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https://www.readbyqxmd.com/read/28618110/intravesical-vanilloids-for-treating-neurogenic-lower-urinary-tract-dysfunction-in-patients-with-multiple-sclerosis-a-systematic-review-and-meta-analysis-a-report-from-the-neuro-urology-promotion-committee-of-the-international-continence-society-ics
#1
REVIEW
Véronique Phé, Marc P Schneider, Benoit Peyronnet, Nadim Abo Youssef, Livio Mordasini, Emmanuel Chartier-Kastler, Lucas M Bachmann, Thomas M Kessler
AIMS: To systematically assess all available evidence on efficacy and safety of vanilloids for treating neurogenic lower urinary tract dysfunction (NLUTD) in patients with multiple sclerosis (MS). METHODS: This systematic review and meta-analysis was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Studies were identified by electronic search of Cochrane register, Embase, Medline, Scopus, (last search January 8, 2016)...
June 15, 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28444713/do-we-assess-urethral-function-adequately-in-lutd-and-nlutd-ici-rs-2015
#2
REVIEW
Jerzy B Gajewski, Peter F W M Rosier, Sajjad Rahnama'i, Paul Abrams
INTRODUCTION: Urethral function, as well as anatomy, play a significant role in voiding reflex and abnormalities in one or both contribute to the pathophysiology of Lower Urinary Tract Dysfunction (LUTD). We have several diagnostic tools to assess the urethral function or dysfunction but the question remains, are these adequate? METHODS: This is a report of the proceedings of Think Tank P1: 'Do we assess urethral function adequately in LUTD and NLUTD?' from the annual International Consultation on Incontinence-Research Society, which took place September 22-24, 2014 in Bristol, UK...
April 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/28367674/high-edss-can-predict-risk-for-upper-urinary-tract-damage-in-patients-with-multiple-sclerosis
#3
Benjamin V Ineichen, Marc P Schneider, Martin Hlavica, Niels Hagenbuch, Michael Linnebank, Thomas M Kessler
BACKGROUND: Neurogenic lower urinary tract dysfunction (NLUTD) is very common in patients with multiple sclerosis (MS), and it might jeopardize renal function and thereby increase mortality. Although there are well-known urodynamic risk factors for upper urinary tract damage, no clinical prediction parameters are available. OBJECTIVE: We aimed to assess clinical parameters potentially predicting urodynamic risk factors for upper urinary tract damage. METHODS: A consecutive series of 141 patients with MS referred from neurologists for primary neuro-urological work-up including urodynamics were prospectively evaluated...
March 1, 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/28314966/-neuro-urological-diagnosis-and-therapy-of-lower-urinary-tract-dysfunction-in-patients-with-spinal-cord-injury-s2k-guideline-of-the-german-speaking-medical-society-of-paraplegia-dmgp-awmf-register-no-179-001
#4
R Böthig, B Domurath, A Kaufmann, J Bremer, W Vance, I Kurze
BACKGROUND: Most patients with spinal cord injury (SCI) suffer from neurogenic lower urinary tract dysfunction (NLUTD), bowel dysfunction and sexual dysfunction. If these remain untreated, severe medical complications and serious limitations (restrictions) in quality of life are imminent. OBJECTIVES: In the long term, there are considerable differences in the treatment results of highly specialized centers versus other treatment facilities. MATERIALS AND METHODS: Against this background, a consensus-based guideline, according to the AWMF (Association of the Scientific Medical Societies in Germany) criteria (S2k), was developed by the neuro-urology working group of the DMPG (German-Speaking Medical Society of Paraplegia)...
March 17, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28212120/neurogenic-voiding-dysfunction
#5
Petros Georgopoulos, Apostolos Apostolidis
PURPOSE OF REVIEW: This review aims to analyze and discuss all recently published articles associated with neurogenic voiding discussion providing readers with the most updated knowledge and trigger for further research. RECENT FINDINGS: They include the proposal of a novel classification system for the pathophysiology of neurogenic lower urinary tract dysfunction (NLUTD) which combines neurological defect in a distinct anatomic location, and data on bowel dysfunction, autonomic dysreflexia and urine biomarkers; review of patient-reported outcome measures in NLUTD; review of the criteria for the diagnosis of clinically significant urinary infections; novel research findings on the pathophysiology of NLUTD; and review of data on minimally and more invasive treatments...
May 2017: Current Opinion in Urology
https://www.readbyqxmd.com/read/28058780/cannabinoids-for-treating-neurogenic-lower-urinary-tract-dysfunction-in-patients-with-multiple-sclerosis-a-systematic-review-and-meta-analysis
#6
REVIEW
Nadim Abo Youssef, Marc P Schneider, Livio Mordasini, Benjamin V Ineichen, Lucas M Bachmann, Emmanuel Chartier-Kastler, Jalesh N Panicker, Thomas M Kessler
OBJECTIVES: To review systematically all the available evidence on efficacy and safety of cannabinoids for treating neurogenic lower urinary tract dysfunction (NLUTD) in patients with multiple sclerosis (MS). PATIENTS AND METHODS: The review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Studies were identified by electronic search of the Cochrane register, Embase, Medline, Scopus (last search on 11 November 2016)...
April 2017: BJU International
https://www.readbyqxmd.com/read/27725995/-objective-and-subjective-requirement-of-aids-and-appliances-in-patients-with-neurogenic-lower-urinary-tract-dysfunction-multicenter-study-to-determinate-the-daily-necessity-of-urological-aids-and-appliances
#7
MULTICENTER STUDY
J Bremer, R Böthig, B Domurath, J Kutzenberger, A Kaufmann, J Pretzer, J P Klask, V Geng, W Vance, I Kurze
BACKGROUND: The provision of urological appliances for patients with neurogenic lower urinary tract dysfunction (NLUTD) is essential. Hitherto existing standard guidelines for the estimation of monthly material requirements are based solely on estimates. OBJECTIVE: The goal of this work was to define the objective and subsequently subjective requirements for urological appliances on a scientifically validated basis. MATERIALS AND METHODS: Data concerning bladder management and daily consumption of urological appliances for patients with NLUTD were collected through a standardized survey at six different centers in Germany during the period of October to December 2014 and statistically evaluated...
December 2016: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/27664581/functional-magnetic-resonance-imaging-with-concurrent-urodynamic-testing-identifies-brain-structures-involved-in-micturition-cycle-in-patients-with-multiple-sclerosis
#8
Rose Khavari, Christof Karmonik, Michael Shy, Sophie Fletcher, Timothy Boone
PURPOSE: Neurogenic lower urinary tract dysfunction, which is common in patients with multiple sclerosis, has a significant impact on quality of life. In this study we sought to determine brain activity processes during the micturition cycle in female patients with multiple sclerosis and neurogenic lower urinary tract dysfunction. MATERIALS AND METHODS: We report brain activity on functional magnetic resonance imaging and simultaneous urodynamic testing in 23 ambulatory female patients with multiple sclerosis...
February 2017: Journal of Urology
https://www.readbyqxmd.com/read/27596481/preserved-micturition-after-intradetrusor-onabotulinumtoxina-injection-for-treatment-of-neurogenic-bladder-dysfunction-in-parkinson-s-disease
#9
Stephanie C Knüpfer, Susanne A Schneider, Mareike M Averhoff, Carsten M Naumann, Günther Deuschl, Klaus-Peter Jünemann, Moritz F Hamann
BACKGROUND: To assess the efficacy and safety of intradetrusor onabotulinumtoxinA (OnabotA) injection treatment in patients with neurogenic lower urinary tract dysfunction (NLUTD), especially for patients with Parkinson disease (PD). METHODS: PD patients refractory to oral antimuscarinic participated in an off-label use study and were evaluated prior and after 200 IU OnabotA injection into detrusor muscle, including trigone. Changes due to treatment were evaluated using bladder diaries, urodynamics, and questionnaires...
September 5, 2016: BMC Urology
https://www.readbyqxmd.com/read/26950046/nerve-growth-factor-does-not-seem-to-be-a-biomarker-for-neurogenic-lower-urinary-tract-dysfunction-after-spinal-cord-injury
#10
Jörg Krebs, David Pavlicek, Jivko Stoyanov, Jürgen Pannek, Jens Wöllner
AIM: To prospectively investigate the association of bladder function with the nerve growth factor (NGF) concentration in the urine of individuals with neurogenic lower urinary tract dysfunction (NLUTD) after spinal cord injury (SCI). METHODS: Individuals with chronic SCI and NLUTD presenting for a routine urologic examination at a tertiary urologic referral center were recruited for the study. Patient characteristics, the current bladder evacuation method and urodynamic parameters were collected...
March 2017: Neurourology and Urodynamics
https://www.readbyqxmd.com/read/26765476/patients-with-neurogenic-lower-urinary-tract-dysfunction-following-spinal-cord-injury-are-at-increased-risk-of-developing-type-2-diabetes-mellitus-a-population-based-cohort-study
#11
Wei-Chih Lien, Ta-Shen Kuan, Yu-Ching Lin, Fu-Wen Liang, Pei-Chun Hsieh, Chung-Yi Li
To investigate whether patients with neurogenic lower urinary tract dysfunction (NLUTD) following spinal cord injury (SCI) are at increased risk of developing type 2 diabetes mellitus (T2DM).The retrospective cohort study used a subset of the Taiwan National Health Insurance Research Database (NHIRD) comprising information on 2 million beneficiaries randomly sampled from the general population. A total of 3515 patients with newly diagnosed SCI were identified during the period of 2001 to 2008. Among them, 170 developed NLUTD following SCI...
January 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/26620878/risk-factors-for-symptomatic-urinary-tract-infections-in-individuals-with-chronic-neurogenic-lower-urinary-tract-dysfunction
#12
J Krebs, J Wöllner, J Pannek
STUDY DESIGN: Retrospective investigation. OBJECTIVES: To investigate the association of patient and injury characteristics, as well as bladder management, with the occurrence of patient-reported, symptomatic urinary tract infection(s) UTI(s) in patients with chronic neurogenic lower urinary tract dysfunction (NLUTD). SETTING: Tertiary urologic referral center. METHODS: The patient database was screened for patients with chronic (>12 months) NLUTD who had presented between 2008 and 2012...
September 2016: Spinal Cord
https://www.readbyqxmd.com/read/26554274/bladder-management-in-individuals-with-chronic-neurogenic-lower-urinary-tract-dysfunction
#13
J Krebs, J Wöllner, J Pannek
STUDY DESIGN: Retrospective investigation. OBJECTIVES: To investigate the association of patient and injury characteristics with bladder evacuation by indwelling catheterization in patients with chronic neurogenic lower urinary tract dysfunction (NLUTD). SETTING: Tertiary urologic referral center. METHODS: The patient database was screened for patients with chronic (>12 months) NLUTD. Patient characteristics and bladder management details were collected...
August 2016: Spinal Cord
https://www.readbyqxmd.com/read/26513149/do-we-need-surveillance-urethro-cystoscopy-in-patients-with-neurogenic-lower-urinary-tract-dysfunction
#14
Ulla Sammer, Matthias Walter, Stephanie C Knüpfer, Ulrich Mehnert, Beata Bode-Lesniewska, Thomas M Kessler
PURPOSE: To examine the value of surveillance urethro-cystoscopy in patients with neurogenic lower urinary tract dysfunction (NLUTD) in regard to the conflicting literature as it is generally agreed that patients with NLUTD are at increased risk for bladder cancer. MATERIALS AND METHODS: In a cross-sectional study, a consecutive series of 129 patients (50 females, 79 males, mean age 51, range 18-88) suffering from NLUTD for at least 5 years was prospectively investigated using urethro-cystoscopy and bladder washing cytology at a single university spinal cord injury (SCI) center...
2015: PloS One
https://www.readbyqxmd.com/read/26503222/initial-experience-with-the-treatment-of-neurogenic-detrusor-overactivity-with-a-new-%C3%AE-3-agonist-mirabegron-in-patients-with-spinal-cord-injury
#15
J Wöllner, J Pannek
STUDY DESIGN: It is a retrospective chart analysis. OBJECTIVES: In patients with neurogenic lower urinary tract dysfunction (NLUTD) due to spinal cord injury (SCI), neurogenic detrusor overactivity (NDO) can cause both deterioration of the upper urinary tract and urinary incontinence. Antimuscarinic treatment is frequently discontinued due to side effects or lack of efficacy, whereas injection of onabotulinumtoxin into the detrusor is a minimally invasive procedure with risks of urinary retention, infection and haematuria...
January 2016: Spinal Cord
https://www.readbyqxmd.com/read/26446581/bladder-emptying-methods-neurogenic-lower-urinary-tract-dysfunction-and-impact-on-quality-of-life-in-people-with-long-term-spinal-cord-injury
#16
Jacinthe J E Adriaansen, Floris W A van Asbeck, Marga Tepper, Willemijn X Faber, Johanna M A Visser-Meily, Laetitia M O de Kort, Marcel W M Post
OBJECTIVES: To describe bladder-emptying methods used by people with long-term spinal cord injury (SCI) and to determine usage differences in relation to time since injury, sex, lesion level and completeness of lesion. Furthermore, to evaluate the relationship between bladder-emptying methods and the impact of neurogenic lower urinary tract dysfunction (NLUTD) on quality of life (QoL). DESIGN: Cross-sectional multicenter study. SETTING: Dutch community...
January 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/26266405/evaluation-and-management-of-neurogenic-bladder-what-is-new-in-china
#17
REVIEW
Limin Liao
Neurogenic bladder (NB) or neurogenic lower urinary tract dysfunction (NLUTD), a dysfunction of the urinary bladder and urethra due to disease of the central nervous system or peripheral nerves, is a major global medical and social problem. Numerous nervous system abnormalities, such as: stroke, Alzheimer's and Parkinson's diseases, traumatic spinal cord injury, spinal cord tumors, congenital spina bifida, and diabetes, can cause NB/NLUTD. There are two major types of bladder control problems associated with NB/NLUTD: the bladder becomes either overactive or underactive depending on the nature, level, and extent of nerve damage...
2015: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/26215913/sacral-neuromodulation-in-patients-with-neurogenic-lower-urinary-tract-dysfunction
#18
J Wöllner, J Krebs, J Pannek
STUDY DESIGN: This is a retrospective chart analysis. OBJECTIVES: The objective of this study was to evaluate the effect of sacral neuromodulation (SNM) in patients with neurogenic lower urinary tract dysfunction (NLUTD). SETTINGS: This study was conducted in a spinal cord injury rehabilitation center in Switzerland. METHODS: The charts of all patients who underwent SNM (testing and/or permanent implantation) because of NLUTD at our institution between 2007 and 2013 were evaluated...
February 2016: Spinal Cord
https://www.readbyqxmd.com/read/26194043/tibial-nerve-stimulation-for-treating-neurogenic-lower-urinary-tract-dysfunction-a-systematic-review
#19
REVIEW
Marc P Schneider, Tobias Gross, Lucas M Bachmann, Bertil F M Blok, David Castro-Diaz, Giulio Del Popolo, Jan Groen, Rizwan Hamid, Gilles Karsenty, Jürgen Pannek, Lisette 't Hoen, Thomas M Kessler
CONTEXT: Tibial nerve stimulation (TNS) is a promising therapy for non-neurogenic lower urinary tract dysfunction and might also be a valuable option for patients with an underlying neurological disorder. OBJECTIVE: We systematically reviewed all available evidence on the efficacy and safety of TNS for treating neurogenic lower urinary tract dysfunction (NLUTD). EVIDENCE ACQUISITION: The review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Statement...
November 2015: European Urology
https://www.readbyqxmd.com/read/26055644/autonomic-dysreflexia-and-repeatability-of-cardiovascular-changes-during-same-session-repeat-urodynamic-investigation-in-women-with-spinal-cord-injury
#20
Matthias Walter, Stephanie C Knüpfer, Lorenz Leitner, Ulrich Mehnert, Martin Schubert, Armin Curt, Thomas M Kessler
PURPOSE: To investigate autonomic dysreflexia (AD) and repeatability of cardiovascular changes during same session repeat urodynamic investigation (UDI) in women with spinal cord injury (SCI). METHODS: Prospective investigation of 33 consecutive women with suprasacral SCI suffering from neurogenic lower urinary tract dysfunction (NLUTD) undergoing same session repeat UDI and synchronous continuous cardiovascular monitoring [systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate (HR)]...
March 2016: World Journal of Urology
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