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https://www.readbyqxmd.com/read/28632456/effect-of-carbon-dioxide-laser-on-increasing-vestibular-depth-in-cleft-lip-and-palate-patients
#1
Sogra Yassaei, Hossein Aghili, Alireza Navab Azam, Mahjobeh Gholdani Moghadam, Isa Safari
BACKGROUND: Shallow upper buccal sulcus deformity in cleft lip and palate patients is one of the common secondary deformities after primary cleft lip and palate repair; this deformity may prevent or complicate orthodontic and prosthodontic procedures causing aesthetic and functional problems. A number of methods are described to increase the anterior maxillary sulcus in these patients. PURPOSE: This study assessed the use of a carbon dioxide laser (CO2) to increase the sulcus depth...
June 20, 2017: Photomedicine and Laser Surgery
https://www.readbyqxmd.com/read/28629945/anthropometric-and-aesthetic-outcomes-for-the-nasolabial-region-in-101-consecutive-african-children-with-unilateral-cleft-lip-one-year-after-repair-using-the-anatomical-subunit-approximation-technique
#2
S Mbuyi-Musanzayi, F Tshilombo Katombe, P Lukusa Tshilobo, P Kalenga Mwenze Kayamba, K Devriendt, H Reychler
One hundred and one patients with complete or incomplete cleft lip underwent the anatomical subunit approximation technique for repair. The patients were followed up prospectively for 1year. The objective of this study was to determine the outcomes for the nasolabial area through anthropometric measurements and assessment of the Asher-McDade Aesthetic Index and Steffensen's criteria at 1year after surgery. Six assessors (three cleft surgeons and three non-surgeon medical professionals) examined cropped images; reliability was assessed using Cronbach's alpha...
June 16, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28626108/-a-case-of-partial-deletion-of-the-long-arm-of-chromosome-7
#3
Lin Yang, Ying Cheng, Qian Lin, Hong Zhang
Partial deletion of the long arm of chromosome 7 is a rare disease and is prone to missing the diagnosis or being misdiagnosed. Here we present a case of a 13-year-old boy that showed symptoms such as growth-retardation, moderate intellectual disability, hypotelorism, microcephaly, epicanthal folds, genu varum and lumbar vertebral cleft, but it did not show serious symptoms like cleft lip, urogenital malformation and hypotonia. He was eventually diagnosed as partial deletion of the long arm of chromosome 7 syndrome through gene analysis...
May 28, 2017: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/28615974/presurgical-cleft-lip-and-palate-orthopedics-an-overview
#4
REVIEW
Ibtesam Alzain, Waeil Batwa, Alex Cash, Zuhair A Murshid
Patients with cleft lip and/or palate go through a lifelong journey of multidisciplinary care, starting from before birth and extending until adulthood. Presurgical orthopedic (PSO) treatment is one of the earliest stages of this care plan. In this paper we provide a review of the PSO treatment. This review should help general and specialist dentists to better understand the cleft patient care path and to be able to answer patient queries more efficiently. The objectives of this paper were to review the basic principles of PSO treatment, the various types of techniques used in this therapy, and the protocol followed, and to critically evaluate the advantages and disadvantages of some of these techniques...
2017: Clinical, Cosmetic and Investigational Dentistry
https://www.readbyqxmd.com/read/28607867/a-quadrangular-flap-technique-for-vermilion-repair-in-unilateral-cleft-lip
#5
Hiromu Masuoka
In unilateral cleft lip repair, the vermilion triangular flap technique reported by Noordhoff(1) and its modification are widely accepted for the augmentation of the vermilion height on the medial side of the cleft; however, these techniques do not focus on the deformity of the labial tubercle. In this article, we herein report a modified technique for vermilion repair that is focused on the labial tubercle. The muco-vermilion quadrangular flap was elevated from the lateral lip to augment the labial tubercle...
May 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28605211/profiles-of-vocal-development-in-korean-children-with-and-without-cleft-palate
#6
Seunghee Ha
This study longitudinally investigated vocal development in Korean children from 9 to 18 months of age with and without cleft palate (CP). Utterance samples were collected from 24 children with and without CP at 9, 12, 15 and 18 months of age. Each utterance was categorised into levels of vocalisation using the Korean-translated version of the Stark Assessment of Early Vocal Development-Revised (SAEVD-R). The results showed children with CP produced a significantly higher rate of precanonical vocalisations (the combination of Levels 1, 2, and 3) and a lower rate of Level 4 and 5 vocalisations than children without CP...
June 12, 2017: Clinical Linguistics & Phonetics
https://www.readbyqxmd.com/read/28604778/p63-exerts-spatio-temporal-control-of-palatal-epithelial-cell-fate-to-prevent-cleft-palate
#7
Rose Richardson, Karen Mitchell, Nigel L Hammond, Maria Rosaria Mollo, Evelyn N Kouwenhoven, Niki D Wyatt, Ian J Donaldson, Leo Zeef, Tim Burgis, Rognvald Blance, Simon J van Heeringen, Hendrik G Stunnenberg, Huiqing Zhou, Caterina Missero, Rose Anne Romano, Satrajit Sinha, Michael J Dixon, Jill Dixon
Cleft palate is a common congenital disorder that affects up to 1 in 2500 live births and results in considerable morbidity to affected individuals and their families. The aetiology of cleft palate is complex with both genetic and environmental factors implicated. Mutations in the transcription factor p63 are one of the major individual causes of cleft palate; however, the gene regulatory networks in which p63 functions remain only partially characterized. Our findings demonstrate that p63 functions as an essential regulatory molecule in the spatio-temporal control of palatal epithelial cell fate to ensure appropriate fusion of the palatal shelves...
June 12, 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28604150/breastfeeding-after-early-repair-of-cleft-lip-in-newborns-with-cleft-lip-or-cleft-lip-and-palate-in-a-baby-friendly-designated-hospital
#8
Iva Burianova, Katarina Kulihova, Veronika Vitkova, Jan Janota
BACKGROUND: Goals of treatment of orofacial cleft are to improve feeding, speech, hearing, and facial appearance. Early surgery brings faster healing, better cosmetic effect, and fewer complications. Breastfeeding rates after early surgery are unknown. Early repair of the cleft lip may influence breastfeeding rates. Research aim: The aim of this study was to evaluate breastfeeding after early repair of the cleft lip in a Baby-Friendly designated hospital. The rate of breastfeeding in newborns with cleft lip was compared to cleft lip and palate...
June 1, 2017: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
https://www.readbyqxmd.com/read/28603561/distinct-dna-methylation-profiles-in-subtypes-of-orofacial-cleft
#9
Gemma C Sharp, Karen Ho, Amy Davies, Evie Stergiakouli, Kerry Humphries, Wendy McArdle, Jonathan Sandy, George Davey Smith, Sarah J Lewis, Caroline L Relton
BACKGROUND: Epigenetic data could help identify risk factors for orofacial clefts, either by revealing a causal role for epigenetic mechanisms in causing clefts or by capturing information about causal genetic or environmental factors. Given the evidence that different subtypes of orofacial cleft have distinct aetiologies, we explored whether children with different cleft subtypes showed distinct epigenetic profiles. METHODS: In whole-blood samples from 150 children from the Cleft Collective cohort study, we measured DNA methylation at over 450,000 sites on the genome...
2017: Clinical Epigenetics
https://www.readbyqxmd.com/read/28600484/perinatal-case-of-fatal-simpson-golabi-behmel-syndrome-with-hyperplasia-of-seminiferous-tubules
#10
Nives Zimmermann, Jerzy Stanek
BACKGROUND Simpson-Golabi-Behmel syndrome (SGBS) is a rare X-linked recessive syndrome characterized by fetal overgrowth. CASE REPORT We present a case of a male infant with SGBS. Abnormal prenatal ultrasound (including congenital diaphragmatic hernia) prompted microarray testing of amniotic fluid cells, which showed deletion on chromosome Xq26.2 affecting the glypican-3 gene consistent with SGBS type I. The infant died six hours after birth and at autopsy showed features of SGBS, including macrosomia, organomegaly, diaphragmatic hernia with consequent pulmonary hypoplasia, cleft palate, large tongue with a midline groove, a supernumerary nipple, Meckel's diverticulum, and abnormal phalanges...
June 10, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28599592/prenatal-diagnosis-of-foetal-cleft-palate-on-the-axial-view-in-the-first-trimester-with-the-higher-frequency-curved-transducer
#11
Yan Yi, Tong Tong, Tao Liu, Qi Lin, Yi Xiong, Jinfeng Xu
No abstract text is available yet for this article.
June 9, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28597839/-timing-of-alveolar-bone-graft-and-sequences-of-canine-eruption-in-cases-of-cleft-lip-and-palate-a-systematic-review
#12
Rajae Elhaddaoui, Loubna Bahije, Fatima Zaoui, Wiam Rerhrhaye
INTRODUCTION: The alveolar bone graft (ABG) is an important phase in the surgical treatment of cleft lip and palate (CLP). The purpose of alveolar bone grafting is to eliminate oronasal fistulas, restore the continuity of the maxilla and provide optimal periodontal support for spontaneous eruption of permanent canines adjacent to the cleft. The purpose of this systematic review was to determine the ideal timing of the ABG that would achieve these goals. MATERIAL AND METHODS: Databases consulted were MEDLINE, Embase et EBSCOhost, using keywords present in the MeSH: [cleft lip and palate] and [alveolar bone graft] and [tooth eruption]...
June 2017: L' Orthodontie Française
https://www.readbyqxmd.com/read/28594978/association-of-gel-forming-mucins-and-aquaporin-gene-expression-with-hearing-loss-effusion-viscosity-and-inflammation-in-otitis-media-with-effusion
#13
Tina L Samuels, Justin C Yan, Pawjai Khampang, Peter W Dettmar, Alexander MacKinnon, Wenzhou Hong, Nikki Johnston, Blake C Papsin, Robert H Chun, Michael E McCormick, Joseph E Kerschner
Importance: Persistent, viscous middle ear effusion in pediatric otitis media (OM) contributes to increased likelihood of anesthesia and surgery, conductive hearing loss, and subsequent developmental delays. Biomarkers of effusion viscosity and hearing loss have not yet been identified despite the potential that such markers hold for targeted therapy and screening. Objective: To investigate the association of gel-forming mucins and aquaporin 5 (AQP5) gene expression with inflammation, effusion viscosity, and hearing loss in pediatric OM with effusion (OME)...
June 8, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28592063/-effect-of-cisatracurium-on-entropy-index-of-children-undergoing-sevoflurane-anesthesia
#14
J Cao, X T Zhang, D W Hu, W J Zhu
Objective: To investigate the effect of cisatracurium on entropy index of children undergoing sevoflurane anesthesia. Methods: Forty-five child patients (ASAⅠ-Ⅱ) who underwent cleft lip and palate repair surgery in Beijing Stomatological Hospital were selected from June to November in 2015. They aged from 8 to 24 months and were randomly divided into 3 groups, as well as maintained at different end-tidal sevoflurane concentrations (C(ET)Sev), respectively. The C(ET)Sev in Group Ⅰ was 2.5%, with a total number of 15 cases...
May 30, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28591521/changes-in-face-specific-neural-processing-explain-reduced-cuteness-and-approachability-of-infants-with-cleft-lip
#15
Renske Huffmeijer, Janna Eilander, Viara R Mileva-Seitz, Ralph C A Rippe
The current study investigated whether changes in the neural processing of faces of infants with a facial abnormality - a cleft lip - mediate effects of the cleft lip on judgments of infant cuteness and approachability. Event-related potentials (ERPs) in response to pictures of faces of healthy infants and infants with a cleft lip, and ratings of cuteness and approachability of these infant faces, were obtained from 30 females. Infants with a cleft lip were rated as less attractive (less cute and approachable) than healthy infants, and both the N170 and P2 components of the ERP were of reduced amplitude in response to pictures of infants with a cleft lip...
June 18, 2017: Social Neuroscience
https://www.readbyqxmd.com/read/28591242/3d-analysis-of-effects-of-primary-surgeries-in-cleft-lip-palate-children-during-the-first-two-years-of-life
#16
Karine Laskos Sakoda, Paula Karine Jorge, Cleide Felício Carvalho Carrara, Maria Aparecida de Andrade Moreira Machado, Fabrício Pinelli Valarelli, Arnaldo Pinzan, Thais Marchini Oliveira
This study aimed at monitoring the maxillary growth of children with cleft lip/palate in the first two years of life, and to evaluate the effects of primary surgeries on dental arch dimensions. The sample consisted of the three-dimensional digital models of 25 subjects with unilateral complete cleft lip and palate (UCLP) and 29 subjects with isolated cleft palate (CP). Maxillary arch dimensions were measured at 3 months (before lip repair), 1 year (before palate repair), and at 2 years of age. Student's ttest was used for comparison between the groups...
June 5, 2017: Brazilian Oral Research
https://www.readbyqxmd.com/read/28590972/response-crowdsourcing-as-a-novel-method-to-evaluate-esthetic-outcomes-of-treatment-for-unilateral-cleft-lip
#17
Eugene Oh, Bryan A Comstock, Joseph Gruss, Richard Hopper, Craig Birgfeld, Raymond Tse
No abstract text is available yet for this article.
June 6, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28590970/letter-to-the-editor-response-to-crowdsourcing-as-a-novel-method-to-evaluate-aesthetic-outcomes-of-treatment-for-unilateral-cleft-lip
#18
Janak Bechar, Ting-Li Su, Bruce Richard
No abstract text is available yet for this article.
June 6, 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28589475/cleft-palate-with-without-cleft-lip-in-french-children-radiographic-evaluation-of-prevalence-location-and-coexistence-of-dental-anomalies-inside-and-outside-cleft-region
#19
Francesca Mangione, Laure Nguyen, Nathalie Foumou, Emmanuelle Bocquet, Elisabeth Dursun
INTRODUCTION: Prevalence of dental anomalies in cleft patients is higher than that in general population. The objectives of this study were to assess the prevalence of dental anomalies and their coexistence in French children with cleft and, then, to investigate the relation between the dental anomalies and the cleft type. MATERIAL AND METHODS: Seventy-four non-syndromic cleft patients (6-16 years old) from Lille Regional University and Mondor-Chenevier Hospitals (France) were included...
June 7, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/28588975/economic-valuation-of-the-impact-of-a-large-surgical-charity-using-the-value-of-lost-welfare-approach
#20
Daniel Scott Corlew, Blake C Alkire, Dan Poenaru, John G Meara, Mark G Shrime
BACKGROUND: The assessment of the economic burden of surgical disease is integral to determining allocation of resources for health globally. We estimate the economic gain realised over an 11-year period resulting from a vertical surgical programme addressing cleft lip (CL) and cleft palate (CP). METHODS: The database from a large non-governmental organisation (Smile Train) over an 11-year period was analysed. Incidence-based disability-adjusted life years (DALYs) averted through the programme were calculated, discounted 3%, using disability weights from the Global Burden of Disease (GBD) study and an effectiveness factor for each surgical intervention...
November 2016: BMJ Global Health
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