustí, Rafael Silva O
BACKGROUND: Exposure to noxious gases and particles contained in both tobacco smoking (TS) and biomass smoke (BS) are well recognized environmental risk factors for chronic obstructive pulmonary disease (COPD). COPD is characterized by an abnormal inflammatory response, both in the pulmonary and systemic compartments. The differential effects of TS, BS or their combined exposure have not been well characterized yet. This study sought to compare the lung function characteristics and systemic inflammatory response in COPD patients exposed to TS, BS or their combination...
January 18, 2018: Respiratory Research
https://www.readbyqxmd.com/read/29346655/does-the-additional-component-of-calf-circumference-refine-metabolic-syndrome-in-correlating-with-cardiovascular-risk
#15
Chen-Jung Wu, Tung-Wei Kao, Yaw-Wen Chang, Tao-Chun Peng, Li-Wei Wu, Hui-Fang Yang, Wei-Liang Chen
Context: Calf circumference (CC) was a useful anthropometric tool, but there was limited study on the effect of CC on metabolic syndrome (MetS) for cardiovascular risk. Objective: The objective of our study was to determine whether additional component of CC refined MetS in correlating with cardiovascular, all-cause and cancer mortality. Design, Setting, Patients, and Interventions: From the 1999-2002 NHANES dataset, we analyzed four types of MetS: WaistMetS (increased waist circumference and ≥ two of four MetS components), CalfMetS (decreased CC and ≥ two of four MetS components), WCRMetS (increased waist-to-calf ratio and ≥ two of four MetS components), and CC plus MetS (decreased CC and ≥ three of five MetS components)...
January 15, 2018: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29346649/endothelial-function-in-rheumatoid-arthritis
#16
Mohammad Adawi, Abdulla Watad, Nicola Luigi Bragazzi, Howard Amital, Saaida Golan, Sirchan Rizak, Blum Arnon
Background: Rheumatoid arthritis (RA) patients are at higher risk of accelerated atherosclerosis. We sought to assess endothelial dysfunction in RA to find a possible mechanistic pathway that will explain this clinical phenomenon. Methods: A prospective study recruited 44 RA patients with an active long standing (>12 months) disease. All underwent a detailed assessment of disease activity. To estimate the endothelial function the Brachial Artery Method was performed, measuring flow mediated diameter percent change (FMD%)...
January 15, 2018: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29346621/assessing-polymyalgia-rheumatica-activity-when-c-reactive-protein-is-unavailable-or-uninterpretable
#17
Valérie Devauchelle-Pensec, Lea Saraux, Jean Marie Berthelot, Michel De Bandt, Divi Cornec, Dewi Guellec, Thierry Marhadour, Sandrine Jousse-Joulin, Maelenn Gouillou, Alain Saraux
Objective: The PMR activity score (PMR-AS) includes the CRP value, which may be lacking or invalid owing to anti-IL-6 therapy. Our objective was to develop alternatives to PMR-AS that do not require CRP. Methods: We used the Club Rhumatisme et Inflammation (CRI; 89 patients with PMR) and the Tolerance and Efficacy of tocilizumab iN pOlymyalgia Rheumatica (TENOR; 20 patients with recent-onset PMR naive to glucocorticoid who received three tocilizumab infusions, at weeks 0, 4 and 8, followed by prednisone from weeks 12 to 24) cohorts...
January 15, 2018: Rheumatology
https://www.readbyqxmd.com/read/29344688/inflammation-based-prognostic-score-predicts-postoperative-survival-of-patients-with-interstitial-pneumonia-after-undergoing-lung-cancer-resection
#18
Satoru Kobayashi, Yuji Matsumura, Yoko Karube, Morimichi Nishihira, Takashi Inoue, Osamu Araki, Sumiko Maeda, Masayuki Chida
OBJECTIVES: Idiopathic interstitial pneumonias (IIPs) are associated with an increased risk of lung cancer. Glasgow prognostic score (GPS), which uses serum C-reactive protein (CRP) and albumin levels to indicate systemic inflammatory response and nutrition level, has been reported to be a predictor of overall survival in patients with various types of cancer. We evaluated the usefulness of GPS for prediction of survival of patients with both lung cancer and IIPs following a lung resection procedure...
January 17, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29344528/psychometric-characteristics-of-clinical-reasoning-problems-crps-and-its-correlation-with-routine-multiple-choice-question-mcq-in-cardiology-department
#19
Zahra Derakhshandeh, Mitra Amini, Javad Kojuri, Marziyeh Dehbozorgian
Introduction: Clinical reasoning is one of the most important skills in the process of training a medical student to become an efficient physician. Assessment of the reasoning skills in a medical school program is important to direct students' learning. One of the tests for measuring the clinical reasoning ability is Clinical Reasoning Problems (CRPs). The major aim of this study is to measure psychometric qualities of CRPs and define correlation between this test and routine MCQ in cardiology department of Shiraz medical school...
January 2018: Journal of Advances in Medical Education & Professionalism
https://www.readbyqxmd.com/read/29344182/c-reactive-protein-albumin-and-neutrophil-lymphocyte-ratios-and-their-combination-predict-overall-survival-in-patients-with-gastric-cancer
#20
Minjie Mao, Xiaoli Wei, Hui Sheng, Peidong Chi, Yijun Liu, Xiaoyan Huang, Yifan Xiang, Qianying Zhu, Shan Xing, Wanli Liu
Multiple studies have reported the prognostic association of certain inflammatory factors with various types of cancer. The present study assessed the prognostic value of the C-reactive protein (CRP)/albumin (Alb) ratio and the neutrophil/lymphocyte ratio (NLR), separately and in combination, in gastric cancer (GC). A total of 337 cases pathologically diagnosed with gastric adenocarcinoma were retrospectively evaluated. The clinicopathological and prognostic relevance of the CRP/Alb ratio and NLR and their combination were analyzed...
December 2017: Oncology Letters
keyword
keyword
3186
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"