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JOURNAL ARTICLE
Ying-Chun Ma, Yang Xie, Limin Liao
BACKGROUND: Previous studies have indicated that creatinine (Cr)-based glomerular filtration rate (GFR) estimating equations - including the new Chronic Kidney Disease Epidemiology creatinine (CKD-EPIcr ) equation without race and the estimated glomerular filtration rate (eGFR) equation developed for the Chinese population - displayed suboptimal performance in patients with neurogenic lower urinary tract dysfunction (NLUTD), which limited their clinical application for detecting changes in GFR levels in all cohorts...
April 17, 2024: Clinical Nephrology
#2
REVIEW
LaTanya Lofton Hogue, Michael Kennelly
This article discusses the ideal neurogenic bladder management team for patients who have neurogenic lower urinary tract dysfunction (NLUTD). It emphasizes the importance of a diverse team, including urologists, physiatrists, neurologist and others, working collaboratively to prevent complications and enhance patient outcomes. Owing to the unique nuances of the various neurologic conditions and patterns of NLUTD dysfunction, the roles of different specialists in the interdisciplinary team are outlined. This article describes 3 team models: multidisciplinary, interdisciplinary, and transdisciplinary, highlighting the benefits of collaborative approaches...
May 2024: Urologic Clinics of North America
#3
REVIEW
Shanice Cox, Taiwo Dodo-Williams, Brandee Branche, Natalia García-Peñaloza, Mayra Lucas, Yahir Santiago-Lastra
The systematic review and workshop recommendations by the Neurogenic Bladder Research Group offer a comprehensive framework for evaluating health disparities in adult neurogenic lower urinary tract dysfunction (NLUTD). The study acknowledges the multifaceted nature of health, highlighting that medical care, though critical, is not the sole determinant of health outcomes. Social determinants of health significantly influence the disparities seen in NLUTD. This report calls for a shift in focus from traditional urologic care to a broader, more inclusive perspective that accounts for the complex interplay of social, economic, and health care factors in managing NLUTD...
May 2024: Urologic Clinics of North America
#4
REVIEW
Blayne Welk
The evaluation of people with neurogenic lower urinary tract dysfunction (NLUTD) often involves objective parameters, however quality of life (QOL) assessments are crucial for patient-centered care. This article discusses how to measure QOL and urinary symptoms in NLUTD and highlights various questionnaires such as the Qualiveen, Neurogenic Bladder Symptom Score (NBSS), and the Incontinence Quality of Life Questionnaire (I-QOL). These questionnaires focus on bladder-related QOL or symptoms and have been validated in multiple NLUTD populations...
May 2024: Urologic Clinics of North America
#5
JOURNAL ARTICLE
Yuan-Hong Jiang, Jia-Fong Jhang, Sheng-Fu Chen, Hann-Chorng Kuo
PURPOSE: Neurogenic lower urinary tract dysfunction (NLUTD) is common in patients with neurological lesions in the central nervous system (CNS). Medical treatment usually cannot adequately relieve NLUTD. This study reported the real-life treatment outcome of botulinum toxin A (BoNT-A) for overactive bladders (OAB) and voiding dysfunction in patients with CNS lesions. METHODS: We retrospectively analyzed the first-time treatment outcome of 74 patients who received detrusor 100 U BoNT-A for OAB and 45 patients who received a urethral sphincter 100 U BoNT-A injection for voiding dysfunction...
March 1, 2024: Toxins
#6
JOURNAL ARTICLE
Sandra Möhr, Saskia Fassbind, Brigitta Gahl, Hans-Helge Seifert, Kathrin Bausch
OBJECTIVE: The objective of this study is to investigate the incidence and risk factors for stone formation and recurrence in patients with neurogenic lower urinary tract dysfunction (NLUTD) in a real-world cohort. MATERIALS AND METHODS: A retrospective cohort study was conducted on all patients with NLUTD who underwent bladder stone treatment between 2010 and 2022. Univariate and multivariate Cox models were used to identify the potential risk factors for stone recurrence...
March 2024: BJUI compass
#7
JOURNAL ARTICLE
Blayne Welk, Jan Krhut, Radek Sýkora
INTRODUCTION: Our objective was to conduct an individual patient data meta-analysis (IPDMA) of the two published randomized placebo-controlled trials of mirabegron in people with neurogenic lower urinary tract dysfunction (NLUTD) due to spinal cord injury (SCI) or multiple sclerosis (MS). METHODS: We identified two randomized, placebo-controlled trials. We extracted individual patient data from the trials and evaluated two primary outcomes: change in maximum cystometric capacity and change in the patient perception of bladder condition (PPBC)...
March 13, 2024: Neurourology and Urodynamics
#8
JOURNAL ARTICLE
Lingfeng Meng, Zehao Yan, Xinhao Wang, Yaoguang Zhang, Zhikai Zhu, Wen Zhu, Qing Ling, Xiaoke Sun, Yinjun Gu, Jianwei Lv, Yan Li
BACKGROUND: Sacral neuromodulation (SNM) is an effective approach for treating lower urinary tract dysfunction (LUTD), and stimulation programming is essential for successful treatment. However, research on SNM programming for various indications is limited. Thus, we aimed to determine whether there were differences in the stimulation parameters for different SNM indications and the appropriate programming recommendations. MATERIALS AND METHODS: Clinical data were retrospectively collected from patients with LUTD who underwent SNM and completed internal pulse generator (IPG) implantation...
March 4, 2024: International Journal of Surgery
#9
JOURNAL ARTICLE
Rajbir Chaggar, Lance L Goetz, Jordan Adler, Mohammed B A Bhuiyan, Sean McAvoy, Jeffrey Tubbs
INTRODUCTION: Patients with spinal cord injuries/disorders (SCI/D) often suffer from bladder dysfunction, commonly referred to as neurogenic bladder or neurogenic lower urinary tract dysfunction (NLUTD). Standard urologic evaluation and management help to minimize complications such as vesicoureteral reflux, urinary tract infection, and nephrolithiasis. However, we have further encountered patients with more complex issues, such as chronic kidney disease (CKD), end-stage renal disease (ESRD), bilateral nephrectomies, and urinary diversion/augmentation surgeries...
March 4, 2024: Spinal Cord Series and Cases
#10
REVIEW
Desiree Vrijens, Harry Kendall, François Hervé
PURPOSE: Neurogenic stress urinary incontinence (N-SUI) is a condition with serious impact on the quality of life. There are several treatment modalities of which the artificial urinary sphincter (AUS) stands out as the most suitable technique for addressing sphincter insufficiency. In this article, the purpose is to describe practical considerations, outcomes, and complications of the artificial urinary sphincter in neurological sphincter deficiency in both males and females. METHODS: A narrative review of the current literature...
February 3, 2024: World Journal of Urology
#11
JOURNAL ARTICLE
Betsy H Salazar, Kristopher A Hoffman, John A Lincoln, Christof Karmonik, Hamida Rajab, Santosh A Helekar, Rose Khavari
BACKGROUND: Multiple Sclerosis (MS) is an often debilitating disease affecting the myelin sheath that encompasses neurons. It can be accompanied by a myriad of pathologies and adverse effects such as neurogenic lower urinary tract dysfunction (NLUTD). Current treatment modalities for resolving NLUTD focus mainly on alleviating symptoms while the source of the discomfort emanates from a disruption in brain to bladder neural circuitry. Here, we leverage functional magnetic resonance imaging (fMRI), repetitive transcranial magnetic stimulation (rTMS) protocols and the brains innate neural plasticity to aid in resolving overactive bladder (OAB) symptoms associated with NLUTD...
January 25, 2024: BMC Urology
#12
JOURNAL ARTICLE
Juliana Marin Fontes, Emmanuel Machado Oliveira, Tereza Cristina Monteiro de Melo Prazeres, Glaura Nisya de Oliveira Cruz, Marta Rizzini, Saulo Duarte Passos, Lilian Lira Lisboa, Grace Ferreira de Araújo, Valéria Azevedo de Almeida, Jociele Malacarne, Maria Emília de Domenico Garcia, Lilian Cagliari Linhares Barreto, Adriano Almeida Calado, Luciana Fernandes da Nóbrega, Maria Júlia Moura Nascimento Santos, Rafael Pauletti Gonçalves, Luana Farache, Maurício Feliciano da Silva, Fábio Valente Rizzo, Luiz Dias da Silva, Nilgicy Maria de Jesus Amorim, Hannah Cavalcante Guedes Pinheiro, Adriana Suely de Oliveira Melo, Fabiana de Oliveira Melo, Rômulo Dias Moreira, Benito Junior Santos da Costa, Melissa de Almeida Melo Maciel Mangueira, Margareth Catoia Varela, Lucia Maria Costa Monteiro
INTRODUCTION: Neurogenic bladder was first confirmed as a urological sequela of Congenital Zika Syndrome (CZS) in 2018. Further clinical-epidemiological evidence also confirmed neurogenic bowel dysfunction and cryptorchidism. To strengthen the care for these children, the Congenital Zika Virus Bladder and Bowel Sequelae Network (RASZ in Brazilian) was created, including six integrated centers in Brazil. This article represents the initial outcome of the efforts by RASZ. OBJECTIVE: To evaluate the prevalence of bladder and bowel dysfunction, cryptorchidism and other urological sequelae related to CZS in cohorts attended in six Brazilian states...
November 23, 2023: Journal of Pediatric Urology
#13
JOURNAL ARTICLE
Christopher Chapple, Paul Abrams, Thomas Lam, Altaf Mangera, Mohammed Belal, Carmel Curtis, Jacqueline Emkes, Sarah Hillery, Karen Irwin, Karen Logan, Polly Weston, Ann Yates
BACKGROUND: Clean intermittent self-catheterisation (CISC or ISC) is used by patients/carers to empty the bladder if needed. Sometimes the urethral lumen leading out of the bladder is blocked; sometimes, the bladder (detrusor) muscle itself or the autonomic motor nerves innervating the bladder are damaged, resulting in a failure of the detrusor muscle to work, leading to a failure of the bladder being able to empty adequately. Prior consensus as to the indications and timing of CISC has yet to be provided...
December 11, 2023: Neurourology and Urodynamics
#14
JOURNAL ARTICLE
Rochelle E Tractenberg, Suzanne L Groah, Jamie K Frost, Futoshi Yumoto, Amanda K Rounds, Inger H Ljungberg
OBJECTIVES: To determine whether assessment and decision-making around urinary symptoms in people with neurogenic lower urinary tract dysfunction (NLUTD) should depend on bladder management. METHODS: Three surveys of urinary symptoms associated with NLUTD (USQNBs) were designed specific to bladder management method for those who manage their bladders with indwelling catheter (IDC), intermittent catheter (IC), or voiding (V). Each was deployed one time to a national sample...
2023: Topics in Spinal Cord Injury Rehabilitation
#15
REVIEW
Sheng-Fu Chen, Hann-Chorng Kuo
The main problems of neurogenic lower urinary tract dysfunction (NLUTD) in patients with spinal cord injury (SCI) consist of impaired urine storage, impaired bladder emptying, or both. The priorities in the management of SCI-NLUTD should be preservation of renal function, followed by freedom from urinary tract infections and improvement of quality of life. Management of NLUTD in patients with SCI must be based on urodynamic findings rather than clinical evaluations. In the hospital without urodynamic equipment, careful measurement of intravesical pressure and safety functional bladder capacity in conjunction with clinical assessment are also feasible...
November 30, 2023: International Urology and Nephrology
#16
JOURNAL ARTICLE
Sakineh Hajebrahimi, Masoud Zeynalzadeh, Ashkan Shafigh, Helia Mostafaei, Moloud Balafar, Nima Naghdi, Hanieh Salehi-Pourmehr
OBJECTIVE: Patients suffering from multiple sclerosis (MS) frequently experience lower urinary tract (LUT) dysfunction, which significantly impacts their quality of life. This study's objective was to conduct a scientometric analysis of the literature on MS-induced neurogenic LUT dysfunction. METHODS: Using bibliometric methods, we examined the literature on neurogenic lower urinary tract dysfunction (NLUTD) in MS patients without restricting it to prevalence studies or specific management methods...
November 16, 2023: Urol Res Pract
#17
JOURNAL ARTICLE
Haider Abed, Magdy Hassouna, Nader Aldossary, Mary Mckibbon, Blayne Welk
INTRODUCTION: The Canadian Urological Association (CUA) neurogenic bladder guideline surveillance strategy for neurogenic lower urinary tract dysfunction (NLUTD) has not been formally evaluated. Our objective was to evaluate the validity of the risk stratification suggested in these guidelines. METHODS: This was a prospective, observational cohort study of adult NLUTD patients with spinal cord injury, multiple sclerosis, or spina bifida who required urodynamics...
August 29, 2023: Canadian Urological Association Journal
#18
JOURNAL ARTICLE
C Bouteille, M Pere, I Chelghaf, J Rigaud, F X Madec, M-A Perrouin-Verbe, T Loubersac
INTRODUCTION: Patients with neurologic bladder are at an increased risk for urolithiasis, and currently, data on mini-percutaneous nephrolithotomy in this population are limited. Our objective was to compare mini (15F)-percutaneous nephrolithotomy, standard (24F)-PCNL and flexible ureteroscopy in terms of efficacy and safety in treatment of kidney stones in patients with neurogenic lower urinary tract dysfunction (NLUTD). METHODS: We conducted a retrospective monocentric study in our neuro-urological referral centre...
September 25, 2023: Progrès en Urologie
#19
REVIEW
Matthew Playfair, Sean Elliott, Blayne Welk
PURPOSE: Improvements in life expectancy have resulted in an increasing number of adults with cerebral palsy, of which over a third will have neurogenic lower urinary tract dysfunction (NLUTD). This review explores urinary dysfunction in adults with cerebral palsy. METHODS: Relevant literature on NLUTD in adults with cerebral palsy was identified using an unrestricted search of PubMed. RESULTS: Urinary incontinence is the most common complaint, often accompanied by frequency and urgency...
November 2023: World Journal of Urology
#20
REVIEW
Sanjay Sinha
PURPOSE: Patients with neurogenic lower urinary tract dysfunction (nLUTD) can be at risk of preventable damage to the upper urinary tract (UUT), a risk that varies with the underlying diagnosis. Existing literature fails to document precisely which domains of UUT must be followed. This review focusses on surveillance of UUT with special emphasis on high-risk nLUTD. METHODS: Narrative review of available evidence and current global guidelines to identify patients of nLUTD at higher risk of UUT damage and to define each domain that needs to be followed...
November 2023: World Journal of Urology
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