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https://www.readbyqxmd.com/read/29453821/trends-and-predictors-of-cesarean-birth-in-singapore-2005-2014-a-population-based-cohort-study
#1
Claudia Chi, Deanette Pang, Izzuddin M Aris, Wei Ting Teo, Sarah Weiling Li, Arijit Biswas, Eu Leong Yong, Yap Seng Chong, Kelvin Tan, Michael S Kramer
BACKGROUND: Rates of cesarean birth have continued to rise in many high-income countries. We examined the temporal trends and predictors of cesarean birth in Singapore. METHODS: Linked hospitalization and Birth Registry data were used to examine all live births to Singaporean citizens and permanent residents between January 1, 2005 and December 31, 2014 (n = 342 932 births). We calculated cesarean rates and age-adjusted average annual percent change (AAPC) in those rates and used sequential multivariable regression modeling to assess the contribution of changes in predictors to the change in cesarean rates over time...
February 17, 2018: Birth
https://www.readbyqxmd.com/read/29453810/a-case-control-study-and-meta-analysis-reveal-the-association-between-cox-2-g-765c-polymorphism-and-primary-end-stage-hip-and-knee-osteoarthritis
#2
Wei Huang, Chen Deng, Feng Tian, Weilu Gao, Zhenfei Ding, Xianliang Rao, Zongsheng Yin
BACKGROUND: Osteoarthritis (OA) is a popular arthrosis featured as pain, limited joint activity, and deformity. Cyclooxygenase-2 (COX-2) has been reported to be up-regulated in arthritic tissues and is integral to the progression of osteoarthritis (OA). Previous studies showed the COX-2 promoter G-765C polymorphism could influence COX-2 expression. However, the relationship between the variant and OA risk is contrasting. METHODS: We conducted a case-control study with 196 primary end-stage hip and knee OA cases and 196 controls in a Chinese Han population...
February 17, 2018: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/29451995/sex-dependent-choroidal-thickness-differences-in-healthy-adults-a-study-based-on-original-and-synthesized-data
#3
Wei Wang, Miao He, Xingwu Zhong
PURPOSE: The purpose of this study is to determine the influence of sex on choroidal thickness (CT) in healthy adults. METHODS: Healthy Chinese adults were recruited and complete ophthalmic examinations were performed. The choroid was imaged by swept-source optical coherence tomography and the macular CT in Early Treatment Diabetic Retinopathy Study grids was obtained by the intrinsic automated segmentation software. CT in males and females was compared after controlling other factors...
February 16, 2018: Current Eye Research
https://www.readbyqxmd.com/read/29449665/prediction-of-vaginal-birth-after-cesarean-delivery-in-chinese-parturients
#4
Juan Wen, Xuejing Song, Hongjuan Ding, Xiaofeng Shen, Rong Shen, Ling-Qun Hu, Wei Long
There is an urgent need in China to better predict vaginal birth after cesarean (VBAC) to face the challenge of the second child policy. We aimed to validate a widely used VBAC prediction model (Grobman's model) and a modified version of this model in a Chinese population. In this retrospective cohort study, 444 women with one cesarean delivery and at least one subsequent attempt for a trial of labor in Nanjing, China were included. The considered potential VBAC predictors included Grobman's background variables and five new variables...
February 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29447382/randomized-controlled-trial-of-acupuncture-for-women-with-fibromyalgia-group-acupuncture-with-traditional-chinese-medicine-diagnosis-based-point-selection
#5
Scott D Mist, Kim Dupree Jones
Background: Group acupuncture is a growing and cost-effective method for delivering acupuncture in the United States and is the practice model in China. However, group acupuncture has not been tested in a research setting. Objective: To test the treatment effect of group acupuncture vs group education in persons with fibromyalgia. Design: Random allocation two-group study with repeated measures. Setting: Group clinic in an academic health center in Portland, Oregon...
February 13, 2018: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29447359/actn3-genotype-and-physical-function-and-frailty-in-an-elderly-chinese-population-the-rugao-longevity-and-ageing-study
#6
Teng Ma, Deyi Lu, Yin-Sheng Zhu, Xue-Feng Chu, Yong Wang, Guo-Ping Shi, Zheng-Dong Wang, Li Yu, Xiao-Yan Jiang, Xiao-Feng Wang
Objective: To examine the associations of the actinin alpha 3 gene (ACTN3) R577X polymorphism with physical performance and frailty in an older Chinese population. Methods: Data from 1,463 individuals (57.8% female) aged 70-87 years from the Rugao Longevity and Ageing Study were used. The associations between R577X and timed 5-m walk, grip strength, timed Up and Go test, and frailty index (FI) based on deficits of 23 laboratory tests (FI-Lab) were examined. Analysis of variance and linear regression models were used to evaluate the genetic effects of ACTN3 R577X on physical performance and FI-Lab...
February 13, 2018: Age and Ageing
https://www.readbyqxmd.com/read/29447347/cultural-adaptation-of-an-evidence-based-lifestyle-intervention-for-diabetes-prevention-in-chinese-women-at-risk-for-diabetes-results-of-a-randomized-trial
#7
Zenong Yin, Judith Perry, Xiaoqin Duan, Meizi He, Ryan Johnson, Yanling Feng, Mark Strand
Background: The prevalence of both obesity and type 2 diabetes has been on the rise in China. This randomized controlled trial was conducted to test the feasibility and effectiveness of an evidence-based diabetes prevention program in Yuci, Shanxi Province, China from 2012 to 2014. Methods: Women with pre-diabetes, ages 25-65 y, were assigned randomly to a comparison (n=75) or 6-mo lifestyle intervention condition (n=109). Weight, fasting glucose, hemoglobin A1c and self-reported diet and physical activity were measured at baseline, 6 mo and 12 mo...
February 13, 2018: International Health
https://www.readbyqxmd.com/read/29445909/the-relationship-among-preconception-depression-anxiety-and-social-support-of-the-reproductive-aged-women-in-china
#8
Jihong Xu, Ping Chen, Xu Ma
The reproductive-aged women have to face physiological and psychological challenges as long as they plan to conceive. However, most previous studies focused on depression and anxiety during pregnancy. This study aimed to investigate the association among preconception depression, anxiety, and social support of the Chinese reproductive-aged women. Nine-hundred five reproductive-aged women who planned to conceive for the first or second time in the next three months were recruited through the Maternity and Child Healthcare Hospital and Obstetrics and Gynecology Hospital from three provinces in China...
February 14, 2018: Archives of Women's Mental Health
https://www.readbyqxmd.com/read/29445357/gender-difference-in-the-association-of-early-vs-late-onset-type-2-diabetes-with-non-fatal-microvascular-disease-in-china-a-cross-sectional-study
#9
Xiaoxu Huo, Junqing Zhang, Xiaohui Guo, Juming Lu, Jing Li, Wei Zhao, Linong Ji, Xilin Yang
Background: This study aimed to test whether early-onset (defined as <40 years of age) type 2 diabetes mellitus (T2DM) imparted different risks of microvascular disease to Chinese men and women. Methods: 222,537 Chinese patients with T2DM were recruited in 630 hospitals from 106 cities in 30 provinces of China in 2012 using a cross-sectional design. Logistic regression analysis was performed to obtain odds ratios (ORs) of male vs. female for diabetic retinopathy (DR) and diabetic nephropathy (DN)...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29444785/longitudinal-changes-in-intraocular-pressure-and-association-with-systemic-factors-and-refractive-error-lingtou-eye-cohort-study
#10
Xiaotong Han, Tangjian Yang, Jian Zhang, Sha Yu, Xinxing Guo, William Yan, Yin Hu, Mingguang He
OBJECTIVES: To investigate the longitudinal changes in intraocular pressure (IOP) and its associations with refractive error and systemic determinants in a Chinese geriatric population. DESIGN: Prospective cohort study. SETTING: Guangzhou Government Servant Physical Check-up Center, Guangzhou, China. PARTICIPANTS: 4413 government employees aged no less than 40 years (41.9% female) attending annual physical and eye examinations were included in this study...
February 14, 2018: BMJ Open
https://www.readbyqxmd.com/read/29444570/pyrethroid-pesticide-exposure-and-risk-of-primary-ovarian-insufficiency-in-chinese-women
#11
Chunming Li, Miaofeng Cao, Linjuan Ma, Xiaoqing Ye, Yang Song, Wuye Pan, Zhengfen Xu, Xiaochen Ma, Yibing Lan, Peiqiong Chen, Weiping Liu, Jing Liu, Jianhong Zhou
Pyrethroids are a class of widely used insecticides. Female animal studies suggested that pyrethroid exposure impaired ovarian function, which resulted in similar symptoms of primary ovarian insufficiency (POI). However, it is still unknown whether this association applies to women. In this case-control study, a total of 172 POI patients and 247 control women were recruited in Zhejiang, China. The urinary concentrations of metabolites of pyrethroids, 3-phenoxybenzoic acid (3-PBA) and 4-fluoro-3-phenoxybenzoic acid (4-F-3-PBA), as well as the serum concentrations of follicle-stimulating hormone (FSH), luteinizing hormone (LH) and anti-Mullerian hormone (AMH) were determined...
February 15, 2018: Environmental Science & Technology
https://www.readbyqxmd.com/read/29444361/environmental-exposure-to-polycyclic-aromatic-hydrocarbons-kitchen-ventilation-fractional-exhaled-nitric-oxide-and-risk-of-diabetes-among-chinese-females
#12
Jian Hou, Huizhen Sun, Yun Zhou, Youjian Zhang, Wenjun Yin, Tian Xu, Juan Cheng, Weihong Chen, Jing Yuan
Diabetes is related to exposure to polycyclic aromatic hydrocarbons (PAHs), inflammation in the body and housing characters. However, associations of urinary monohydroxy-PAHs (OH-PAHs) or fractional exhaled nitric oxide (FeNO) with diabetes risk in relation to housing characters are unclear. In this study, 2645 individuals were drawn from the baseline survey of the Wuhan-Zhuhai Cohort Study. Associations of diabetes with urinary OH-PAHs or FeNO among cooking participants were estimated using logistics regression models...
February 14, 2018: Indoor Air
https://www.readbyqxmd.com/read/29443463/odanacatib-pharmacokinetics-comparison-between-chinese-and-non-chinese-postmenopausal-women
#13
Xia Chen, Ji Jiang, Pei Hu, Stefan Zajic, Wen Liu, Jacqueline McCrea, Fang Liu, Rose Witter, Eric Mangin, S Aubrey Stoch
Odanacatib (ODN), an oral selective inhibitor of cathepsin K, was an investigational agent previously in development for the treatment of osteoporosis. In this phase 1 open-label study, 12 healthy Chinese postmenopausal women received single-dose ODN 50 mg on day 1 and multiple-dose ODN 50 mg once weekly on days 15, 22, 29, and 36 under fasted conditions. Pharmacokinetic (PK) parameters were evaluated on days 1 and 36. Multiple-dose area under the concentration-time profile (AUC0-168h) and maximum plasma concentration (Cmax) were compared with historical data from 9 non-Chinese postmenopausal women who also received ODN 50 mg once weekly for 4 weeks...
February 14, 2018: Clinical Pharmacology in Drug Development
https://www.readbyqxmd.com/read/29442412/effect-of-chewing-gum-on-gastrointestinal-function-after-gynecological-surgery-a-systematic-literature-review-and-meta-analysis
#14
Chao Xu, Jie Peng, Su Liu, Dun-Yi Qi
AIM: Recently, several randomized controlled trials (RCT) reported the effect of chewing gum on gastrointestinal function after gynecological surgery; however, these results are inconsistent. The aim of this study was to systematically analyze the effect of chewing gum on postoperative gastrointestinal function and complications in women undergoing gynecological surgery. METHODS: Pumbed, Embase, Cochrane Library, Web of Science, Chinese Wanfang databases, China National Knowledge Infrastructure and http://clinicaltrials...
February 14, 2018: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29441696/relationships-between-family-resilience-and-posttraumatic-growth-in-breast-cancer-survivors-and-caregiver-burden
#15
Ye Liu, Yuli Li, Lijun Chen, Yurong Li, Weiye Qi, Li Yu
OBJECTIVE: To examine the relationships between family resilience and posttraumatic growth (PTG) of breast cancer survivors and caregiver burden among principal caregivers in China. METHODS: Participants in this cross-sectional study comprised 108 women aged 26-74 years (M = 49, SD = 9) with early-stage breast cancer and 108 principal caregivers. Participants were recruited from a comprehensive cancer center of a public hospital in Shandong Province, China. The principal caregivers completed the Shortened Chinese Version of the Family Resilience Assessment Scale (FRAS-C) and the Chinese Version of the Zarit Caregiver Burden Interview (CZBI); patients completed the Short Form of the Posttraumatic Growth Inventory (PTGI-SF) and questions designed to obtain sociodemographic information...
February 13, 2018: Psycho-oncology
https://www.readbyqxmd.com/read/29440184/household-air-pollution-and-measures-of-blood-pressure-arterial-stiffness-and-central-haemodynamics
#16
Jill Baumgartner, Ellison Carter, James J Schauer, Majid Ezzati, Stella S Daskalopoulou, Marie-France Valois, Ming Shan, Xudong Yang
OBJECTIVE: We evaluated the exposure-response associations between personal exposure to air pollution from biomass stoves and multiple vascular and haemodynamic parameters in rural Chinese women. METHODS: We analysed the baseline information from a longitudinal study in southwestern China. Women's brachial and central blood pressure and pulse pressure, carotid-femoral pulse wave velocity and augmentation index, and their 48-hour personal exposures to fine particulate matter (PM 2...
February 9, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29439691/what-matters-most-protocol-for-a-randomized-controlled-trial-of-breast-cancer-surgery-encounter-decision-aids-across-socioeconomic-strata
#17
Marie-Anne Durand, Renata West Yen, A James O'Malley, Mary C Politi, Shubhada Dhage, Kari Rosenkranz, Katie Weichman, Julie Margenthaler, Anna N A Tosteson, Eloise Crayton, Sherrill Jackson, Ann Bradley, Robert J Volk, Karen Sepucha, Elissa Ozanne, Sanja Percac-Lima, Julia Song, Jocelyn Acosta, Nageen Mir, Glyn Elwyn
BACKGROUND: Breast cancer is the most commonly diagnosed malignancy in women. Mastectomy and breast-conserving surgery (BCS) have equivalent survival for early stage breast cancer. However, each surgery has different benefits and harms that women may value differently. Women of lower socioeconomic status (SES) diagnosed with early stage breast cancer are more likely to experience poorer doctor-patient communication, lower satisfaction with surgery and decision-making, and higher decision regret compared to women of higher SES...
February 13, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29439081/long-term-trends-of-liver-cancer-mortality-by-gender-in-urban-and-rural-areas-in-china-an-age-period-cohort-analysis
#18
Yuanyuan Sun, Yanhong Wang, Mengmeng Li, Kailiang Cheng, Xinyu Zhao, Yuan Zheng, Yan Liu, Shaoyuan Lei, Li Wang
OBJECTIVES: To provide an up-to-date overview of long-term trends of liver cancer mortality and evaluate the effects attributable to age, period and cohort in Chinese population stratified by gender and urban/rural areas. METHODS: Population and liver cancer mortality data were obtained based on the Disease Surveillance Points in China from 1991 to 2014. To examine the time trends of liver cancer mortality by gender in urban and rural areas in China, Joinpoint analysis was used to estimate the annual per cent change...
February 8, 2018: BMJ Open
https://www.readbyqxmd.com/read/29438509/dose-distribution-in-a-breast-undergoing-mammography-based-on-a-3d-detailed-breast-model-for-chinese-women
#19
Wenjing Wang, Rui Qiu, Li Ren, Zechen Feng, Zhen Wu, Chunyan Li, Yantao Niu, Junli Li
Not only the mean glandular dose (MGD) but also the glandular dose distribution is important in describing the radiation exposure to breast in mammography. For a more precise knowledge of the absorbed dose distribution in the breast, experimental measurements with thermoluminescence dosemeter and Monte Carlo simulations with Geant4 were performed in this study. The experimental measurements with homogeneous physical breast phantoms were used to validate Monte Carlo simulations of homogeneous mathematical breast models undergoing mammography...
February 9, 2018: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/29435039/characterization-of-mutations-in-brca1-2-and-the-relationship-with-clinic-pathological-features-of-breast-cancer-in-a-hereditarily-high-risk-sample-of-chinese-population
#20
Min Fang, Li Zhu, Hengyu Li, Xizhou Li, Yanmei Wu, Kainan Wu, Jian Lin, Yuan Sheng, Yue Yu
The database of BRCA1/2 mutations in Chinese population remains incomplete at present. Therefore, the present study aimed to report specific harmful BRCA1/2 mutations in the Chinese population and discuss the clinicopathological features in mutation carriers. BRCA1/2 germline mutation tests for 71 patients with breast cancer from a hereditarily high-risk Chinese population were performed using next-generation sequencing for identification of deleterious mutations. Furthermore, the clinicopathological features between BRCA1/2 mutation carriers and non-carriers were compared...
March 2018: Oncology Letters
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