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https://www.readbyqxmd.com/read/28343332/posterior-elements-disruption-with-hybrid-constructs-in-ais-patients-is-there-an-impact-on-proximal-junctional-kyphosis
#1
S Ghailane, Sebastien Pesenti, E Peltier, E Choufani, B Blondel, J L Jouve
PURPOSE: Proximal junctional kyphosis (PJK) is a frequent proximal adjacent segment disease following spinal fusion in adolescent idiopathic scoliosis (AIS) and its rate has been estimated to 28% in the literature. The etiology is multifactorial, and risk factors associated with PJK are controversial. The aim of this study was to demonstrate that the disruption of muscular and bony tissue above the upper instrumented vertebra (UIV) during surgery does not increase the rate of PJK in patients undergoing posterior fusion for adolescent idiopathic scoliosis...
March 25, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28340431/utility-of-repetitive-nerve-stimulation-test-for-als-diagnosis
#2
Yuki Hatanaka, Mana Higashihara, Takashi Chiba, Yosuke Miyaji, Yasuomi Kawamura, Masahiro Sonoo
OBJECTIVE: Decremental responses in the repetitive nerve stimulation (RNS) test in amyotrophic lateral sclerosis (ALS) patients have been reported, although their possible diagnostic role has received little investigation. We investigated their diagnostic role in differentiation between ALS and cervical spondylotic amyotrophy (CSA), an important ALS mimic especially in Japan. METHODS: Patients were prospectively enrolled and the diagnosis was confirmed by follow-up...
March 6, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28340163/does-cervical-interlaminar-epidural-steroid-injection-with-low-dose-lidocaine-cause-objective-upper-extremity-weakness-a-preliminary-study
#3
Zachary L McCormick, Ariana Nelson, Mark C Kendall, Robert J McCarthy, Geeta Nagpal, David R Walega
Objective. : Low-dose local anesthetic is often used in cervical interlaminar epidural steroid injections (CIESI), yet its effect on upper extremity strength has not been studied. The presence of consequent weakness has potential implications for postprocedure safety. This study aimed to determine whether low-dose lidocaine in a C7-T1 CIESI causes objective weakness. Design. : Prospective case series. Setting. : Academic pain center...
March 18, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28340157/cervical-lateral-glide-neural-mobilization-is-effective-in-treating-cervicobrachial-pain-a-randomized-waiting-list-controlled-clinical-trial
#4
David Rodríguez-Sanz, César Calvo-Lobo, Francisco Unda-Solano, Irene Sanz-Corbalán, Carlos Romero-Morales, Daniel López-López
Background.:  Cervicobrachial pain (CP) is a high-incidence and prevalent condition. Cervical lateral glide (CLG) is a firstline treatment of CP. There is a current lack of enough high-quality randomized controlled double-blind clinical trials that measure the effectiveness of neural tissue mobilization techniques such as the CLG and its specific effect over CP. Objectives.:  The aim of the present study was to assess the effect of CLG neural mobilization in treating subjects who suffer from CP, compared with the complete absence of treatment...
March 13, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28335890/cervical-cancer-incidence-in-elderly-women-biology-or-screening-history
#5
Elsebeth Lynge, Stefan Lönnberg, Sven Törnberg
AIM: In many countries, the age-specific pattern of cervical cancer incidence is currently bipolar with peaks at for instance 45 and 65 years of age. Consequently, a large proportion of cervical cancer cases are presently diagnosed in women above the screening age. The purpose of the study was to determine whether this bipolar pattern in age-specific incidence of cervical cancer reflects underlying biology or can be explained by the fact that the data come from birth cohorts with different screening histories...
March 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28334837/clinical-outcome-of-definitive-radiation-therapy-for-superficial-esophageal-cancer
#6
Yutaro Koide, Takeshi Kodaira, Hiroyuki Tachibana, Natsuo Tomita, Chiyoko Makita, Makoto Itoh, Tetsuya Abe, Kei Muro, Masahiro Tajika, Yasumasa Niwa, Yoshiyuki Itoh, Shinji Naganawa
Objective: To analyze the clinical outcome of concurrent chemoradiotherapy in superficial esophageal cancer patients. Methods: We retrospectively analyzed data for 123 patients with superficial esophageal cancer who received external beam radiotherapy without intracavitary brachytherapy plus systemic chemotherapy during 1998-2015. Elective nodal irradiation was not performed. The dosage to planning treatment volume was 60 Gy in 30 fractions. The main outcome measure was overall survival...
February 23, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28334358/ranges-of-cervical-intervertebral-disc-deformation-during-an-in-vivo-dynamic-flexion-extension-of-the-neck
#7
Yan Yu, Haiqing Mao, Jing-Sheng Li, Tsung-Yuan Tsai, Liming Cheng, Kirkham B Wood, Guoan Li, Thomas D Cha
While abnormal loading is widely believed to cause cervical spine disc diseases, in-vivo cervical disc deformation during dynamic neck motion has not been well delineated. This study investigated the range of cervical disc deformation during an in-vivo functional flexion-extension of the neck. Ten asymptomatic human subjects were tested using a combined dual fluoroscopic imaging system and MRI based 3D modeling technique. Overall disc deformation was determined using the changes of the space geometry between upper and lower endplates of each intervertebral segment (C3/4, C4/5, C5/6 and C6/7)...
March 23, 2017: Journal of Biomechanical Engineering
https://www.readbyqxmd.com/read/28331643/hemifacial-pain-and-hemisensory-disturbance-referred-from-occipital-neuralgia-caused-by-pathological-vascular-contact-of-the-greater-occipital-nerve
#8
Byung-Chul Son, Jin-Gyu Choi
Here we report a unique case of chronic occipital neuralgia caused by pathological vascular contact of the left greater occipital nerve. After 12 months of left-sided, unremitting occipital neuralgia, a hypesthesia and facial pain developed in the left hemiface. The decompression of the left greater occipital nerve from pathological contacts with the occipital artery resulted in immediate relief for hemifacial sensory change and facial pain, as well as chronic occipital neuralgia. Although referral of pain from the stimulation of occipital and cervical structures innervated by upper cervical nerves to the frontal head of V1 trigeminal distribution has been reported, the development of hemifacial sensory change associated with referred trigeminal pain from chronic occipital neuralgia is extremely rare...
2017: Case Reports in Neurological Medicine
https://www.readbyqxmd.com/read/28331271/adenoid-cystic-carcinoma-of-trachea
#9
Ashish Varghese, Swati Suneha, John C Watkinson
Adenoid cystic carcinoma (ACC) is the second most common primary malignant tumor of the trachea, after squamous cell carcinoma. Patients present with upper airway obstructive symptoms and signs including dyspnoea, cough, haemoptysis, and stridor which are often insidious, delaying diagnosis and optimal management. Described here is an unusual case of primary ACC cervical trachea with concomitant micropapillary thyroid carcinoma (microPTC) in a middle-aged lady presenting with cough and breathing difficulty since 3 months...
February 2017: Indian Journal of Surgery
https://www.readbyqxmd.com/read/28329748/extensive-multilevel-split-laminotomy-for-debulking-a-cervicothoracolumbar-nondysraphic-intramedullary-spinal-cord-lipoma-in-a-2-month-old-infant
#10
Ha Son Nguyen, Sean Lew
INTRODUCTION: Laminectomy is the traditional approach for posterior exposure of the spinal canal for tumor resection. Another technique is split laminotomy, which entails the division and retraction of the spinous processes and laminae to access the thecal sac. This technique has been employed for small-segment exposures, but not extensively explored for long-segment exposures. CASE: A 2-month-old male presented with progressive right-leg plegia. MRI of the spine revealed a large, intramedullary spinal-cord lipoma extending from C6 to L5...
March 23, 2017: Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28327909/clinical-outcomes-following-surgical-management-of-coexisting-parkinson-disease-and-cervical-spondylotic-myelopathy
#11
Roy Xiao, Jacob A Miller, Daniel Lubelski, Thomas E Mroz, Edward C Benzel, Ajit A Krishnaney, Andre Machado
BACKGROUND: Distinguishing the causes of weakness and gait instability in patients with Parkinson disease (PD) and cervical spondylotic myelopathy (CSM) is a diagnostic and therapeutic challenge due to symptomatic similarities. No study has reported outcomes following decompression in patients with PD and CSM. OBJECTIVE: To report outcomes following cervical decompression for patients with coexisting PD and CSM. METHODS: A retrospective matched cohort study of all patients with PD and CSM undergoing cervical decompression at a tertiary-care center between January 1996 and December 2014 was conducted...
February 2, 2017: Neurosurgery
https://www.readbyqxmd.com/read/28327094/finger-tapping-impairments-are-highly-sensitive-for-evaluating-upper-motor-neuron-lesions
#12
Afsaneh Shirani, Braeden D Newton, Darin T Okuda
BACKGROUND: Identifying highly sensitive and reliable neurological exam components are crucial in recognizing clinical deficiencies. This study aimed to investigate finger tapping performance differences between patients with CNS demyelinating lesions and healthy control subjects. METHODS: Twenty-three patients with multiple sclerosis or clinically isolated syndrome with infratentorial and/or cervical cord lesions on MRI, and 12 healthy controls were videotaped while tapping the tip of the index finger against the tip and distal crease of the thumb using both the dominant and non-dominant hand...
March 21, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28324978/influence-of-electrode-configuration-on-the-electric-field-distribution-during-transcutaneous-spinal-direct-current-stimulation-of-the-cervical-spine
#13
Sofia R Fernandes, Ricardo Salvador, Cornelia Wenger, Mamede A de Carvalho, Pedro C Miranda
Transcutaneous spinal direct current stimulation (tsDCS) is a recent technique with promising neuromodulatory effects on spinal neuronal circuitry. The main objective of the present study was to perform a finite element analysis of the electric field distribution in tsDCS in the cervical spine region, with varying electrode configurations and geometry. A computational model of a human trunk was generated with nine tissue meshes. Three electrode configurations were tested: A) rectangular saline-soaked sponge target and return electrodes placed over C3 and T3 spinous processes, respectively; B1) circular saline-soaked sponge target and return electrodes placed over C7 spinous process and right deltoid muscle, respectively; B2) same configuration as B1, considering circular shaped electrodes with sponge and rubber layers and a small circular connector on the top surface...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28323089/enhancement-of-erk-phosphorylation-and-photic-responses-in-vc-c1-neurons-of-a-migraine-model
#14
Suzuro Hitomi, Akiko Okada-Ogawa, Yuka Sato, Ikuko Shibuta-Suzuki, Masamichi Shinoda, Yoshiki Imamura, Kentaro Ono, Koichi Iwata
Although it is well known that migraine pain is enhanced by photic stimulation of the eye, the mechanisms underlying this response are not yet understood. Noxious stimulation to the dura is known to activate trigeminal spinal subnucleus caudalis and upper cervical spinal cord (Vc/C1) neurons, causing migraine pain. Intense photic stimulation to the eye is also known to activate certain Vc/C1 neurons, thus increasing migraine pain. In this study, we hypothesized that Vc/C1 neurons receiving noxious dural input would be further activated by intense photic stimulation, resulting in the enhancement of migraine pain...
March 18, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28319883/the-influence-of-a-depressed-scapular-alignment-on-upper-limb-neural-tissue-mechanosensitivity-and-local-pressure-pain-sensitivity
#15
Patricia Martínez-Merinero, Enriqe Lluch, Tomas Gallezo-Izquierdo, Daniel Pecos-Martín, Gustavo Plaza-Manzano, Susana Nuñez-Nagy, Deborah Falla
BACKGROUND: A depressed scapular alignment could lead to prolonged and repetitive stress or compression of the brachial plexus, resulting in sensitization of neural tissue. However, no study has investigated the influence of alignment of the scapulae on sensitization of upper limb neural tissue in otherwise asymptomatic people. In this case-control study, we investigate the influence of a depressed scapular alignment on mechanosensitivity of the upper limb peripheral nervous system as well as pressure pain thresholds (PPT)...
March 10, 2017: Musculoskelet Sci Pract
https://www.readbyqxmd.com/read/28317557/the-role-of-allometry-and-posture-in-the-evolution-of-the-hominin-subaxial-cervical-spine
#16
Mikel Arlegi, Asier Gómez-Olivencia, Lou Albessard, Ignacio Martínez, Antoine Balzeau, Juan Luis Arsuaga, Ella Been
Cervical vertebrae not only protect the spinal cord but also are the insertion and origin points for muscles related to the movement of the head, upper limb, and trunk, among others, and are thus important elements in primate evolution. While previous work has been undertaken on the first two cervical vertebrae, there is a dearth of studies on the subaxial cervical spine in hominines. In this paper, we provide detailed morphological information on two important aspects of the subaxial cervical vertebrae (C3 - C7): mid-sagittal morphology and superior facet orientation...
March 2017: Journal of Human Evolution
https://www.readbyqxmd.com/read/28317555/the-cervical-spine-of-australopithecus-sediba
#17
Marc R Meyer, Scott A Williams, Peter Schmid, Steven E Churchill, Lee R Berger
Cervical vertebrae are rare in the early hominin fossil record, presenting a challenge for understanding the evolution of the neck and head carriage in hominin evolution. Here, we examine the cervical vertebrae of Australopithecus sediba, which unlike other South African taxa is known from associated cervical vertebrae. The A. sediba cervical vertebrae exhibit human-like values for wedging, pedicle cross-sectional areas, and articular facet heights, indicating reduced ventral loading relative to African apes...
March 2017: Journal of Human Evolution
https://www.readbyqxmd.com/read/28317439/patterns-of-cervical-and-masticatory-impairment-in-subgroups-of-people-with-temporomandibular-disorders-an-explorative-approach-based-on-factor-analysis
#18
Nikolaus Ballenberger, Harry von Piekartz, Mira Danzeisen, Toby Hall
OBJECTIVES: To identify clinical patterns of impairment affecting the cervical spine and masticatory systems in different subcategories of temporomandibular disorder (TMD) by an explorative data-driven approach. METHODS: For this observational study, 144 subjects were subdivided according to Research Diagnostic Criteria for TMDs into: Healthy controls, temporomandibular joint (TMJ) signs without symptoms, TMJ affected, temporomandibular muscles affected, or TMJ and muscles affected...
March 20, 2017: Cranio: the Journal of Craniomandibular Practice
https://www.readbyqxmd.com/read/28316850/a-report-of-two-cases-of-age-related-changes-in-cervical-morphology-in-postmenopausal-women-with-vaginal-adenosis
#19
Marguerite B Vigliani
This paper presents two cases of women who had extensive vaginal adenosis from prenatal DES exposure, extending almost halfway down the vaginal canal. Both women were followed for decades with annual exams and Pap smears until after menopause. Clinical examination in both cases initially showed an absent pars vaginalis of the cervix, vaginal adenosis, and shallowness of the fornices. Several decades of annual exams showed these stigmata of DES exposure gradually disappear as the upper vagina progressively contracted...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28304238/remote-motor-system-metabolic-profile-and-surgery-outcome-in-cervical-spondylotic-myelopathy
#20
Sorin C Craciunas, Mircea R Gorgan, Bogdan Ianosi, Phil Lee, Joseph Burris, Carmen M Cirstea
OBJECTIVE In patients with cervical spondylotic myelopathy (CSM), the motor system may undergo progressive functional/structural changes rostral to the lesion, and these changes may be associated with clinical disability. The extent to which these changes have a prognostic value in the clinical recovery after surgical treatment is not yet known. In this study, magnetic resonance spectroscopy (MRS) was used to test 2 primary hypotheses. 1) Based on evidence of corticospinal and spinocerebellar, rubro-, or reticulospinal tract degeneration/dysfunction during chronic spinal cord compression, the authors hypothesized that the metabolic profile of the primary motor cortices (M1s) and cerebellum, respectively, would be altered in patients with CSM, and these alterations would be associated with the extent of the neurological disabilities...
March 17, 2017: Journal of Neurosurgery. Spine
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