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https://www.readbyqxmd.com/read/29054434/associations-between-single-nucleotide-polymorphisms-in-the-ntrk1-gene-and-basal-pain-sensitivity-in-young-han-chinese-women
#1
Ningbo Li, Guangyou Duan, Jiaoli Sun, Shanna Guo, Qingli Wang, Hua Zheng, Cong Wang, Changmao Zhu, Yi Liu, Xianwei Zhang
OBJECTIVES: The NTRK1 gene plays an important role in sensory and sympathetic neuronal survival. Mutations in this gene cause a rare hereditary disease known as congenital insensitivity to pain with anhidrosis. The aim of this study was to explore possible associations between single-nucleotide polymorphisms (SNPs) in NTRK1 and pain perception in a selected population. METHODS: A total of 309 healthy Han Chinese female undergraduates were recruited. Responses to quantitative sensory testing of pressure pain (dull, sharp, and acupuncture) were assessed, and genotyping of 13 tag-SNPs of NTRK1 was performed in the undergraduates recruited...
October 17, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/29054189/development-of-a-diagnosis-model-for-coronary-artery-disease
#2
Hongzeng Xu, Zhiying Duan, Chi Miao, Song Geng, Yuanzhe Jin
BACKGROUND: The purpose of this study was to develop a coronary artery disease (CAD) prediction model that optimally estimates the pre-test probability of CAD for patients suspected of CAD. METHODS AND RESULTS: This retrospective, multi-centre study included 7360 consecutive patients (4678 men, 57.87±11.42 years old; 2682 women, 61.60±9.58 years old) who underwent coronary angiography for evaluation of CAD. A prediction model was fitted for diagnosis of CAD with the help of eight significant risk factors including sex, age, smoking status, diabetes, hypertension, dyslipidaemia, serum creatinine and angina...
September 2017: Indian Heart Journal
https://www.readbyqxmd.com/read/29053974/depression-as-seen-through-the-eyes-of-rural-chinese-women-implications-for-help-seeking-and-the-future-of-mental-health-care-in-china
#3
Peiyuan Qiu, Eric D Caine, Fengsu Hou, Catherine Cerulli, Marsha N Wittink
BACKGROUND: As part of a larger epidemiological study of depression among rural Chinese women, we sought to understand their explanatory models of depression. We explored how participants describe depression, to what cause they attribute depression, and what sources of treatment they would recommend. METHODS: Participants first were assessed with the Center for Epidemiological-Depression scale (CES-D), with a cut-point of 16 or greater indicative of depression. The Short Explanatory Model Interview (SEMI), a semi-structured questionnaire, was our primary tool for exploring participants' explanatory models relating to a vignette describing a rural Chinese woman with depression...
October 6, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29053519/a-low-cost-simulator-for-training-in-endoscopic-assisted-transaxillary-dual-plane-breast-augmentation
#4
Chenglong Wang, Lin Chen, Dali Mu, Minqiang Xin, Jie Luan
BACKGROUND: Endoscopic-assisted transaxillary dual-plane (EATD) technique is a popular procedure for breast augmentation, especially for Chinese women. However, frustration is often expressed by plastic surgeons when first attempting EATD surgery. Simulation-based teaching is beneficial for EATD training, but it is expensive. This study presents a low-cost simulator to help plastic surgeons exercise psychomotor skills during EATD surgery. METHODS: The low-cost simulator was invented by Dr Jie Luan (the senior author) and made of some easily available materials including a mannequin, a T-shirt printed the bottom anatomical structure of the chest, the order of dissection, and the potential bleeding spot, and an elastic compression garment printed the upper anatomical structure and the cut-off position to sever the pectoralis major muscle...
October 19, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29049932/determinants-of-comorbid-depression-and-anxiety-postnatally-a-longitudinal-cohort-study-of-chinese-canadian-women
#5
Cindy-Lee Dennis, Hilary K Brown, Susitha Wanigaratne, Simone N Vigod, Sophie Grigoriadis, Kenneth Fung, Flavia Marini, Sarah Brennenstuhl
BACKGROUND: Women with comorbid depression and anxiety in the postpartum period experience more complex and severe symptoms than women with depression or anxiety alone; however, little is known about what influences these symptoms, especially among women from specific ethnic backgrounds. The objective of this study was to identify determinants of comorbid depression and anxiety symptomatology by 24 weeks postpartum in a cohort of Chinese-Canadian women. METHODS: A longitudinal cohort study was completed where 549 Chinese immigrant and Canadian-born women in Toronto were followed to 24 weeks postpartum...
September 25, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29049094/validation-of-the-avita-bpm64-upper-arm-blood-pressure-monitor-for-home-blood-pressure-monitoring-according-to-the-european-society-of-hypertension-international-protocol-revision-2010
#6
Yuan-Yuan Kang, Qi Chen, Chang-Yuan Liu, Yan Li, Ji-Guang Wang
OBJECTIVE: The aim of this study was to evaluate the accuracy of the automated oscillometric upper arm blood pressure (BP) monitor AVITA BPM64 for home BP monitoring according to the International Protocol of the European Society of Hypertension revision 2010. METHODS: Systolic and diastolic BPs were measured sequentially in 33 adult Chinese (14 women, mean age 47.0 years) using a mercury sphygmomanometer (two observers) and the AVITA BPM64 device (one supervisor)...
October 18, 2017: Blood Pressure Monitoring
https://www.readbyqxmd.com/read/29048227/nephrolithiasis-among-middle-aged-and-elderly-urban-chinese-a-report-from-prospective-cohort-studies-in-shanghai
#7
Xiang Shu, Hui Cai, Yong-Bing Xiang, Honglan Li, Loren Lipworth, Nicole L Miller, Wei Zheng, Xiao-Ou Shu, Ryan S Hsi
INTRODUCTION: Kidney stone risk factors are understudied among Asians. Our study objective was to investigate associations of obesity and other chronic diseases with incident kidney stones among the urban Chinese. PATIENTS AND METHODS: Included in this study are 2 prospective cohorts: the Shanghai Women's Health Study (N = 69,166) and Shanghai Men's Health Study (N= 58,054). Incident kidney stones were determined by self-report in 2004 and 2008. Cox regression models were used to evaluate the associations of study variables with stone risk with adjustment of demographics, medical history, and dietary intakes...
October 19, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/29047186/il-1rn-gene-polymorphisms-were-associated-with-breast-cancer-risk-in-a-chinese-han-population
#8
Tianbo Jin, Wei Cao, Xiaoxiao Zuo, Miao Li, Ya Yang, Tiansong Liang, Hongyao Yang, Xinhan Zhao, Daoke Yang
BACKGROUND: Interleukin (IL) is a large family of endogenous cytokine which are crucial in the regulation of inflammation and immunological responses. IL-1 receptor antagonist (IL-1RN) has been found to be associated with risk breast cancer (BC) in Korean and Indian women. However, little information is found about the polymorphisms of IL-1RN in Chinese Han BC patient. METHODS: We investigated the association between single-nucleotide polymorphisms (SNPs) in IL-1RN and BC risk in a case-control study that included 530 BC cases and 628 healthy controls...
October 18, 2017: Journal of Gene Medicine
https://www.readbyqxmd.com/read/29045673/age-related-changes-in-the-mitochondria-of-human-mural-granulosa-cells
#9
Yifan Liu, Ming Han, Xiaoshuang Li, Hui Wang, Minyue Ma, Shihui Zhang, Yifan Guo, Shuling Wang, Yuanfen Wang, N Duan, Bing Xu, Jingwen Yin, Yuanqing Yao
STUDY QUESTION: What changes in the mitochondria of human mural granulosa cells (mGCs) with maternal aging? SUMMARY ANSWER: The mitochondrial membrane potential (MMP) and the ability of oxidative phosphorylation (OXPHOS) of mGCs declines with reproductive aging, accompanied with more abnormal mitochondria. WHAT IS KNOWN ALREADY: Mitochondria play an important role in the dialogue between the mGCs and oocytes. However, the underlying mechanism of mitochondrial dysfunction in mGCs in aging is still poorly understood...
October 17, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29045343/brachial-ankle-pulse-wave-velocity-compared-with-mean-arterial-pressure-and-pulse-pressure-in-risk-stratification-in-a-chinese-population
#10
Yi-Chao Lu, Ping Lyu, Hong-Yan Zhu, Dong-Xu Xu, Sulaiman Tahir, Hai-Feng Zhang, Fang Zhou, Wen-Ming Yao, Lei Gong, Yan-Li Zhou, Rong Yang, Yan-Hui Sheng, Dong-Jie Xu, Xiang-Qing Kong, Jan A Staessen, Xin-Li Li
BACKGROUND: Brachial-ankle pulse wave velocity (baPWV) can be easily measured in an observer-independent way, but lacks robust population-based validation in terms of fatal combined with nonfatal outcomes. METHOD: To address this issue, we studied 4251 Chinese randomly recruited Gaoyou County (54.1% women; mean age, 52.1). RESULTS: In the whole study population, mean values were 102.4 mmHg for mean arterial pressure (MAP), 51.1 mmHg for pulse pressure, and 14...
October 16, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/29044766/do-men-and-women-with-intellectual-disabilities-understand-death
#11
A Y M Chow, J McEvoy, I K N Chan, M Borschel, J H L Yuen, J Y M Lo
BACKGROUND: Individuals with ID are often withheld information about the death of their loved ones as it has often been thought that they do not understand death or cannot grieve. This grief exacerbates the stress of individuals with ID as they often encounter secondary losses such as transitioning to a care facility. The aim of this study is to investigate men and women with ID understanding death concepts and to what extent. METHOD: Adopting a stratified random sampling method, 156 Chinese people with ID were invited to join the study...
October 18, 2017: Journal of Intellectual Disability Research: JIDR
https://www.readbyqxmd.com/read/29039556/huaier-extract-enhances-the-treatment-efficacy-of-paclitaxel-in-breast-cancer-cells-via-the-nf-%C3%AE%C2%BAb-i%C3%AE%C2%BAb%C3%AE-pathway
#12
Liu Yang, Zhenchuan Song, Xinle Wang, Wei Yang, Meiqi Wang, Huan Liu
Breast cancer is considered as the most common malignant disease in women. Huaier extract, a type of traditional Chinese medicine, has been found to have antitumor activity. In the present study, we aimed to investigate whether the combined treatments of paclitaxel and Huaier extract may improve treatment efficacy in breast cancer cells. Human breast cancer cell lines MCF-7 and MDA-MB-231 were used to evaluate the antitumor efficacy of Huaier extract and paclitaxel both in vitro and in vivo. Using proliferation assays and flow cytometry, we found that both Huaier extract and paclitaxel decreased cell viability and induced cell apoptosis in a time- and dose-dependent manner...
October 12, 2017: Oncology Reports
https://www.readbyqxmd.com/read/29038593/gender-and-lesion-number-dependent-difference-in-atherogenic-index-of-plasma-in-chinese-people-with-coronary-heart-disease
#13
Wei Ni, Zhenyu Zhou, Tao Liu, Haoyu Wang, Jianping Deng, Xiaoyan Liu, Guoqiang Xing
Few studies has investigated the interrelationship between Atherogenic index of plasma (AIP) and coronary heart disease (CHD) especially in Asians. AIP is the logarithmically transformed ratio of triglyceride (TG) to high-density lipoprotein cholesterol (HDL-C), and is thought to be associated with arteriosclerosis, hypertension, diabetes and cardiovascular diseases. Of the 463 patients from Central Hospital of Nanchong in 2011-2014 diagnosed with angiograms, 229 CHD (>50% stenosis in one or more arteries) and the rest 234 were the controls (maximum stenosis < 10% in any artery) according to the world health organization (who) diagnostic criteria...
October 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29037546/acceptance-towards-giving-birth-to-a-child-with-beta-thalassemia-major-a-prospective-study
#14
Yiu Man Chan, Oi Ka Chan, Yvonne Kwun Yue Cheng, Tak Yeung Leung, Terence Tzu Hsi Lao, Daljit Singh Sahota
OBJECTIVE: To explore the acceptance of pregnant Chinese women on giving birth to a child with beta-thalassemia major. MATERIALS AND METHODS: Women's acceptance on having a child with beta thalassemia major was assessed using standard gamble metrics during an interviewer-administered survey on 309 women recruited in the antenatal clinic. Utility scores were determined and the association with sociodemographic factors was assessed. RESULTS: The median utility score for having a child with beta-thalassemia major was 0...
October 2017: Taiwanese Journal of Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29036997/-mean-blood-pressure-among-the-adults-in-china-2010-2012-based-on-the-results-of-mercury-sphygmomanometer-and-converted-electronic-sphygmomanometer
#15
D M Yu, P Fu, W T Yu, H J Guo, X G Yang, W H Zhao, L Y Zhao
Objective: To analyze the average systolic blood pressure (SBP) and diastolic blood pressure (DBP) among adults aged 18 years old and above in China between 2010 and 2012; and to compare the difference in the results measured by mercury sphygmomanometer and converted electronic sphygmomanometer. Methods: The data was collected from Chinese Nutrition and Health Surveillance in 2010-2012. 120 428 adults aged 18 years old and above were selected from 150 survey counties (districts) of 31 provinces in China Mainland, by multi-stage stratified and probability proportion to size (PPS) cluster randomization sampling method...
October 6, 2017: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/29036869/the-relationship-between-trait-self-control-consideration-for-future-consequence-and-organizational-citizenship-behavior-among-chinese-employees
#16
Yu-Jie Wang, Kai Dou
BACKGROUND: Organizational citizenship behavior (OCB) is important to the development of an organization. Research into factors that foster OCB and the underlying processes are therefore substantially crucial. OBJECTIVE: The current study aimed to test the association between trait self-control and OCB and the mediating role of consideration for future consequence. METHOD: Four hundred and ninety-four Chinese employees (275 men, 219 women) took part in the study...
October 8, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/29036366/accounting-for-selectivity-bias-and-correlation-across-the-sequence-from-elevated-blood-pressure-to-hypertension-diagnosis-and-treatment
#17
Penny Gordon-Larsen, Samantha M Attard, Annie Green Howard, Barry M Popkin, Bing Zhang, Shufa Du, David K Guilkey
BACKGROUND: It is unknown whether efforts to reduce hypertension burden in countries with very high prevalence, would be more effective if directed at hypertension diagnosis vs. treatment. Most analyses do not address bias and correlation across the sequence from elevated blood pressure (BP) to hypertension diagnosis and treatment, leading to potentially misleading findings. METHODS: Using data spanning 18 years of the China Health and Nutrition Survey (n = 18,926; ages 18-75 years), we used an innovative 3-step, integrated system of equations to predict the sequence from: (i) elevated BP (systolic/diastolic BP ≥ 140/90 mm Hg) to (ii) diagnosed hypertension conditional on elevated BP, and to (iii) treatment (medication use) conditional on diagnosis, accounting for measured and unmeasured individual- and community-level confounders at each of the 3 steps...
September 26, 2017: American Journal of Hypertension
https://www.readbyqxmd.com/read/29035642/racial-and-ethnic-disparities-in-cancer-survival-the-contribution-of-tumor-sociodemographic-institutional-and-neighborhood-characteristics
#18
Libby Ellis, Alison J Canchola, David Spiegel, Uri Ladabaum, Robert Haile, Scarlett Lin Gomez
Purpose Racial/ethnic disparities in cancer survival in the United States are well documented, but the underlying causes are not well understood. We quantified the contribution of tumor, treatment, hospital, sociodemographic, and neighborhood factors to racial/ethnic survival disparities in California. Materials and Methods California Cancer Registry data were used to estimate population-based cancer-specific survival for patients diagnosed with breast, prostate, colorectal, or lung cancer between 2000 and 2013 for each racial/ethnic group (non-Hispanic black, Hispanic, Asian American and Pacific Islander, and separately each for Chinese, Japanese, and Filipino) compared with non-Hispanic whites...
October 16, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/29033240/single-nucleotide-polymorphisms-in-the-acylphosphatase-2-gene-and-the-snp-snp-interactions-on-the-risk-of-breast-cancer-in-chinese-han-women
#19
Junben Wu, Shujing Wang, Fanglan Liu, Shuluan Li
INTRODUCTION: The purpose of this study was to investigate the impact of single nucleotide polymorphisms (SNPs) in the acylphosphatase 2 gene and the SNP-SNP interactions on breast cancer (BC) risk in Chinese Han women. PATIENTS AND METHODS: A logistic regression model was used to examine the association between SNPs and BC risk. Odds ratios (ORs) and 95% confidence intervals (95% CIs) were calculated. Generalized multifactor dimensionality reduction was employed to analyze the SNP-SNP interaction...
September 19, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/29032578/first-trimester-screening-for-pre-eclampsia-in-chinese-pregnancies-case-control-study
#20
Yvonne Kwun Yue Cheng, Tak Yeung Leung, Lai Wa Law, Yuen Ha Ting, Kwok Ming Law, Daljit Singh Sahota
OBJECTIVE: To assess the potential of screening for pre-eclampsia (PE) in a Chinese population. DESIGN: Case Control Study. SETTING: Teaching Hospital in Hong Kong. POPULATION: 3,330 women having a viable singleton pregnancy attending 1(st) trimester Down syndrome screening. METHODS: Mean arterial pressure (MAP), bilateral uterine artery pulsatility index (UtA-PI), and placental growth factor (PlGF) were measured...
October 15, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
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