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Interventional cardiology

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https://www.readbyqxmd.com/read/29902265/clinical-use-of-submaximal-treadmill-exercise-testing-and-assessments-of-cardiac-biomarkers-nt-probnp-and-ctni-in-dogs-with-presymptomatic-mitral-regurgitation
#1
Leona Wall, Annika Mohr, Florenza Lüder Ripoli, Nayeli Schulze, Camila Duarte Penter, StephanOscar Hungerbuehler, Jan-Peter Bach, Karin Lucas, Ingo Nolte
Exercise intolerance is the first symptom of heart disease. Yet an objective and standardised method in canine cardiology to assess exercise capacity in a clinical setting is lacking. In contrast, exercise testing is a powerful diagnostic tool in humans, providing valuable information on prognosis and impact of therapeutic intervention. To investigate whether an exercise test reveals differences between dogs with early stage mitral regurgitation (MR) and dogs without cardiac disease, 12 healthy beagles (healthy group, HG) and 12 dogs with presymptomatic MR (CHIEF B1 / B2, patient group, PG) underwent a six-stage submaximal exercise test (ET) on a motorised treadmill...
2018: PloS One
https://www.readbyqxmd.com/read/29900163/is-decellularized-porcine-small-intestine-sub-mucosa-patch-suitable-for-aortic-arch-repair
#2
Antonio F Corno, Paul Smith, Laurynas Bezuska, Branko Mimic
Introduction: We reviewed our experience with decellularized porcine small intestine sub-mucosa (DPSIS) patch, recently introduced for congenital heart defects. Materials and Methods: Between 10/2011 and 04/2016 a DPSIS patch was used in 51 patients, median age 1.1 months (5 days to 14.5 years), for aortic arch reconstruction (45/51 = 88.2%) or aortic coarctation repair (6/51 = 11.8%). All medical records were retrospectively reviewed, with primary endpoints interventional procedure (balloon dilatation) or surgery (DPSIS patch replacement) due to patch-related complications...
2018: Frontiers in Pediatrics
https://www.readbyqxmd.com/read/29898219/association-of-patient-perceptions-of-cardiovascular-risk-and-beliefs-on-statin-drugs-with-racial-differences-in-statin-use-insights-from-the-patient-and-provider-assessment-of-lipid-management-registry
#3
Michael G Nanna, Ann Marie Navar, Pearl Zakroysky, Qun Xiang, Anne C Goldberg, Jennifer Robinson, Veronique L Roger, Salim S Virani, Peter W F Wilson, Joseph Elassal, L Veronica Lee, Tracy Y Wang, Eric D Peterson
Importance: African American individuals face higher atherosclerotic cardiovascular disease risk than white individuals; reasons for these differences, including potential differences in patient beliefs regarding preventive care, remain unknown. Objective: To evaluate differences in statin use between white and African American patients and identify the potential causes for any observed differences. Design, Setting, and Participants: Using the 2015 Patient and Provider Assessment of Lipid Management (PALM) Registry data, we compared statin use and dosing between African American and white outpatient adults who were potentially eligible for primary or secondary prevention statins...
June 13, 2018: JAMA Cardiology
https://www.readbyqxmd.com/read/29898046/percutaneous-coronary-intervention-in-chronic-total-occlusion
#4
Luiz Fernando Ybarra, Marcelo J C Cantarelli, Viviana M G Lemke, Alexandre Schaan de Quadros
Percutaneous coronary intervention in chronic total occlusion is a rapidly evolving area, being considered the last frontier of interventional cardiology. In recent years, the development of new techniques and equipment, as well as the training of specialized personnel, increased their success rates, making it the most predictable procedure available. Although the number of randomized and controlled studies is still limited, results from large multicentered registries allow us to safely offer this intervention to patients, as another treatment option along with the optimized drug treatment and myocardial revascularization surgery...
May 2018: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/29895759/classical-risk-factors-and-inflammatory-biomarkers-one-of-the-missing-biological-links-between-cardiovascular-disease-and-major-depressive-disorder
#5
Thomas C Baghai, Gabriella Varallo-Bedarida, Christoph Born, Sibylle Häfner, Cornelius Schüle, Daniela Eser, Peter Zill, André Manook, Johannes Weigl, Somayeh Jooyandeh, Caroline Nothdurfter, Clemens von Schacky, Brigitta Bondy, Rainer Rupprecht
BACKGROUND: Cardiovascular disorders (CVD) and major depressive disorder (MDD) are the most frequent diseases worldwide responsible for premature death and disability. Behavioral and immunological variables influence the pathophysiology of both disorders. We therefore determined frequency and severity of MDD in CVD and studied whether MDD without CVD or other somatic diseases influences classical and inflammatory biomarkers of cardiovascular risk. In addition, we investigated the influence of proinflammatory cytokines on antidepressant treatment outcome...
June 12, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29895713/impact-of-coronary-lesion-geometry-on-fractional-flow-reserve-data-from-interventional-cardiology-research-in-cooperation-society-fractional-flow-reserve-and-intravascular-ultrasound-registry
#6
Do-Yoon Kang, Jung-Min Ahn, Young Woo Kim, Ji Young Moon, Joon Sang Lee, Bon-Kwon Koo, Pil Hyung Lee, Duk-Woo Park, Soo-Jin Kang, Seung-Whan Lee, Young-Hak Kim, Seong-Wook Park, Seung-Jung Park
BACKGROUND: The impact of various coronary lesion geometries on fractional flow reserve (FFR) is poorly understood. METHODS AND RESULTS: A total of 1552 coronary lesions in 1236 patients from a prospective Interventional Cardiology Research In-cooperation Society Fractional Flow Reserve and Intravascular Ultrasound registry were assessed using quantitative coronary angiography, intravascular ultrasound, and FFR. Computational fluid dynamics simulation was performed for theoretical validation...
June 2018: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29892472/pharmacological-interventions-effective-in-improving-exercise-capacity-in-heart-failure
#7
REVIEW
Cristiana Vitale, Spoletini Ilaria, Giuseppe Mc Rosano
Heart failure (HF) is characterised by exercise intolerance, which substantially impairs quality of life (QOL) and prognosis. The aim of this review is to summarise the state of the art on pharmacological interventions that are able to improve exercise capacity in HF. Ivabradine, trimetazidine and intravenous iron are the only drugs included in the European Society of Cardiology HF guidelines that have consistently been shown to positively affect functional capacity in HF. The beneficial effects on HF symptoms, physical performance and QOL using these pharmacological approaches are described...
May 2018: Cardiac Failure Review
https://www.readbyqxmd.com/read/29888611/trimetazidine-in-the-prevention-of-tissue-ischemic-conditions
#8
Manolis S Kallistratos, Leonidas E Poulimenos, Sofia Giannitsi, Pavlos Tsinivizov, Athanasios J Manolis
Trimetazidine (TMZ) is a metabolic agent with significant anti-ischemic properties. By inhibiting the terminal enzyme in the β-oxidation pathway, it shifts the energy substrate metabolism, enhancing glucose metabolism. Thus, it maintains the required energy production with less oxygen consumption, an effect necessary in cases of myocardi. Trimetazidine was recently reaccredited as add-on therapy for symptomatic treatment in patients with stable angina, not adequately controlled or intolerant to first-line therapy...
January 1, 2018: Angiology
https://www.readbyqxmd.com/read/29887180/perioperative-and-periprocedural-management-of-antithrombotic-therapy-consensus-document-of-sec-sedar-seacv-sectcv-aec-secpre-sepd-sego-sehh-seth-semergen-semfyc-semg-semicyuc-semi-semes-separ-senec-seo-sepa-servei-secot-and-aeu
#9
David Vivas, Inmaculada Roldán, Raquel Ferrandis, Francisco Marín, Vanessa Roldán, Antonio Tello-Montoliu, Juan Miguel Ruiz-Nodar, Juan José Gómez-Doblas, Alfonso Martín, Juan Vicente Llau, María José Ramos-Gallo, Rafael Muñoz, Juan Ignacio Arcelus, Francisco Leyva, Fernando Alberca, Raquel Oliva, Ana María Gómez, Carmen Montero, Fuat Arikan, Luis Ley, Enrique Santos-Bueso, Elena Figuero, Antonio Bujaldón, José Urbano, Rafael Otero, Juan Francisco Hermida, Isabel Egocheaga, José Luis Llisterri, José María Lobos, Ainhoa Serrano, Olga Madridano, José Luis Ferreiro
During the last few years, the number of patients receiving anticoagulant and antiplatelet therapy has increased worldwide. Since this is a chronic treatment, patients receiving it can be expected to need some kind of surgery or intervention during their lifetime that may require treatment discontinuation. The decision to withdraw antithrombotic therapy depends on the patient's thrombotic risk versus hemorrhagic risk. Assessment of both factors will show the precise management of anticoagulant and antiplatelet therapy in these scenarios...
June 7, 2018: Revista Española de Cardiología
https://www.readbyqxmd.com/read/29886608/-prenatal-interventional-therapy-in-two-cases-with-critical-pulmonary-stenosis-or-pulmonary-atresia-with-intact-ventricular-septum
#10
C C Pang, W Pan, Z W Zhang, C B Zhou, Y F Li, X Zhang, F Z Han, Y X Sun, S Wang, J Zhuang
Objectives: Two cases who underwent fetal pulmonary valvuloplasty (FPV) for pulmonary atresia with intact ventricular septum (PA-IVS) or critical pulmonary stenosis with intact ventricular septum (CPS-IVS) successfully were reported. The aim of the report was to explore the criteria for case selection, the technical essentials of FPV, and the postpartum outcome of the fetus. Methods: One case with PA-IVS and the other with CPS-IVS were enrolled in September 2016 and February 2017 in Guangdong General Hospital, and both cases were diagnosed with severe right ventricular dysplasia and tricuspid regurgitation by fetal echocardiogram...
June 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29884916/vascular-access-related-complications-in-women-temporal-trends-emerging-data-and-the-current-state-of-interventional-cardiology-practice
#11
REVIEW
Yohan Chacko, Rushi V Parikh, Jennifer A Tremmel
Women undergoing cardiac catheterization, percutaneous coronary intervention, transcatheter aortic valve replacement, and other structural heart interventions have a significantly higher risk of vascular complications and bleeding than men, leading to significant morbidity and mortality. This review highlights the importance of recognizing female sex as a specific and independent risk factor, and focuses on mechanisms of increased risk and strategies to minimize that risk. Smaller caliber peripheral vessels, low body weight, variations in platelet reactivity, and inappropriate dosing of anticoagulant and antiplatelet agents are the currently identified mechanisms for elevated bleeding and vascular complication risk in women...
June 8, 2018: Current Atherosclerosis Reports
https://www.readbyqxmd.com/read/29880501/sleep-apnea-and-cardiovascular-disease-an-enigmatic-risk-factor
#12
REVIEW
John S Floras
Synchronization of molecular, metabolic, and cardiovascular circadian oscillations is fundamental to human health. Sleep-disordered breathing, which disrupts such temporal congruence, elicits hemodynamic, autonomic, chemical, and inflammatory disturbances with acute and long-term consequences for heart, brain, and circulatory and metabolic function. Sleep apnea afflicts a substantial proportion of adult men and women but is more prevalent in those with established cardiovascular diseases and especially fluid-retaining states...
June 8, 2018: Circulation Research
https://www.readbyqxmd.com/read/29873511/determinants-of-participation-and-risk-factor-control-according-to-attendance-in-cardiac-rehabilitation-programmes-in-coronary-patients-in-europe-euroaspire-iv-survey
#13
Kornelia Kotseva, David Wood, Dirk De Bacquer
Aim The purpose of this study was to describe the proportions of patients referred to and attending cardiac rehabilitation programmes in Europe and to compare lifestyle and risk factor targets achieved according to participation in a cardiac rehabilitation programme. Methods The EUROASPIRE IV cross-sectional survey was undertaken in 78 centres from 24 European countries. Consecutive patients aged <80 years with acute coronary syndromes and/or revascularization procedures were interviewed at least six months after their event...
January 1, 2018: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/29868614/interventional-cardio-oncology-adding-a-new-dimension-to-the-cardio-oncology-field
#14
Victor Y Liu, Ali M Agha, Juan Lopez-Mattei, Nicolas Palaskas, Peter Kim, Kara Thompson, Elie Mouhayar, Konstantinos Marmagkiolis, Saamir A Hassan, Kaveh Karimzad, Cezar A Iliescu
The management of cardiovascular disease in patients with active cancer presents a unique challenge in interventional cardiology. Cancer patients often suffer from significant comorbidities such as thrombocytopenia and coagulopathic and/or hypercoagulable states, which complicates invasive evaluation and can specifically be associated with an increased risk for vascular access complications. Furthermore, anticancer therapies cause injury to the vascular endothelium as well as the myocardium. Meanwhile, improvements in diagnosis and treatment of various cancers have contributed to an increase in overall survival rates in cancer patients...
2018: Frontiers in Cardiovascular Medicine
https://www.readbyqxmd.com/read/29867293/consensus-document-anmco-ance-arca-gicr-iacpr-gise-sicoa-long-term-antiplatelet-therapy-in-patients-with-coronary-artery-disease
#15
Michele Massimo Gulizia, Furio Colivicchi, Maurizio Giuseppe Abrignani, Marco Ambrosetti, Nadia Aspromonte, Gabriella Barile, Roberto Caporale, Giancarlo Casolo, Emilia Chiuini, Andrea Di Lenarda, Pompilio Faggiano, Domenico Gabrielli, Giovanna Geraci, Alessio Gaetano La Manna, Aldo Pietro Maggioni, Alfredo Marchese, Ferdinando Maria Massari, Gian Francesco Mureddu, Giuseppe Musumeci, Federico Nardi, Antonio Vittorio Panno, Roberto Franco Enrico Pedretti, Massimo Piredda, Enrico Pusineri, Carmine Riccio, Roberta Rossini, Fortunato Scotto di Uccio, Stefano Urbinati, Ferdinando Varbella, Giovanni Battista Zito, Leonardo De Luca
Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 receptor inhibitor is the cornerstone of pharmacologic management of patients with acute coronary syndrome (ACS) and/or those receiving coronary stents. Long-term (>1 year) DAPT may further reduce the risk of stent thrombosis after a percutaneous coronary intervention (PCI) and may decrease the occurrence of non-stent-related ischaemic events in patients with ACS. Nevertheless, compared with aspirin alone, extended use of aspirin plus a P2Y12 receptor inhibitor may increase the risk of bleeding events that have been strongly linked to adverse outcomes including recurrent ischaemia, repeat hospitalisation and death...
May 2018: European Heart Journal Supplements: Journal of the European Society of Cardiology
https://www.readbyqxmd.com/read/29860706/identification-of-variables-influencing-pharmaceutical-interventions-to-improve-medication-review-efficiency
#16
Lauriane Cornuault, Victorine Mouchel, Thuy-Tan Phan Thi, Hélène Beaussier, Yvonnick Bézie, Jennifer Corny
Background Clinical pharmacists' involvement has improved patients' care, by suggesting therapeutic optimizations. However, budget restrictions require a prioritization of these activities to focus resources on patients more at risk of medication errors. Objective The aim of our study was to identify variables influencing the formulation of pharmaceutical to improve medication review efficiency. Setting This study was conducted in medical wards of a 643-acute beds hospital in Paris, France. Methods All hospital medical prescriptions of all patients admitted within four medical wards (cardiology, rheumatology, neurology, vascular medicine) were analyzed...
June 2, 2018: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/29850526/machine-learning-augmented-propensity-score-adjusted-multilevel-mixed-effects-panel-analysis-of-hands-on-cooking-and-nutrition-education-versus-traditional-curriculum-for-medical-students-as-preventive-cardiology-multisite-cohort-study-of-3-248-trainees-over
#17
Dominique J Monlezun, Lyn Dart, Anne Vanbeber, Peggy Smith-Barbaro, Vanessa Costilla, Charlotte Samuel, Carol A Terregino, Emine Ercikan Abali, Beth Dollinger, Nicole Baumgartner, Nicholas Kramer, Alex Seelochan, Sabira Taher, Mark Deutchman, Meredith Evans, Robert B Ellis, Sonia Oyola, Geeta Maker-Clark, Tomi Dreibelbis, Isadore Budnick, David Tran, Nicole DeValle, Rachel Shepard, Erika Chow, Christine Petrin, Alexander Razavi, Casey McGowan, Austin Grant, Mackenzie Bird, Connor Carry, Glynis McGowan, Colleen McCullough, Casey M Berman, Kerri Dotson, Tianhua Niu, Leah Sarris, Timothy S Harlan, On Behalf Of The Chop Co-Investigators
Background: Cardiovascular disease (CVD) annually claims more lives and costs more dollars than any other disease globally amid widening health disparities, despite the known significant reductions in this burden by low cost dietary changes. The world's first medical school-based teaching kitchen therefore launched CHOP-Medical Students as the largest known multisite cohort study of hands-on cooking and nutrition education versus traditional curriculum for medical students. Methods: This analysis provides a novel integration of artificial intelligence-based machine learning (ML) with causal inference statistics...
2018: BioMed Research International
https://www.readbyqxmd.com/read/29850267/should-de-winter-t-wave-electrocardiography-pattern-be-treated-as-st-segment-elevation-myocardial-infarction-equivalent-with-consequent-reperfusion-a-dilemmatic-experience-in-rural-area-of-indonesia
#18
Raymond Pranata, Ian Huang, Vito Damay
Background: Although de Winter T-wave electrocardiography pattern is rare, it signifies proximal left anterior descending artery occlusion and is often unrecognized by physicians. The aim of this case report was to highlight the dilemma in the management of a patient with de Winter T-wave pattern in the hospital without interventional cardiology facility. Case Presentation: A 65-year-old male presented with typical chest pain since 2 hours before admission, and ECG showed sinus rhythm of 57 bpm and >1 mm upsloping ST depression with symmetric tall T in lead V2-3 characteristic of de Winter T-wave ECG pattern...
2018: Case Reports in Cardiology
https://www.readbyqxmd.com/read/29850264/complex-recanalization-of-chronic-total-occluison-supported-by-minimal-extracorporeal-circulation-in-a-patient-with-an-aortic-valve-bioprothesis-in-extraanatomic-position
#19
Ruben Jansen, Brigitte Bathgate, Alexander Bufe, Jan-Erik Guelker
Percutaneous coronary intervention (PCI) of chronic total occlusion (CTO) still remains a major challenge in interventional cardiology. This case describes a complex PCI of the left main coronary artery and of a CTO of the right coronary artery using a minimal extracorporeal circulation system (MECC) in a patient with an aortic valve bioprothesis in extraanatomic position. It illustrates that complex recanalization strategies can be solved combining it with mechanical circulatory support technologies.
2018: Case Reports in Cardiology
https://www.readbyqxmd.com/read/29850228/radiation-dose-optimization-in-interventional-cardiology-a-teaching-hospital-experience
#20
M K Badawy, T Clark, D Carrion, P Deb, O Farouque
Radiological interventions play an increasingly relevant role in cardiology. Due to the inherent risks of ionizing radiation, proper care must be taken with monitoring and optimizing the dose delivered in angiograms to pose as low risk as possible to staff and patients. Dose optimization is particularly pertinent in teaching hospitals, where longer procedure times are at times necessary to accommodate the teaching needs of junior staff, and thus impart a more significant radiation dose. This study aims to analyze the effects of different protocol settings in routine coronary angiograms, from the perspective of a large tertiary center implementing a rapid dose reduction program...
2018: Cardiology Research and Practice
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