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https://www.readbyqxmd.com/read/29413183/editorial-commentary-is-arthroscopic-bone-grafting-nearly-equivalent-to-open-bone-grafting-for-glenoid-bone-defects-in-recurrent-anterior-shoulder-instability
#1
EDITORIAL
Matthew T Provencher
Arthroscopic techniques are an emerging technology to deal with glenoid bone defects in patients with anterior shoulder instability, and improvements are being made to safely minimize the risk of injury to the anterior neurovascular structures including the axillary nerve. Arthroscopic glenoid reconstruction is a technically demanding procedure, but it does have promising short-term outcomes. I truly like the concept of anterior (and also posterior) bone grafting for defects of the glenoid, including the arthroscopic Latarjet...
February 2018: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/29399459/opening-wedge-high-tibial-osteotomy-and-anterior-cruciate-ligament-reconstruction-or-revision
#2
Davide Edoardo Bonasia, Federico Dettoni, Anna Palazzolo, Roberto Rossi
High tibial osteotomy (HTO) is a valid treatment option for young active patients with medial tibiofemoral osteoarthrosis (OA) and varus deformity. Sometimes medial OA is combined with symptomatic anterior cruciate ligament (ACL) deficiency. Although isolated HTO (with possible delayed ACL reconstruction) might be indicated in the older population, young active patients may require combined HTO and ACL reconstruction. In addition, an abnormally increased tibial slope may predispose to ACL reconstruction failure and should be addressed for a successful ACL revision...
October 2017: Arthroscopy Techniques
https://www.readbyqxmd.com/read/29383503/a-prospective-randomized-trial-of-total-synovectomy-versus-limited-synovectomy-in-primary-total-knee-arthroplasty-evaluation-of-bleeding-postoperative-pain-and-quality-of-life-with-sf-12-v2
#3
Luis Dario Bernal-Fortich, Carlos Alberto Aguilar, Adrián H Rivera-Villa, Joel Galindo-Avalos, Pedro Aguilera-Martínez, Rubén Torres-González, Avelino Colin-Vázquez
BACKGROUND: During total knee arthroplasty (TKA), total synovectomy (TS) as a part of the surgical technique has been proposed to reduce the inflammatory tissue after the procedure, but there is a controversy about it because of the risk of major postsurgical bleeding. The aim of this study was to compare postoperative bleeding, pain, and health-related quality of life (HRQOL) after a TKA when a TS is performed and when it is not. METHODS: The difference in pre and postoperative hemoglobin was measured, as well as postoperative pain using visual analogue scale (VAS) scores at 24 and 48 h post-surgical, HRQOL was measured prior to surgery and at one year using the SF-12V2 questionnaire...
January 30, 2018: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29318349/-imaging-diagnostics-of-the-foot-what-the-orthopaedic-surgeon-expects-from-the-radiologist
#4
REVIEW
C Putz, S Hagmann, T Dreher
CLINICAL/METHODICAL ISSUE: Foot pain is in the case of long-term congenital, acquired or posttraumatic foot deformities a relevant clinical problem. STANDARD RADIOLOGICAL METHODS: On the basis of the clinical findings and the orthopaedic question, radiographs of the foot while standing in two planes are supplemented by radiographs of the ankle in an anterior-posterior plane. The imaging diagnostics of the foot are based on the conventional X‑ray diagnostic workup and becomes even more precise and differentiated by the possibility of intersecting imaging procedures...
January 9, 2018: Der Radiologe
https://www.readbyqxmd.com/read/29233163/intra-articular-injection-of-expanded-autologous-bone-marrow-mesenchymal-cells-in-moderate-and-severe-knee-osteoarthritis-is-safe-a-phase-i-ii-study
#5
Mahasen Al-Najar, Hiba Khalil, Jihad Al-Ajlouni, Eman Al-Antary, Mohammad Hamdan, Reem Rahmeh, Dana Alhattab, Osama Samara, Mohamad Yasin, Amenah Al Abdullah, Esraa Al-Jabbari, Dima Hmaid, Hanan Jafar, Abdalla Awidi
BACKGROUND: Knee osteoarthritis (KOA) is a major health problem especially in the aging population. There is a need for safe treatment that restores the cartilage and reduces the symptoms. The use of stem cells is emerging as a possible option for the moderate and severe cases. This study aimed at testing the safety of autologous bone marrow mesenchymal stem cells (BM-MSCs) expanded in vitro when given intra-articularly to patients with stage II and III KOA. As a secondary end point, the study tested the ability of these cells to relieve symptoms and restore the knee cartilage in these patients as judged by normalized knee injury and Osteoarthritis Outcome Score (KOOS) and by magnetic resonance imaging (MRI)...
December 12, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29227259/hypothyroidism-a-special-comorbidity-factor-in-patients-with-osteoarthrosis-clinical-pathophysiological-and-prognostic-aspects
#6
L Voloshyna, О Doholich, I Sithinska
Objective - to study the features of the functional and morphological condition of the thyroid gland (TG) in patients with osteoarthrosis (OA), the incidence and forms of hypothyroidism and their effects on clinical manifestations, metabolic disorders and the results of the treatment of OA and comorbid processes. A complex examination involved 312 patients with OA aged 37-76 years. Methods used: anthropometric, clinical, ultrasonographic, biochemical, radioimmunological (levels of TSH, free thyroxine, antibodies to thyroid peroxidase)...
November 2017: Georgian Medical News
https://www.readbyqxmd.com/read/29217163/cx3cr1-regulates-osteoarthrosis-chondrocyte-proliferation-and-apoptosis-via-wnt-%C3%AE-catenin-signaling
#7
You Sun, Feifei Wang, Xuehui Sun, Xiaoxue Wang, Lei Zhang, Yang Li
OBJECTIVE: The study was aimed to investigate the impact of CX3CR1 expression on the proliferation and apoptosis of osteoarthrosis (OA) chondrocytes through Wnt/ β-catenin pathway. METHODS: The expression levels of CX3CR1 and Wnt/β-catenin pathway-related genes mRNA and protein in OA chondrocytes were examined by qRT-PCR and western blot. MTT and flow cytometry (FCM) assays were employed to assess cell proliferation, cell cycle and apoptosis. XAV-939, a Wnt/β-catenin pathway inhibitor, was used to inhibit the pathway...
December 4, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/29186097/-the-experience-of-the-using-tolperisone-in-a-complex-conservative-therapy-of-an-osteoarthrosis-of-a-hip-joint
#8
O A Kaplunov, K O Kaplunov, E U Nekrasov
AIM: The comparison of the efficiency of the standard scheme of a conservative medicinal therapy of an OA of a hip joint and the modified scheme (with the muscle relaxant of the central action - Tolperisone) was the research objective. MATERIAL AND METHODS: The prospective research of the complex conservative therapy of two pools of patients with initial stages of a coxarthrosis from 2014 for 2017 with the subject assessment articulary treatment components is conducted...
2017: Khirurgiia
https://www.readbyqxmd.com/read/29162237/inter-individual-gene-variants-associated-with-trabecular-bone-plasticity-a-step-forward-in-the-personal-genomics-of-degenerative-bone-disease
#9
Enrique Caso, Cristina C Sabiers, Daniel López-Guillén, Jaime Caso, Manuel Toledano, Raquel Osorio, Estrella Osorio, Carmen Lozano, Enrique Guerado
Continuing tissue destruction in osteoarthrosis is maintained by molecular pathways related to an unbalanced chondrocyte metabolism, the loss of reactive oxygen species (ROS) homeostasis, increase catabolism in a degraded matrix and the limited response to growth factors due to cell aging. Rare deleterious gene variants driving relevant molecular pathways may play a key role in the pathogenesis and genetic control of common diseases and may also influence the common gene variants observed in GWAS. We use molecular profiling technologies based on massive sequencing of genes to interrogate clinical samples for a variety of molecules involved in the pathogenesis pathways of OA and also to derive new insights for drug targeting discovery at an early stage of the disease...
November 2017: Injury
https://www.readbyqxmd.com/read/29155310/legg-calv%C3%A3-perthes-disease
#10
REVIEW
J Leroux, S Abu Amara, J Lechevallier
Current knowledge of the causes and risk factors of Legg-Calvé-Perthesdisease (LCPD) does not allow effective preventive strategies. The outcome in adulthood is usually good. Hip osteoarthritis rarely develops before 50 years of age. The risk of osteoarthrosis depends chiefly on the final degree of joint incongruence. Age at onset and the lateral pillar classification are the two main outcome predictors and serve to guide the surgical indications based on the studies by Herring's group. Non-operative treatment is not effective...
November 16, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29115378/synovial-fluid%C3%A2-derived-synovial-fragments-represent-an-improved-source-of-synovial-mesenchymal-stem-cells-in-the-temporomandibular-joint
#11
Yu Yao, Zheng-Yu Li, Hong Zhang, You-Hua Zheng, Li-Xiang Mai, Wen-Jing Liu, Zhi-Guang Zhang, Yang-Peng Sun
Surgery-obtained synovium specimens (SSSs) can provide a source of synovial mesenchymal stem cells (SMSCs) for experimental studies. However, these specimens contain diverse tissues, including the intima and subintima; therefore, these SMSCs are not entirely derived from the intima and their cell source is heterogeneous. The present study isolated synovial fragments (SFs) from synovial fluid dilutions extracted from patients with temporomandibular joint (TMJ) osteoarthrosis. Unlike SSSs, SFs, which are membranous and translucent, consist of only several cell layers, indicating the presence of only the intima...
October 25, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29066098/brown-s%C3%A3-quard-syndrome-and-cervical-post-traumatic-subarachnoid-hematoma
#12
Fernando Rascón-Ramírez, Josué M Avecillas-Chasín, Albert Trondin, M Javier Arredondo
Cervical Traumatic SSH are very rare in literature. They are usually caused by cardiopulmonary diseases that increase vascular pressure causing spinal vessels rupture. In thoracolumbar spine, the spinal puncture is the most common cause. The ventrolateral position is even more unusual. In traumatic brain injury (TBI), an abrupt extension-flexion movement could have caused the rupture of subarachnoid vessels. This, accompanied by the slowed blood "wash out" (probably due to the previous osteoarthrosis and spinal canal stenosis), led to the formation of an organized clot, which caused an acute spinal cord compression syndrome...
October 20, 2017: Neurocirugía
https://www.readbyqxmd.com/read/29037894/indentation-mapping-revealed-poroelastic-but-not-viscoelastic-properties-spanning-native-zonal-articular-cartilage
#13
Joseph A Wahlquist, Frank W DelRio, Mark A Randolph, Aaron H Aziz, Chelsea M Heveran, Stephanie J Bryant, Corey P Neu, Virginia L Ferguson
Osteoarthrosis is a debilitating disease affecting millions, yet engineering materials for cartilage regeneration has proven difficult because of the complex microstructure of this tissue. Articular cartilage, like many biological tissues, produces a time-dependent response to mechanical load that is critical to cell's physiological function in part due to solid and fluid phase interactions and property variations across multiple length scales. Recreating the time-dependent strain and fluid flow may be critical for successfully engineering replacement tissues but thus far has largely been neglected...
December 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28979851/electron-probe-microanalysis-%C3%B0-f-experimentally-stimulated-osteoarthrosis-in-dogs
#14
Tatyana Stupina, Michael Shchudlo, Michael Stepanov
AIM: To develop methods of articular cartilage preparation for X-ray-electron probe microanalysis and to study its elements content in experimental osteoarthrosis. METHODS: Twenty dogs aged 2-8 years were divided in research (aged 2 years, induction of osteoarthrosis - IOA) and intact group. Intact group included three subgroups (aged 2, 5 and 8 years). Samples of cartilage after araldite saturation and pouring were partially cut into semithin sections stained with methylene blue and with methylene blue-basic fuchsin...
September 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28966039/temporomandibular-disorder-otologic-implications-and-its-relationship-to-sleep-bruxism
#15
Bruno Gama Magalhães, Jaciel Leandro de Melo Freitas, André Cavalcanti da Silva Barbosa, Maria Cecília Scheidegger Neves Gueiros, Simone Guimarães Farias Gomes, Aronita Rosenblatt, Arnaldo de França Caldas Júnior
INTRODUCTION: Temporomandibular disorder is an umbrella term for various clinical problems affecting the muscles of mastication, temporomandibular joint and associated structures. This disorder has a multifactor etiology, with oral parafunctional habits considered an important co-factor. Among such habits, sleep bruxism is considered a causal agent involved in the initiation and/or perpetuation of temporomandibular disorder. That condition can result in pain otologic symptoms. OBJECTIVE: The aim of the present study was to investigate the relationship between temporomandibular disorder and both otologic symptoms and bruxism...
August 23, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28920791/femoral-head-resection-in-two-livingstone-s-fruit-bats-pteropus-livingstonii
#16
Alberto Rodriguez Barbon, Peter Rushton-Taylor, Edward Bell, Andrew Routh
Two Livingstone's fruit bats (Pteropus livingstonii) presented with a unilateral partial paresis of the hind limbs. Radiographs revealed luxation of the coxofemoral joint and degenerative joint disease in the right coxofemoral joint in one case. The second case presented with recurrent luxation of the coxofemoral joint with osteoarthrosis of the femoral head. Clinical findings in both cases led to a decision to perform a femoral head resection. The performed surgery led to the recovery of normal function of the limb without any complications in both cases...
September 2017: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28913398/total-femur-arthroplasty-for-revision-hip-failure-in-osteogenesis-imperfecta-limits-of-biology
#17
Pablo Sanz-Ruiz, Manuel Villanueva-Martinez, Jose Antonio Calvo-Haro, Esther Carbó-Laso, Javier Vaquero-Martín
Osteogenesis imperfecta (OI) is a rare congenital disease characterized by alterations in bone quality, with susceptibility to fractures, instability, deformities, and osteoarthrosis. Prosthetic surgery in these patients is associated with an abnormally high rate of implant failures. On the other hand, abnormal bone fragility adds to the complexity of revision surgery in such individuals-thus representing a genuine challenge for the orthopaedic surgeon. We present a case of femoral reconstruction in a patient with OI and prosthetic loosening after reconstruction secondary to femoral septic pseudoarthrosis...
September 2017: Arthroplasty Today
https://www.readbyqxmd.com/read/28904969/sociodemographic-and-clinical-characteristics-of-centenarians-in-mexico-city
#18
Valdés-Corchado Pedro, Ruiz-Hernández Arturo, Pérez-Moreno Alejandro, Rosas-Carrasco Oscar
BACKGROUND: There is little evidence about the demography and health status of adults aged 100 years and over in Latin America and there are no studies in Mexico. OBJECTIVES: To describe the demographic characteristics and health status of centenarians residing in Mexico City. METHODS: This is a cross-sectional study using a population base of 393 community-dwelling centenarians in Mexico City. A comprehensive geriatric assessment was performed, including demographic information and health status...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28888229/changes-in-ankle-joint-motion-after-supramalleolar-osteotomy-a-cadaveric-model
#19
Hak Jun Kim, Eui Dong Yeo, Im Joo Rhyu, Soon-Hyuck Lee, Yeon Soo Lee, Young Koo Lee
BACKGROUND: Malalignment of the ankle joint has been found after trauma, by neurological disorders, genetic predisposition and other unidentified factors, and results in asymmetrical joint loading. For a medial open wedge supramalleolar osteotomy(SMO), there are some debates as to whether concurrent fibular osteotomy should be performed. We assessed the changes in motion of ankle joint and plantar pressure after supramalleolar osteotomy without fibular osteotomy. METHODS: Ten lower leg specimens below the knee were prepared from fresh-frozen human cadavers...
September 9, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28868088/chondral-defects-of-the-glenohumeral-joint-long-term-outcome-after-microfracturing-of-the-shoulder
#20
Sophia M Hünnebeck, Petra Magosch, Peter Habermeyer, Markus Loew, Sven Lichtenberg
INTRODUCTION: An increasing number of young patients are diagnosed with chondral lesions. Minimally invasive surgical techniques are important in order to delay progression of the early stages of osteoarthritis and the need for total joint replacement. MATERIALS AND METHODS: Patients (n = 32) who had received microfracturing of the shoulder were retrospectively enrolled, of whom 5 had received shoulder replacements after a mean time of 47 months. Of these patients, 23 completed the Disabilities of the Arm, Shoulder and Hand (DASH) and Constant-Murley Scores in addition to an additional subjective questionnaire...
2017: Obere Extremität
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