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Spinal neoplasm

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https://www.readbyqxmd.com/read/28089196/descriptive-analysis-of-unplanned-readmission-and-reoperation-rates-after-intradural-spinal-tumor-resection
#1
Christian Fisahn, Felipe H Sanders, Marc Moisi, Jeni Page, Peter C Oakes, Mary Wingerson, Joe Dettori, R Shane Tubbs, Parthasarathi Chamiraju, Peter Nora, David Newell, Johnny Delashaw, Rod J Oskouian, Jens R Chapman
INTRODUCTION: Spinal cord tumors (SCT) are relatively uncommon and usually require surgical treatment. Readmission within 30days after discharge is an important indicator of health care quality. The aim of this study was to investigate the rates and causes of unplanned readmissions and reoperations after SCT surgery. METHODS: A retrospective analysis of patients' charts at a single center from May 2007 to September 2015 was completed. INCLUSION CRITERIA: history of laminectomy with excision of neoplasm in the spinal cord...
January 11, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28009635/perioperative-and-anesthetic-considerations-for-neurosurgical-laser-interstitial-thermal-therapy-ablations
#2
Federico Jimenez-Ruiz, Benjamin Arnold, Claudio E Tatsui, Juan P Cata
OBJECTIVE: To describe the anesthetic considerations in patients undergoing laser interstitial thermal therapy (LITT) for neurosurgical procedures. BACKGROUND: LITT for neurosurgical procedures is being increasingly used in a variety of central nervous system diseases. Several studies have demonstrated promising results including a shorter hospital stay. Given the rising trend for the use of LITT, anesthesiologists need to be familiar with the anesthetic considerations to provide care for patients undergoing these types of procedures...
December 22, 2016: Journal of Neurosurgical Anesthesiology
https://www.readbyqxmd.com/read/27956254/braf-mutated-pleomorphic-xanthoastrocytoma-of-the-spinal-cord-with-eventual-anaplastic-transformation
#3
Christopher S Hong, Joshua L Wang, David Dornbos, Amy Joehlin-Price, James Bradley Elder
BACKGROUND: Pleomorphic xanthoastrocytoma (PXA) is an uncommon, primary neoplasm of the central nervous system with a relatively favorable prognosis. Most patients are managed with surgery alone and experience significant long-term survival. PXAs occur most commonly along the superficial surfaces of the temporal lobes. Although these tumors may occur in other regions of the brain, their origin within the spinal cord is rare, and it is unclear whether spinal cord PXAs should be managed differently from their intracranial counterparts...
December 10, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27920879/recurrent-solitary-fibrous-tumor-of-lumbar-spine-with-vertebral-body-involvement-imaging-features-and-differential-diagnosis-with-report-of-a-case
#4
Zerwa Farooq, Zain Badar, Daniel Zaccarini, Felix B Tavernier, Anthony Mohamed, Rajiv Mangla
Solitary fibrous tumors (SFTs) of the spine are exceedingly rare tumors of mesenchymal origin. Most spinal SFTs arise from the thoracic spine, followed by cervical spine, and last lumbar spine with only 6 cases reported in literature. SFTs represent a wide range of neoplasms, ranging from benign to malignant. These tumors can develop a late recurrence, even after a decade or more of initial presentation, requiring long-term follow-up. We present a case of recurrent SFT of the lumbar spine with vertebral body involvement, presenting more than a decade after initial resection...
December 2016: Radiology case reports
https://www.readbyqxmd.com/read/27913780/multifocal-polymorphous-hemangioendothelioma-of-the-liver-case-report-and-review-of-literature
#5
Siba El Hussein, Yumna Omarzai
We report a case of polymorphous hemangioendothelioma, a rare vascular neoplasm, arising in the liver of a 51-year-old woman. Microscopically, this neoplasm is characterized by a polymorphous blend of solid, primitive vascular and angiomatous areas in variable proportions. Polymorphous hemangioendothelioma is considered to be an intermediate-grade vascular neoplasm. In most of the reported cases, its occurrence has been in lymph nodes, but a few cases have been found in extranodal sites such as the mediastinum, spinal cord, and liver...
December 2, 2016: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/27879953/elective-laminectomy-and-excision-of-the-thoracic-spine-neoplasm-an-evaluation-of-early-outcomes
#6
Pavan S Upadhyayula, John K Yue, Erik I Curtis, Joseph D Ciacci
BACKGROUND: Laminectomy plus excision of spinal neoplasms is commonly performed. The current study examines risk profiles associated with elective laminectomies of benign, malignant primary, and secondary/metastatic neoplasms of the thoracic spine. METHODS: Adult patients undergoing elective thoracic laminectomy and excision of spinal neoplasm were abstracted from ACS-NSQIP years 2011-2014. Patients were classified into three cohorts: benign primary, malignant primary, secondary/metastatic...
November 23, 2016: Journal of Neurosurgical Sciences
https://www.readbyqxmd.com/read/27872537/large-retroperitoneal-extraosseous-osteosarcoma-invading-into-the-spine-a-case-report
#7
Anish P Nagpal, Somesh Chandra, Shaifali Goel
Extraosseous osteogenic sarcoma is a very rare malignant neoplasm. The most common sites are the extremities, thorax, and the abdomen. Retroperitoneal osteosarcomas are rare and very few cases have been reported. They are similar in their biology to high-grade soft tissue sarcomas. R0 resection appears to be the best possible treatment for these tumors but there are no published cases on how to manage them when it involves posterior and intra-spinal regions. We report a 62-year-old male who presented with a backache, and investigations revealed a large retroperitoneal fibrosarcoma invading into the lumbar spine, but was found to be an extra osseous osteosarcoma on final histopathological examination...
December 2016: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27870071/eosinophilic-meningomyelitis-associated-with-t-cell-lymphoma-in-a-cat
#8
Kathryn Y Bray, Karen R Muñana, Kristina Meichner, Laura A White, Gabriela Seiler
A 12-year-old cat was presented for evaluation of progressive tetraparesis. Magnetic resonance imaging of the cervical spine demonstrated T2-hyperintensity, and contrast enhancement within the C4-C7 spinal cord, with marked meningeal contrast enhancement and segmental nerve root thickening. Lumbar cerebrospinal fluid contained 407 total nucleated cells/μL, with 99% eosinophils. The cat transiently improved with prednisolone, clindamycin, and ivermectin therapy, but subsequently worsened and was euthanized...
December 2016: Veterinary Clinical Pathology
https://www.readbyqxmd.com/read/27857459/primary-diffuse-leptomeningeal-oligodendrogliomatosis-a-case-report-and-literature-review
#9
Amarnath Chellathurai, Jay S Vaidya, Gopinathan Kathirvelu, Periakaruppan Alagappan
Primary leptomeningeal oligodendrogliomatosis (PLO) is a rare low-grade intracranial and spinal canal subarachnoid neoplasm without an obvious primary neoplasm in the brain or spinal cord parenchyma. We present here the serial progression of radiological findings of this rare disease in a 2-year-old male child whose clinical status deteriorated over a period of 4 months with the main complaint of partial seizures. During this period, the MR findings progressed from mild hydrocephalus with minimal leptomeningeal enhancement to leptomeningeal multiple cystic lesions in the entire neuraxis including the spine...
July 2016: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/27818821/disseminated-cerebrospinal-embryonal-tumor-in-the-adult
#10
Alessandro Caporlingua, Daniele Armocida, Federico Caporlingua, Gennaro Lapadula, Grazia Maria Elefante, Manila Antonelli, Maurizio Salvati
Introduction. According to the 2016 World Health Organization classification of Tumors of the Central Nervous System, the term Primitive Neuroectodermal Tumor has been replaced by the term Embryonal Tumor (ET). We present a case of disseminated cerebrospinal ET presenting in an adult patient. Illustrative Case. A 49-year-old male presenting with low back pain, dysuria, and hypoesthesia of the lower extremities referred to our emergency department. Brain and whole spine contrast-enhanced MRI documented a diffusively disseminated heterogeneous neoplasm with intradural extra- and intramedullary involvement of the cervicothoracic tract and cauda equina...
2016: Case Reports in Pathology
https://www.readbyqxmd.com/read/27761174/spinal-metastases-of-extramammary-paget-disease-with-radiologic-pathologic-correlation
#11
Jason T Little, Vance T Lehman, Jonathan M Morris, Julia S Lehman, Felix E Diehn
Extramammary Paget disease (EMPD) is an uncommon malignancy. It manifests either in the primary form in the skin as an intraepithelial neoplasm, or in secondary form as pagetoid (intraepithelial) spread of an underlying internal carcinoma to the skin. Although local invasion and recurrence of primary extramammary Paget disease are relatively frequent, widespread metastases are rare. As such, there are very few reports and little characterization of the radiologic features of widespread spinal metastases. To our knowledge, there are no prior reports of a metastatic extramammary Paget disease presenting as a painful pathologic vertebral body compression fracture...
May 2016: Journal of Radiology Case Reports
https://www.readbyqxmd.com/read/27757435/spinal-myxopapillary-ependymoma-with-interval-drop-metastasis-presenting-as-cauda-equina-syndrome-case-report-and-review-of-literature
#12
Shrikant V Rege, Sharadendu Narayan, Harshad Patil, Abhishek Songara
Myxopapillary ependymoma is a benign slow-growing tumour, arising predominantly in the region of the filum terminale. It has been designated histologically as grade I neoplasm according to the 2007 WHO classification. Despite this benign character dissemination and metastasis along the cerebrospinal axis and metastasis to distant sites have occasionally been reported. There have been previously reported cases of drop metastasis from MPE, however in three of these cases the drop metastasis was diagnosed with concurrent primary spinal MPE...
September 2016: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/27746887/soft-tissue-myoepithelial-carcinoma-of-the-neck-with-spinal-invasion
#13
Elias Moussaly, Bassel Nazha, Shiksha Kedia, Qing Chang, Frank Forte
Soft tissue myoepithelial neoplasms are a rare yet diverse group of tumors, ranging from benign to malignant lesions. Their presentation in the head and neck region is uncommon and represents a challenging diagnosis. Early identification of myoepithelial carcinoma is crucial given its more aggressive course compared to its benign counterpart, although the histopathological distinction between the two can be difficult. EWSR1 gene rearrangement is found in half the cases and has a speculative role in pathogenesis...
September 5, 2016: Rare Tumors
https://www.readbyqxmd.com/read/27713062/intradural-carcinoid-tumor-found-in-a-patient-with-no-history-of-cancer-a-case-report
#14
Jason R Audlin, Gaurav Khullar, Eric M Deshaies, Swamy Kurra, William F Lavelle
BACKGROUND: Carcinoid tumors are rare neoplasms that often arise from the gastrointestinal or respiratory tracts. They often metastasize to bone tissue, as well as pancreatic and hepatic sites. The central nervous system and most specifically the spinal cord are rarely involved. Primary Carcinoid tumors of the CNS are even rarer. CASE DESCRIPTION: A 58 year-old man presented with progressive bilateral lower extremity weakness and a negative history of cancer. Imaging revealed an intradural mass at the L1 and L2 spinal levels...
October 3, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/27687936/distribution-of-feline-lymphoma-in-the-central-and-peripheral-nervous-systems
#15
REVIEW
Maria Teresa Mandara, Luca Motta, Pietro Calò
In cats, lymphoma (lymphosarcoma) is the most common neoplasm affecting the spinal cord and the second most common intracranial tumour. Although lymphoma commonly develops in the spinal cord as a part of a multicentric process, a primary form may occur. Lymphoma can exhibit a wide range of morphological patterns, including intraparenchymal brain mass, lymphomatosis cerebri, intravascular lymphoma, lymphomatous choroiditis and meningitis, extradural, intradural-extramedullary or intramedullary lymphoma in the spinal cord, or neurolymphomatosis in the peripheral nerves...
October 2016: Veterinary Journal
https://www.readbyqxmd.com/read/27666764/low-grade-schwann-cell-neoplasms-with-leptomeningeal-dissemination-clinicopathologic-and-autopsy-findings
#16
Erika F Rodriguez, Jaishri Blakeley, Shannon Langmead, Alessandro Olivi, Anthony Tufaro, Abeer Tabbarah, Gail Berkenblit, Justin M Sacks, Scott D Newsome, Elizabeth Montgomery, Fausto J Rodriguez
Leptomeningeal dissemination of low grade Schwann cell neoplasms is an exceptionally rare occurrence, and has not been well documented in the literature. We encountered two cases of leptomeningeal dissemination of low grade Schwann cell neoplasms. Patient 1 was a 63-year-old woman with NF1 and a progressive low grade MPNST developing from a diffuse/plexiform orbital neurofibroma that arose in childhood. The neoplasm demonstrated local and leptomeningeal dissemination intracranially leading to the patient's death...
September 22, 2016: Human Pathology
https://www.readbyqxmd.com/read/27664341/disparities-in-reportable-quality-metrics-by-insurance-status-in-the-primary-spine-neoplasm-population
#17
Syed K Mehdi, Joseph E Tanenbaum, Vincent J Alentado, Jacob A Miller, Daniel Lubelski, Edward C Benzel, Thomas E Mroz
BACKGROUND CONTEXT: The Centers for Medicare and Medicaid Services (CMS) defines "adverse quality events" as the incidence of certain complications such as postsurgical hematoma or iatrogenic pneumothorax during an inpatient stay. Patient safety indicators (PSI) are a means to measure the incidence of these adverse events. When adverse events occur, reimbursement to the hospital decreases. The incidence of adverse quality events among patients hospitalized for primary spinal neoplasms is unknown...
September 21, 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/27616318/neoplastic-and-paraneoplastic-involvement-of-the-spinal-cord
#18
John Michael Hazenfield, Mary F Gaskill-Shipley
Neoplasia of the spinal cord, including both primary and metastatic tumors, is relatively rare, representing 4%-10% of all central nervous system tumors, and can present a diagnostic challenge to the radiologist. More than 90% of primary spinal cord neoplasms are derived from the glial cell lineage, including the 2 most common tumors ependymoma and astrocytoma. However, less common spinal cord tumors, including metastatic disease, as well as nonneoplastic and paraneoplastic processes should be considered in the diagnosis of intramedullary spinal cord lesions...
October 2016: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/27616316/toxic-and-metabolic-myelopathies
#19
Joana Ramalho, Renato Hoffmann Nunes, Antonio José da Rocha, Mauricio Castillo
Myelopathy describes any neurologic deficit related to the spinal cord. It is most commonly caused by its compression by neoplasms, degenerative disc disease, trauma, or infection. Less common causes of myelopathy include spinal cord tumors, infection, inflammatory, neurodegenerative, vascular, toxic, and metabolic disorders. Conditions affecting the spinal cord must be recognized as early as possible to prevent progression that may lead to permanent disability. Biopsy is rarely performed, thus the diagnosis and management rely on patient׳s history, physical examination, laboratory results, and imaging findings...
October 2016: Seminars in Ultrasound, CT, and MR
https://www.readbyqxmd.com/read/27613377/peripheral-primitive-neuroectodermal-tumors-of-the-spine-a-case-report-and-review-of-the-literature
#20
Mouna Khmou, Abderrahmane Malihy, Najat Lamalmi, Lamia Rouas, Zaitouna Alhamany
BACKGROUND: Peripheral primitive neuroectodermal tumors are extremely rare tumors in the spine; only 18 cases of extra-dural peripheral primitive neuroectodermal tumor cervical region have been reported. The aim of this report is to highlight the challenges in diagnosis and management of this condition. CASE PRESENTATION: We present a case of 5-year-old Moroccan boy, who presented with torticollis for 1 month. Computed tomography scan and Magnetic resonance imaging of the cervical spine revealed an extradural, dumbbell-shaped mass with extra-spinal extension at the left C1-C6 level...
September 9, 2016: BMC Research Notes
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