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https://www.readbyqxmd.com/read/28917789/chemometric-optimization-of-the-extraction-and-derivatization-of-parabens-for-their-determination-in-water-samples-by-rotating-disk-sorptive-extraction-and-gas-chromatography-mass-spectrometry
#1
Mercedes Becerra-Herrera, Valentina Miranda, Daniel Arismendi, Pablo Richter
A combination of rotating disk sorptive extraction (RDSE) using Oasis® HLB as the sorbent phase and gas chromatography mass spectrometry (GC-MS) has been performed for the determination of four of the most widely used parabens: methylparaben, ethylparaben, propylparaben and n-butylparaben. The extraction and derivatization of the analytes in water samples were optimized by using factorial (screening) and Doehlert designs, thus reducing the number of analyses with the concomitant reduction of time, reagents, waste, samples and cost...
January 1, 2018: Talanta
https://www.readbyqxmd.com/read/28917340/esophageal-dilation-for-eosinophilic-esophagitis-it-s-safe-why%C3%A2-aren-t-we-doing-more-dilations
#2
EDITORIAL
Joel E Richter
No abstract text is available yet for this article.
October 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28917270/cancer-related-fatigue-in-adolescents-and-young-adults-a-systematic-review-of-the-literature
#3
REVIEW
E Nowe, Y Stöbel-Richter, A Sender, K Leuteritz, M Friedrich, K Geue
Adolescents and young adults with cancer (AYA) represent a specific age cohort dealing with the disease in a stage of life characterized by development, upheavals, and establishment. The aim of this study was to point out the state of research on how AYA are affected by cancer-related fatigue (CRF). RESULTS: Twelve articles were included. CRF was found to be higher in AYA than in either of the comparison groups, healthy peers and older cancer patients. Most included studies did not measure CRF with multidimensional, fatigue-specific instruments...
October 2017: Critical Reviews in Oncology/hematology
https://www.readbyqxmd.com/read/28916263/autophagy-dependent-generation-of-free-fatty-acids-is-critical-for-normal-neutrophil-differentiation
#4
Thomas Riffelmacher, Alexander Clarke, Felix C Richter, Amanda Stranks, Sumeet Pandey, Sara Danielli, Philip Hublitz, Zhanru Yu, Errin Johnson, Tobias Schwerd, James McCullagh, Holm Uhlig, Sten Eirik W Jacobsen, Anna Katharina Simon
Neutrophils are critical and short-lived mediators of innate immunity that require constant replenishment. Their differentiation in the bone marrow requires extensive cytoplasmic and nuclear remodeling, but the processes governing these energy-consuming changes are unknown. While previous studies show that autophagy is required for differentiation of other blood cell lineages, its function during granulopoiesis has remained elusive. Here, we have shown that metabolism and autophagy are developmentally programmed and essential for neutrophil differentiation in vivo...
September 1, 2017: Immunity
https://www.readbyqxmd.com/read/28916132/the-association-between-elevated-blood-lead-levels-and-violent-behavior-during-late-adolescence-the-south-african-birth-to-twenty-plus-cohort
#5
Palesa Nkomo, Angela Mathee, Nisha Naicker, Jacky Galpin, Linda M Richter, Shane A Norris
Epidemiological studies have shown the adverse neuro-behavioral health effects of lead exposure among children, in particular. However, there is lack evidence in this regard from developing countries. The main aim of this study was to assess the association between blood lead levels (BLLs) during early adolescence and violent behavior in late adolescence. Our study sample from the Birth to Twenty Plus cohort in Soweto-Johannesburg, South Africa included 1332 study participants (684 females). BLLs were measured using blood samples collected at age 13years...
September 12, 2017: Environment International
https://www.readbyqxmd.com/read/28915861/informed-decision-making-with-and-for-people-with-dementia-efficacy-of-the-prodecide-education-program-for-legal-representatives-protocol-of-a-randomized-controlled-trial-prodecide-rct
#6
Julia Lühnen, Burkhard Haastert, Ingrid Mühlhauser, Tanja Richter
BACKGROUND: In Germany, the guardianship system provides adults who are no longer able to handle their own affairs a court-appointed legal representative, for support without restriction of legal capacity. Although these representatives only rarely are qualified in healthcare, they nevertheless play decisive roles in the decision-making processes for people with dementia. Previously, we developed an education program (PRODECIDE) to address this shortcoming and tested it for feasibility...
September 15, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28915261/simultaneous-determination-of-3-hydroxypropionic-acid-methylmalonic-acid-and-methylcitric-acid-in-dried-blood-spots-second-tier-lc-ms-ms-assay-for-newborn-screening-of-propionic-acidemia-methylmalonic-acidemias-and-combined-remethylation-disorders
#7
Péter Monostori, Glynis Klinke, Sylvia Richter, Ákos Baráth, Ralph Fingerhut, Matthias R Baumgartner, Stefan Kölker, Georg F Hoffmann, Gwendolyn Gramer, Jürgen G Okun
BACKGROUND AND AIMS: Increased propionylcarnitine levels in newborn screening are indicative for a group of potentially severe disorders including propionic acidemia (PA), methylmalonic acidemias and combined remethylation disorders (MMACBL). This alteration is relatively non-specific, resulting in the necessity of confirmation and differential diagnosis in subsequent tests. Thus, we aimed to develop a multiplex approach for concurrent determination of 3-hydroxypropionic acid, methylmalonic acid and methylcitric acid from the same dried blood spot (DBS) as in primary screening (second-tier test)...
2017: PloS One
https://www.readbyqxmd.com/read/28913929/high-nutrition-risk-is-associated-with-higher-risk-of-dysphagia-in-advanced-age-adults-newly-admitted-to-hospital
#8
Amy Popman, Marilize Richter, Jacqueline Allen, Carol Wham
AIM: To establish the prevalence of nutrition risk and associated risk factors among adults of advanced age newly admitted to hospital. METHODS: A cross-sectional study was undertaken in adults aged over 85 years admitted to one of two hospital wards in Auckland within the previous 5 days. An interviewer-administered questionnaire was used to establish participant's socio-demographic and health characteristics. Markers of body composition and muscle strength were collected...
September 15, 2017: Nutrition & Dietetics: the Journal of the Dietitians Association of Australia
https://www.readbyqxmd.com/read/28911799/effects-of-glucocorticoids-on-stratum-corneum-lipids-and-function-in-human-skin-a-detailed-lipidomic-analysis
#9
Mads A Røpke, Cristina Alonso, Sora Jung, Hanne Norsgaard, Claudia Richter, Maxim E Darvin, Thomas Litman, Annika Vogt, Jürgen Lademann, Ulrike Blume-Peytavi, Jan Kottner
BACKGROUND: Topical glucocorticoids (GCs) are known to induce atrophy of human skin including thinning of epidermal and dermal compartments by influencing keratinocyte proliferation and synthesis of extracellular matrix proteins. GCs are also known to reduce skin barrier integrity but little is known about the changes in lipid composition in human skin following topical administration of GCs. OBJECTIVE: This study investigated the effects of GCs on stratum corneum (SC) function and lipid profile of human skin in vivo...
August 26, 2017: Journal of Dermatological Science
https://www.readbyqxmd.com/read/28911006/ghrelin-serum-concentrations-are-associated-with-treatment-response-during-lithium-augmentation-of-antidepressants
#10
Roland Ricken, Sandra Bopp, Peter Schlattmann, Hubertus Himmerich, Tom Bschor, Christoph Richter, Samuel Elstner, Thomas J Stamm, Brigitte Schulz-Ratei, Alexandra Lingesleben, Friedel M Reischies, Philipp Sterzer, Stefan Borgwardt, Michael Bauer, Andreas Heinz, Rainer Hellweg, Undine E Lang, Mazda Adli
Background: Lithium augmentation of antidepressants is an effective strategy in treatment-resistant depression. The proteohormone ghrelin is thought to be involved in the pathophysiology of depression. The purpose of this study was to investigate the association of treatment response with the course of ghrelin levels during lithium augmentation. Method: Ghrelin serum concentrations and severity of depression were measured in 85 acute depressive patients before and after 4 weeks of lithium augmentation...
September 1, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28903540/molecular-signatures-that-can-be-transferred-across-different-omics-platforms
#11
M Altenbuchinger, P Schwarzfischer, T Rehberg, J Reinders, Ch W Kohler, W Gronwald, J Richter, M Szczepanowski, N Masqué-Soler, W Klapper, P J Oefner, R Spang
No abstract text is available yet for this article.
September 1, 2017: Bioinformatics
https://www.readbyqxmd.com/read/28903367/exploratory-investigation-of-psca-protein-expression-in-primary-breast-cancer-patients-reveals-a-link-to-her2-neu-overexpression
#12
Theresa Link, Friederike Kuithan, Armin Ehninger, Jan Dominik Kuhlmann, Michael Kramer, Andreas Werner, Axel Gatzweiler, Barbara Richter, Gerhard Ehninger, Gustavo Baretton, Michael Bachmann, Pauline Wimberger, Katrin Friedrich
BACKGROUND: Prostate stem cell antigen (PSCA) has been suggested as biomarker and therapeutic target for prostate cancer. Recent advances showed that PSCA is up-regulated in other cancer entities, such as bladder or pancreatic cancer. However, the clinical relevance of PSCA-expression in breast cancer patients has not yet been established and is therefore addressed by the current study. METHODS: PSCA-protein expression was assessed in 405 breast cancer patients, using immunohistochemistry (PSCA antibody MB1) and tissue microarrays...
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28902621/online-teaching-efficacy-a-product-of-professional-development-and-ongoing-support
#13
Sally Richter, Lynda Idleman
The purpose of the pilot study was to investigate the perceptions of online teaching efficacy of nursing faculty who teach courses in which 51% or more of the content is offered online. Bandura's psychological construct of self-efficacy served as the conceptual framework. The research survey was administered to nursing faculty in a state university system located in the southeastern United States of America, plus two private universities. The Michigan Nurse Educator's Sense of Efficacy for Online Teaching Scale, which contains 32 items that measure how nurse educators judge their current capabilities for teaching online nursing courses, was used to gather data...
August 22, 2017: International Journal of Nursing Education Scholarship
https://www.readbyqxmd.com/read/28900593/deposition-of-exchange-coupled-dinickel-complexes-on-gold-substrates-utilizing-ambidentate-mercapto-carboxylato-ligands
#14
Martin Börner, Laura Blömer, Marcus Kischel, Peter Richter, Georgeta Salvan, Dietrich R T Zahn, Pablo F Siles, Maria E N Fuentes, Carlos C B Bufon, Daniel Grimm, Oliver G Schmidt, Daniel Breite, Bernd Abel, Berthold Kersting
The chemisorption of magnetically bistable transition metal complexes on planar surfaces has recently attracted increased scientific interest due to its potential application in various fields, including molecular spintronics. In this work, the synthesis of mixed-ligand complexes of the type [Ni(II)2L(L')](ClO4), where L represents a 24-membered macrocyclic hexaazadithiophenolate ligand and L' is a ω-mercapto-carboxylato ligand (L' = HS(CH2)5CO2(-) (6), HS(CH2)10CO2(-) (7), or HS(C6H4)2CO2(-) (8)), and their ability to adsorb on gold surfaces is reported...
2017: Beilstein Journal of Nanotechnology
https://www.readbyqxmd.com/read/28898358/relevance-of-the-implementation-of-teeth-in-three-dimensional-vocal-tract-models
#15
Louisa Traser, Peter Birkholz, Tabea Viktoria Flügge, Robert Kamberger, Michael Burdumy, Bernhard Richter, Jan Gerrit Korvink, Matthias Echternach
Purpose: Recently, efforts have been made to investigate the vocal tract using magnetic resonance imaging (MRI). Due to technical limitations, teeth were omitted in many previous studies on vocal tract acoustics. However, the knowledge of how teeth influence vocal tract acoustics might be important in order to estimate the necessity of implementing teeth in vocal tract models. The aim of this study was therefore to estimate the effect of teeth on vocal tract acoustics. Method: The acoustic properties of 18 solid (3-dimensional printed) vocal tract models without teeth were compared to the same 18 models including teeth in terms of resonance frequencies (fRn)...
September 12, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28895846/in%C3%A2-vivo-hematopoietic-stem-cell-transduction
#16
REVIEW
Maximilian Richter, Daniel Stone, Carol Miao, Olivier Humbert, Hans-Peter Kiem, Thalia Papayannopoulou, André Lieber
Current protocols for hematopoietic stem cell (HSC) gene therapy, involving the transplantation of ex vivo lentivirus vector-transduced HSCs into myeloablated recipients, are complex and not without risk for the patient. In vivo HSC gene therapy can be achieved by the direct modification of HSCs in the bone marrow after intraosseous injection of gene delivery vectors. A recently developed approach involves the mobilization of HSCs from the bone marrow into peripheral the blood circulation, intravenous vector injection, and re-engraftment of genetically modified HSCs in the bone marrow...
October 2017: Hematology/oncology Clinics of North America
https://www.readbyqxmd.com/read/28895615/-methamphetamine-use-in-central-germany-a-qualitative-study-on-consumer-groups-and-motives-from-the-experts-perspective
#17
Laura Hoffmann, Nadine Schumann, Matthias Richter
Background Methamphetamine is one of the most consumed illegal drugs worldwide. In Germany, Methamphetamine shows the highest rates of growth in comparison to other illegal substances in recent years. Particularly Central Germany has been struck by a high rise in consumption. International studies indicate that there is no specific group of people that can be identified as Methamphetamine users. Different consumption patterns in terms of Methamphetamine use can be identified within various social groups. This qualitative study will explore different consumer groups among methamphetamine users, their motives, and how they differ by drug addiction type...
September 11, 2017: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/28895613/-the-g-score-a-short-questionnaire-for-the-measurement-of-subjective-physical-health
#18
Juliana Schneider, Markus Zenger, Elmar Brähler, Yve Stöbel-Richter, Hendrik Berth
Aim The measurement of subjective physical health is important in clinical settings as well as for research purposes. In the present paper, the psychometric properties of the G-Score, a 4 item screening questionnaire for the self-assessment of one's physical health, is explored. Methods The Objectivity, validity and reliability were estimated. Moreover, an item analysis and a suitable cut-off-value for the differentiation between healthy and presumably ill subjects were conducted. Data from the Saxony Longitudinal Study ("Sächsische Längsschnittstudie") 1998-2013 were analysed (N=324-417 healthy individuals)...
September 11, 2017: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/28892969/fistulating-richter-s-hernia-of-groin-with-necrotizing-soft-tissue-infection-a-lethal-combination
#19
Shibojit Talukder, Ashish Gupta, Basant Narayan Singh, Lileswar Kaman, P Abhinaya Reddy
Strangulation of groin hernia can result in significant morbidity and mortality. Spontaneous external fistulation following strangulation is rare and typically occurs with Richter's hernia. Spreading Necrotizing Soft Tissue Infection (NSTI) secondary to Enterocutaneous Fistula (ECF) is an ominous sign, further worsening its prognosis. Early diagnosis and prompt surgical treatment is crucial to improve outcome. Herewith the authors are presenting a case of neglected inguinal hernia. It was complicated with ECF formation and rapidly spreading NSTI of flank...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28892487/transcriptome-sequencing-and-delimitation-of-sympatric-oscarella-species-o-carmela-and-o-pearsei-sp-nov-from-california-usa
#20
Alexander V Ereskovsky, Daniel J Richter, Dennis V Lavrov, Klaske J Schippers, Scott A Nichols
The homoscleromorph sponge Oscarella carmela, first described from central California, USA is shown to represent two superficially similar but both morphologically and phylogenetically distinct species that are co-distributed. We here describe a new species as Oscarella pearsei, sp. nov. and re-describe Oscarella carmela; the original description was based upon material from both species. Further, we correct the identification of published genomic/transcriptomic resources that were originally attributed to O...
2017: PloS One
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