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https://www.readbyqxmd.com/read/29200569/misidentification-of-wilson-disease-as-schizophrenia-1998-2013-case-report-and-review
#1
Forouzan Elyasi
Wilson's disease (WD) is a neurodegenerative disorder due to copper metabolism. Schizophrenia-like psychosis and delusional disorder are rare forms of psychiatric manifestations of WD. The lack of recognition of these signs and symptoms as being attributable to WD often leads to delays in diagnosis and management. Knowledge about relationship of the psychiatric manifestations to WD can help with the administration of adequate management aimed at both the psychiatric issues and underlying WD. The objectives of this article are to review case reports whose subject is the incorrect diagnosis of schizophrenia or schizophrenia-like syndrome in patients with WD and to detail one case of this mismanagement of the disease...
September 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/29195803/-validation-of-the-french-version-of-the-self-evaluation-of-negative-symptoms-sns
#2
C Hervochon, V Bourgeois, M Rotharmel, J-B Duboc, B Le Goff, P Quesada, D Campion, S Dollfus, O Guillin
INTRODUCTION: Schizophrenia is a disorder affecting 1% of the population and is associated with severe functional impairment. Negative symptoms are responsible for the majority of this impairment, and many patients with schizophrenia have negative symptoms. However, their evaluation is still a challenge. Thus, standardized assessments are needed to facilitate identification of these symptoms. Many tools have been developed, but most are based on observer ratings. Self-evaluation can provide an additional outcome measure and allow patients to be more engaged in their treatment...
November 28, 2017: L'Encéphale
https://www.readbyqxmd.com/read/29188734/psychiatric-axis-i-and-personality-axis-ii-disorders-and-subjective-psychiatric-symptoms-in-chronic-tinnitus
#3
Hanna Sahlsten, Tero Taiminen, Max Karukivi, Noora Sjösten, Johanna Nikkilä, Juuso Virtanen, Janika Paavola, Juho Joutsa, Katri Niinivirta-Joutsa, Mari Takala, Anu Holm, Esa Rauhala, Eliisa Löyttyniemi, Reijo Johansson, Satu K Jääskeläinen
OBJECTIVE: Chronic tinnitus has been associated with several psychiatric disorders. Only few studies have investigated these disorders using validated diagnostic interviews. The aims were to diagnose psychiatric and personality disorders with structured interviews, to assess self-rated psychiatric symptoms and elucidate temporal relations between psychiatric disorders and tinnitus. DESIGN: Current and lifetime DSM-IV diagnoses of axis-I (psychiatric disorders) and axis-II (personality disorders) were assessed using structured clinical interviews (SCID-I and -II)...
November 30, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/29187730/genome-wide-analysis-in-uk-biobank-identifies-four-loci-associated-with-mood-instability-and-genetic-correlation-with-major-depressive-disorder-anxiety-disorder-and-schizophrenia
#4
Joey Ward, Rona J Strawbridge, Mark E S Bailey, Nicholas Graham, Amy Ferguson, Donald M Lyall, Breda Cullen, Laura M Pidgeon, Jonathan Cavanagh, Daniel F Mackay, Jill P Pell, Michael O'Donovan, Valentina Escott-Price, Daniel J Smith
Mood instability is a core clinical feature of affective and psychotic disorders. In keeping with the Research Domain Criteria approach, it may be a useful construct for identifying biology that cuts across psychiatric categories. We aimed to investigate the biological validity of a simple measure of mood instability and evaluate its genetic relationship with several psychiatric disorders, including major depressive disorder (MDD), bipolar disorder (BD), schizophrenia, attention deficit hyperactivity disorder (ADHD), anxiety disorder and post-traumatic stress disorder (PTSD)...
November 30, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/29178463/psychotic-delusional-depression-and-suicidal-attempts-a-systematic-review-and-meta-analysis
#5
R Gournellis, K Tournikioti, G Touloumi, C Thomadakis, P G Michalopoulou, C Christodoulou, A Papadopoulou, A Douzenis
OBJECTIVE: It still remains unclear whether psychotic features increase the risk of suicidal attempts in major depressive disorder. Thus, we attempted, through a systematic review coupled with a meta-analysis, to elucidate further whether unipolar psychotic depression (PMD) compared to non-PMD presents higher levels of suicidal attempts. METHOD: A systematic search was conducted in PubMed, EMBASE, PsycINFO as well as in various databases of the so-called gray literature for all studies providing data on suicidal attempts in PMD compared to non-PMD, and the results were then subjected to meta-analysis...
November 26, 2017: Acta Psychiatrica Scandinavica
https://www.readbyqxmd.com/read/29164439/brief-report-major-depressive-disorder-with-psychotic-features-in-williams-syndrome-a-case-series
#6
Francisca Valdes, Christopher J Keary, Jennifer E Mullett, Michelle L Palumbo, Jessica L Waxler, Barbara R Pober, Christopher J McDougle
Descriptions of individuals with Williams syndrome (WS) and co-morbid major depressive disorder (MDD) with psychotic features have not appeared in the literature. In addition to reviewing previous reports of psychotic symptoms in persons with WS, this paper introduces clinical histories and therapeutic management strategies for three previously unreported adults with WS diagnosed with co-morbid MDD with psychotic features. Co-morbid medical disorders common in WS are highlighted with regard to safe and appropriate pharmacological treatment...
November 21, 2017: Journal of Autism and Developmental Disorders
https://www.readbyqxmd.com/read/29153629/elevated-fingernail-cortisol-levels-in-major-depressive-episodes
#7
Andres Herane-Vives, Susanne Fischer, Valeria de Angel, Toby Wise, Eric Cheung, Kia-Chong Chua, Danilo Arnone, Allan H Young, Anthony J Cleare
BACKGROUND: The extent to which cortisol levels are elevated in major depressive episodes (MDE), and hence could act as a biomarker of illness, remains unclear. Although patient characteristics may explain some of this variation - for example elevated cortisol being more often found in patients with severe, psychotic or melancholic depression - problems with the methods used to measure cortisol may also have contributed to the inconsistent findings. Fingernails are a novel sample that can be used to assess aggregate cortisol concentrations over a 15-day period, and may provide a more accurate reflection of longer term cortisol level changes in MDE and help clarify this issue...
November 7, 2017: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/29125969/psychiatric-comorbidities-and-suicidality-among-patients-with-neuromyelitis-optica-spectrum-disorders-in-argentina
#8
V C Fernández, N Alonso, L Melamud, A M Villa
BACKGROUND: Neuromyelitis optica is a relapsing inflammatory, secondarily demyelinating astrocytopathy that most commonly affects the optic nerves and the spinal cord. OBJECTIVE: This study aimed to evaluate the psychopathological profile, presence of current depression, and suicidality in patients with neuromyelitis optica spectrum disorders (NMOSD) in an Argentinean cohort, and compare these parameters to those in patients with multiple sclerosis (MS) and in healthy controls (HCs)...
November 7, 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/29124951/the-role-of-serious-mental-illness-in-motivation-participation-and-adoption-of-health-behavior-change-among-obese-sedentary-latino-adults
#9
Daniel E Jimenez, Lauren Thomas, Stephen J Bartels
OBJECTIVE: Serious mental illness (SMI; e.g. schizophrenia, schizoaffective disorder, delusional disorder, bipolar disorder, severe major depressive disorder, and psychotic disorders) and Latino ethnicity can produce a compounded health disparity, placing individuals at particularly high risk for excess morbidity and premature mortality. In this study we sought to identify the role of SMI in motivation, participation, and adoption of health behavior change among overweight Latino adults...
November 10, 2017: Ethnicity & Health
https://www.readbyqxmd.com/read/29122405/theory-of-mind-impairment-and-its-clinical-correlates-in-patients-with-schizophrenia-major-depressive-disorder-and-bipolar-disorder
#10
Yan-Yu Wang, Yi Wang, Ying-Min Zou, Ke Ni, Xue Tian, Hong-Wei Sun, Simon S Y Lui, Eric F C Cheung, John Suckling, Raymond C K Chan
BACKGROUND: Although Theory of Mind (ToM) impairment has been observed in patients with a wide range of mental disorders, the similarity and uniqueness of these deficits across diagnostic groups has not been thoroughly investigated. METHODS: We recruited 35 participants with schizophrenia (SCZ), 35 with bipolar disorder (BD), 35 with major depressive disorder (MDD), and 35 healthy controls in this study. All participants were matched in age, gender proportion and IQ estimates...
November 6, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/29068794/results-from-a-drug-utilization-study-of-extended-release-quetiapine-fumarate-prescribed-by-psychiatrists-as-treatment-for-major-depressive-disorder-in-selected-countries-in-the-european-union
#11
Robert S Brody, Charles L Liss, Heather Wray, Kari Kastango, Allison Bryant, Alban Fabre, Anneli Thuresson
This multicenter, observational drug utilization (DU) study (NCT01594996) investigated the profile of patients and specialist providers who prescribed extended release quetiapine fumarate (quetiapine XR) for treatment of major depressive disorder (MDD) across five European countries (Germany, Italy, Romania, Spain, and Sweden). A DU data abstraction form captured information on the characteristics of physicians, patients, and drugs utilized in the medical management of depressive episodes in MDD, where the therapeutic regimen included quetiapine XR...
October 24, 2017: International Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29017064/negative-social-comparisons-and-psychosis-proneness-in-a-healthy-adolescent-population
#12
F A Cotier, T Toulopoulou
There is growing evidence of an association between negative social comparisons (NSC) and both psychosis, and psychosis proneness. The majority of the work thus far, however, has focused largely on one type of NSC, namely, social rank. Whilst social rank is clearly an important factor, an individual's perception of belonging is likely also of importance; particularly, when considering individuals from collectivistic cultures such as China, where greater emphasis is placed on fitting into the group. There is also limited research investigating what factors may contribute towards the relationship between NSC and psychosis proneness, and to what extent this relationship may be due to common familial factors...
September 1, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28981913/olfactory-functioning-in-first-episode-psychosis
#13
Vidyulata Kamath, Patricia Lasutschinkow, Koko Ishizuka, Akira Sawa
BACKGROUND: Though olfactory deficits are well-documented in schizophrenia, fewer studies have examined olfactory performance profiles across the psychosis spectrum. The current study examined odor identification, discrimination, and detection threshold performance in first-episode psychosis (FEP) patients diagnosed with schizophrenia, schizoaffective disorder, bipolar disorder with psychotic features, major depression with psychotic features, and other psychotic conditions. METHOD: FEP patients (n = 97) and healthy adults (n = 98) completed birhinal assessments of odor identification, discrimination, and detection threshold sensitivity for lyral and citralva...
August 31, 2017: Schizophrenia Bulletin
https://www.readbyqxmd.com/read/28966902/mental-health-in-allergic-rhinitis-depression-and-suicidal-behavior
#14
Ameya U Amritwar, Christopher A Lowry, Lisa A Brenner, Andrew J Hoisington, Robert Hamilton, John W Stiller, Teodor T Postolache
A high proportion of suicides visit their medical provider in the month prior to death, but depression, suicidal thoughts, and substance use are seldom addressed. For the clinicians routinely treating a substantial patient population with allergic diseases, there are additional concerns, as allergy has been linked with both depression and suicidal behavior. While psychotropic medications may affect diagnosis of allergies, medications used to treat allergies impact mood and behavior. Thus, we present an overview of the overlap of allergic rhinitis with depression and suicidal behavior in adults, based on clinical and epidemiological data, and our research and clinical experience...
March 2017: Current Treatment Options in Allergy
https://www.readbyqxmd.com/read/28963866/a-study-in-the-general-population-about-sadness-to-disentangle-the-continuum-from-well-being-to-depressive-disorders
#15
Sarah Tebeka, Baptiste Pignon, Ali Amad, Yann Le Strat, Clara Brichant-Petitjean, Pierre Thomas, Guillaume Vaiva, Jean-Luc Roelandt, Imane Benradia, Bruno Etain, Benjamin Rolland, Caroline Dubertret, Pierre A Geoffroy
OBJECTIVE: Sadness is both a common experience in general population and one of the main criteria of major depressive disorder (MDD). We tested the hypothesis of a depressive continuum using sadness as an intermediate experience between well-being and disorder. METHODS: A French cross-sectional Mental Health survey in General Population interviewed 38,694 individuals. We examined prevalences and compared sociodemographic correlates and psychiatric disorders of individuals in 3 independent groups 1) MDD, 2) sadness without MDD, and 3) controls...
January 15, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28959115/semiparametric-regression-analysis-of-repeated-current-status-data
#16
Baosheng Liang, Xingwei Tong, Donglin Zeng, Yuanjia Wang
In many clinical studies, patients may be asked to report their medication adherence, presence of side effects, substance use, and hospitalization information during the study period. However, the exact occurrence time of these recurrent events may not be available due to privacy protection, recall difficulty, or incomplete medical records. Instead, the only available information is whether the events of interest have occurred during the past period. In this paper, we call these incomplete recurrent events as repeated current status data...
July 2017: Statistica Sinica
https://www.readbyqxmd.com/read/28942743/genetic-risk-scores-and-family-history-as-predictors-of-schizophrenia-in-nordic-registers
#17
Y Lu, J G Pouget, O A Andreassen, S Djurovic, T Esko, C M Hultman, A Metspalu, L Milani, T Werge, P F Sullivan
BACKGROUND: Family history is a long-standing and readily obtainable risk factor for schizophrenia (SCZ). Low-cost genotyping technologies have enabled large genetic studies of SCZ, and the results suggest the utility of genetic risk scores (GRS, direct assessments of inherited common variant risk). Few studies have evaluated family history and GRS simultaneously to ask whether one can explain away the other. METHODS: We studied 5959 SCZ cases and 8717 controls from four Nordic countries...
September 25, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28919875/psychological-support-for-young-adults-with-down-syndrome-dohsa-hou-program-for-maladaptive-behaviors-and-internalizing-problems
#18
Haruo Fujino
Psychological and psychiatric dysfunction is a major problem in a substantial proportion of young adults with Down syndrome. Some patients develop psychiatric issues, such as depressive, obsessive-compulsive, or psychotic-like disorders, in their late adolescence or young adulthood. Furthermore, these individuals may experience moderate to severe emotional and psychological distress. Development of a psychosocial treatment to address these issues is needed in addition to psychotropic medication. The current study reports two cases of young adults with Down syndrome, who presented psychiatric symptoms and marked disruption in their daily lives...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28918419/-about-the-association-between-antipsychotic-medication-and-cardiovascular-morbidity-epidemiology-and-possible-background-mechanisms
#19
Gabor Gaszner, Gabor Barna, Peter Dome
The history of antipsychotics began with the discovery of chlorpromazine in the 1950s. Since then this group of medications has become one of the most important element of the armamentarium of psychopharmacology. While initially these pharmacons were used in the treatment of psychotic states (including psychotic mania) in the last approximately 10-15 years new indications - such as treatment of depressive, manic and mixed states and also mood-stabilization in bipolar disorder and also the treatment of major depressive disorder - for several second-generation antipsychotic (SGA) agents have been introduced...
June 2017: Neuropsychopharmacologia Hungarica
https://www.readbyqxmd.com/read/28917190/posttraumatic-stress-symptoms-and-dissociation-between-childhood-trauma-and-two-different-types-of-psychosis-like-experience
#20
Ji Young Choi
This study examined the roles of posttraumatic stress (PTS) symptoms and dissociation in the relationship between childhood trauma and two different types of psychosis-like experience, including persecutory ideation and aberrant experience, in non-psychotic psychiatric patients. From August 2015 to August 2016, among psychiatric out patients seeking treatment at the Department of Psychiatry at a major teaching medical hospital in Seoul, Korea, 169 patients who had never been diagnosed with a psychotic disorder, including schizophrenia spectrum disorder, bipolar disorder, and/or depressive disorder with psychotic features, completed the Korean Childhood Trauma Questionnaire, the Korean version of the Impact of Event Scale-Revised, the modified Korean version of the Peritraumatic Dissociation Experiences Questionnaire, and the Korean Minnesota Multiphasic Personality Inventory-2 (MMPI-2)...
October 2017: Child Abuse & Neglect
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