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https://www.readbyqxmd.com/read/28738534/high-expression-of-cd47-predicts-adverse-prognosis-in-chinese-patients-and-suppresses-immune-response-in-melanoma
#1
Wenhua Fu, Jisen Li, Wei Zhang, Peng Li
BACKGROUND: Cluster of differentiation 47 (CD47) negatively regulates macrophage phagocytosis and is correlated with adverse survival of multiple cancers. In melanoma patients, especially in Chinese melanoma patients, its prognostic value is unclear. In this study, we aim to study the prognostic value of CD47 in a Chinse melanoma patient cohort and its immunomodulation roles in mouse model. METHOD: 164 melanoma tissue specimens were collected. The expression of CD47 in these clinical samples was examined by immunohistochemistry staining (IHC)...
July 20, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28738473/-hoof-genotyping-characteristics-of-brucella-melitensis-strains-isolated-in-ulanqab-of-inner-mongolia-autonomous-region
#2
Z G Liu, M Wang, R H Liu, X J Shang, B Y Cui
Objective: To investigate the HOOF genotyping characteristics of 83 Brucella (B.) melitensis strains isolated in Ulanqab of Inner Mongolia Autonomous Region from 2012 to 2015. Methods: A total of 83 B. melitensis strains were detected by convention identification and AMOS-PCR, then HOOF protocol with eight VNTR locus were used for the genotyping of the strains, and the allelic diversity of each VNTR locus and the discriminatory power of VNTR typing of HOOF were assessed by Hunter-Gaston Discriminatory index...
July 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28738470/-prevalence-of-hypercholesterolemia-and-influence-factors-in-residents-aged-18-65-years-in-beijing
#3
B Jiang, A J Ma, H Li, K Fang, J Dong, J Xie, K Qi, C Xie, Y Zhou, Y Zhao, Z Dong
Objective: To understand the prevalence of hypercholesterolemia and related risk factors in residents aged 18-65 years in Beijing and provide scientific evidence for the prevention and control of hypercholesterolemia. Methods: The data were collected from Beijing Non-communicable and Chronic Disease Survey and stratified cluster sampling method was used to select study subjects, and questionnaire investigation, physical measurement and laboratory examination were conducted to collect information. Results: The prevalence of hypercholesterolemia and borderline hypercholesterolemia was 6...
July 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28738468/-analysis-on-spatial-distribution-of-tuberculosis-in-china-2012-2014
#4
J Fan, H X Rao, P Wu, J Zhang, Y P Wu, J H Pan, W H Li, L X Qiu
Objective: To analyze the spatial distribution of the incidence of tuberculosis (TB) in China from 2012 to 2014 and provide evidence for the prevention and control of TB. Methods: The database of TB in China from 2012 to 2014 was established by using geographical information system, the spatial distribution map was drawn, trend analysis and spatial autocorrelation analysis were conducted to explore the spatial distribution pattern of TB and identify hot areas. Results: The trend surface analysis showed that the incidence of TB decreased gradually from the west to the east in China, and the U type curve could reflect the TB distribution from the south to the north; Global spatial autocorrelation analysis showed the 2012-2014 global Moran's I were 0...
July 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28738463/-a-cross-sectional-study-on-dyslipidemia-in-migrants-in-inner-mongolia-autonomous-region
#5
T Zhang, Q Zhou, Y G Qian, J Zhou, S J Wu, P Y Wang, A P Liu
Objective: To investigate the prevalence of dyslipidemia in migrants in Inner Mongolia Autonomous Region. Methods: A stratified multi-stage cluster equal size sampling was performed among the migrants aged ≥18 years who were engaged in manufacturing, wholesale retail, accommodation and catering service, social service, construction and other and 1 501 migrants from five area in Inner Mongolia Autonomous Region was investigated by means of questionnaires survey, physical measurements and laboratory detection...
July 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28738461/-role-of-maternal-drug-use-and-environmental-exposure-during-pregnancy-and-delivery-pattern-in-allergic-infants-and-toddlers
#6
S Wang, H S Wang, J X Jiang, Y Wang, T Xu
Objective: To understand correlation between maternal drug use and environmental exposure during pregnancy and delivery pattern and allergy in infants and toddlers, and provide theoretical bases for the early prevention and intervention of infantile allergies. Methods: Case control study based on cross-sectional investigation was conducted. Thirty-three cities were selected in China. Randomly cluster sampling method was used to select a community in each city as the study sample, the women with infants aged 0-24 months were interviewed in the form of face-to-face questionnaire survey...
July 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28738457/-survey-of-economic-burden-of-hepatitis-b-related-diseases-in-12-areas-in-china
#7
Q S Ma, S Liang, H W Xiao, S X Zhang, G H Zhuang, Y H Zou, H Z Tan, J C Liu, Y H Zhang, A Q Xu, L Zhang, X X Feng, D S Hu, F Z Wang, F Q Cui, X F Liang
Objective: Less surveys on the economic burden of hepatitis B (HB)-related diseases have been conducted in China, so the socioeconomic harm caused by the diseases is not clear and the key parameters for economic evaluation of hepatitis B prevention and treatment are lacking. This study aimed to analyze the direct, indirect and intangible expenditures of hospitalized patients with HB-related diseases during hospitalization and during a year in different areas of China. Methods: The hospitals for infectious diseases and the large general hospitals in 12 areas in China were selected in the study...
July 10, 2017: Zhonghua Liu Xing Bing Xue za Zhi, Zhonghua Liuxingbingxue Zazhi
https://www.readbyqxmd.com/read/28738410/no-large-population-of-unbound-or-wide-orbit-jupiter-mass-planets
#8
Przemek Mróz, Andrzej Udalski, Jan Skowron, Radosław Poleski, Szymon Kozłowski, Michał K Szymański, Igor Soszyński, Łukasz Wyrzykowski, Paweł Pietrukowicz, Krzysztof Ulaczyk, Dorota Skowron, Michał Pawlak
Planet formation theories predict that some planets may be ejected from their parent systems as result of dynamical interactions and other processes. Unbound planets can also be formed through gravitational collapse, in a way similar to that in which stars form. A handful of free-floating planetary-mass objects have been discovered by infrared surveys of young stellar clusters and star-forming regions as well as wide-field surveys, but these studies are incomplete for objects below five Jupiter masses. Gravitational microlensing is the only method capable of exploring the entire population of free-floating planets down to Mars-mass objects, because the microlensing signal does not depend on the brightness of the lensing object...
July 24, 2017: Nature
https://www.readbyqxmd.com/read/28738348/colistin-resistance-in-kpc-2-and-shv-5-producing-klebsiella-pneumoniae-clinical-isolates-in-bulgaria
#9
Encho Savov, Iva Todorova, Lida Politi, Angelina Trifonova, Maja Borisova, Elena Kioseva, Athanassios Tsakris
BACKGROUND/AIMS: Colistin resistance is increasingly recognized among carbapenemase-producing Klebsiella pneumoniae isolates in several European regions. The current study documents the appearance of colistin resistance among KPC-2 and SHV-5-produning K. pneumoniae strains in Bulgaria. METHODS: Four colistin-resistant K. pneumoniae isolates were recovered from 2 patients hospitalized in the anesthesiology and resuscitation clinic of a tertiary care university hospital in Sofia, Bulgaria...
July 22, 2017: Chemotherapy
https://www.readbyqxmd.com/read/28738295/does-the-effect-of-one-day-simulation-team-training-in-obstetric-emergencies-decline-within-one-year-a-post-hoc-analysis-of-a-multicentre-cluster-randomised-controlled-trial
#10
J van de Ven, A F Fransen, E Schuit, P J van Runnard Heimel, B W Mol, S G Oei
Does the effect of one-day simulation team training in obstetric emergencies decline within one year? A post-hoc analysis of a multicentre cluster randomised controlled trial. J van de Ven, AF Fransen, E Schuit, PJ van Runnard Heimel, BW Mol, SG Oei OBJECTIVE: To investigate whether the effect of a one-day simulation-based obstetric team training on patient outcome changes over time. STUDY DESIGN: Post-hoc analysis of a multicentre, open, randomised controlled trial that evaluated team training in obstetrics (TOSTI study)...
July 14, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28738219/finding-features-figuratively
#11
Sarah H Solomon, Sharon L Thompson-Schill
Object concepts refer to unique clusters of properties that can be selectively activated or inhibited depending on what information is currently relevant. This conceptual "stretching" enables limitless new meanings to be generated, and figurative language provides a useful framework in which to study this conceptual flexibility. Here we probe the cognitive and neural mechanisms underlying the comprehension of novel metaphors as a means of understanding the conceptual flexibility inherent to language processing more generally...
July 21, 2017: Brain and Language
https://www.readbyqxmd.com/read/28738071/the-pit-trap-a-model-free-bootstrap-procedure-for-inference-about-regression-models-with-discrete-multivariate-responses
#12
David I Warton, Loïc Thibaut, Yi Alice Wang
Bootstrap methods are widely used in statistics, and bootstrapping of residuals can be especially useful in the regression context. However, difficulties are encountered extending residual resampling to regression settings where residuals are not identically distributed (thus not amenable to bootstrapping)-common examples including logistic or Poisson regression and generalizations to handle clustered or multivariate data, such as generalised estimating equations. We propose a bootstrap method based on probability integral transform (PIT-) residuals, which we call the PIT-trap, which assumes data come from some marginal distribution F of known parametric form...
2017: PloS One
https://www.readbyqxmd.com/read/28738062/analysis-of-novel-runx2-mutations-in-chinese-patients-with-cleidocranial-dysplasia
#13
Xianli Zhang, Yang Liu, Xiaozhe Wang, Xiangyu Sun, Chenying Zhang, Shuguo Zheng
Cleidocranial dysplasia (CCD) is an autosomal dominant inheritable skeletal disorder characterized by cranial dysplasia, clavicle hypoplasia and dental abnormalities. This disease is mainly caused by heterozygous mutations in RUNX2, a gene that encodes an osteoblast-specific transcription factor. In the present study, mutational analyses of RUNX2 gene were performed on four unrelated Chinese patients with CCD. Four different RUNX2 mutations were detected in these patients, including one nonsense mutation (c...
2017: PloS One
https://www.readbyqxmd.com/read/28738060/community-detection-in-sequence-similarity-networks-based-on-attribute-clustering
#14
Janamejaya Chowdhary, Frank E Löffler, Jeremy C Smith
Networks are powerful tools for the presentation and analysis of interactions in multi-component systems. A commonly studied mesoscopic feature of networks is their community structure, which arises from grouping together similar nodes into one community and dissimilar nodes into separate communities. Here, the community structure of protein sequence similarity networks is determined with a new method: Attribute Clustering Dependent Communities (ACDC). Sequence similarity has hitherto typically been quantified by the alignment score or its expectation value...
2017: PloS One
https://www.readbyqxmd.com/read/28738023/cluster-assembly-route-to-a-novel-octagonal-two-dimensional-zno-monolayer
#15
Prashant V Gaikwad, Pradeep K Pujari, Sudip Chakroborty, Anjali Kshirsagar
To explore the possibility of cluster assembly resulting in a two-dimensional (2D) stable monolayer of ZnO, a systematic study is performed on the structural evolution of bare and passivated stoichiometric clusters of [Formula: see text] [Formula: see text], [Formula: see text], using density-functional-theory-based first principles electronic structure calculations. The changes in hybridization are investigated with the aid of the site-projected partial density of states and partial charge density, while the effect of passivation and size on the ionicity of the cluster is studied using Bader charge analysis...
July 24, 2017: Journal of Physics. Condensed Matter: An Institute of Physics Journal
https://www.readbyqxmd.com/read/28737939/several-gd-m-heterometal-organic-frameworks-with-gdn-as-nodes-tunable-structures-and-magnetocaloric-effect
#16
Peng-Fei Shi, Chun-Shuai Cao, Chu-Ming Wang, Bin Zhao
Tunable structures and magnetocaloric effect (MCE) of seven MOFs with [Gdn] as nodes are explored. The [Gdn] node is realized from mononuclear [Gd] to binuclear paddle-wheel [Gd2], tetranuclear tetrahedral [Gd4], and pentanuclear trigonal bipyramidal [Gd5]. Meanwhile, the magnetic entropy changes from 19.4 to 46.0 J·kg(-1)·K(-1). The results reveal that the effect of magnetic density on MCE plays a dominant role for Gd(3+)-based compounds, and high spin ground state of Mn(2+) (S = 5/2) is more favorable to achieve high MCE than that with Zn(2+), Co(2+), and Ni(2+) (Co(2+), S = 3/2; Ni(2+), S = 1)...
July 24, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28737803/concerted-transfer-of-multiple-protons-in-acid-water-clusters-hcl-h2o-2-and-hf-h2o-4
#17
I Zakai, M E Varner, R B Gerber
Molecular dynamics simulations using directly ab initio potentials are carried out for the ionically bonded clusters [(Cl(-))(H3O(+))]2 and [(F(-))(H3O(+))]4 to explore their transitions to the hydrogen-bonded [(HCl)(H2O)]2 and [(HF)(H2O)]4 structures during the first picosecond of simulation. Both the ionic and the H-bonded structures that are formed are highly symmetric. It is found that proton transfers are concerted in all trajectories for [(Cl(-))(H3O(+))]2. For [(F(-))(H3O(+))]4, the fully concerted mechanism is dominant but partially concerted transfers of two or three protons at the same time also occur...
July 24, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28737802/accurate-prediction-of-energetic-properties-of-ionic-liquid-clusters-using-a-fragment-based-quantum-mechanical-method
#18
Jinfeng Liu, Xiao He
Accurate prediction of physicochemical properties of ionic liquids (ILs) is of great significance to understand and design novel ILs with unique properties. This study employed the electrostatically embedded generalized molecular fractionation (EE-GMF) method for accurate energy calculation of IL clusters. The accuracy and efficiency of the EE-GMF method are systematically assessed at different ab initio levels (including HF, DFT and MP2) with diverse basis sets. With the fixed charge model for the embedding field, the deviations of the EE-GMF approach from conventional full system calculations are within 2...
July 24, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28737797/cation-distribution-dependent-magnetic-properties-in-cocr2-xfexo4-x-0-1-to-0-5-exafs-m%C3%A3-ssbauer-and-magnetic-measurements
#19
D Kumar, A Banerjee, A Mahmoud, Chandana Rath
In this report, we have examined the evolution of the structure and rich magnetic transitions such as a paramagnetic to ferrimagnetic phase transition at the Curie temperature (TC), spiral ordering temperature (TS) and lock-in temperature (TL) observed in the CoCr2O4 spinel multiferroic after substituting Fe. The crystal structure, microstructure and cation distribution among the tetrahedral (A) and octahedral (B) sites in the spinel lattice are characterised by X-ray diffraction, transmission electron microscopy, Extended X-ray Absorption Fine Structure (EXAFS) and Mössbauer spectroscopy...
July 24, 2017: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/28737772/cortical-forces-and-cdc-42-control-clustering-of-par%C3%A2-proteins-for-caenorhabditis-elegans-embryonic%C3%A2-polarization
#20
Shyi-Chyi Wang, Tricia Yu Feng Low, Yukako Nishimura, Laurent Gole, Weimiao Yu, Fumio Motegi
Cell polarization enables zygotes to acquire spatial asymmetry, which in turn patterns cellular and tissue axes during development. Local modification in the actomyosin cytoskeleton mediates spatial segregation of partitioning-defective (PAR) proteins at the cortex, but how mechanical changes in the cytoskeleton are transmitted to PAR proteins remains elusive. Here we uncover a role of actomyosin contractility in the remodelling of PAR proteins through cortical clustering. During embryonic polarization in Caenorhabditis elegans, actomyosin contractility and the resultant cortical tension stimulate clustering of PAR-3 at the cortex...
July 24, 2017: Nature Cell Biology
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