keyword
MENU ▼
Read by QxMD icon Read
search

Richters

keyword
https://www.readbyqxmd.com/read/29785728/ultrafast-capillary-electrophoresis-method-for-the-simultaneous-determination-of-ammonium-and-diphenhydramine-in-pharmaceutical-samples
#1
Brenda M C Costa, Mariana C Marra, Thiago C Oliveira, Rodrigo A A Munoz, Alex D Batista, Claudimir L do Lago, Eduardo M Richter
Ammonium and diphenhydramine are active ingredients commonly found in the same pharmaceutical preparations. We report for the first time a sub-minute method for the simultaneous determination of ammonium and diphenhydramine. The method is based on capillary electrophoresis with capacitively coupled contactless conductivity detection. Both analytes can be quantified in a single run (∼80 injections h-1 ) using 30 mmol L-1 2-(N-morpholino)ethanesulfonic acid and 15 mmol L-1 lithium hydroxide (pH = 6.0) as a background electrolyte...
May 22, 2018: Journal of Separation Science
https://www.readbyqxmd.com/read/29783101/chondrogenic-differentiation-in-vitro-of-hipscs-activates-pathways-engaged-in-limb-development
#2
Ewelina Stelcer, Katarzyna Kulcenty, Marcin Rucinski, Karol Jopek, Magdalena Richter, Tomasz Trzeciak, Wiktoria Maria Suchorska
No abstract text is available yet for this article.
May 18, 2018: Stem Cell Research
https://www.readbyqxmd.com/read/29781496/a-universal-platform-for-selection-and-high-resolution-phenotypic-screening-of-bacterial-mutants-using-the-nanowell-slide
#3
H Antypas, M Veses-Garcia, E Weibull, H Andersson-Svahn, A Richter-Dahlfors
The Petri dish and microtiter plate are the golden standard for selection and screening of bacteria in microbiological research. To improve on the limited resolution and throughput of these methods, we developed a universal, user-friendly platform for selection and high-resolution phenotypic screening based on the nanowell slide. This miniaturized platform has an optimal ratio between throughput and assay complexity, holding 672 nanowells of 500 nl each. As monoclonality is essential in bacterial genetics, we used FACS to inoculate each nanowell with a single bacterium in 15 min...
May 21, 2018: Lab on a Chip
https://www.readbyqxmd.com/read/29779262/-salivary-exrna-biomarkers-to-detect-gingivitis-and-monitor-disease-regression
#4
Karolina Elżbieta Kaczor-Urbanowicz, Harsh M Trivedi, Patricia O Lima, Paulo M Camargo, William V Giannobile, Tristan R Grogan, Frederico O Gleber-Netto, Yair Whiteman, Feng Li, Hyo Jung Lee, Karan Dharia, Katri Aro, Carmen Martin Carerras-Presas, Saarah Amuthan, Manjiri Vartak, David Akin, Hiba Al-Adbullah, Kanika Bembey, Perry R Klokkevold, David Elashoff, Virginia Monsul Barnes, Rose Richter, William DeVizio, James G Masters, David Wong
AIM: This study tests the hypothesis that salivary extracellular RNA (exRNA) biomarkers can be developed for gingivitis detection and monitoring disease regression. MATERIALS AND METHODS: Salivary exRNA biomarker candidates were developed from a total of 100 gingivitis and non-gingivitis individuals using Affymetrix's expression microarrays. The top ten differentially expressed exRNAs were tested in a clinical cohort to determine if the discovered salivary exRNA markers for gingivitis were associated with clinical gingivitis and disease regression...
May 19, 2018: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/29778517/production-and-efficacy-of-a-low-cost-recombinant-pneumococcal-protein-polysaccharide-conjugate-vaccine
#5
Jenny A Herbert, Emily J Kay, Sian E Faustini, Alex Richter, Sherif Abouelhadid, Jon Cuccui, Brendan Wren, Timothy J Mitchell
Streptococcus pneumoniae is the leading cause of bacterial pneumonia. Although this is a vaccine preventable disease, S. pneumoniae still causes over 1 million deaths per year, mainly in children under the age of five. The biggest disease burden is in the developing world, which is mainly due to unavailability of vaccines due to their high costs. Protein polysaccharide conjugate vaccines are given routinely in the developed world to children to induce a protective antibody response against S. pneumoniae. One of these vaccines is Prevnar13, which targets 13 of the 95 known capsular types...
May 16, 2018: Vaccine
https://www.readbyqxmd.com/read/29775711/co-expression-purification-and-characterization-of-the-lipase-and-foldase-of-burkholderia-contaminans-lteb11
#6
Robson Carlos Alnoch, Adriano Alves Stefanello, Viviane de Paula Martini, Jeferson Luiz Richter, Cesar Mateo, Emanuel Maltempi de Souza, David Alexander Mitchell, Marcelo Muller-Santos, Nadia Krieger
Genes encoding lipase LipBC (lipA) and foldase LifBC (lipB) were identified in the genome of Burkholderia contaminans LTEB11. Analysis of the predicted amino acid sequence of lipA showed its high identity with lipases from Pseudomonas luteola (91%), Burkholderia cepacia (96%) and Burkholderia lata (97%), and classified LipBC lipase in the lipase subfamily I.2. The genes lipA and lipB were amplified and cloned into expression vectors pET28a(+) and pT7-7, respectively. His-tagged LipBC and native LifBC were co-expressed in Escherichia coli and purified...
May 15, 2018: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29775423/successfully-striving-for-happiness-socially-engaged-pursuits-predict-increases-in-life-satisfaction
#7
Julia M Rohrer, David Richter, Martin Brümmer, Gert G Wagner, Stefan C Schmukle
Happiness is considered a highly desirable attribute, but whether or not individuals can actively steer their lives toward greater well-being is an open empirical question. In this study, respondents from a representative German sample reported, in text format, ideas for how they could improve their life satisfaction. We investigated which of these ideas predicted changes in life satisfaction 1 year later. Active pursuits per se-as opposed to statements about external circumstances or fortune-were not associated with changes in life satisfaction ( n = 1,178)...
May 1, 2018: Psychological Science
https://www.readbyqxmd.com/read/29774972/temperature-response-of-permafrost-soil-carbon-is-attenuated-by-mineral-protection
#8
Norman Gentsch, Birgit Wild, Robert Mikutta, Petr Čapek, Katka Diáková, Marion Schrumpf, Stephanie Turner, Cynthia Minnich, Frank Schaarschmidt, Olga Shibistova, Jörg Schnecker, Tim Urich, Antje Gittel, Hana Šantrůčková, Jiři Bárta, Nikolay Lashchinskiy, Roland Fuß, Andreas Richter, Georg Guggenberger
Climate change in Arctic ecosystems fosters permafrost thaw and makes massive amounts of ancient soil organic carbon (OC) available to microbial breakdown. However, fractions of the organic matter (OM) may be protected from rapid decomposition by their association with minerals. Little is known about the effects of mineral-organic associations (MOA) on the microbial accessibility of OM in permafrost soils and it is not clear which factors control its temperature sensitivity. In order to investigate if and how permafrost soil OC turnover is affected by mineral controls, the heavy fraction (HF) representing mostly MOA was obtained by density fractionation from 27 permafrost soil profiles of the Siberian Arctic...
May 18, 2018: Global Change Biology
https://www.readbyqxmd.com/read/29774926/an-anionic-shell-shields-a-cationic-core-allowing-for-uptake-and-release-of-polyelectrolytes-within-core-shell-responsive-microgels
#9
Arjan P H Gelissen, Andrea Scotti, Sarah K Turnhoff, Corinna Janssen, Aurel Radulescu, Andrij Pich, Andrey A Rudov, Igor I Potemkin, Walter Richtering
To realize carriers for drug delivery, cationic containers are required for anionic guests. Nevertheless, the toxicity of cationic carriers limits their practical use. In this study, we investigate a model system of polyampholyte N-isopropylacrylamide (NIPAM)-based microgels with a cationic core and an anionic shell to study whether the presence of a negative shell allows the cationic core to be shielded while still enabling the uptake and release of the anionic guest polyelectrolytes. These microgels are loaded with polystyrene sulfonate of different molecular weights to investigate the influence of their chain length on the uptake and release process...
May 18, 2018: Soft Matter
https://www.readbyqxmd.com/read/29770809/the-effect-of-earthquakes-on-the-housing-market-and-the-quality-of-life-in-the-province-of-groningen-the-netherlands
#10
Peter Boelhouwer, Harry van der Heijden
The Netherlands is not known for the occurrence of earthquakes. This is, however, a hot topic in the province of Groningen. Because of gas extraction, this area suffered from more than 1000 earthquakes. Most of them are not very intensive, but also bigger earthquakes of between 2 and 3 on the scale of Richter have been measured. In the last few years, thousands of houses are damaged, house prices have dropped, and the liveability is at stake. This paper pays attention to the effects of these earthquakes on the functioning of the housing market and the quality of life in the region...
2018: Journal of housing and the built environment: HBE
https://www.readbyqxmd.com/read/29770125/fgf23-actions-on-target-tissues-with-and-without-klotho
#11
REVIEW
Beatrice Richter, Christian Faul
Fibroblast growth factor (FGF) 23 is a phosphaturic hormone whose physiologic actions on target tissues are mediated by FGF receptors (FGFR) and klotho, which functions as a co-receptor that increases the binding affinity of FGF23 for FGFRs. By stimulating FGFR/klotho complexes in the kidney and parathyroid gland, FGF23 reduces renal phosphate uptake and secretion of parathyroid hormone, respectively, thereby acting as a key regulator of phosphate metabolism. Recently, it has been shown that FGF23 can also target cell types that lack klotho...
2018: Frontiers in Endocrinology
https://www.readbyqxmd.com/read/29769113/thinking-beyond-opisthorchis-viverrini-for-risk-of-cholangiocarcinoma-in-the-lower-mekong-region-a-systematic-review-and-meta-analysis
#12
REVIEW
Jennifer A Steele, Carsten H Richter, Pierre Echaubard, Parichat Saenna, Virginia Stout, Paiboon Sithithaworn, Bruce A Wilcox
BACKGROUND: Cholangiocarcinoma (CCA) is a fatal bile duct cancer associated with infection by the liver fluke, Opisthorchis viverrini, in the lower Mekong region. Numerous public health interventions have focused on reducing exposure to O. viverrini, but incidence of CCA in the region remains high. While this may indicate the inefficacy of public health interventions due to complex social and cultural factors, it may further indicate other risk factors or interactions with the parasite are important in pathogenesis of CCA...
May 17, 2018: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/29767752/stunting-at-24-months-is-not-related-to-incidence-of-overweight-through-young-adulthood-in-an-urban-south-african-birth-cohort
#13
Sara K Hanson, Richard J Munthali, Elizabeth A Lundeen, Linda M Richter, Shane A Norris, Aryeh D Stein
Background: The role that childhood stunting plays in the development of overweight and obesity later in life is not well understood, particularly in adolescence and young adulthood, because most studies have only followed up through midchildhood. Objective: The objective of this study was to examine the relation between stunting and age-specific patterns of overweight and obesity incidence from early childhood to young adulthood in the context of a country in the process of the nutrition transition while these children were growing up...
May 15, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29766208/-adequate-anti-infective-treatment-importance-of-individual-dosing-and-application
#14
A Brinkmann, A C Röhr, A Köberer, T Fuchs, W A Krüger, C König, D Richter, M A Weigand, O R Frey
Sepsis-induced changes in pharmacokinetic parameters are a well-known problem in intensive care medicine. Dosing of antibiotics in this setting is therefore challenging. Alterations to the substance-specific kinetics of anti-infective substances have an effect on the distribution and excretion processes in the body. Increased clearance and an increased distribution volume (Vd ) and particularly compromized organ function with reduced antibiotic elimination are often encountered in patients with sepsis. Renal replacement treatment, which is frequently used in intensive care medicine, represents a substantial intervention in this system...
May 15, 2018: Der Anaesthesist
https://www.readbyqxmd.com/read/29765520/histogram-analysis-parameters-of-dynamic-contrast-enhanced-magnetic-resonance-imaging-can-predict-histopathological-findings-including-proliferation-potential-cellularity-and-nucleic-areas-in-head-and-neck-squamous-cell-carcinoma
#15
Alexey Surov, Hans Jonas Meyer, Leonard Leifels, Anne-Kathrin Höhn, Cindy Richter, Karsten Winter
Our purpose was to analyze possible associations between histogram analysis parameters of dynamic contrast-enhanced magnetic resonance imaging DCE MRI and histopathological findings like proliferation index, cell count and nucleic areas in head and neck squamous cell carcinoma (HNSCC). 30 patients (mean age 57.0 years) with primary HNSCC were included in the study. In every case, histogram analysis parameters of Ktrans , Ve , and Kep were estimated using a mathlab based software. Tumor proliferation index, cell count, and nucleic areas were estimated on Ki 67 antigen stained specimens...
April 20, 2018: Oncotarget
https://www.readbyqxmd.com/read/29765103/identification-of-a-flagellar-protein-implicated-in-the-gravitaxis-in-the-flagellate-euglena-gracilis
#16
Adeel Nasir, Aude Le Bail, Viktor Daiker, Janine Klima, Peter Richter, Michael Lebert
Flagellated cells are of great evolutionary importance across animal and plant species. Unlike higher plants, flagellated cells are involved in reproduction of macro-algae as well as in early diverging land plants. Euglena gracilis is an emerging flagellated model organism. The current study reports that a specific calmodulin (CaM2) involved in gravitaxis of E. gracilis interacts with an evolutionary conserved flagellar protein, EgPCDUF4201. The subsequent molecular analysis showed clearly that EgPCDUF4201 is also involved in gravitaxis...
May 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29763335/nintedanib-in-severe-pulmonary-arterial-hypertension
#17
Manuel J Richter, Jan Ewert, Friedrich Grimminger, Hossein Ardeschir Ghofrani, Baktybek Kojonazarov, Aleksandar Petrovic, Werner Seeger, Ralph T Schermuly, Khodr Tello, Henning Gall
No abstract text is available yet for this article.
May 15, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29762141/pd-1-expression-in-chronic-lymphocytic-leukemia-small-lymphocytic-lymphoma-cll-sll-and-large-b-cell-richter-transformation-dlbcl-rt-a-characteristic-feature-of-dlbcl-rt-and-potential-surrogate-marker-for-clonal-relatedness
#18
Rong He, Wei Ding, David S Viswanatha, Dong Chen, Min Shi, Daniel Van Dyke, Shulan Tian, Linda N Dao, Sameer A Parikh, Tait D Shanafelt, Timothy G Call, Stephen M Ansell, Jose F Leis, Ming Mai, Curtis A Hanson, Karen L Rech
Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is a low-grade B-cell neoplasm and ∼2% to 9% patients develop an aggressive lymphoma, most commonly diffuse large B-cell lymphoma (Richter transformation, DLBCL-RT). Programmed death-1 (PD-1) pathway plays a crucial role in tumor host immunity evasion and its blockade has emerged as an effective anti-cancer immunotherapy. PD-L1 and PD-1 expression has shown predictive value in anti-PD cancer immunotherapy; however, it has not been well documented in CLL/SLL and DLBCL-RT...
May 14, 2018: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29761106/current-strategies-and-future-directions-to-optimize-acl-reconstruction-in-adolescent-patients
#19
Dustin Jon Richter, Roger Lyon, Scott Van Valin, Xue-Cheng Liu
The incidence of anterior cruciate ligament (ACL) injuries in the pediatric population has risen in recent years. These injuries have historically presented a management dilemma in skeletally immature patients with open physes and significant growth remaining at time of injury. While those nearing skeletal maturity may be treated with traditional, transphyseal adult techniques, these same procedures risk iatrogenic damage to the growth plates and resultant growth disturbances in younger patients with open physes...
2018: Frontiers in Surgery
https://www.readbyqxmd.com/read/29761097/commentary-human-liver-flukes
#20
COMMENT
Monica Catarina Botelho, Francisco Almeida, Joachim Richter, Antonio Sarmento
No abstract text is available yet for this article.
2018: Frontiers in Public Health
keyword
keyword
31749
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"