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https://www.readbyqxmd.com/read/29351687/intraoperative-transpedicular-onyx-injection-to-reduce-vascularity-of-a-thoracic-hemangiopericytoma-after-unsuccessful-preoperative-endovascular-embolization-a-technical-report
#1
Hazem Mashaly, Zoe Zhang, Andrew Shaw, Patrick Youssef, Ehud Mendel
BACKGROUND AND IMPORTANCE: Hemangiopericytoma is a rare vascular tumor with central nervous system involvement representing only 1% of central nervous system tumors. They rarely affect the vertebral column. Complete surgical resection is the treatment of choice for hemangiopericytoma given their high rates of local recurrence. However, the high vascularity of such tumors with the risk of massive bleeding during surgery represents a significant challenge to surgeons. Therefore, preoperative endovascular embolization via the transarterial route has been advocated...
February 1, 2018: Operative Neurosurgery (Hagerstown, Md.)
https://www.readbyqxmd.com/read/29350999/sex-differences-in-abdominal-aortic-aneurysms
#2
Austin Boese, Lin Chang, Ke-Jie Yin, Y Eugene Chen, Jean-Pyo Lee, Milton H Hamblin
Abdominal aortic aneurysm (AAA) is a vascular disorder with a high case fatality rate in the instance of rupture. AAA is a multifactorial disease and the etiology is still not fully understood. AAA is more likely to occur in men, but women have a greater risk of rupture and worse prognosis. Women are reportedly protected against AAA possibly by premenopausal levels of estrogen and are, on average, diagnosed at older ages than men. Here, we review the current body of research on AAA pathophysiology in humans, animal models, and cultured cells, with an emphasis on sex differences and sex steroid hormone signaling...
January 19, 2018: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29350697/antithrombotic-therapy-evaluation-of-the-safety-of-performing-core-needle-biopsy-of-the-breast-without-suspending-medication%C3%A2
#3
Patrice Cameron, Jana Lesko, Marla R London
BACKGROUND: Patients are increasingly presenting for outpatient breast biopsy while taking medically necessary antithrombotic therapy. Cessation of this medication prior to biopsy increases patients' risk of vascular complications. 
. OBJECTIVES: This article evaluates the safety of performing core needle biopsies of the breast in patients without suspending prescription antithrombotic therapy. 
. METHODS: In this retrospective chart review study, patients continued prescription antithrombotic therapy prior to and including the day of biopsy...
February 1, 2018: Clinical Journal of Oncology Nursing
https://www.readbyqxmd.com/read/29350512/electronic-health-record-problem-lists-accurate-enough-for-risk-adjustment
#4
Timothy J Daskivich, Garen Abedi, Sherrie H Kaplan, Douglas Skarecky, Thomas Ahlering, Brennan Spiegel, Mark S Litwin, Sheldon Greenfield
OBJECTIVES: To determine whether comorbidity information derived from electronic health record (EHR) problem lists is accurate. STUDY DESIGN: Retrospective cohort study of 1596 men diagnosed with prostate cancer between 1998 and 2004 at 2 Southern California Veterans Affairs Medical Centers with long-term follow-up. METHODS: We compared EHR problem list-based comorbidity assessment with manual review of EHR free-text notes in terms of sensitivity and specificity for identification of major comorbidities and Charlson Comorbidity Index (CCI) scores...
January 1, 2018: American Journal of Managed Care
https://www.readbyqxmd.com/read/29350493/bleeding-and-thrombotic-complications-of-pediatric-liver-transplant
#5
Alexandra J Borst, Debra L Sudan, Laura A Wang, Michael J Neuss, Jennifer A Rothman, Thomas L Ortel
BACKGROUND: Pediatric patients undergoing liver transplant are at significant risk for bleeding and thrombotic complications due to the complex nature of rebalanced hemostasis in patients with liver disease. METHODS/OBJECTIVES: We reviewed records of 92 pediatric liver and multivisceral transplant cases at Duke University Medical Center between January 2009 and December 2015. The goal was to define the nature and incidence of bleeding and thrombotic complications in this cohort and define potential risk factors...
January 19, 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29350311/shear-wave-elastography-and-afirma%C3%A2-gene-expression-classifier-in-thyroid-nodules-with-indeterminate-cytology-a-comparison-study
#6
Ghobad Azizi, James M Keller, Michelle L Mayo, Kelé Piper, David Puett, Karly M Earp, Carl D Malchoff
PURPOSE: To compare shear wave elastography (SWE) and Afirma™ gene expression classifier (GEC) for diagnosis of malignancy in thyroid nodules (TNs) with Bethesda Classification (BC) III or IV indeterminate cytology. METHODS: This preliminary single-center prospective study was approved by the Institutional Review Board. We evaluated 151 consented patients with 151 indeterminate TNs (123 BC III, 28 BC IV) on fine-needle aspiration biopsy (FNAB). B-mode ultrasound, vascularity, and SWE were performed prior to FNAB...
January 19, 2018: Endocrine
https://www.readbyqxmd.com/read/29350093/thiobarbituric-acid-reactive-substances-relate-to-arterial-stiffness-and-blood-pressure-in-6-to-8-year-old-boys-stratified-by-maternal-risk
#7
Ashleigh Craig, Catharina M C Mels, Ruan Kruger
Early cardiovascular disease (CVD) onset can be inflicted by familial cardiovascular and lifestyle risk factors. We aimed to compare phenotypic characteristics and explore associations between oxidative stress and vascular function in boys stratified by maternal cardiovascular and lifestyle risk. We included 40 Black and 41 White boys (ages 6-8 years), along with the biological mother of each child. The study population was divided into two groups (nonmaternal risk vs. maternal risk) according to maternal risk predetermined by their selfreported cardiovascular and lifestyle risk factors...
January 19, 2018: Free Radical Research
https://www.readbyqxmd.com/read/29349542/laparoscopic-pancreaticoduodenectomy-with-reconstruction-of-the-mesentericoportal-vein-with-the-parietal-peritoneum-and-the-falciform-ligament
#8
Safi Dokmak, Béatrice Aussilhou, Mélanie Calmels, Houcine Maghrebi, Fadhel Samir Ftériche, Olivier Soubrane, Alain Sauvanet
BACKGROUND: With the improvement of the surgical technique of Laparoscopic pancreaticoduodenectomy (LPD), indications will be extended to patients with vascular invasion. With LPD, vascular grafts for reconstruction are more frequently needed because adequate mobilization is not always done and vascular grafts can safely facilitate reconstruction. We describe our experience of reconstruction with the falciform ligament. METHODS: Venous reconstruction is performed after removal of the specimen...
January 18, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29349404/external-jugular-vein-thrombosis-secondary-to-deep-tissue-neck%C3%A2-massage
#9
Sneha Raju, John Byrne
An 85-year-old man presented with an acute asymptomatic lateral neck mass in the context of deep tissue neck massages during the past year. He was referred to vascular surgery after an ultrasound examination of the neck revealed a thrombus in the external jugular vein. His past medical history and comorbidities were noncontributory. A multidisciplinary team of vascular surgeons and hematologists did not recommend any anticoagulation, given that the patient did not have any risk factors for thrombosis as well as normal D-dimer levels...
September 2017: Journal of Vascular Surgery Cases and Innovative Techniques
https://www.readbyqxmd.com/read/29349385/novel-non-gadolinium-enhanced-magnetic-resonance-imaging-technique-of-pedal-artery-aneurysms
#10
J Devin B Watson, Beatrice Grasu, Rajiv Menon, Raymond Pensy, Robert S Crawford, Taehoon Shin
Non-gadolinium-enhanced magnetic resonance angiography (nMRA) is a noninvasive, contrast-free imaging modality used for visualizing pedal arterial anatomy. We report application of the nMRA technique for detailed arterial imaging in a patient with dorsalis pedis aneurysm. Compared with digital subtraction angiography, we demonstrate that nMRA provides sufficient arterial detail needed to develop a complex operative plan before vascular intervention without risk of contrast agent or ionizing radiation exposure...
June 2017: Journal of Vascular Surgery Cases and Innovative Techniques
https://www.readbyqxmd.com/read/29348924/mortality-and-hospitalizations-in-intensive-dialysis-a-systematic-review-and-meta-analysis
#11
Anna Mathew, Jody-Ann McLeggon, Nirav Mehta, Samuel Leung, Valerie Barta, Thomas McGinn, Gihad Nesrallah
Background: Survival and hospitalization are critically important outcomes considered when choosing between intensive hemodialysis (HD), conventional HD, and peritoneal dialysis (PD). However, the comparative effectiveness of these modalities is unclear. Objective: We had the following aims: (1) to compare the association of mortality and hospitalization in patients undergoing intensive HD, compared with conventional HD or PD and (2) to appraise the methodological quality of the supporting evidence...
2018: Canadian Journal of Kidney Health and Disease
https://www.readbyqxmd.com/read/29348394/hoxc6-predicts-invasion-and-poor-survival-in-hepatocellular-carcinoma-by-driving-epithelial-mesenchymal-transition
#12
Pin-Dong Li, Peng Chen, Xin Peng, Charlie Ma, Wen-Jie Zhang, Xiao-Fang Dai
Aberrant expression of HOXC6 has been reported in several malignant tumors, yet little is known about the value of HOXC6 in invasion and prognosis of hepatocellular carcinoma (HCC). HOXC6 expression was positively correlated with high AFP level, liver cirrhosis, larger tumor, vascular invasion and BCLC stage. Kaplan-Meier analysis revealed that HOXC6 was an independent predictor for overall survival (OS) and time to recurrence (TTR). In addition, HOXC6 status could act as prognostic predictor in different risk subgroups...
January 15, 2018: Aging
https://www.readbyqxmd.com/read/29348253/multifunctional-role-of-chymase-in-acute-and-chronic-tissue-injury-and-remodeling
#13
REVIEW
Louis J Dell'Italia, James F Collawn, Carlos M Ferrario
Chymase is the most efficient Ang II (angiotensin II)-forming enzyme in the human body and has been implicated in a wide variety of human diseases that also implicate its many other protease actions. Largely thought to be the product of mast cells, the identification of other cellular sources including cardiac fibroblasts and vascular endothelial cells demonstrates a more widely dispersed production and distribution system in various tissues. Furthermore, newly emerging evidence for its intracellular presence in cardiomyocytes and smooth muscle cells opens an entirely new compartment of chymase-mediated actions that were previously thought to be limited to the extracellular space...
January 19, 2018: Circulation Research
https://www.readbyqxmd.com/read/29348196/placental-findings-and-effect-of-prophylactic-hydrocortisone-in-extremely-preterm-infants
#14
Alice Héneau, Fabien Guimiot, Damir Mohamed, Aline Rideau Batista Novais, Corinne Alberti, Olivier Baud
OBJECTIVES: To investigate the relationship between histologic findings of the placenta and response to early postnatal hydrocortisone treatment used to prevent bronchopulmonary dysplasia (BPD) in extremely preterm infants. METHODS: In an exploratory analysis of the Early Low-Dose Hydrocortisone to Improve Survival Without Bronchopulmonary Dysplasia in Extremely Preterm Infants (PREMILOC) trial, detailed placental analyses were performed on the basis of standardized macroscopic and histologic examinations...
January 18, 2018: Pediatrics
https://www.readbyqxmd.com/read/29348120/apoc3-loss-of-function-mutations-remnant-cholesterol-low-density-lipoprotein-cholesterol-and-cardiovascular-risk-mediation-and-meta-analyses-of-137-895-individuals
#15
Anders B Wulff, Børge G Nordestgaard, Anne Tybjærg-Hansen
OBJECTIVE: Loss-of-function mutations in APOC3 associate with low remnant cholesterol levels and low risk of ischemic vascular disease (IVD). Because some studies show an additional association with low levels of low-density lipoprotein cholesterol (LDL-C), low LDL-C may explain the low risk of IVD in APOC3 loss-of-function heterozygotes. We tested to what extent the low risk of IVD in APOC3 loss-of-function heterozygotes is mediated by low plasma remnant cholesterol and LDL-C. APPROACH AND RESULTS: In APOC3 loss-of-function heterozygotes versus noncarriers, we first determined remnant cholesterol and LDL-C levels in meta-analyses of 137 895 individuals...
January 18, 2018: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/29348119/cigarette-smoke-initiates-oxidative-stress-induced-cellular-phenotypic-modulation-leading-to-cerebral-aneurysm-pathogenesis
#16
Robert M Starke, John W Thompson, Muhammad S Ali, Crissey L Pascale, Alejandra Martinez Lege, Dale Ding, Nohra Chalouhi, David M Hasan, Pascal Jabbour, Gary K Owens, Michal Toborek, Joshua M Hare, Aaron S Dumont
OBJECTIVE: Cigarette smoke exposure (CSE) is a risk factor for cerebral aneurysm (CA) formation, but the molecular mechanisms are unclear. Although CSE is known to contribute to excess reactive oxygen species generation, the role of oxidative stress on vascular smooth muscle cell (VSMC) phenotypic modulation and pathogenesis of CAs is unknown. The goal of this study was to investigate whether CSE activates a NOX (NAPDH oxidase)-dependent pathway leading to VSMC phenotypic modulation and CA formation and rupture...
January 18, 2018: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/29347992/anatomical-relation-between-s1-sacroiliac-screws-entrance-points-and-superior-gluteal-artery
#17
Yong Zhao, Libo You, Wei Lian, Dexin Zou, Shengjie Dong, Tao Sun, Shudong Zhang, Dan Wang, Jingning Li, Wenliang Li, Yuchi Zhao
BACKGROUND: To conduct radiologic anatomical study on the relation between S1 sacroiliac screws' entry points and the route of the pelvic outer superior gluteal artery branches with the aim to provide the anatomical basis and technical reference for the avoidance of damage to the superior gluteal artery during the horizontal sacroiliac screw placement. METHODS: Superior gluteal artery CTA (CT angiography) vascular imaging of 74 healthy adults (37 women and 37 men) was done with 128-slice spiral CT (computed tomography)...
January 18, 2018: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/29347987/determinants-of-long-term-outcome-in-icu-survivors-results-from-the-frog-icu-study
#18
Etienne Gayat, Alain Cariou, Nicolas Deye, Antoine Vieillard-Baron, Samir Jaber, Charles Damoisel, Qin Lu, Xavier Monnet, Isabelle Rennuit, Elie Azoulay, Marc Léone, Heikel Oueslati, Bertrand Guidet, Diane Friedman, Antoine Tesnière, Romain Sonneville, Philippe Montravers, Sébastien Pili-Floury, Jean-Yves Lefrant, Jacques Duranteau, Pierre-François Laterre, Nicolas Brechot, Karine Chevreul, Morgane Michel, Bernard Cholley, Matthieu Legrand, Jean-Marie Launay, Eric Vicaut, Mervyn Singer, Matthieu Resche-Rigon, Alexandre Mebazaa
BACKGROUND: Intensive care unit (ICU) survivors have reduced long-term survival compared to the general population. Identifying parameters at ICU discharge that are associated with poor long-term outcomes may prove useful in targeting an at-risk population. The main objective of the study was to identify clinical and biological determinants of death in the year following ICU discharge. METHODS: FROG-ICU was a prospective, observational, multicenter cohort study of ICU survivors followed 1 year after discharge, including 21 medical, surgical or mixed ICUs in France and Belgium...
January 18, 2018: Critical Care: the Official Journal of the Critical Care Forum
https://www.readbyqxmd.com/read/29346523/timed-up-and-go-test-and-future-dementia-occurrence
#19
Ji Eun Lee, Dong Wook Shin, Su-Min Jeong, Ki Young Son, Belong Cho, Jong Lull Yoon, Byung Joo Park, In Soon Kwon, Jinkook Lee, SangYun Kim
Background: This study evaluated whether baseline results of the Timed Up and Go (TUG) test is associated with future dementia occurrence. Methods: Using the Korean National Health Insurance Service-National Health Screening Cohort database, we identified 49 283 subjects without a dementia diagnosis who participated in the National Screening Program for Transitional Ages at 66 years of age during 2007-2012. Gait impairment was defined as taking longer than 10 seconds to perform the TUG test...
January 16, 2018: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/29346011/minimally-invasive-management-of-severe-aortoiliac-occlusive-disease
#20
Luigi Pascarella, Maen Aboul Hosn
BACKGROUND: Peripheral arterial disease (PAD) is a complex and highly prevalent pathology. It has been estimated that ∼8.5 million people in the United States are affected by PAD, of which 12%-20% are older than age 60. The TransAtlantic Inter-Society Consensus (TASC) guidelines classified aortoiliac atherosclerotic disease based on morphology and level of lesions. TASC II guidelines recommend bilateral surgical bypass to the femoral arteries for TASC II C and D lesions. The aortobifemoral bypass (ABF) has been considered the gold standard in the treatment of aortoiliac occlusive disease (AIOD)...
January 18, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
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