keyword
MENU ▼
Read by QxMD icon Read
search

midline

keyword
https://www.readbyqxmd.com/read/28098558/platelet-derived-growth-factor-pdgf-signaling-directs-cardiomyocyte-movement-toward-the-midline-during-heart-tube-assembly
#1
Joshua Bloomekatz, Reena Singh, Owen Wj Prall, Ariel C Dunn, Megan Vaughan, Chin-San Loo, Richard P Harvey, Deborah Yelon
Communication between neighboring tissues plays a central role in guiding organ morphogenesis. During heart tube assembly, interactions with the adjacent endoderm control the medial movement of cardiomyocytes, a process referred to as cardiac fusion. However, the molecular underpinnings of this endodermal-myocardial relationship remain unclear. Here, we show an essential role for platelet-derived growth factor receptor alpha (Pdgfra) in directing cardiac fusion. Mutation of pdgfra disrupts heart tube assembly in both zebrafish and mouse...
January 18, 2017: ELife
https://www.readbyqxmd.com/read/28098413/dermatomal-spread-following-posterior-transversus-abdominis-plane-block-in-pediatric-patients-our-initial-experience
#2
Maria A Hernandez, Tricia Vecchione, Karen Boretsky
INTRODUCTION: Several techniques for the transversus abdominis plane (TAP) block have been described. The extent of sensory changes using an ultrasound-guided posterior TAP block (pTAP) remains unclear in pediatric patients. The primary aim of this study was to report the extent of sensory changes achieved with pTAP; specifically the highest thoracic dermatome anesthetized. Secondary outcomes were pain scores (PS), opioid consumption, and complications. METHODS: We retrospectively reviewed the medical records of patients less than 21 years of age undergoing abdominal surgery with a unilateral or bilateral pTAP(s) for postoperative analgesia...
January 18, 2017: Paediatric Anaesthesia
https://www.readbyqxmd.com/read/28095928/one-hundred-years-of-external-approach-medialisation-thyroplasty
#3
V E Crolley, N Gibbins
It has been 100 years since Erwin Payr first developed an operation to improve the effects of a paralysed vocal fold, and operations based on this technique are still in use today. This technique, medialisation thyroplasty, aims to improve the symptoms caused by vocal fold palsy by realigning the lateralised vocal fold into the midline. Whilst the effects of vocal fold palsy were recognised in antiquity, it was only with the development of indirect laryngoscopy in the late nineteenth century that the vocal fold paralysis could be identified as an aetiology for poor phonation and dysphagia...
January 18, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28092970/surgery-of-anterior-skull-base-lesions-in-children
#4
Thomas Karl Hoffmann, Marc Oliver Scheithauer, Fabian Sommer, Jörg Lindemann, Ernst-Johannes Haberl, Ulrike Friebe-Hoffmann, Marie-Nicole Theodoraki
INTRODUCTION: Lesions affecting the anterior skull base represent a rare group of craniofacial pathologies. A tumor of the facial midline, meningitis, or rhinoliquorrhea may be indicative of malformations like dermoid cysts, gliomas, encephaloceles, or nasal fistulas. METHODS: We present a case series of 13 children (4 months to 12 years; 8 males, 5 females) with lesions involving the anterior skull base, which were treated surgically in an interdisciplinary setting...
January 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28092335/distribution-pattern-of-the-superior-and-the-inferior-labial-arteries-impact-for-safe-upper-and-lower-lip-augmentation-procedures
#5
Cotofana Sebastian, Pretterklieber Bettina, Lucius Runhild, Frank Konstantin, Haas Maximilian, Schenck L Thilo, Gleiser Corinna, Weyers Imke, Wedel Thilo, Pretterklieber Michael
BACKGROUND: Understanding the precise position and course of the superior and inferior labial arteries within the upper and the lower lip is crucial for safe and complication free applications of volumizing materials. METHODS: 193 anatomic head specimens (56.5% females) of Caucasian ethnicity were investigated in this large multi-centric anatomical study. In total six 3cm long vertical incisions were performed on each lip (midline and 1cm medial to the angles of the mouth) to identify the position of the superior and the inferior labial arteries in relation to the orbicularis oris muscle...
January 12, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28092095/noradrenergic-transmission-in-the-central-medial-thalamic-nucleus-modulates-the-electroencephalographic-activity-and-emergence-from-propofol-anesthesia-in-rats
#6
Bao Fu, Tian Yu, Jie Yuan, Xingrui Gong, Mazhong Zhang
At present, the mechanisms by which general anesthetics causing loss of consciousness remain unclear. The central medial thalamic nucleus (CMT) is a rarely studied component of the midline thalamic complex, which is deemed to be a part of the nonspecific arousal system. Despite the fact that CMT participates in modulating arousal and receives excitatory noradrenergic projections from locus coeruleus (LC), it remains unknown whether the noradrenergic pathway in the CMT takes part in modulating the arousal system...
January 16, 2017: Journal of Neurochemistry
https://www.readbyqxmd.com/read/28091734/level-of-conus-medullaris-termination-in-adult-population-analyzed-by-kinetic-magnetic-resonance-imaging
#7
An Liu, Kaixiang Yang, Daling Wang, Changqing Li, Zhiwei Ren, Shigui Yan, Zorica Buser, Jeffrey C Wang
PURPOSE: To investigate the change of conus medullaris termination (CMT) level in neutral, flexion and extension positions and to analyze the effects of age and gender on the CMT level. METHODS: The midline sagittal T2-weighted kinetic magnetic resonance imaging (kMRI) study of 585 patients was retrospectively reviewed to identify the level of CMT. All patients were in an upright position. A straight line perpendicular to the long axis of the cord was drawn from the tip of the cord and then subtended to the adjacent vertebra or disk space...
January 16, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28090629/what-is-the-l-in-lpds-localized-as-well-as-lateralized
#8
E Hartl, J Rémi, C Stoyke, S Noachtar
BACKGROUND: Periodic discharges (PDs) are well established as either periodic lateralized epileptiform discharges (LPDs) or generalized discharges. However, PDs in the midline can currently not be adequately classified as they are not generalized and not lateralized. AIMS OF THE STUDY: To propose a modification of the current LPD classification. METHODS: We here present a paradigmatic case series of three adult patients with midline LPDs. RESULTS: In our patients, ictal electroencephalography (EEG) recordings revealed periodic epileptiform discharges in the midline region...
January 16, 2017: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/28089837/direct-midline-posterior-corpectomy-and-fusion-of-a-lumbar-burst-fracture-with-retrospondyloptosis-a-case-report
#9
Arthur Carminucci, Rachid Assina, R Nick Hernandez, Ira M Goldstein
BACKGROUND: Traumatic burst fractures of the lumbar spine can result in significant neurological injury and mechanical instability. The ideal surgical approach for the treatment of unstable lumbar spine burst fractures remains debatable. CASE DESCRIPTION: A 37 year-old male presented with severe neurological injury including loss of motor function below the level of the iliopsoas muscles bilaterally, saddle anesthesia, and absent rectal tone, following a fall from 60 ft...
January 9, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28089528/hydrogel-spacer-distribution-within-the-perirectal-space-in-patients-undergoing-radiotherapy-for-prostate-cancer-impact-of-spacer-symmetry-on-rectal-dose-reduction-and-the-clinical-consequences-of-hydrogel-infiltration-into-the-rectal-wall
#10
Benjamin W Fischer-Valuck, Anupama Chundury, Hiram Gay, Walter Bosch, Jeff Michalski
PURPOSE: Hydrogel prostate-rectum spacers, biomaterials placed between the prostate and rectum, continue to gain interest as a method to reduce or limit rectal dose during dose escalated prostate cancer radiation therapy. Because the spacer is initially injected into the perirectal space as a liquid, the final distribution can vary. The purpose of this study was to evaluate hydrogel spacer (SpaceOAR system) implantation and distribution from a recent prospective randomized control trial and correlate spacer symmetry with rectal dose reduction as well as rectal wall infiltration (RWI) to acute and late toxicity...
October 17, 2016: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28089518/transcriptional-pre-patterning-of-drosophila-gastrulation
#11
Bomyi Lim, Michael Levine, Yuji Yamakazi
Gastrulation of the Drosophila embryo is one of the most intensively studied morphogenetic processes in animal development [1-4]. Particular efforts have focused on the formation of the ventral furrow, whereby ∼1,000 presumptive mesoderm cells exhibit coordinated apical constrictions that mediate invagination [5, 6]. Apical constriction depends on a Rho GTPase signaling pathway (T48/Fog) that is deployed by the developmental regulatory genes twist and snail [7-10]. It is thought that coordinate mesoderm constriction depends on high levels of myosin along the ventral midline, although the basis for this localization is uncertain...
January 9, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28088038/evidence-of-functional-duplicity-of-nestin-expression-in-the-adult-mouse-midbrain
#12
Parisa Farzanehfar, Shi Sheng Lu, Anupa Dey, Dharshani Musiienko, Hamzah Baagil, Malcolm K Horne, Tim D Aumann
Whether or not neurogenesis occurs in the adult substantia nigra pars compacta (SNc) is an important question relevant for developing better treatments for the motor symptoms of Parkinson's disease (PD). Although controversial, it is generally believed that dividing cells here remain undifferentiated or differentiate into glia, not neurons. However, there is a suggestion that Nestin-expressing neural precursor cells (NPCs) in the adult SNc have a propensity to differentiate into neurons, which we sought to confirm in the present study...
January 5, 2017: Stem Cell Research
https://www.readbyqxmd.com/read/28087916/-a-case-of-idiopathic-hypertrophic-cranial-pachymeningitis-presenting-as-chronic-subdural-hematoma
#13
Zhan He, Fang Ding, Jiandong Rong, Yongli Gan
A 26-year-old male presented with a 6-day history of paroxysmal headache which was worsen with nausea and vomiting for 1 day. Head CT on admission revealed left chronic subdural hematoma with midline shift. An emergency Burr hole drainage for hematoma was performed. Headache recurred 6 days later. MRI of the brain revealed a diffuse thickening and a gadolinium-enhancement of the falx, cranial dura mater and tentorium cerebelli on the left side with pia mater involved. Lumber puncture showed increased intracranial pressure and elevated IgG level in cerebrospinal fluid...
May 25, 2016: Zhejiang da Xue Xue Bao. Yi Xue Ban, Journal of Zhejiang University. Medical Sciences
https://www.readbyqxmd.com/read/28087632/sequential-organogenesis-sets-two-parallel-sensory-lines-in-medaka
#14
Ali Seleit, Isabel Krämer, Elizabeth Ambrosio, Nicolas Dross, Ulrike Engel, Lázaro Centanin
Animal organs are typically formed during embryogenesis by following one specific developmental programme. Here we report that neuromast organs are generated by two distinct and sequential programmes that result in parallel sensory lines in medaka embryos. A ventral posterior lateral line (pLL) is composed of neuromasts deposited by collectively migrating cells while a midline pLL is formed by individually migrating cells. Despite the variable number of neuromasts among embryos, the sequential programmes that we describe here fix an invariable ratio between ventral and midline neuromasts...
January 13, 2017: Development
https://www.readbyqxmd.com/read/28086878/a-case-of-cranium-bifidum-with-meningocele-in-ayrshire-calf
#15
Mosiany Letura Kisipan, Caleb Oburu Orenge, David Njogu Gacheru, Raphael Muchangi Ngure
BACKGROUND: Congenital cranial bone defects predispose to herniation of meninges, sometimes with brain tissue involvement, to form a cerebrospinal fluid (CSF)-filled cyst in the head. Such defects mainly results from focal failure of neural tube closure during fetal development and has been reported in various species of domestic mammals. CASE PRESENTATION: A one week old Ayrshire calf with a fluctuant swelling on parieto-occipital region of the head was referred to the faculty...
January 13, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28081125/the-neural-representation-of-prospective-choice-during-spatial-planning-and-decisions
#16
Raphael Kaplan, John King, Raphael Koster, William D Penny, Neil Burgess, Karl J Friston
We are remarkably adept at inferring the consequences of our actions, yet the neuronal mechanisms that allow us to plan a sequence of novel choices remain unclear. We used functional magnetic resonance imaging (fMRI) to investigate how the human brain plans the shortest path to a goal in novel mazes with one (shallow maze) or two (deep maze) choice points. We observed two distinct anterior prefrontal responses to demanding choices at the second choice point: one in rostrodorsal medial prefrontal cortex (rd-mPFC)/superior frontal gyrus (SFG) that was also sensitive to (deactivated by) demanding initial choices and another in lateral frontopolar cortex (lFPC), which was only engaged by demanding choices at the second choice point...
January 2017: PLoS Biology
https://www.readbyqxmd.com/read/28080963/is-the-cardiac-monitoring-function-related-to-the-self-in-both-the-default-network-and-right-anterior-insula
#17
Mariana Babo-Rebelo, Nicolai Wolpert, Claude Adam, Dominique Hasboun, Catherine Tallon-Baudry
The self has been proposed to be rooted in the neural monitoring of internal bodily signals and might thus involve interoceptive areas, notably the right anterior insula (rAI). However, studies on the self consistently showed the involvement of midline default network (DN) nodes, without referring to visceral monitoring. Here, we investigate this apparent discrepancy. We previously showed that neural responses to heartbeats in the DN encode two different self-dimensions, the agentive 'I' and the introspective 'Me', in a whole-brain analysis of magnetoencephalography (MEG) data...
November 19, 2016: Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences
https://www.readbyqxmd.com/read/28078737/3d-assessment-of-the-umbilical-vein-deviation-angle-uvda-for-the-prediction-of-liver-herniation-in-left-congenital-diaphragmatic-hernia
#18
Nicola Volpe, Eleonora Mazzone, Brunella Muto, Alice Suprani, Tiziana Fanelli, Christine Tita Kaihura, Andrea Dall'Asta, Giuseppe Pedrazzi, Carmine Del Rossi, Enrico Maria Silini, Cinzia Magnani, Paolo Volpe, Tullio Ghi, Tiziana Frusca
OBJECTIVES: To introduce a new sonographic marker of intrathoracic liver herniation in fetuses with left congenital diaphragmatic hernia (CDH) METHODS: In a consecutive series of fetuses with isolated CDH an ultrasound volume of the fetal abdomen was acquired. On this the offline calculation of the angle formed by the midline of the abdomen (joining the center of the vertebral body to the abdominal insertion of the umbilical cord) and a second line joining the center of the vertebral body to the intra-abdominal convexity of the umbilical vein was carried out (Umbilical Vein Deviation Angle or UVDA)...
January 12, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28077278/oscillatory-eeg-activity-induced-by-conditioning-stimuli-during-fear-conditioning-reflects-salience-and-valence-of-these-stimuli-more-than-expectancy
#19
J H Chien, L Colloca, A Korzeniewska, J J Cheng, C M Campbell, A E Hillis, F A Lenz
Imaging studies have described hemodynamic activity during fear conditioning protocols with stimulus trains in which a visual conditioned stimulus (CS+) is paired with an aversive unconditioned stimulus (US, painful laser pulse) while another visual stimulus is unpaired (CS-). We now test the hypothesis that CS Event Related Spectral Perturbations (ERSPs) are related to ratings of CS Expectancy (likelihood of pairing with the US), Valence (unpleasantness) and Salience (ability to capture attention). ERSP windows in EEG were defined by both time after the CS and frequency, and showed increased oscillatory power (Event Related Synchronization, ERS) in the delta/theta Windows (0-8 Hz) and the gamma Window (30-55 Hz)...
January 7, 2017: Neuroscience
https://www.readbyqxmd.com/read/28077165/malignant-transformation-of-a-long-standing-submental-dermoid-cyst-to-a-carcinosarcoma-a-case-report
#20
Nadeena Sri Swarnagupta Jayasuriya, Samadarani Siriwardena, Wanninayake Mudiyanselage Tilakaratne, Suchithra Parthiepan
BACKGROUND: Submental dermoid cysts are uncommon midline cysts which occur due to entrapment of ectoderm between the second and third branchial arches during embryogenesis. Most dermoid cysts of the head and neck are benign, but rarely malignant transformation may occur. To the best of our knowledge, this is the first report of a carcinosarcoma arising in a submental dermoid cyst. CASE PRESENTATION: A 42-year-old Sri Lankan Tamil man presented with a large cystic swelling in his submental region which was diagnosed as an extensive submental dermoid cyst...
January 11, 2017: Journal of Medical Case Reports
keyword
keyword
31781
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"