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https://www.readbyqxmd.com/read/29222992/inflammatory-chemokine-eotaxin-1-is-correlated-with-age-in-heroin-dependent-patients-under-methadone-maintenance-therapy
#1
Hsiang-Wei Kuo, Tung-Hsia Liu, Hsiao-Hui Tsou, Ya-Ting Hsu, Sheng-Chang Wang, Chiu-Ping Fang, Chia-Chen Liu, Andrew C H Chen, Yu-Li Liu
BACKGROUND: Degeneration of central neurons and fibers has been observed in postmortem brains of heroin dependent patients. However, there are no biomarkers to predict the severity of neurodegeneration related to heroin dependence. A correlation has been reported between inflammatory C-C motif chemokine ligand 11 (CCL11, or eotaxin-1) and neurodegeneration in Alzheimer's disease. METHODS: Three-hundred-forty-four heroin dependent, Taiwanese patients under methadone maintenance treatment (MMT) were included with clinical assessment and genomics information...
November 28, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29222825/outcome-of-sonography-based-minimally-invasive-surgery-for-deep-infiltrating-endometriosis-of-the-ureter-and-urinary-bladder-a-retrospective-cohort-study
#2
Gernot Hudelist, Ayman Tammaa, Kristine Aas-Eng, Lisa Kirchner, Nadja Fritzer, Zoltan Nemeth, Michael Lamche
INTRODUCTION: To evaluate the accuracy of transvaginal sonography for preoperative detection of bladder endometriosis and surgical outcomes regarding fertility and pain symptoms of women with urinary tract endometriosis. MATERIAL AND METHODS: Retrospective cohort study of consecutive patients with urinary tract endometriosis undergoing laparoscopic partial cystectomy and/or ureterolysis/decompression, ureteric resection and end-to-end anastomosis or ureteroneocystostomy for ureteral stenosis and hydronephrosis...
December 8, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29222598/information-needs-of-adolescent-and-young-adult-cancer-patients-and-their-parent-carers
#3
Maria C McCarthy, Robyn McNeil, Sarah Drew, Lisa Orme, Susan M Sawyer
PURPOSE: This study aimed to explore health-related information needs of adolescent and young adults (AYAs) and their parent-carers and to examine demographic and clinical variables associated with unmet information needs, including patient activation. METHODS: In a national cross-sectional study, 196 Australian AYAs diagnosed with cancer between 15 and 25 years and within 24 months of diagnosis and 204 parent-carers reported on total and unmet needs for cancer and health-related information...
December 8, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29221549/-hypnosis-to-fight-against-pain-and-anxiety-in-palliative-care
#4
REVIEW
Didier Quintini, Claire Vitale, Michelle Gaide, Frédérique Surdej, Sébastien Salas
In our society, hypnosis sometimes has a negative, distorted image. For several years now it has become more widespread in the healthcare field and its use has increased in caring for symptoms such as pain and anxiety. It can be of great help in palliative situations.
December 2017: Soins; la Revue de Référence Infirmière
https://www.readbyqxmd.com/read/29221470/potential-diagnostic-markers-of-olanzapine-efficiency-for-acute-psychosis-a-focus-on-peripheral-biogenic-amines
#5
A E Taraskina, R F Nasyrova, A M Zabotina, D N Sosin, К А Sosina, E E Ershov, M N Grunina, E M Krupitsky
BACKGROUND: Biomarkers are now widely used in many fields of medicine, and the identification of biomarkers that predict antipsychotic efficacy and adverse reactions is a growing area of psychiatric research. Monoamine molecules of the peripheral bloodstream are possible prospective biomarkers based on a growing body of evidence indicating that they may reflect specific changes in neurotransmitters in the brain. The aim of this study was to detect peripheral biogenic amine indicators of patients with acute psychosis and to test the correlations between the biological measures studied and the psychopathological status of the patients...
December 8, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/29221467/urothelial-cells-may-indicate-underlying-bacteriuria-in-pregnancy-at-term-a-comparative-study
#6
N Liou, J Currie, C James, J Malone-Lee, A L David
BACKGROUND: Urinary tract infection is common in pregnancy. Urine is sampled from by mid-stream collection (MSU). If epithelial cells are detected, contamination by vulvo-vagial skin and skin bacteria is assumed. Outside pregnancy, catheter specimen urine (CSU) is considered less susceptible to contamination. We compared MSU and CSU methods in term pregnancy to test these assumptions. METHODS: Healthy pregnant women at term gestation (n = 32, median gestation 38 + 6 weeks, IQR 37 + 6-39 + 2) undergoing elective caesarean section provided a MSU and CSU for paired comparison that were each analysed for bacterial growth and bladder distress by fresh microscopy, sediment culture and immunofluorescent staining...
December 8, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29221211/the-prevalence-of-polycystic-ovary-syndrome-in-reproductive-aged-women-of-different-ethnicity-a-systematic-review-and-meta-analysis
#7
Tao Ding, Paul J Hardiman, Irene Petersen, Fang-Fang Wang, Fan Qu, Gianluca Baio
The prevalence of PCOS was investigated in many studies in different continents. However, there is no established prevalence of PCOS for distinct ethnic groups. In the current analysis, we conducted searches in PubMed, The Cochrane Library, EMBASE, CINAHL up to Jan. 2017 to identify studies reporting prevalence of PCOS in the general female population. Forty-two studies were identified, with 13 eligible for evidence synthesis. The prevalence among different ethnicity was estimated using random effect modelling...
November 10, 2017: Oncotarget
https://www.readbyqxmd.com/read/29219856/the-interaction-of-depressive-symptoms-and-hazardous-drinking-in-relation-to-tobacco-craving-among-treatment-seeking-depressed-smokers-sex-differences
#8
Rubén Rodríguez-Cano, Ana López-Durán, Daniel J Paulus, Carmela Martínez-Vispo, Elena Fernández Del Río, Elisardo Becoña, Michael J Zvolensky
OBJECTIVES: The present study sought to address whether there is sex effect in the interactive effect between depressive symptoms and hazardous drinking in the prediction of smoking craving after cognitive-behavioral smoking cessation treatment among those with at least mild depression. METHODS: Participants (n = 114, mean age 42.0, SD = 9.73, 64% women) were treatment-seeking smokers who attended 6 weekly 1-hour sessions involving psychological treatment for cessation...
December 6, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/29218658/hypopharyngeal-multichannel-intraluminal-impedance-leads-to-the-promising-outcome-of-antireflux-surgery-in-japanese-population-with-laryngopharyngeal-reflux-symptoms
#9
Takeshi Suzuki, Yosuke Seki, Yoshitaka Okamoto, Toshitaka Hoppo
BACKGROUND: Clinical characteristics of laryngopharyngeal reflux (LPR) in Japanese population remain unclear, and its treatment outcome is suboptimal. The objectives of this study were to evaluate Japanese patients with LPR symptoms using hypopharyngeal multichannel intraluminal impedance (HMII) and to assess the outcome of antireflux surgery (ARS). METHODS: Subjects included patients who had LPR symptoms for > 12 weeks or laryngoscopic findings suggestive of LPR and underwent laryngoscopy and esophageal testing including HMII...
December 7, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29217444/outcome-and-complications-using-negative-pressure-wound-therapy-in-the-groin-for-perivascular-surgical-site-infections-after-vascular-surgery
#10
Sebastian Andersson, Christina Monsen, Stefan Acosta
AIM OF THE STUDY: The aim of this study was to investigate graft preservation, major bleeding and reinfection rate using negative pressure wound therapy (NPWT) for perivascular surgical site infections (SSI) in the groin after vascular surgery, and factors associated with failure of treatment. MATERIALS AND METHODS: Retrospective data 2004-2015. Failure of wound treatment was defined as a wound not healed within four months, visible graft material or native artery after one month, bleeding from the wound leading to discontinuation of treatment, or death or amputation due to the groin infection...
December 4, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29217362/rethinking-prehospital-stroke-notification-assessing-utility-of-emergency-medical-services-impression-and-cincinnati-prehospital-stroke-scale
#11
Stephen W English, Alejandro A Rabinstein, Jay Mandrekar, James P Klaas
BACKGROUND AND PURPOSE: Although prehospital stroke notification has improved stroke treatment, incorporation of these systems into existing infrastructure has resulted in new challenges. The goal of our study was to design an effective prehospital notification system that allows for early and accurate identification of patients presenting with acute stroke. METHODS: We conducted a retrospective single-center cohort study of patients presenting with suspicion of acute stroke from 2014 to 2015...
December 5, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/29217321/bronchoscopy-as-a-screening-tool-for-symptomatic-tracheomalacia-in-oesophageal-atresia
#12
Hemanshoo Thakkar, Manasvi Upadhyaya, Iain E Yardley
AIM: Oesophagealatresia/tracheo-oesophageal fistula (OA-TOF) is associated with tracheomalacia (TM). In our institution it is routine for OA-TOF patients to undergo dynamic flexible bronchoscopy (DFB) assessing both the site of the fistula and the presence or absence of TM. We aimed to determine the value of this investigation as a screening tool to predict subsequent symptomatic tracheomalacia in these patients. METHODS: All patients with OA-TOF who underwent DFB at the time of initial repair between June 2014 and November 2016 were included prospectively...
November 11, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29217297/defects-in-bioenergetic-coupling-in-schizophrenia
#13
REVIEW
Courtney R Sullivan, Sinead M O'Donovan, Robert E McCullumsmith, Amy Ramsey
Synaptic neurotransmission relies on maintenance of the synapse and meeting the energy demands of neurons. Defects in excitatory and inhibitory synapses have been implicated in schizophrenia, likely contributing to positive and negative symptoms as well as impaired cognition. Recently, accumulating evidence has suggested that bioenergetic systems, important in both synaptic function and cognition, are abnormal in psychiatric illnesses such as schizophrenia. Animal models of synaptic dysfunction demonstrated endophenotypes of schizophrenia as well as bioenergetic abnormalities...
October 24, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/29217290/growth-patterns-in-early-juvenile-idiopathic-arthritis-results-from-the-childhood-arthritis-prospective-study-caps
#14
Flora McErlane, Roberto Carrasco, Lianne Kearsley-Fleet, Eileen M Baildam, Lucy R Wedderburn, Helen E Foster, Yiannis Ioannou, S E Alice Chieng, Joyce E Davidson, Wendy Thomson, Kimme L Hyrich
OBJECTIVES: To investigate early vertical growth patterns and factors associated with poor growth in a modern inception cohort of UK children with juvenile idiopathic arthritis (JIA) using data from the Childhood Arthritis Prospective Study (CAPS). METHODS: A study period of 3 years was chosen. Children included in this analysis had a physician diagnosis of JIA and had height measurements available at both baseline and at 3-years of follow-up. Height is presented as z-scores calculated using World Health Organisation growth standards for age and gender...
November 7, 2017: Seminars in Arthritis and Rheumatism
https://www.readbyqxmd.com/read/29216845/a-comparison-of-the-test-negative-and-the-traditional-case-control-study-designs-for-estimation-of-influenza-vaccine-effectiveness-under-nonrandom-vaccination
#15
Meng Shi, Qian An, Kylie E C Ainslie, Michael Haber, Walter A Orenstein
BACKGROUND: As annual influenza vaccination is recommended for all U.S. persons aged 6 months or older, it is unethical to conduct randomized clinical trials to estimate influenza vaccine effectiveness (VE). Observational studies are being increasingly used to estimate VE. We developed a probability model for comparing the bias and the precision of VE estimates from two case-control designs: the traditional case-control (TCC) design and the test-negative (TN) design. In both study designs, acute respiratory illness (ARI) patients seeking medical care testing positive for influenza infection are considered cases...
December 8, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29216768/a-mysterious-case-of-complex-regional-pain-syndrome-in-a-9-year-old-girl
#16
Angela Burian, Othmar Schuhfried, Richard Crevenna
PURPOSE: To describe the clinical manifestation and the treatment of complex regional pain syndrome type II in childhood. METHODS: Using information on the symptoms, diagnosis, rehabilitation and outcome of a young patient with complex regional pain syndrome type II. RESULTS: A 9-year -old girl had severe pain in the region of the left foot, signs of a common fibular nerve entrapment, hyperalgesia not limited to the distribution of the injured nerve, weakness and temperature asymmetry unknown origin...
December 7, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29216633/greater-experience-of-negative-non-target-emotions-by-patients-with-neurodegenerative-diseases-is-related-to-lower-emotional-well-being-in-caregivers
#17
Kuan-Hua Chen, Jenna L Wells, Marcela C Otero, Sandy J Lwi, Claudia M Haase, Robert W Levenson
BACKGROUND: Behavioral symptoms in patients with neurodegenerative diseases can be particularly challenging for caregivers. Previously, we reported that patients with frontotemporal dementia (FTD) and Alzheimer's disease (AD) experienced emotions that were atypical or incongruent with a given situation (i.e., non-target emotions). AIM: We tested the hypothesis that greater experience of non-target emotions by patients is associated with lower caregiver emotional well-being...
December 8, 2017: Dementia and Geriatric Cognitive Disorders
https://www.readbyqxmd.com/read/29215188/pcr-test-in-induced-sputum-of-patients-with-pulmonary-tuberculosis
#18
Verônica da Silva Paiva, Fernanda Luiza Staub, Dirceu Felipe Valentini, Regina Bones Barcellos, Karen Barros Schmid, Elis Regina Dalla Costa, Maria Lucia Rosa Rossetti, Paulo de Tarso Roth Dalcin, Denise Rossato Silva
INTRODUCTION: Induced sputum (IS) is an alternative method of obtaining sputum, but IS smears are frequently negative. Culture is more time-consuming in its results, and less useful to guide the diagnosis. Polymerase chain reaction (PCR) is the most common methodology for rapid diagnosis of TB, and few studies evaluated its role in IS samples. OBJECTIVES: The objective of this study is to determine the diagnostic yield of PCR for TB compared with culture in IS samples...
December 7, 2017: Clinical Respiratory Journal
https://www.readbyqxmd.com/read/29215162/delineating-the-association-between-mode-of-delivery-and-postpartum-depression-symptoms-a-longitudinal-study
#19
Patricia Eckerdal, Marios K Georgakis, Natasa Kollia, Anna-Karin Wikström, Ulf Högberg, Alkistis Skalkidou
INTRODUCTION: Although a number of perinatal factors have been implied in the etiology of postpartum depression (PPD), the role of mode of delivery remains controversial. Our aim was to explore the association between mode of delivery and PPD, considering the potentially mediating or confounding role of several covariates MATERIAL AND METHODS: In a longitudinal-cohort study in Uppsala, Sweden, with 3888 unique pregnancies followed-up postpartum, the effect of mode of delivery (spontaneous vaginal delivery, vacuum extraction, elective cesarean section, emergency cesarean section) on self-reported PPD symptoms (Edinburgh Postnatal Depression Scale ≥12) at six weeks postpartum was investigated through logistic regression models and path analysis RESULTS: The overall prevalence of PPD was 13%...
December 7, 2017: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/29215132/may-car-washing-represent-a-risk-for-legionella-infection
#20
T Baldovin, A Pierobon, C Bertoncello, E Destefani, M Gennari, A Stano, V Baldo
BACKGROUND: Legionella is a ubiquitous Gram-negative bacterium naturally found in aquatic environments. It can pose a health problem when it grows and spreads in man-made water systems. Legionella pneumophila is the most common cause of Legionnaires' disease nowadays, a community-acquired pneumonia with pulmonary symptoms and chest radiography no different from any other form of infectious pneumonia. Legionella monitoring is important for public health reasons, including the identification of unusual environmental sources of Legionella...
January 2018: Annali di Igiene: Medicina Preventiva e di Comunità
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