keyword
MENU ▼
Read by QxMD icon Read
search

typhoid

keyword
https://www.readbyqxmd.com/read/29688492/adverse-events-in-vaccinations-for-travelers-a-1-year-prospective-survey-in-a-travel-clinic-in-germany
#1
Günther Slesak, Ralf Fleck, Helmut Scherbaum, Gunnar Blumenstock, Johannes Schäfer
Background: The study goal was to assess and compare adverse events (AE) of current vaccinations for travelers under 'real-life conditions'. Methods: A prospective observational online questionnaire study was performed from May 2015 till April 2016 in a travel clinic in Germany. Online questionnaire links were sent 1 week after the first vaccination date. Severity was rated on a scale from 1 to 5 (minor to very severe AE). Results: Of 1357 vaccinees 781 (57...
January 1, 2018: Journal of Travel Medicine
https://www.readbyqxmd.com/read/29684710/genomic-characterization-of-endemic-salmonella-enterica-serovar-typhimurium-and-salmonella-enterica-serovar-i-4-5-12-i-isolated-in-malaysia
#2
Soo Tein Ngoi, Kien-Pong Yap, Kwai Lin Thong
Salmonella enterica serovar Typhimurium (S. Typhimurium) and the monophasic variant Salmonella I 4,[5],12:i:- are two clinically-important non-typhoidal Salmonella serovars worldwide. However, the genomic information of these two organisms, especially the monophasic variant, is still lacking in Malaysia. The objective of the study was to compare the genomic features of a monophasic variant and two endemic S. Typhimurium strains isolated from humans. All three strains were subjected to whole genome sequencing followed by comparative genomic and phylogenetic analyses...
April 20, 2018: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/29684022/open-label-comparative-trial-of-mono-versus-dual-antibiotic-therapy-for-typhoid-fever-in-adults
#3
Niv Zmora, Sudeep Shrestha, Ami Neuberger, Yael Paran, Rajendra Tamrakar, Ashish Shrestha, Surendra K Madhup, T R S Bedi, Rajendra Koju, Eli Schwartz
BACKGROUND: Emerging resistance to antibiotics renders therapy of Typhoid Fever (TF) increasingly challenging. The current single-drug regimens exhibit prolonged fever clearance time (FCT), imposing a great burden on both patients and health systems, and potentially contributing to the development of antibiotic resistance and the chronic carriage of the pathogens. The aim of our study was to assess the efficacy of combining third-generation cephalosporin therapy with azithromycin on the outcomes of TF in patients living in an endemic region...
April 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29684021/laboratory-and-molecular-surveillance-of-paediatric-typhoidal-salmonella-in-nepal-antimicrobial-resistance-and-implications-for-vaccine-policy
#4
Carl D Britto, Zoe A Dyson, Sebastian Duchene, Michael J Carter, Meeru Gurung, Dominic F Kelly, David R Murdoch, Imran Ansari, Stephen Thorson, Shrijana Shrestha, Neelam Adhikari, Gordon Dougan, Kathryn E Holt, Andrew J Pollard
BACKGROUND: Children are substantially affected by enteric fever in most settings with a high burden of the disease, including Nepal. However pathogen population structure and transmission dynamics are poorly delineated in young children, the proposed target group for immunization programs. Here we present whole genome sequencing and antimicrobial susceptibility data on 198 S. Typhi and 66 S. Paratyphi A isolated from children aged 2 months to 15 years of age during blood culture surveillance at Patan Hospital, Nepal, 2008-2016...
April 23, 2018: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/29681410/development-of-a-bivalent-conjugate-vaccine-candidate-against-malaria-transmission-and-typhoid-fever
#5
So Jung An, Puthupparampil V Scaria, Beth Chen, Emma Barnafo, Olga Muratova, Charles Anderson, Lynn Lambert, Myung Hwa Chae, Jae Seung Yang, Patrick E Duffy
Immune responses to poorly immunogenic antigens, such as polysaccharides, can be enhanced by conjugation to carriers. Our previous studies indicate that conjugation to Vi polysaccharide of Salmonella Typhi may also enhance immunogenicity of some protein carriers. We therefore explored the possibility of generating a bivalent vaccine against Plasmodium falciparum malaria and typhoid fever, which are co-endemic in many parts of the world, by conjugating Vi polysaccharide, an approved antigen in typhoid vaccine, to Pfs25, a malaria transmission blocking vaccine antigen in clinical trials...
April 19, 2018: Vaccine
https://www.readbyqxmd.com/read/29680695/microbiological-quality-and-antimicrobial-resistance-characterization-of-salmonella-spp-in-fresh-milk-value-chains-in-ghana
#6
Angela Parry-Hanson Kunadu, Mark Holmes, Eric L Miller, Andrew J Grant
Consumer perception of poor hygiene of fresh milk products is a major barrier to promotion of milk consumption as an intervention to alleviate the burden of malnutrition in Ghana. Fresh milk is retailed raw, boiled, or processed into unfermented cheese and spontaneously fermented products in unlicensed outlets. In this study, we have determined microbiological quality of informally retailed fresh milk products and characterized the genomic diversity and antimicrobial resistance (AMR) patterns of non-typhoidal Salmonella (NTS) in implicated products...
April 14, 2018: International Journal of Food Microbiology
https://www.readbyqxmd.com/read/29678231/incorporation-of-membrane-anchored-flagellin-into-salmonella-gallinarum-bacterial-ghosts-induces-early-immune-responses-and-protection-against-fowl-typhoid-in-young-layer-chickens
#7
Irshad Ahmed Hajam, Je Hyoung Kim, John Hwa Lee
The present study aimed to investigate whether the incorporation of flagellin, a TLR5 agonist, in the bacterial ghosts (BGs) of Salmonella Gallinarum can enhance protective immune responses against fowl typhoid, a septicemic disease of poultry, in chickens. BGs are empty cell envelopes derived from Gram-negative bacteria through the bacteriophage phiX174 gene E mediated lysis. In this study, the S. Gallinarum ghosts carrying flagellin were genetically constructed utilizing a lysis plasmid pJHL184-flagellin, designed for the coexpression of the flagellin and the lysis protein E...
May 2018: Veterinary Immunology and Immunopathology
https://www.readbyqxmd.com/read/29666727/typhoid-fever-due-to-extended-spectrum-%C3%AE-lactamase-producing-salmonella-enterica-serovar-typhi-a-case-report-and-literature-review
#8
Abdul Azeez Ahamed Riyaaz, Vindya Perera, Sabaratnam Sivakumaran, Nelun de Silva
Emergence of cephalosporin-resistant strains of Salmonella enterica serovar Typhi is a cause of concern in the management of enteric fever. Cephalosporin resistance in Salmonella species is mainly due to the production of extended-spectrum β -lactamases (ESBLs). The majority of ESBLs in Salmonella enterica serovar Typhi are derivatives of the TEM, SHV, and CTX-M β -lactamase families. Of these, CTX-M appears to be predominant. This paper discusses the detection and molecular characterization of an ESBL-producing Salmonella enterica serovar Typhi strain isolated from a patient who was admitted to a private hospital in Sri Lanka...
2018: Case Reports in Infectious Diseases
https://www.readbyqxmd.com/read/29661581/typhoid-vaccines-who-position-paper-march-2018-recommendations
#9
World Health Organization
This article presented the World Health Organization's (WHO) recommendations on the use of Typhoid vaccines excerpted from the Typhoid vaccines: WHO position paper - March 2018 published in the Weekly Epidemiological Record (World Health Organization, 2018) [1]. This position paper replaces the 2008 WHO position paper on typhoid vaccines (WHO, 2008) [2]. It re-emphasizes the importance of vaccination to control typhoid fever and presents the WHO recommendations on the use of a new generation of typhoid conjugate vaccines...
April 13, 2018: Vaccine
https://www.readbyqxmd.com/read/29649855/a-salmonella-typhi-ghost-induced-by-the-e-gene-of-phage-%C3%AF-x174-stimulates-dendritic-cells-and-efficiently-activates-the-adaptive-immune-response
#10
Gayeon Won, Seong Kug Eo, Sang-Youel Park, Jin Hur, John Hwa Lee
We previously genetically engineered a Salmonella Typhi bacterial ghost (STG) as a novel inactivated vaccine candidate against typhoid fever. The underlying mechanism employed by the ghost to stimulate the adaptive immune response remains to be investigated. In this study, we aimed to evaluate the immunostimulatory effect of STG on mouse bone marrow-derived dendritic cells (BMDCs) and its activation of the adaptive immune response in vitro . Immature BMDCs were stimulated with STG, which efficiently stimulated maturation events in BMDCs, as indicated by up-regulated expression of CD40, CD80, and MHC-II molecules on CD11+ BMDCs...
April 12, 2018: Journal of Veterinary Science
https://www.readbyqxmd.com/read/29643891/assessment-of-freshwater-springs-associated-diseases-and-indigenous-perception-in-ghizer-gilgit-baltistan-pakistan
#11
Shaukat Ali, Rubina, Sadiq Hussain
Objective: To assess the quality of freshwater aquifers (springs) associated diseases, and indigenous perception in Ghizer, Gilgit-Baltistan. Methods: This was a cross-sectional study conducted at the department of environmental science, Karakoram International University Gilgit after approval from departmental research committee. In order to get the most accurate results, 18 water samples in triplicates were collected according to our lab own set of sampling standard operating procedures (SOPs) using pre-sterilized bottles of 100 ml from June 2016 to August 2016 along with associated diseases record and structured interviews from indigenous population...
January 2018: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/29642473/resistance-to-carbapenems-in-non-typhoidal-salmonella-enterica-serovars-from-humans-animals-and-food
#12
REVIEW
Javier Fernández, Beatriz Guerra, M Rosario Rodicio
Non-typhoidal serovars of Salmonella enterica (NTS) are a leading cause of food-borne disease in animals and humans worldwide. Like other zoonotic bacteria, NTS have the potential to act as reservoirs and vehicles for the transmission of antimicrobial drug resistance in different settings. Of particular concern is the resistance to critical "last resort" antimicrobials, such as carbapenems. In contrast to other Enterobacteriaceae (e.g., Klebsiella pneumoniae , Escherichia coli , and Enterobacter , which are major nosocomial pathogens affecting debilitated and immunocompromised patients), carbapenem resistance is still very rare in NTS...
April 8, 2018: Veterinary Sciences
https://www.readbyqxmd.com/read/29628924/defective-phagocytic-properties-of-hiv-infected-macrophages-how-might-they-be-implicated-in-the-development-of-invasive-salmonella-typhimurium
#13
REVIEW
Gabrielle Lê-Bury, Florence Niedergang
Human immunodeficiency virus type 1 (HIV-1) infects and kills T cells, profoundly damaging the host-specific immune response. The virus also integrates into memory T cells and long-lived macrophages, establishing chronic infections. HIV-1 infection impairs the functions of macrophages both in vivo and in vitro , which contributes to the development of opportunistic diseases. Non-typhoidal Salmonella enterica serovar Typhimurium has been identified as the most common cause of bacterial bloodstream infections in HIV-infected adults...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29627914/the-influence-of-feed-supplementation-with-probiotic-strain-lactobacillus-reuteri-ccm-8617-and-alginite-on-intestinal-microenvironment-of-spf-mice-infected-with-salmonella-typhimurium-ccm-7205
#14
Soňa Gancarčíková, Radomíra Nemcová, Miroslav Popper, Gabriela Hrčková, Ľuboslava Sciranková, Marián Maďar, Dagmar Mudroňová, Štefan Vilček, Rudolf Žitňan
Alginite is a non-ore raw material arising by fossilization of accumulated organic (algae) and inorganic material, particularly clay, carbonates, quartz, and amorphous modification of silicic acid in the aqueous environment. Humic acids as a component of organic portion of alginite are known for very good buffering ability which allows them to stabilise pH throughout the digestion system of animals, stimulate receptors of the immune system in intestinal villi against pathogenic bacteria, and support proliferation and activity of beneficial bacteria (lactobacilli, bifidobacteria, and similar)...
April 7, 2018: Probiotics and Antimicrobial Proteins
https://www.readbyqxmd.com/read/29625787/tropical-diseases-in-the-icu-a-syndromic-approach-to-diagnosis-and-treatment
#15
Dilip R Karnad, Guy A Richards, Gisele Sampaio Silva, Pravin Amin
Tropical infections form 20-30% of ICU admissions in tropical countries. Diarrheal diseases, malaria, dengue, typhoid, rickettsial diseases and leptospirosis are common causes of critical illness. Overlapping clinical features makes initial diagnosis challenging. A systematic approach involving (1) history of specific continent or country of travel, (2) exposure to specific environments (forests or farms, water sports, consumption of exotic foods), (3) incubation period, and (4) pattern of organ involvement and subtle differences in manifestations help in differential diagnosis and choice of initial empiric therapy...
March 27, 2018: Journal of Critical Care
https://www.readbyqxmd.com/read/29623212/first-report-of-lyme-disease-in-nepal
#16
Sher Bahadur Pun, Sumit Agrawal, Santoshananda Jha, Lila Nath Bhandari, Bimal Sharma Chalise, Abadhesh Mishra, Rajesh Shah
Introduction: Lyme disease is a tick-borne illness caused by the spirochete Borrelia burgdorferi and is widely reported in the USA, Central Europe, South East Asia and Latin America. Until recently, no scientific report regarding Lyme disease in Nepal had been published. Case presentation: A 32-year-old, previously healthy female visited the hospital with a history of joint pains, fatigue, neck stiffness, tingling sensation and headache. She was initially treated for typhoid fever, brucellosis and malaria, but did not show significant improvement...
March 2018: JMM Case Reports
https://www.readbyqxmd.com/read/29621969/baseline-widal-titre-among-healthy-adult-males-from-the-greater-mymensingh-division-of-bangladesh
#17
Arifuzzaman Khan, Fahim Ashher, Fahmida Khanam, Marufur Rahman, Momen Khan, Shyamal Kumar Paul, Akram Hossain
Widal agglutination test is arguably the most widely used laboratory investigation for diagnosis of Typhoid, especially in developing countries where blood culture is often inaccessible. However, the interpretation of the test still remains a controversial topic particularly in the context of endemic regions such as Bangladesh, as agglutination test is often found positive in varied and higher titrations among a large percentage of healthy population. Paired Widal tests are often not feasible, hence single unpaired test has to be used for screening and diagnosis...
April 5, 2018: Infectious Disorders Drug Targets
https://www.readbyqxmd.com/read/29616895/ceftriaxone-resistant-salmonella-typhi-carries-an-inci1-st31-plasmid-encoding-ctx-m-15
#18
Bilal Djeghout, Senjuti Saha, Mohammad Saiful Islam Sajib, Arif Mohammad Tanmoy, Maksuda Islam, Gemma L Kay, Gemma C Langridge, Hubert P Endtz, John Wain, Samir K Saha
PURPOSE: Ceftriaxone is the drug of choice for typhoid fever and the emergence of resistant Salmonella Typhi raises major concerns for treatment. There are an increasing number of sporadic reports of ceftriaxone-resistant S. Typhi and limiting the risk of treatment failure in the patient and outbreaks in the community must be prioritized. This study describes the use of whole genome sequencing to guide outbreak identification and case management. METHODOLOGY: An isolate of ceftriaxone-resistant S...
April 4, 2018: Journal of Medical Microbiology
https://www.readbyqxmd.com/read/29616644/etiological-therapeutic-and-prognostic-particularities-of-primary-biliary-peritonitis-in-tropical-environments
#19
S Ouedraogo, M Windsouri, J T Sawadogo, M Zida, E Ouangre, S S Traore
To describe the etiological, therapeutic, and prognostic aspects of primary biliary peritonitis in Burkina Faso. This retrospective study reviewed records of all patients admitted for primary biliary peritonitis at Tenkodogo Regional Hospital (Burkina Faso) from 2010 through 2016. Cases of secondary biliary peritonitis have been excluded. Thirty patients were identified. Their average age was 26.5 years. Fourteen patients were under 12 years of age. The reasons for consultation were dominated by abdominal pain (in all cases) and bile-induced vomiting (in 22 cases)...
February 1, 2018: Médecine et Santé Tropicales
https://www.readbyqxmd.com/read/29616614/rise-and-fall-of-outbreak-specific-clone-inside-endemic-pulsotype-of-salmonella-4-5-12-i-insights-from-high-resolution-molecular-surveillance-in-emilia-romagna-italy-2012-to-2015
#20
Marina Morganti, Luca Bolzoni, Erika Scaltriti, Gabriele Casadei, Elena Carra, Laura Rossi, Paola Gherardi, Fabio Faccini, Norma Arrigoni, Anna Rita Sacchi, Marco Delledonne, Stefano Pongolini
Background and aimEpidemiology of human non-typhoid salmonellosis is characterised by recurrent emergence of new clones of the pathogen over time. Some clonal lines of Salmonella have shaped epidemiology of the disease at global level, as happened for serotype Enteritidis or, more recently, for Salmonella 4,[5],12:i:-, a monophasic variant of serotype Typhimurium. The same clonal behaviour is recognisable at sub-serotype level where single outbreaks or more generalised epidemics are attributable to defined clones...
March 2018: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
keyword
keyword
31812
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"