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Micronutrient deficiency

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https://www.readbyqxmd.com/read/28645724/micronutrient-deficiencies-and-the-human-gut-microbiota
#1
Núria Mach, Allison Clark
Little is known about how micronutrient deficiencies affect the human gut microbiota. A study by Hibberd et al. illustrates how these deficiencies affect the composition and function of gut microbiota, and further, how different species realize changes in gene expression and cellular metabolism to cope with micronutrient shortages.
June 20, 2017: Trends in Microbiology
https://www.readbyqxmd.com/read/28642774/increasing-provasculature-complexity-in-the-arabidopsis-embryo-may-increase-total-iron-content-in-seeds-a-hypothesis
#2
Hannetz Roschzttardtz, Sofía Bustos, Maria F Coronas, Miguel A Ibeas, Susana Grant-Grant, Joaquín Vargas-Pérez
Anemia due to iron deficiency is a worldwide issue, affecting mainly children and women. Seed iron is a major source of this micronutrient for feeding, however, in most crops these levels are too low to meet daily needs. Thus, increasing iron allocation and its storage in seeds can represent an important step to enhance iron provision for humans and animals. Our knowledge on seed iron homeostasis is mainly based on studies performed in the model plant Arabidopsis thaliana, where iron accumulates in endodermis cells surrounding the embryo provasculature...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28641600/the-influence-of-food-consumption-and-socio-economic-factors-on-the-relationship-between-zinc-and-iron-intake-and-status-in-a-healthy-population
#3
Marija Knez, Marina Nikolic, Milica Zekovic, James Cr Stangoulis, Mirjana Gurinovic, Maria Glibetic
OBJECTIVE: To examine Zn and Fe nutritional status of a healthy population by means of anthropometric, dietary and biochemical measurements and to investigate the relationship of usual Zn and Fe dietary intakes to Zn and Fe status. In addition, to examine the impact of food choices and socio-economic factors on Fe and Zn dietary intakes and status with the aim to identify groups at risk of dietary deficiency and suggest factors that may influence the status of these nutrients. DESIGN: Food consumption was assessed by 24 h recall questionnaires...
June 23, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28639913/novel-roles-of-folic-acid-as-redox-regulator-modulation-of-reactive-oxygen-species-sinker-protein-expression-and-maintenance-of-mitochondrial-redox-homeostasis-on-hepatocellular-carcinoma
#4
Kun-Goung Lai, Chi-Fen Chen, Chun-Te Ho, Jun-Jen Liu, Tsan-Zon Liu, Chi-Liang Chern
We provide herein several lines of evidence to substantiate that folic acid (or folate) is a micronutrient capable of functioning as a novel redox regulator on hepatocellular carcinoma. First, we uncovered that folate deficiency could profoundly downregulate two prominent anti-apoptotic effectors including survivin and glucose-regulated protein-78. Silencing of either survivin or glucose-regulated protein-78 via small interfering RNA interfering technique established that both effectors could serve as reactive oxygen species sinker proteins...
June 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/28637710/the-combined-action-of-duplicated-boron-transporters-is-required-for-maize-growth-in-boron-deficient-conditions
#5
Mithu Chatterjee, Qiujie Liu, Caitlin Menello, Mary Galli, Andrea Gallavotti
The micronutrient boron is essential in maintaining the structure of plant cell walls and is critical for high yields in crop species. Boron can move into plants by diffusion or by active and facilitated transport mechanisms. We recently showed that mutations in the maize boron efflux transporter ROTTEN EAR (RTE) cause severe developmental defects and sterility. RTE is part of a small gene family containing five additional members (RTE2-RTE6) that show tissue specific expression. The close paralogous gene RTE2 encodes a protein with 95% amino acid identity with RTE and is similarly expressed in shoot and root cells surrounding the vasculature...
June 21, 2017: Genetics
https://www.readbyqxmd.com/read/28636832/nutrient-deficiencies-are-common-prior-to-bariatric-surgery
#6
Leigh A Frame-Peterson, Robin D Megill, Suzanne Carobrese, Michael Schweitzer
Obesity, defined as a body mass index >30 kg/m(2), is a growing worldwide epidemic currently effecting 1 in 10 adults, with rates as high as 40% in the United States. The only proven long-term treatment of severe obesity on a population level is surgical modification of the gastrointestinal anatomy to induce weight loss, termed bariatric surgery. With adequate physician guidance and appropriate candidate criteria, bariatric surgery is an option for effective long-term treatment of obesity and its related comorbidities...
June 1, 2017: Nutrition in Clinical Practice
https://www.readbyqxmd.com/read/28634484/manipulation-of-metabolic-pathways-to-develop-vitamin-enriched-crops-for-human-health
#7
REVIEW
Ling Jiang, Weixuan Wang, Tong Lian, Chunyi Zhang
Vitamin deficiencies are major forms of micronutrient deficiencies, and are associated with huge economic losses as well as severe physical and intellectual damages to humans. Much evidence has demonstrated that biofortification plays an important role in combating vitamin deficiencies due to its economical and effective delivery of nutrients to populations in need. Biofortification enables food plants to be enriched with vitamins through conventional breeding and/or biotechnology. Here, we focus on the progress in the manipulation of the vitamin metabolism, an essential part of biofortification, by the genetic modification or by the marker-assisted selection to understand mechanisms underlying metabolic improvement in food plants...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28631167/copper-and-ectopic-expression-of-the-arabidopsis-transport-protein-copt1-alter-iron-homeostasis-in-rice-oryza-sativa-l
#8
Amparo Andrés-Bordería, Fernando Andrés, Antoni Garcia-Molina, Ana Perea-García, Concha Domingo, Sergi Puig, Lola Peñarrubia
Copper deficiency and excess differentially affect iron homeostasis in rice and overexpression of the Arabidopsis high-affinity copper transporter COPT1 slightly increases endogenous iron concentration in rice grains. Higher plants have developed sophisticated mechanisms to efficiently acquire and use micronutrients such as copper and iron. However, the molecular mechanisms underlying the interaction between both metals remain poorly understood. In the present work, we study the effects produced on iron homeostasis by a wide range of copper concentrations in the growth media and by altered copper transport in Oryza sativa plants...
June 19, 2017: Plant Molecular Biology
https://www.readbyqxmd.com/read/28629485/characterisation-of-vitamin-and-mineral-supplement-users-differentiated-according-to-their-motives-for-using-supplements-results-of-the-german-national-nutrition-monitoring-nemonit
#9
Anne Frey, Ingrid Hoffmann, Thorsten Heuer
OBJECTIVE: To characterise German vitamin and mineral supplement users differentiated by their motives for supplement use. DESIGN: Data were obtained from the German National Nutrition Monitoring (2010/11) via two 24 h dietary recalls and a telephone interview. Motive-based subgroups of supplement users were identified by factor and cluster analysis. Sociodemographic, lifestyle, health and dietary characteristics and supplement use were examined. Differences were analysed using χ 2 tests, logistic and linear regression models...
June 20, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28629136/zinc-in-infection-and-inflammation
#10
REVIEW
Nour Zahi Gammoh, Lothar Rink
Micronutrient homeostasis is a key factor in maintaining a healthy immune system. Zinc is an essential micronutrient that is involved in the regulation of the innate and adaptive immune responses. The main cause of zinc deficiency is malnutrition. Zinc deficiency leads to cell-mediated immune dysfunctions among other manifestations. Consequently, such dysfunctions lead to a worse outcome in the response towards bacterial infection and sepsis. For instance, zinc is an essential component of the pathogen-eliminating signal transduction pathways leading to neutrophil extracellular traps (NET) formation, as well as inducing cell-mediated immunity over humoral immunity by regulating specific factors of differentiation...
June 17, 2017: Nutrients
https://www.readbyqxmd.com/read/28628394/nutritional-routine-of-tae-kwon-do-athletes-prior-to-competition-what-is-the-impact-of-weight-control-practices
#11
Sousana K Papadopoulou, Vasiliki A Dalatsi, Spyridon K Methenitis, Konstantinos G Feidantsis, Ioannis G Pagkalos, Maria Hassapidou
OBJECTIVE: The purpose of the present study was to investigate and assess the common dietary and weight management strategies of Tae Kwon Do (TKD) athletes prior to national competitions, as well as to examine the relationships between these strategies and body weight reduction and sensation of physical condition. METHODS: Sixty (n = 60) TKD athletes, 23 women (19.4 ± 2.9 years) and 37 men (20.4 ± 3.6 years), with at least 12.1 ± 3.1 years of experience, participated in the present study...
June 19, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28626899/consideration-of-the-presence-of-inflammation-is-essential-for-interpretation-of-serum-micronutrient-results
#12
Emma Osland
It was with great interest I read the recent contribution by Christie-David and Gunton, 'Vitamin C deficiency and diabetes mellitus - easily missed?' [1], outlining their retrospective cohort study in 11 patients with poorly healing foot ulcers in the setting of diabetes mellitus. Their findings suggest previously unrecognized vitamin C deficiency may have been a contributing factor to the ulcers that were being treated in their clinic; a hypothesis supported by the healing reported to occur within 3 weeks of the commencement of vitamin C replacement [1]...
June 19, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28626279/nutritional-status-of-foster-children-in-the-u-s-implications-for-cognitive-and-behavioral-development
#13
Ursula A Tooley, Zeina Makhoul, Philip A Fisher
OBJECTIVE: Children in foster care are at greater risk for poor health, physical, cognitive, behavioral, and developmental outcomes than are children in the general population. Considerable research links early nutrition to later cognitive and behavioral outcomes. The aim of this narrative review is to examine the prevalence of poor nutrition and its relation to subsequent health and development in foster children. METHOD: Relevant studies for inclusion were identified from numerous sources (e...
November 2016: Children and Youth Services Review
https://www.readbyqxmd.com/read/28622483/human-milk-fortifiers-do-not-meet-the-current-recommendation-for-nutrients-in-very-low-birth-weight-infants
#14
Winston Koo, Hilary Tice
BACKGROUND: Use of multinutrient fortifiers is standard of care for small preterm infants fed exclusively human milk. However, adequacy of human milk fortifiers (HMFs) to meet the recommended intake for macronutrients and micronutrients is now known. MATERIALS AND METHODS: Nutrient content of human milk fortified according to manufacturer's recommendations was compared at isocaloric levels for 1 human milk-based (HMF-A), 2 bovine milk protein-based (HMF-B, HMF-C), and 2 preterm infant formulas (PTF-B, PTF-C)...
June 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28620477/micronutrient-deficiencies-in-the-elderly-could-ready-meals-be-part-of-the-solution
#15
Richard Hoffman
Micronutrient deficiencies contribute to many age-related disorders. One group at particular risk of micronutrient deficiencies is the elderly. Many elderly, such as the frail and those living in institutions, rely on ready meals of variable, often poor, nutritional quality for a significant part of their daily nutritional needs. New policies are needed to ensure that micronutrients (vitamins and minerals) and phytochemicals of known nutritional value are retained during the manufacture of ready meals. This together with increased awareness of the importance of micronutrients for health, and simple, clear labelling of the micronutrient content of ready meals would help in the choice of healthier products...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/28615262/predictors-of-anemia-in-women-of-reproductive-age-biomarkers-reflecting-inflammation-and-nutritional-determinants-of-anemia-brinda-project
#16
REVIEW
James P Wirth, Bradley A Woodruff, Reina Engle-Stone, Sorrel Ml Namaste, Victor J Temple, Nicolai Petry, Barbara Macdonald, Parminder S Suchdev, Fabian Rohner, Grant J Aaron
Background: Anemia in women of reproductive age (WRA) (age range: 15-49 y) remains a public health problem globally, and reducing anemia in women by 50% by 2025 is a goal of the World Health Assembly.Objective: We assessed the associations between anemia and multiple proximal risk factors (e.g., iron and vitamin A deficiencies, inflammation, malaria, and body mass index) and distal risk factors (e.g., education status, household sanitation and hygiene, and urban or rural residence) in nonpregnant WRA.Design: Cross-sectional, nationally representative data from 10 surveys (n = 27,018) from the Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project were analyzed individually and pooled by the infection burden and risk in the country...
June 14, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28615260/predictors-of-anemia-in-preschool-children-biomarkers-reflecting-inflammation-and-nutritional-determinants-of-anemia-brinda-project
#17
REVIEW
Reina Engle-Stone, Grant J Aaron, Jin Huang, James P Wirth, Sorrel Ml Namaste, Anne M Williams, Janet M Peerson, Fabian Rohner, Ravi Varadhan, O Yaw Addo, Victor Temple, Pura Rayco-Solon, Barbara Macdonald, Parminder S Suchdev
Background: A lack of information on the etiology of anemia has hampered the design and monitoring of anemia-control efforts.Objective: We aimed to evaluate predictors of anemia in preschool children (PSC) (age range: 6-59 mo) by country and infection-burden category.Design: Cross-sectional data from 16 surveys (n = 29,293) from the Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project were analyzed separately and pooled by category of infection burden. We assessed relations between anemia (hemoglobin concentration <110 g/L) and severe anemia (hemoglobin concentration <70 g/L) and individual-level (age, anthropometric measures, micronutrient deficiencies, malaria, and inflammation) and household-level predictors; we also examined the proportion of anemia with concomitant iron deficiency (defined as an inflammation-adjusted ferritin concentration <12 μg/L)...
June 14, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28615256/adjusting-soluble-transferrin-receptor-concentrations-for-inflammation-biomarkers-reflecting-inflammation-and-nutritional-determinants-of-anemia-brinda-project
#18
REVIEW
Fabian Rohner, Sorrel Ml Namaste, Leila M Larson, O Yaw Addo, Zuguo Mei, Parminder S Suchdev, Anne M Williams, Fayrouz A Sakr Ashour, Rahul Rawat, Daniel J Raiten, Christine A Northrop-Clewes
Background: Iron deficiency is thought to be one of the most prevalent micronutrient deficiencies globally, but an accurate assessment in populations who are frequently exposed to infections is impeded by the inflammatory response, which causes iron-biomarker alterations.Objectives: We assessed the relation between soluble transferrin receptor (sTfR) concentrations and inflammation and malaria in preschool children (PSC) (age range: 6-59 mo) and women of reproductive age (WRA) (age range: 15-49 y) and investigated adjustment algorithms to account for these effects...
June 14, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28615254/methodologic-approach-for-the-biomarkers-reflecting-inflammation-and-nutritional-determinants-of-anemia-brinda-project
#19
REVIEW
Sorrel Ml Namaste, Grant J Aaron, Ravi Varadhan, Janet M Peerson, Parminder S Suchdev
Background: The Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project is a multiagency and multicountry collaboration that was formed to improve micronutrient assessment and to better characterize anemia.Objectives: The aims of the project were to 1) identify factors associated with inflammation, 2) assess the relations between inflammation, malaria infection, and biomarkers of iron and vitamin A status and compare adjustment approaches, and 3) assess risk factors for anemia in preschool children (PSC) and women of reproductive age (WRA)...
June 14, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28615252/research-policy-and-programmatic-considerations-from-the-biomarkers-reflecting-inflammation-and-nutritional-determinants-of-anemia-brinda-project
#20
REVIEW
Rebecca J Stoltzfus, Rolf Klemm
The Biomarkers Reflecting Inflammation and Nutritional Determinants of Anemia (BRINDA) project sought to inform the interpretation of iron and vitamin A biomarkers (ferritin, serum transferrin receptor, and retinol binding protein) in settings of prevalent inflammation as well as the prevention of and control strategies to address anemia. Our purpose is to comment on the contributions of the BRINDA to advance global knowledge with regard to iron and vitamin A status assessment in women and preschool children and to analyze the findings in terms of their rigor and usefulness for global nutrition research and programs...
June 14, 2017: American Journal of Clinical Nutrition
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