keyword
MENU ▼
Read by QxMD icon Read
search

ENT

keyword
https://www.readbyqxmd.com/read/29784314/identification-of-new-diterpene-esters-from-green-arabica-coffee-beans-and-their-platelet-aggregation-accelerating-activities
#1
Xia Wang, QianQian Meng, XingRong Peng, GuiLin Hu, MingHua Qiu
Eight new ent-kaurane diterpene fatty acid esters, namely caffarolides A-H (1-8), were isolated from green beans of Coffea arabica. Their chemical structures were confirmed by extensive spectroscopic analysis including 1D, 2D NMR (HSQC, HMBC, 1 H-1 H COSY, and ROESY), HRMS, IR and CD spectra and by GC-FID analysis. Interestingly, the diterpene moiety of these new compounds first occurred in genus Coffea. All the isolates were evaluated for platelet aggregation activity in vitro. As the results, caffarolides C, D and F (3, 4 and 6) showed induction effect for platelet aggregation and the possible structure-activity relationships have been discussed briefly...
October 15, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29784244/rehabilitation-of-the-laryngectomised-patient-recommendations-of-the-spanish-society-of-otolaryngology-and-head-and-neck-surgery
#2
Pedro Díaz de Cerio Canduela, Ismael Arán González, Rafael Barberá Durban, Alexander Sistiaga Suárez, Marc Tobed Secall, Pablo L Parente Arias
Total laryngectomy remains essential treatment for locally advanced laryngeal carcinoma, related to better survival rates. However, it involves changes for the patient, such as the inability to communicate verbally, breathing or aesthetic changes, which affect their quality of life and require comprehensive rehabilitation. This paper was written by the total laryngectomy rehabilitation workgroup of the National Head and Neck and Skull Base working committee of the Spanish Society of Otolaryngology and Head and Neck Surgery...
May 18, 2018: Acta Otorrinolaringológica Española
https://www.readbyqxmd.com/read/29784040/antimicrobial-resistance-profile-of-staphylococcus-aureus-isolated-from-patients-with-infection-at-tikur-anbessa-specialized-hospital-addis-ababa-ethiopia
#3
Sileshi Tadesse, Haile Alemayehu, Admasu Tenna, Getachew Tadesse, Tefaye Sisay Tessema, Workineh Shibeshi, Tadesse Eguale
BACKGROUND: Staphylococcus aureus is one of the major pathogens of public health importance responsible for various forms of infection. Development of resistance to commonly used antimicrobials limited treatment options against infections due to this pathogen. Antimicrobial resistance profile of Staphylococcus aureus isolated from patients with surgical site infection and ear infection and corresponding nasal swab was investigated in Tikur Anbessa Specialized Hospital (TASH), Addis Ababa, Ethiopia...
May 21, 2018: BMC Pharmacology & Toxicology
https://www.readbyqxmd.com/read/29782072/a-comprehensive-analysis-of-all-patients-n-509-undergoing-tonsillectomy-during-one-year-in-a-large-centralised-service
#4
Frith Cull, Shimin Choo, Thomas D Milner, Georgios Kontorinis, John Marshall
The annual post-tonsillectomy haemorrhage rates in a large tertiary referral centre were over four times higher than the reported National Prospective Tonsillectomy Audit (NPTA) adult haemorrhage rates. Comprehensive data capture in the study and a single centralised ENT service ensured accuracy of reported outcomes. 'Hot' techniques were not inferior to cold steel dissection methods, with a combination of 'hot' and 'cold' techniques generating the lowest post-tonsillectomy haemorrhage risk. The only other risk factor for post-tonsillectomy haemorrhage identified in the study was male gender...
May 21, 2018: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29780265/does-focused-and-dedicated-teaching-improve-the-confidence-of-gp-trainees-to-diagnose-and-manage-common-acute-ent-pathologies-in-primary-care
#5
Vikas Acharya, Matthew Haywood, Naomi Kokkinos, Anisha Raithatha, Sinthuja Francis, Rishi Sharma
Background: General practitioners (GPs) are key members of the health care profession who are required to have a considerable breadth of knowledge to manage and treat patients effectively in the community. Their skills and experience varies depending on the medical school they attended and their foundation training and specialist GP training schemes. Exposure to ear, nose, and throat (ENT)-specific pathology is often insufficient due to the lack of formal otolaryngology rotations, minimal relevant teaching opportunities, and inconsistencies in curricula, despite ENT-related pathology presentations being one of the commonest consultations in primary care...
2018: Advances in Medical Education and Practice
https://www.readbyqxmd.com/read/29774651/visible-light-induced-organic-photochemical-reactions-via-energy-transfer-pathways
#6
Wen-Jing Xiao, Quan-Quan Zhou, You-Quan Zou, Liang-Qiu Lu
Visible-light photocatalysis is a rapidly developing and powerful strategy to initiate organic transformations as it closely adheres to the tenants of green and sustainable chemistry. Generally, most visible-light-induced photochemical reactions occur through single-electron transfer (SET) pathways. Recently, visible-light-induced energy transfer (EnT) reactions have received considerable attentions from the synthetic community as this strategy provides a distinct reaction pathway, and remarkable achievements have been made in this field...
May 18, 2018: Angewandte Chemie
https://www.readbyqxmd.com/read/29771301/anti-tnf-levels-in-cord-blood-at-birth-are-associated-with-anti-tnf-type
#7
Shannon L Kanis, Alison de Lima, Cokkie van der Ent, Dimitris Rizopoulos, C Janneke van der Woude
Background and Aims: Pregnancy guidelines for women with Inflammatory Bowel Disease (IBD) provide recommendations regarding anti-TNF cessation during pregnancy, in order to limit fetal exposure. Although infliximab (IFX) leads to higher anti-TNF concentrations in cord blood than adalimumab (ADA), recommendations are similar. We aimed to demonstrate the effect of anti-TNF cessation during pregnancy on fetal exposure, for IFX and ADA separately. Methods: We conducted a prospective single center cohort study...
May 15, 2018: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/29771037/-association-between-airborne-pollen-distribution-and-allergic-diseases-in-beijing-urban-area
#8
X Y Wang, Z M Tian, H Y Ning, X Y Wang
Objective: The aim of this study is to investigate the impact of airborne pollen in urban Beijing area on the consultation rate of allergic diseases. Method: A modified pollen sampler was used to monitor the distribution of main airborne pollen during Jan 1st 2015 to Dec 31 2015.The consultation rate of allergic rhinitis and asthma was obtained meanwhile among allergy, ENT and pneumology department. Relationship between pollen and consultation rate was analyzed by Pearson index. Result: ①Through the whole year of 2015 the total quantity of pollens amounted to 76164 grains...
May 20, 2017: Journal of Clinical Otorhinolaryngology, Head, and Neck Surgery
https://www.readbyqxmd.com/read/29770288/infrasellar-endoscopic-endonasal-approach-for-a-pituitary-adenoma-extending-into-the-third-ventricle-with-anterior-displacement-of-the-pituitary-gland
#9
Georgios A Zenonos, Eric W Wang, Juan Carlos Fernandez-Miranda
Objectives  The current video presents the nuances of the infrasellar endoscopic endonasal approach for a pituitary adenoma extending into the third ventricle, with anterior displacement of the pituitary gland. Design  The video analyzes the presentation, preoperative workup and imaging, surgical steps and technical nuances of the surgery, the clinical outcome, and follow-up imaging. Setting  The patient was treated by a skull base team consisting of a neurosurgeon and an ENT surgeon at a teaching academic institution...
February 2018: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/29765779/effect-of-timing-of-initial-cataract-surgery-compliance-to-amblyopia-therapy-on-outcomes-of-secondary-intraocular-lens-implantation-in-chinese-children-a-retrospective-case-series
#10
Liuyang Li, Yan Wang, Caihong Xue
Purpose: As a secondary analysis, we reassess the association of initial congenital cataract surgery times, compliance to amblyopia therapy, and visual outcomes for a long-term follow-up in a secondary IOL implantation. Methods: Retrospective review of records of all infants with congenital cataracts who underwent secondary IOL implantation in the Eye and ENT Hospital of Fudan University from January 1, 2001, to December 31, 2007, and the minimum follow-up period was 5 years...
2018: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29765166/diagnosis-of-retrocochlear-lesions-with-emphasis-on-expansion-of-the-cerebellopontine-angle
#11
Bretislav Gal, Jan Rottenberg, Marta Pazourkova, Jiri Vanicek, Ermis Vogazianos
The correct diagnosis of CPA tumours is a relatively common issue in both neurological and ENT practice, the omission of which can have serious consequences for the patient. Properly set clinical guidelines and diagnostic protocols are key aspects of good clinical practice. In the case of CPA tumours, two options are available: the first is diagnosis with the help of an ABR as the primary tool for determining the group of patients with a possible tumour; the second is an MRI scan of the posterior cranial fossa...
April 17, 2018: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
https://www.readbyqxmd.com/read/29764740/are-computed-tomography-3d-measurements-of-the-upper-airways-in-mouth-breathing-children-in-agreement-with-the-ent-clinical-diagnosis-of-obstruction
#12
Bruno César Ladeira Vidigal, Carolina Morsani Mordente, Paula Loureiro Cheib, Flávio Ricardo Manzi, Letícia Paiva Franco, Helena Maria Gonçalves Becker, Bernardo Quiroga Souki
INTRODUCTION: Imaging studies have hystorically been used to support the clinical otorhinolaryngological evaluation of the upper respiratory tract for the diagnosis of obstructive causes of oral breathing. OBJECTIVE: The objective of this study was to compare 3D volumetric measurements of nasal cavity, nasopharynx and oropharynx of obstructed mouth-breathing children with measurements of non-obstructed mouth-breathing children. METHODS: This retrospective study included 25 mouth-breathing children aged 5-9 years evaluated by otorhinolaryngological clinical examination, flexible nasoendoscopy and full-head multi-slice computed tomography...
March 11, 2018: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/29762032/ent-kaurane-diterpenoids-with-neuroprotective-properties-from-corn-silk-zea-mays
#13
Xiao-Li Qi, Ying-Ying Zhang, Peng Zhao, Le Zhou, Xiao-Bo Wang, Xiao-Xiao Huang, Bin Lin, Shao-Jiang Song
Thirteen new ent-kaurane diterpenoids, stigmaydenes A-M (1-13), together with two known compounds (14, 15), were isolated from the crude extract of corn silk ( Zea mays). The structures of the compounds were confirmed by comprehensive spectroscopic analyses. The absolute configuration of compound 1 was defined by single-crystal X-ray diffraction. The absolute configurations of the compounds were also confirmed by comparison of experimental and calculated specific rotations. The compounds were evaluated for their neuroprotective effects against H2 O2 -induced SH-SY5Y cell injury, and compound 8 was active at 100 μM, as determined by flow cytometry (annexin V-FITC/PI staining) and Hoechst 33258 staining...
May 15, 2018: Journal of Natural Products
https://www.readbyqxmd.com/read/29759952/head-and-neck-anatomy-effect-of-focussed-near-peer-teaching-on-anatomical-confidence-in-undergraduate-medical-students
#14
Simon Morris, Max Sallis Osborne, Duncan Bowyer
OBJECTIVES: To assess the effect of near-peer head and neck anatomy teaching on undergraduates and to quantify the benefit from a focussed teaching course. Near-peer teaching involves colleagues within close seniority and age proximity teaching one another on a specified topic. DESIGN: Small group teaching sessions were delivered to medical students on 3 key areas of ENT anatomy. Participants were given a precourse and postcourse questionnaire to determine the benefit attained from the course...
May 11, 2018: Journal of Surgical Education
https://www.readbyqxmd.com/read/29758520/probing-the-transcriptome-of-aconitum-carmichaelii-reveals-the-candidate-genes-associated-with-the-biosynthesis-of-the-toxic-aconitine-type-c-19-diterpenoid-alkaloids
#15
Dake Zhao, Yong Shen, Yana Shi, Xingqiao Shi, Qin Qiao, Shuhui Zi, Erqiang Zhao, Diqiu Yu, Edward J Kennelly
Aconitum carmichaelii has long been used as a traditional Chinese medicine, and its processed lateral roots are known commonly as fuzi. Aconitine-type C19 -diterpenoid alkaloids accumulating in the lateral roots are some of the main toxicants of this species, yet their biosynthesis remains largely unresolved. As a first step towards understanding the biosynthesis of aconitine-type C19 -diterpenoid alkaloids, we performed de novo transcriptome assembly and analysis of rootstocks and leaf tissues of Aconitum carmichaelii by next-generation sequencing...
May 11, 2018: Phytochemistry
https://www.readbyqxmd.com/read/29752886/individual-funding-requests-a-flawed-process
#16
Matthew Cherko, Abigail Lamyman, Ian Bottrill
1.The Individual Funding Request (IFR) process was introduced by Clinical Commissioning Groups to regulate Procedures of Limited Clinical Value 2.In the South Buckinghamshire region, this affects common ENT procedures including adenotonsillectomy and grommet insertion 3.Only 3 of 118 applications for grommet insertion were rejected and the majority (23/27) of tonsillectomy rejections were due to insufficient supporting evidence from the patients' GPs 4.Despite the majority of applications eventually being accepted, the process has undoubtedly delayed treatment for our patients; impacting 18 week target times 5...
May 12, 2018: Clinical Otolaryngology
https://www.readbyqxmd.com/read/29751713/-chemical-constituents-from-roots-of-datura-metel
#17
Bing-You Yang, Chun-Li Yang, Yan Liu, Hai-Xue Kuang
The chemical constituents from the n-butanol fraction of the 70% ethanol extract of Datura metel roots were separated by silica gel and ODS chromatogram columns as well as preparative HPLC. On the basis of spectral data analysis, their structures were elucidated. Twenty-one compounds were obtained and their structures were identified as citroside A (1), coniferin (2), paeoniflorin (3), (6R,7E,9R)-9-hydroxy-4,7-megastigmadien-3-one 9-O-[α-L-arabin-opyranosyl-(l→6)-β-D-glucopyranoside] (4), (1R,7R,10R,11R)-12-hydroxyl anhuienosol (5), kaurane acid glycoside A (6), ent-2-oxo-15,16-dihydroxypimar-8(14)-en-16-O-β-glucopyranoside (7), ginsenoside Rg₁(8), ginsenoside Re (9), notoginsenosides R₁(10), N-butyl-O-β-D-fructofuranoside (11), salidroside (12), hexyl β-sophoroside (13), 2,6-dimethoxy-4-hydroxyphenol 1-glucoside (14), benzyl-O-β-D-xylopyranoxyl(1→6)-β-D-glucopyranoside (15), (Z)-3-hexenyl-O-α-L-arabinopyranosyl-(1→6)-β-D-glucopyranoside (16), N-[2-(3,4-dihydro-xyphenyl)-2-hydroxyethyl]-3-(4-methoxyphenyl) prop-2-enamide (17), cannabisin D (18), cannabisin E (19), melongenamide B (20), paprazine (21)...
April 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29748054/functional-and-anatomical-outcome-of-inside-out-technique-for-cholesteatoma-surgery
#18
Priyanka Chamoli, Chandra Veer Singh, Sheetal Radia, Anand K Shah
BACKGROUND: To study the efficacy of inside-out technique in completely eradicating the cholesteatoma from middle ear and mastoid, preservation of hearing & and quality of life post mastoidectomy with regards to recurrent discharge, wax, granulations. MATERIAL AND METHODS: Non-randomized, prospective, observational study performed at the Department of ENT in our hospital. In the study we included 100 patients presenting with chronic suppurative otitis media with cholesteatoma, they underwent inside out mastoidectomy and were followed up till the end of the study to evaluate the efficacy of inside out mastoidectomy in eradicating the disease from the middle ear cleft...
April 17, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29747249/-the-surgical-management-of-nasal-skull-base-schwannoma-under-endonasal-endoscope-a-retrospective-review-of-52-cases
#19
L Yang, W D Zhao, Q Liu, H K Zhang, D H Wang
Objective: To discuss the surgical technique and outcome of nasal skull base schwannoma treated under endonasal endoscope. Methods: Fifty-two patients with nasal skull base nonvestibular schwannoma were treated under endonasal endoscope from May 2006 to June 2017 in Shanghai E&ENT Hospital. Of the patients, there were 21 men and 31 women. The age of the patients ranged from 33 to 71 years.Schwannoma mainly came from trigeminal nerve.Clinical symptoms included facial numbness, facial pain, nasal obstruction, headache, hypopsia, diplopia and tinnitus...
April 7, 2018: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/29747245/undergraduate-ear-nose-and-throat-training-how-do-we-inspire-the-next-generation
#20
Bhavesh Vijay Tailor
Historically, ENT has been a very competitive surgical specialty. In recent years, the number of applicants to higher surgical ENT training has been in decline. This is not surprising, given that the proportion of foundation doctors directly entering specialty training has fallen from 71.3% in 2011 to 42.6% in 2017. If this continues, there is a real possibility of under-filling training posts, which would be a setback to the British Association of Otorhinolaryngologists (ENT-UK) recommendation for an expansion of the specialist workforce...
May 10, 2018: Clinical Otolaryngology
keyword
keyword
3180
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"