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https://www.readbyqxmd.com/read/29907446/salvaging-the-dehisced-glans-penis
#1
C M White, M K Hanna
OBJECTIVE: The glans penis may show a deep groove (surgically favorable), or may appear flat with an absent sulcus (unfavorable). Glans dehiscence following hypospadias repair, especially after multiple surgeries, frequently results in a scarred, obliterated, or absent urethral plate. The glans penis appears to be flat and grooveless. This study reported on the outcome of a two-stage salvage repair for glans dehiscence in 49 consecutive patients. MATERIALS AND METHODS: Retrospective chart review was performed for all patients who underwent repair for glans dehiscence following hypospadias repair...
May 30, 2018: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29746155/presurgical-nasal-molding-with-a-nasal-spring-in-patients-with-mild-to-moderate-nasal-deformity-with-incomplete-unilateral-cleft-lip-with-or-without-cleft-palate
#2
Supakit Peanchitlertkajorn
OBJECTIVE: Traditional nasoalveolar molding (NAM) requires steep learning curve for clinicians and significant compliance from parents. Nasal springs have been developed by the author to simplify presurgical nasal molding. This article presents the design, construction, and application of the spring. The treatment goal is to improve nasal deformity prior to primary repair in infants born with incomplete unilateral cleft lip with or without cleft palate. METHOD: The design, fabrication, and utility of the nasal spring are described...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29351039/resorbable-plates-in-secondary-cleft-nasal-reconstruction
#3
Pey-Yi Lin, Anthony P Gibson, John F Teichgraeber, Matthew R Greives
OBJECTIVE: The authors report on the use and complications of alloplastic resorbable plates and compare their use to autologous cartilage grafts in secondary cleft nasal reconstruction. DESIGN: Institutional review board (IRB)-approved retrospective chart review. SETTING: Texas Cleft-Craniofacial Center at the McGovern Medical School at the University of Texas Health Sciences Center at Houston. PATIENTS: Patients with unilateral or bilateral cleft lip nasal deformity who have undergone secondary correction of their nasal deformity with at least 1-year follow-up...
February 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29207917/functional-effects-of-snps-in-myh9-and-risks-of-nonsyndromic-orofacial-clefts
#4
Y Wang, D Li, Y Xu, L Ma, Y Lu, Z Wang, L Wang, W Zhang, Y Pan
Nonsyndromic orofacial clefts (NSOCs) are congenital newborn malformations. Myosin heavy chain 9 ( MYH9) is a candidate gene of NSOCs. To investigate the associations between single-nucleotide polymorphisms (SNPs) of MYH9 and NSOC susceptibility, a 2-stage case-control study was designed and 4 potentially functional SNPs of MYH9 (rs12107, rs2269529, rs9619601, rs5756130) were selected and genotyped by iPLEX Sequenom MassARRAY and TaqMan assay in the first stage (599 NSOC cases and 590 controls). The significant SNPs in the first stage were replicated in the second stage (676 NSOC cases and 705 controls) by TaqMan assay...
April 2018: Journal of Dental Research
https://www.readbyqxmd.com/read/29016629/three-dimensional-morphology-of-first-molars-in-relation-to-ethnicity-and-the-occurrence-of-cleft-lip-and-palate
#5
Sandra Echtermeyer, Philine H Metelmann, Alexander Hemprich, Karl-Heinz Dannhauer, Karl-Friedrich Krey
OBJECTIVES: This study aims to describe morphological peculiarities of maxillary and mandibular first molars in Europeans, Asians and Europeans with cleft lip and palate. MATERIAL AND METHODS: Reflex microscopy was used to obtain three-dimensional morphometric landmarks from 40 models (11 Europeans and 13 Asians without cleft lip and palate, 16 Europeans with unilateral cleft lip and palate). The cases were examined using traditional morphometry and geometric morphometry, and visualized using thin-plate splines...
2017: PloS One
https://www.readbyqxmd.com/read/28855714/the-pterygomaxillary-junction-an-imaging-study-for-surgical-information-of-lefort-i-osteotomy
#6
Yen-Po Chin, Maria Belen Leno, Sarayuth Dumrongwongsiri, Kyung Hoon Chung, Hsiu-Hsia Lin, Lun-Jou Lo
Maxillary osteotomy is a common surgical procedure and often involves separation of the pterygomaxillary junction (PMJ), which is a "blinded" procedure with inherent risks. Knowledge of the PMJ structure is essential. It remains unclear whether patients with different facial types have different PMJ structures, or different surgical outcome. This study evaluated the computed tomographic images of 283 consecutive patients who received orthognathic surgery. Patients were classified into Angle class I, II, III and cleft lip/palate groups...
August 30, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28459132/a-prospective-longitudinal-study-of-postnatal-dentoalveolar-and-palatal-growth-the-anatomical-basis-for-cad-cam-assisted-production-of-cleft-lip-palate-feeding-plates
#7
Franz X Bauer, Florian D Güll, Maximilian Roth, Lucas M Ritschl, Andrea Rau, Dominik Gau, Maximilian Gruber, Markus Eblenkamp, Bettina Hilmer, Klaus-Dietrich Wolff, Denys J Loeffelbein
This study describes the dentoalveolar and palatal growth during the first months of life. Knowledge concerning this development is essential to avoid unwanted events such as mucosal ulcerations or restriction of growth when cleft-lip and palate (CLP) patients are treated. The results involve the generation of CAD/CAM CLP-feeding plates. Intraoral impressions from 32 healthy newborns were taken monthly for 5 months, supplemented by measurements of body weight, length, and occipital-frontal head circumference...
October 2017: Clinical Anatomy
https://www.readbyqxmd.com/read/28174062/cephalometric-evaluation-after-two-stage-palatoplasty-combined-with-a-hotz-plate-a-comparative-study-between-the-modified-furlow-and-widmaier-perko-methods
#8
COMPARATIVE STUDY
K Madachi, R Takagi, T Asahito, Y Kodama, R Ominato, A Iida, K Ono, I Saito
The effects on craniofacial growth of two different soft palate repair techniques in two-stage palatoplasty were investigated. This was a retrospective, cross-sectional cohort study of 68 children with non-syndromic, complete unilateral cleft lip and palate. Thirty-four patients were treated with the modified Furlow method (F-group) and the remaining 34 with the Widmaier-Perko method (P-group). Craniofacial growth was assessed by analyzing 12 angular and 12 linear measurements on lateral cephalograms. Composite facial diagrams from the two groups were compared with those of a control non-cleft group...
May 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/27750176/computer-assisted-preoperative-simulation-for-positioning-and-fixation-of-plate-in-2-stage-procedure-combining-maxillary-advancement-by-distraction-technique-and-mandibular-setback-surgery
#9
Hideyuki Suenaga, Asako Taniguchi, Kazumichi Yonenaga, Kazuto Hoshi, Tsuyoshi Takato
INTRODUCTION: Computer-assisted preoperative simulation surgery is employed to plan and interact with the 3D images during the orthognathic procedure. It is useful for positioning and fixation of maxilla by a plate. We report a case of maxillary retrusion by a bilateral cleft lip and palate, in which a 2-stage orthognathic procedure (maxillary advancement by distraction technique and mandibular setback surgery) was performed following a computer-assisted preoperative simulation planning to achieve the positioning and fixation of the plate...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27550292/slow-versus-rapid-maxillary-expansion-in-bilateral-cleft-lip-and-palate-a-cbct-randomized-clinical-trial
#10
Araci Malagodi de Almeida, Terumi Okada Ozawa, Arthur César de Medeiros Alves, Guilherme Janson, José Roberto Pereira Lauris, Marilia Sayako Yatabe Ioshida, Daniela Gamba Garib
OBJECTIVES: The purpose of this "two-arm parallel" trial was to compare the orthopedic, dental, and alveolar bone plate changes of slow (SME) and rapid (RME) maxillary expansions in patients with complete bilateral cleft lip and palate (BCLP). MATERIAL AND METHODS: Forty-six patients with BCLP and maxillary arch constriction in the late mixed dentition were randomly and equally allocated into two groups. Computer-generated randomization was used. Allocation was concealed with sequentially, numbered, sealed, opaque envelopes...
June 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/27471470/microrna-profiling-during-craniofacial-development-potential-roles-for-mir23b-and-mir133b
#11
Hai-Lei Ding, Joan E Hooper, Peter Batzel, B Frank Eames, John H Postlethwait, Kristin B Artinger, David E Clouthier
Defects in mid-facial development, including cleft lip/palate, account for a large number of human birth defects annually. In many cases, aberrant gene expression results in either a reduction in the number of neural crest cells (NCCs) that reach the frontonasal region and form much of the facial skeleton or subsequent failure of NCC patterning and differentiation into bone and cartilage. While loss of gene expression is often associated with developmental defects, aberrant upregulation of expression can also be detrimental...
2016: Frontiers in Physiology
https://www.readbyqxmd.com/read/27460947/comparison-of-two-treatment-protocols-in-children-with-unilateral-complete-cleft-lip-and-palate-tridimensional-evaluation-of-the-maxillary-dental-arch
#12
COMPARATIVE STUDY
Paula Karine Jorge, Wanda Gnoinski, Karine Vaz Laskos, Cleide Felício Carvalho Carrara, Daniela Gamba Garib, Terumi Okada Ozawa, Maria Aparecida Andrade Moreira Machado, Fabrício Pinelli Valarelli, Thais Marchini Oliveira
OBJECTIVE: The aim of this study was to evaluate the dimensional alterations of the maxillary dental arches after lip repair in children with unilateral complete cleft lip and palate of two different protocols. MATERIAL AND METHODS: The sample was composed of 94 digital models and divided in two groups: Group I - 23 children, (protocol 1) - with presurgical orthopedic intervention: Hotz plate; Group II - 24 children, (protocol 2) - without presurgical orthopedic intervention...
September 2016: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/27400840/controversies-in-the-management-of-patients-with-cleft-lip-and-palate
#13
REVIEW
Regina E Rodman, Sherard Tatum
Cleft lip and palate is one of the most common congenital anomalies. For many years, surgeons have been attempting to reduce the severity of the deformity before the surgical repair to achieve a better outcome. The nasoalveolar molding technique uses acrylic nasal stents attached to the vestibular shield of an oral molding plate to mold the nasal alar cartilages into a more normal form and position during the presurgical period. Proponents of nasoalveolar molding claim several benefits, including improved aesthetic outcome, reduced overall costs, and a psychosocial benefit to the family...
August 2016: Facial Plastic Surgery Clinics of North America
https://www.readbyqxmd.com/read/27391495/maxillary-protraction-with-intermaxillary-elastics-to-miniplates-versus-bone-anchored-face-mask-therapy-in-cleft-lip-and-palate-patients
#14
Arezoo Jahanbin, Mozhgan Kazemian, Neda Eslami, Iman Saeedi Pouya
INTRODUCTION: Cleft lip and palate patients usually have deficient maxilla due to postsurgical scars. The aim this study was to compare the effectiveness of miniplates-anchored face-mask therapy versus intermaxillary elastics to miniplates for maxillary traction in cleft lip and palate patients. METHODS: This clinical trial included 11 prepubertal patients with cleft lip and palate. Initially, a w-arch expander was cemented and activated 3 mm per month to overcorrect the crossbite...
July 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27256742/-polycyclic-aromatic-hydrocarbons-exposure-and-birth-defects
#15
S S Lin, Y Huang, C Y Wang, A G Ren
Birth defects are one of the most common adverse birth outcomes, which create a heavy economic burden to the country, society and family. And they are also one of the biggest problems facing public health today. Polycyclic aromatic hydrocarbons (PAHs) are a group of toxic pollutants existing in the environment widely, resulting from incomplete organic matter combustion, and can be taken into the body through various ways including the digestive tract, respiratory tract and so on. Recent researches suggest that the exposure of PAHs may be associated with various birth defects, while the special mechanism isn't very clear...
June 2016: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/27243669/early-craniofacial-defects-in-zebrafish-that-have-reduced-function-of-a-wnt-interacting-extracellular-matrix-protein-tinagl1
#16
Hannah Neiswender, Sammy Navarre, David J Kozlowski, Ellen K LeMosy
OBJECTIVE:   Tinagl1 has a weak genetic association with craniosynostosis, but its functions in cartilage and bone development are unknown. Knockdown of Tinagl1 in zebrafish embryos allowed an initial characterization of its potential effects on craniofacial cartilage development and a test of whether these effects could involve Wnt signaling. RESULTS:   Tinagl1 knockdown resulted in dose-dependent reductions and defects in ventral pharyngeal arch cartilages as well as the ethmoid plate, a zebrafish correlate to the palate...
July 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/27227513/nasal-septal-anatomy-in-skeletally-mature-patients-with-cleft-lip-and-palate
#17
Jonathan P Massie, Christopher M Runyan, Marleigh J Stern, Michael Alperovich, Scott M Rickert, Pradip R Shetye, David A Staffenberg, Roberto L Flores
IMPORTANCE: Septal deviation commonly occurs in patients with cleft lip and palate (CLP); however, the contribution of the cartilaginous and bony septum to airway obstruction in skeletally mature patients is poorly understood. OBJECTIVES: To describe the internal nasal airway anatomy of skeletally mature patients with CLP and to determine the contributors to airway obstruction. DESIGN, SETTING, AND PARTICIPANTS: This single-center retrospective review included patients undergoing cone-beam computed tomography (CBCT) from November 1, 2011, to July 6, 2015, at the cleft lip and palate division of a major academic tertiary referral center...
September 1, 2016: JAMA Facial Plastic Surgery
https://www.readbyqxmd.com/read/27223625/computer-assisted-virtual-planning-for-surgical-guide-manufacturing-and-internal-distractor-adaptation-in-the-management-of-midface-hypoplasia-in-cleft-patients
#18
Paolo Scolozzi, Georges Herzog
We are reporting the treatment of severe maxillary hypoplasia in two patients with unilateral cleft lip and palate by using a specific approach combining the Le Fort I distraction osteogenesis technique coupled with computer-aided design/computer-aided manufacturing customized surgical guides and internal distractors based on virtual computational planning. This technology allows for the transfer of the virtual planned reconstruction to the operating room by using custom patient-specific implants, surgical splints, surgical cutting guides, and surgical guides to plate or distractor adaptation...
July 2017: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/27011740/prevalence-and-management-of-natal-neonatal-teeth-in-cleft-lip-and-palate-patients
#19
R Burcu Nur Yilmaz, Derya Germec Cakan, Nasim Mesgarzadeh
OBJECTIVE: The aim of this study was to determine the prevalence and distribution of natal/neonatal teeth in infants with cleft lip and palate (CLP) according to gender, involving jaw and side and to show the management of some cases. MATERIALS AND METHODS: A retrospective study was carried out on medical history and photographic records of 69 infants with CLP, who were treated at the CLP clinic of Yeditepe University between years 2014-2015. The presence of neonatal teeth was determined, and if present the gender, type of cleft, and position were recorded...
January 2016: European Journal of Dentistry
https://www.readbyqxmd.com/read/27002917/modified-activation-technique-for-nasal-stent-of-nasoalveolar-molding-appliance-for-columellar-lengthening-in-bilateral-cleft-lip-palate
#20
Pravinkumar G Patil, Smita P Nimbalkar-Patil
Bilateral cleft lip/cleft palate is associated with nasal deformities typified by a short columella. The presurgical nasoalveolar molding (NAM) therapy approach includes reduction of the size of the intraoral alveolar cleft as well as positioning of the surrounding deformed soft tissues and cartilages. In a bilateral cleft patient, NAM, along with columellar elongation, eliminates the need for columellar lengthening surgery. Thus the frequent surgical intervention to achieve the desired esthetic results can be avoided...
January 2018: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
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