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https://www.readbyqxmd.com/read/29775125/influence-of-tetramethylammonium-hydroxide-tmah-on-the-microbial-properties-of-anaerobic-granular-sludge-acclimated-to-isoplophyl-alcohol-ipa-wastewater-under-psychrophilic-conditions
#1
Tsuyoshi Danshita, Yuma Miyaoka, Norihisa Matsuura, Haruhiko Sumino, Takashi Yamaguchi, Kazuaki Syutsubo
In this study, a continuous flow experiment was conducted in which a lab-scale upflow anaerobic sludge blanket (UASB) reactor at psychrophilic conditions (18-19°C) was fed with artificial wastewater, containing tetramethylammonium hydroxide (TMAH) and isoplophyl alcohol (IPA), from the electronics industry. This was done to evaluate process performance and microbial properties of the granular sludge that was retained in the reactor. The inoculated granular sludge was precultured with IPA containing wastewater but not TMAH; as a result, no degradation was observed in 30 days of operation...
May 18, 2018: Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
https://www.readbyqxmd.com/read/29774802/the-notion-of-manhood-embedment-in-the-practice-of-traditional-male-circumcision-in-ngove-village-limpopo-south-africa
#2
Tryphosa Siweya, Tholene Sodi, Mbuyiselo Douglas
Traditional male circumcision (TMC) is a cultural ritual that involves the removal of the penile foreskin of a male person undertaken as part of a rite of passage from childhood into adulthood. The aim of the study was to determine the notions of manhood in TMC by African adolescent boys in Ngove Village, Limpopo Province. This was a qualitative study that sampled a total of 20 adolescent boys through purposive sampling. Data were collected using semistructured interviews and analyzed through interpretive phenomenological analysis (IPA)...
May 1, 2018: American Journal of Men's Health
https://www.readbyqxmd.com/read/29766519/lack-of-correspondence-between-the-reactive-proactive-questionnaire-and-the-impulsive-premeditated-aggression-scale-among-forensic-psychiatric-outpatients
#3
Danique Smeijers, Suzanne Brugman, Katinka von Borries, Robbert-Jan Verkes, Erik Bulten
The most studied bimodal classifications of aggressive behavior are the impulsive/premeditated distinction measured with the Impulsive Premeditated Aggression Scale and the reactive/proactive distinction measured with the Reactive Proactive Questionnaire. The terms of these classifications are often used interchangeably, assuming that reactive aggression is equivalent to impulsive aggression and that proactive aggressive behavior is the same as premeditated aggression. The correspondence or discrepancy between both aggression classifications/questionnaires, however, is understudied...
May 15, 2018: Aggressive Behavior
https://www.readbyqxmd.com/read/29764370/-tuberculosis-in-advanced-hiv-infection-is-associated-with-increased-expression-of-ifn%C3%AE-and-its-downstream-targets
#4
Sheetal Verma, Peicheng Du, Damalie Nakanjako, Sabine Hermans, Jessica Briggs, Lydia Nakiyingi, Jerrold J Ellner, Yukari C Manabe, Padmini Salgame
BACKGROUND: Tuberculosis (TB) is the major cause of death in Human Immunodeficiency Virus (HIV)-infected individuals. However, diagnosis of TB in HIV remains challenging particularly when HIV infection is advanced. Several gene signatures and serum protein biomarkers have been identified that distinguish active TB from latent infection. Our study was designed to assess if gene expression signatures and cytokine levels would distinguish active TB in advanced HIV. METHODS: We conducted a case-control study of whole blood RNA-Seq and plasma cytokine/chemokine analysis in HIV-infected with CD4+ T cell count of ≤ 100 cells/μl, with and without active TB...
May 15, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29762736/comparative-transcriptome-analysis-of-rumen-papillae-in-suckling-and-weaned-japanese-black-calves-using-rna-sequencing
#5
Koki Nishihara, Daichi Kato, Yutaka Suzuki, Dahye Kim, Misato Nakano, Yu Yajima, Satoshi Haga, Miwa Nakano, Hiroshi Ishizaki, Ryouka Kawahara-Miki, Tomohiro Kono, Kazuo Katoh, Sang-Gun Roh
The length and density of rumen papillae starts to increase during weaning and growth of ruminants. This significant development increases the intraruminal surface area and the efficiency of VFA (acetate, propionate, butyrate, etc.) uptake. Thus, it is important to investigate the factors controlling the growth and development of rumen papillae during weaning. This study aimed to compare the transcriptomes of rumen papillae in suckling and weaned calves. Total RNA was extracted from the rumen papillae of 10 male Japanese Black calves (5 suckling calves, 5 wk old; 5 weaned calves, 15 wk old) and used in RNA-sequencing...
May 12, 2018: Journal of Animal Science
https://www.readbyqxmd.com/read/29762474/saccharomyces-cerevisiae-boulardii-reduces-the-deoxynivalenol-induced-alteration-of-the-intestinal-transcriptome
#6
Imourana Alassane-Kpembi, Philippe Pinton, Jean-François Hupé, Manon Neves, Yannick Lippi, Sylvie Combes, Mathieu Castex, Isabelle P Oswald
Type B trichothecene mycotoxin deoxynivalenol (DON) is one of the most frequently occurring food contaminants. By inducing trans-activation of a number of pro-inflammatory cytokines and increasing the stability of their mRNA, trichothecene can impair intestinal health. Several yeast products, especially Saccharomyces cerevisiae , have the potential for improving the enteric health of piglets, but little is known about the mechanisms by which the administration of yeast counteracts the DON-induced intestinal alterations...
May 15, 2018: Toxins
https://www.readbyqxmd.com/read/29762016/rapid-2-ms-interrogation-of-electrochemical-aptamer-based-sensor-response-using-intermittent-pulse-amperometry
#7
Mirelis Santos-Cancel, Robert Alexander Lazenby, Ryan J White
In this manuscript, we employ the technique intermittent pulse amperometry (IPA) to interrogate equilibrium and kinetic target binding to the surface of electrochemical, aptamer-based (E-AB) sensors, achieving as fast as 2 ms time resolution. E-AB sensors comprise an electrode surface modified with a flexible nucleic acid aptamer tethered at the 3'-terminus with a redox-active molecule. The introduction of a target changes the conformation and flexibility of the nucleic acid which alters the charge transfer rate of the appended redox molecule...
May 15, 2018: ACS Sensors
https://www.readbyqxmd.com/read/29760811/global-dna-methylation-changes-spanning-puberty-are-near-predicted-estrogen-responsive-genes-and-enriched-for-genes-involved-in-endocrine-and-immune-processes
#8
Emma E Thompson, Jessie Nicodemus-Johnson, Kyung Won Kim, James E Gern, Daniel J Jackson, Robert F Lemanske, Carole Ober
Background: The changes that occur during puberty have been implicated in susceptibility to a wide range of diseases later in life, many of which are characterized by sex-specific differences in prevalence. Both genetic and environmental factors have been associated with the onset or delay of puberty, and recent evidence has suggested a role for epigenetic changes in the initiation of puberty as well. Objective: To identify global DNA methylation changes that arise across the window of puberty in girls and boys...
2018: Clinical Epigenetics
https://www.readbyqxmd.com/read/29760336/enhanced-physical-stability-of-mixed-ion-pair-amphiphile-double-chained-cationic-surfactant-vesicles-in-the-presence-of-cholesterol
#9
An-Tsung Kuo, Cheng-Lin Tu, Yu-Min Yang, Chien-Hsiang Chang
In this study, a pseudodouble-chained ion pair amphiphile (IPA), hexadecyltrimethylammonium-dodecylsulfate (HTMA-DS), and dialkyldimethylammonium bromide (DXDAB) with different chain lengths were used as the main materials to fabricate positively charged catanionic vesicles with various mole fractions of cholesterol. The effects of cholesterol and DXDAB alkyl chain length on physical stability of the catanionic vesicles were then investigated by size, zeta potential, and Fourier transform infrared analyses...
May 15, 2018: Journal of Oleo Science
https://www.readbyqxmd.com/read/29760132/a-multimodal-imaging-approach-enables-in-vivo-assessment-of-antifungal-treatment-in-a-mouse-model-of-invasive-pulmonary-aspergillosis
#10
Jennifer Poelmans, Uwe Himmelreich, Liesbeth Vanherp, Luca Zhai, Amy Hillen, Bryan Holvoet, Sarah Belderbos, Matthias Brock, Johan Maertens, Greetje Vande Velde, Katrien Lagrou
Aspergillus fumigatus causes life-threatening lung infections in immunocompromised patients. Mouse models are extensively used in research to assess the in vivo efficacy of antifungals. In recent years, there has been an increasing interest in the use of non-invasive imaging techniques to evaluate experimental infections. However, single imaging modalities have limitations concerning the type of information they can provide. In this study, magnetic resonance imaging and bioluminescence imaging were combined to obtain longitudinal information on the extent of developing lesions and fungal load in a leucopenic mouse model of IPA...
May 14, 2018: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/29756775/heterogeneous-interaction-of-various-natural-dust-samples-with-isopropanol-as-a-probe-voc
#11
Mohamad Nour Zeineddine, Manolis N Romanias, Véronique Riffault, Frederic Thevenet
The adsorption properties of mineral dust toward organic molecules are poorly characterized so far. Heterogeneous processes between trace gases and mineral particles can affect the oxidative capacity of the atmosphere as well as constitute additional sources or sinks for these species. The current study investigates the adsorption efficiencies of natural dust samples collected from North and West Africa, Saudi Arabia, and Arizona desert regions toward isopropanol (IPA), a common organic pollutant released in significant amounts in the atmosphere, and used here as a probe molecule...
May 14, 2018: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/29751120/evaluation-of-a-risk-guided-strategy-for-empiric-carbapenem-use-in-febrile-neutropenia
#12
Ai Leng Khoo, Ying Jiao Zhao, Monica Teng, Ding Ying, Jing Jin, Yen Lin Chee, Li Mei Poon, Siew Eng Lim, Liang Piu Koh, Wee Joo Chng, Boon Peng Lim, Li Yang Hsu, Louis Yi Ann Chai
Febrile neutropenia (FN) is associated with substantial morbidity and necessitate empiric broad spectrum antibiotic treatment. We evaluated a risk-guided FN management strategy using empiric piperacillin-tazobactam and carbapenem in a prospective cohort study. The analysis involved 723 FN episodes in hospitalised adult patients, including those with severe sepsis or prior infection/colonisation with extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae. Propensity score matching analysis was used to adjust for baseline differences between treatment groups and produced 267 matched pairs...
May 8, 2018: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/29737199/steep-infundibulopelvic-angle-ipa-as-a-new-risk-factor-for-flexible-ureteroscope-damage-and-complicated-postoperative-course
#13
Tomasz Ozimek, Jens Cordes, Judith Riccarda Wiessmeyer, Michael Heribert Schneider, Marie Christine Hupe, Nils Gilbert, Axel Stuart Merseburger, Mario Wolfgang Kramer
OBJECTIVE: The increasing number of flexible ureteroscopy (fURS) procedures, the fragility of devices and their growing repair costs represent a substantial burden for urological departments worldwide. No risk factors of flexible ureteroscope damage have been identified so far. The objective of this study was to investigate the impact of infundibulopelvic angle (IPA) on device damage and on other intra- and postoperative factors such as length of hospital stay (LOS), surgical complications, stone-free rate (SFR), operation and fluoroscopy time...
May 8, 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29737102/-galactomannan-tests-of-bronchoalveolar-lavage-fluid-for-diagnosing-invasive-pulmonary-aspergillosis
#14
Jin Deng, Si-Ying Wu, Ya Liu, Ying Ma, Yi Xie, Zhi-Xing Chen, Zhong-Qiu Dai, Jie-Lun Deng, Mei Kang
OBJECTIVE: To determine the value of galactomannan (GM) in bronchoalveolar lavage fluid (BALF) for diagnosing invasive pulmonary aspergillosis. METHODS: According to the European Organization for Research and Treatment of Cancer / Invasive Fungal Infection Group (EORTC / IFICG) and the American Mycosis Research Group (MSG),and the American College of Infectious Diseases (IDSA) guidelines,295 patients with pulmonary aspergillosis (IPA) and high risk of invasive infections were divided into four groups: IPA group (42 cases),clinically diagnosed group (68 cases),suspected group (61 cases),and non-IPA group (124 cases)...
January 2018: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/29736869/muslim-physicians-and-palliative-care-attitudes-towards-the-use-of-palliative-sedation
#15
George Muishout, Hanneke W M van Laarhoven, Gerard Wiegers, Ulrike Popp-Baier
BACKGROUND: Muslim norms concerning palliative sedation can differ from secular and non-Muslim perceptions. Muslim physicians working in a Western environment are expected to administer palliative sedation when medically indicated. Therefore, they can experience tension between religious and medical norms. OBJECTIVE: To gain insight into the professional experiences of Muslim physicians with palliative sedation in terms of religious and professional norms. DESIGN: Interpretative phenomenological study using semi-structured interviews to take a closer look at the experiences of Muslim physicians with palliative sedation...
May 8, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29733661/trauma-exposure-and-aggression-toward-partners-and-children-contextual-influences-of-fear-and-anger
#16
Amy D Marshall, Michael E Roettger, Alexandra C Mattern, Mark E Feinberg, Damon E Jones
Trauma exposure is a consistent correlate of intimate partner aggression (IPA) and parent-to-child aggression (PCA) perpetration, and difficulties with emotions (particularly fear and anger) are hypothesized to underlie these relations. However, the absence of knowledge of the immediate, contextual influence of emotions on aggression renders existing conclusions tenuous. This study illustrates a new method for studying contextual influences on aggressive behavior. Quarterly for 1 year, 94 men and 109 women with children age 2...
May 7, 2018: Journal of Family Psychology: JFP
https://www.readbyqxmd.com/read/29731289/solvent-effects-on-the-retention-mechanisms-of-an-amylose-based-sorbent
#17
Hung-Wei Tsui, Kai-Tse Cheng, Ang-Yeh Lin, Sin-Chang Chen, Yi-Lun Hung, Ping-Yi Chou
The mobile phase, when used in combination with a polysaccharide-based sorbent, often contains hydrocarbons with polar modifiers. Studies have investigated the effect of solvent on the recognition mechanism of polysaccharide-based sorbents, but it remains unclear how these modifier molecules affect solute retention behavior. This study used an amylose 3,5-dichlorophenylcarbamate-based sorbent to systematically investigate the retention behavior of various solutes as a function of the concentration of four polar modifiers: ethanol, isopropanol, methyl tert-butyl ether, and acetone...
April 27, 2018: Journal of Chromatography. A
https://www.readbyqxmd.com/read/29727961/pyrethroid-insecticide-lambda-cyhalothrin-induces-hepatic-cytochrome-p450-enzymes-oxidative-stress-and-apoptosis-in-rats
#18
María-Aránzazu Martínez, Irma Ares, José-Luis Rodríguez, Marta Martínez, David Roura-Martínez, Victor Castellano, Bernardo Lopez-Torres, María-Rosa Martínez-Larrañaga, Arturo Anadón
This study aimed to examine in rats the effects of the Type II pyrethroid lambda-cyhalothrin on hepatic microsomal cytochrome P450 (CYP) isoform activities, oxidative stress markers, gene expression of proinflammatory, oxidative stress and apoptosis mediators, and CYP isoform gene expression and metabolism phase I enzyme PCR array analysis. Lambda-cyhalothrin, at oral doses of 1, 2, 4 and 8mg/kg bw for 6days, increased, in a dose-dependent manner, hepatic activities of ethoxyresorufin O-deethylase (CYP1A1), methoxyresorufin O-demethylase (CYP1A2), pentoxyresorufin O-depentylase (CYP2B1/2), testosterone 7α- (CYP2A1), 16β- (CYP2B1), and 6β-hydroxylase (CYP3A1/2), and lauric acid 11- and 12-hydroxylase (CYP4A1/2)...
August 1, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29721051/lncrna-pcat1-and-its-genetic-variant-rs1902432-are-associated-with-prostate-cancer-risk
#19
Qinbo Yuan, Haiyan Chu, Yuqiu Ge, Gaoxiang Ma, Mulong Du, Meilin Wang, Zhengdong Zhang, Wei Zhang
Emerging evidence has showed that lncRNAs and trait-associated loci in lncRNAs play a crucial role in the progression of cancer including prostate cancer (PCa).This study aimed to investigate the molecular mechanisms of lncRNA PCAT1 involved in PCa development and its genetic variant associated with PCa risk. We applied cell proliferation and apoptosis assays to assess the effect of PCAT1 on PCa cell phenotypes. In addition, the genome-wide profiling of gene expression was assessed from three pairs of DU145 cells transfected with PCAT1 overexpression vector or negative control (NC) vector...
2018: Journal of Cancer
https://www.readbyqxmd.com/read/29719546/metabolome-integrated-analysis-of-high-temperature-response-in-pinus-radiata
#20
Mónica Escandón, Mónica Meijón, Luis Valledor, Jesús Pascual, Gloria Pinto, María Jesús Cañal
The integrative omics approach is crucial to identify the molecular mechanisms underlying high-temperature response in non-model species. Based on future scenarios of heat increase, Pinus radiata plants were exposed to a temperature of 40°C for a period of 5 days, including recovered plants (30 days after last exposure to 40°C) in the analysis. The analysis of the metabolome using complementary mass spectrometry techniques (GC-MS and LC-Orbitrap-MS) allowed the reliable quantification of 2,287 metabolites...
2018: Frontiers in Plant Science
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