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Keywords Deep vein thrombosis and pulmo...

Deep vein thrombosis and pulmonary embolism

https://read.qxmd.com/read/38537124/genetically-identifying-the-thrombo-embolic-in-cteph
#1
JOURNAL ARTICLE
Christina A Eichstaedt
No abstract text is available yet for this article.
March 27, 2024: American Journal of Respiratory and Critical Care Medicine
https://read.qxmd.com/read/38532938/real-world-data-on-treatment-patterns-and-bleeding-in-cancer-associated-thrombosis-data-from-the-troll-registry
#2
JOURNAL ARTICLE
Zygimantas Zaboras, Camilla Tøvik Jørgensen, Andreas Stensvold, Heidi Hassel Pettersen, Aleksandra Galovic Grdinic, Sigrid Kufaas Brækkan, Waleed Ghanima, Mazdak Tavoly
Background  International guidelines are increasingly recommending direct oral anticoagulants (DOACs) as the first-line treatment for cancer-associated thrombosis (CAT). However, data regarding treatment patterns and adherence to guidelines in patients with CAT are scarce. Objectives  This study aimed to explore anticoagulant treatment patterns in patients with CAT and to calculate the incidence rates of bleeding events. Methods  Patients ≥18 years with active cancer and a first-time venous thromboembolism between 2005 and 2020 were identified through the Venous T hrombosis R egistry in Østf OL d Hospita L ...
January 2024: TH Open: Companion Journal to Thrombosis and Haemostasis
https://read.qxmd.com/read/38531094/syringe-assisted-test-aspiration-with-mechanical-aspiration-thrombectomy-results-in-good-safety-and-short-term-outcomes-in-the-treatment-of-patients-with-deep-venous-thrombosis
#3
JOURNAL ARTICLE
Wanglong Li, Yichen Lin, Kunfeng Su, Fanggang Cai, Jinchi Zhang, Xiaoling Lai, Xiaoqi Zheng, Pingfan Guo, Xinhuang Hou, Yiquan Dai
OBJECTIVE: To evaluate the short-term outcomes and safety of syringe-assisted test-aspiration with mechanical aspiration thrombectomy in the treatment of deep venous thrombosis. METHODS: This was a single-center, retrospective study of hospitalized patients with iliofemoral and/or inferior vena caval deep venous thrombosis, excluding those with pulmonary embolism. We collected the following patient data from the electronic medical records: age, sex, provoked/unprovoked deep venous thrombosis, symptom duration, thrombosed segments, and the presence of a tumor, thrombophilia, diabetes, and/or iliac vein compression syndrome...
March 26, 2024: Vascular
https://read.qxmd.com/read/38529544/incidence-of-symptomatic-venous-thromboembolisms-in-stroke-patients
#4
JOURNAL ARTICLE
Mostafa Al Turk, Michael Abraham
Venous thromboembolism (VTE) is a common but preventable complication observed in critically ill patients. Deep vein thrombosis (DVT) is the most common type of VTE, with clinical significance based on location and symptoms. There is an increased incidence of DVT and pulmonary embolism (PE) in ischemic stroke patients using unfractionated heparin (UFH) for VTE prophylaxis compared with those using enoxaparin. However, UFH is still used in some patients due to its perceived safety, despite conflicting literature suggesting that enoxaparin may have a protective effect...
March 26, 2024: Journal of Intensive Care Medicine
https://read.qxmd.com/read/38523134/american-association-for-the-surgery-of-trauma-american-college-of-surgeons-committee-on-trauma-clinical-protocol-for-post-discharge-venous-thromboembolism-prophylaxis-after-trauma
#5
JOURNAL ARTICLE
Allison E Berndtson, Alisa Cross, Brian K Yorkgitis, Ryan Kennedy, Matthew P Kochuba, Christopher Tignanelli, Gail T Tominaga, David G Jacobs, Dennis W Ashley, Eric J Ley, Lena Napolitano, Todd W Costantini
Trauma patients are at an elevated risk for developing venous thromboembolism (VTE), which includes pulmonary embolism and deep vein thrombosis. In the inpatient setting, prompt pharmacologic prophylaxis is utilized to prevent VTE. For patients with lower extremity fractures or limited mobility, VTE risk does not return to baseline levels post-discharge. Currently, there are limited data to guide post-discharge VTE prophylaxis in trauma patients. The goal of these post-discharge VTE prophylaxis guidelines are to identify patients at the highest risk of developing VTE after discharge and to offer pharmacologic prophylaxis strategies to limit this risk...
March 25, 2024: Journal of Trauma and Acute Care Surgery
https://read.qxmd.com/read/38522096/machine-learning-natural-language-processing-for-identifying-venous-thromboembolism-systematic-review-and-meta-analysis
#6
JOURNAL ARTICLE
Barbara D Lam, Pavlina Chrysafi, Thita Chiasakul, Harshit Khosla, Dimitra Karagkouni, Megan McNichol, Alys Adamski, Nimia Reyes, Karon Abe, Simon Mantha, Ioannis S Vlachos, Jeffrey I Zwicker, Rushad Patell
Venous thromboembolism (VTE) is a leading cause of preventable in-hospital mortality. Monitoring VTE cases is limited by the challenges of manual chart review and diagnosis code interpretation. Natural language processing (NLP) can automate the process. Rule-based NLP methods are effective but time consuming. Machine learning (ML)-NLP methods present a promising solution. We conducted a systematic review and meta-analysis of studies published before May 2023 that use ML-NLP to identify VTE diagnoses in the electronic health records...
March 24, 2024: Blood Advances
https://read.qxmd.com/read/38510368/anticoagulation-management-in-elderly-patients-with-proximal-femur-fractures%C3%A2-overview-of-current-concepts
#7
REVIEW
Yasmin Youssef, Anna K I M Dietrich, Annika Hättich
OBJECTIVES: Proximal femur fractures (PFF) are common injuries in elderly patients and can have considerable effects on their quality of life, morbidity, and mortality. Due to pre-existing comorbidities, the prevalence of anticoagulated patients is increasing. The right timing for surgery and perioperative anticoagulation treatment remains controversial. CONTENT: This overview aims to summarize current practices in the pre- and postoperative anticoagulation management and the recommended time to surgery in elderly patients with PFF...
December 2023: Innovative Surgical Sciences
https://read.qxmd.com/read/38510098/endovascular-release-of-an-adams-deweese-clip-and-iliocaval-reconstruction-for-debilitating-lower-extremity-swelling
#8
Eric Sung, Joel L Ramirez, Devin Zarkowsky
More than 10 million cases of venous thromboembolisms are reported on an annual basis and are major contributors to morbidity and mortality. Studies have found that ≤90% of pulmonary embolisms originate from the abdominal and lower extremity veins. The mainstay of venous thromboembolism treatment has been, and still continues to be, anticoagulation. However, for patients for whom anticoagulation is contraindicated or has failed, physicians have turned to surgical innovations such as inferior vena cava (IVC) filters to create partial interruption of the IVC...
June 2024: Journal of Vascular Surgery Cases and Innovative Techniques
https://read.qxmd.com/read/38509585/renal-damage-and-old-age-risk-factors-for-thrombosis-in-patients-with-anca-associated-vasculitis
#9
JOURNAL ARTICLE
Xin Chen, Shuo Zhang, Ruilian You, Yixin Ma, Peng Xia, Xiaoxiao Shi, Haiting Wu, Ke Zheng, Yan Qin, Xinping Tian, Limeng Chen
INTRODUCTION: Thrombosis in ANCA-associated vasculitis (AAV) was prevalent and has been neglected in Chinese patients. This study tried to describe the clinical characteristics, identify the risk factors, and investigate the causal relationship between AAV and venous thromboembolism (VTE) by two-sample Mendelian randomization (MR) analysis. METHODS: In this retrospective, observational study, we included all hospitalized AAV patients from Jan 2013 to Apr 2022 in Peking Union Medical College Hospital...
March 20, 2024: Thrombosis Journal
https://read.qxmd.com/read/38509493/analysis-of-the-incidence-and-risk-factors-of-blood-transfusion-in-total-knee-revision-a-retrospective-nationwide-inpatient-sample-database-study
#10
JOURNAL ARTICLE
Xiaoyin Li, Hao Xie, Shuxia Liu, Jian Wang, Zhanjun Shi, Qiaobing Yao, Qinfeng Yang, Qiuhong Li, Liangxiao Bao
OBJECTIVE: This study sought to determine the incidence and risk factors of blood transfusion among patients undergoing total knee revision (TKR) using a nationwide database. METHODS: A retrospective data analysis was conducted based on the Nationwide Inpatient Sample (NIS), enrolling patients who underwent TKR from 2010 to 2019 with complete information. The patients were divided into two groups based on whether they received blood transfusion or not. The demographic characteristics (race, sex, and age), length of stay (LOS), total charge of hospitalization, hospital characteristics (admission type, insurance type, bed size, teaching status, location, and region of hospital), hospital mortality, comorbidities, and perioperative complications were analyzed...
March 20, 2024: BMC Musculoskeletal Disorders
https://read.qxmd.com/read/38503987/advances-in-d-dimer-testing-progress-in-harmonization-of-clinical-assays-and-innovative-detection-methods
#11
REVIEW
Rong Zhao, Mengran Li, Peng Xiao, Dewei Song, Hongmei Li
The D-dimer is a sensitive indicator of coagulation and fibrinolysis activation, especially valuable as a biomarker of intravascular thrombosis. Measurement of plasma D-dimer levels plays a crucial role in the diagnosis and monitoring of conditions such as deep vein thrombosis, pulmonary embolism, and disseminated intravascular coagulation. A variety of immunoassays, including enzyme-linked immunosorbent assays, latex-enhanced immunoturbidimetric assays, whole-blood aggregation analysis, and immunochromatography assays, are widely used in clinical settings to determine D-dimer levels...
March 20, 2024: Analytical and Bioanalytical Chemistry
https://read.qxmd.com/read/38493553/quality-of-referrals-for-lower-extremity-ultrasonography-and-computed-tomography-pulmonary-angiography-and-associations-with-positive-findings-of-venous-thromboembolism
#12
JOURNAL ARTICLE
S Naimi, K J Ødegaard, K K Jenssen, P M Lauritzen
INTRODUCTION: The referral is the basis for radiologists' assessment of modality, protocol and urgency, and insufficient information may threaten patient safety. The aim of this study was to assess the completeness of referrals for lower extremity venous duplex ultrasonography (LEVDUS) and computed tomography pulmonary angiography (CTPA), and to investigate associations between the provided clinical information including risk factors, symptoms and lab results in the referrals and positive findings of deep vein thrombosis (DVT) and pulmonary embolism (PE), respectively...
March 16, 2024: Radiography
https://read.qxmd.com/read/38490955/diagnosis-and-treatment-of-venous-thromboembolism-during-pregnancy-relate-to-genetic-polymorphism
#13
REVIEW
Qingcheng Yang, Xuechang Wang, Rui Wang, Aihua Li
OBJECTIVES: Previous research had shown that age, a positive family history, comorbidities, major surgical operations, gestation, and use of several medications could increase the incidence of venous thromboembolism (VTE). With the development of medical and clinical individualized treatment, many people exposed to above risk factors did not develop VTE, suggested that genetic factors are also involved in the development of VTE. In this review, we aim to summarize VTE diagnosis and treatment in pregnancy women related to gene polymorphism...
March 15, 2024: Vascular
https://read.qxmd.com/read/38489062/safety-of-biological-therapies-for-severe-asthma-an-analysis-of-suspected-adverse-reactions-reported-in-the-who-pharmacovigilance-database
#14
JOURNAL ARTICLE
Paola Maria Cutroneo, Elena Arzenton, Fabiana Furci, Fabio Scapini, Maria Bulzomì, Nicoletta Luxi, Marco Caminati, Gianenrico Senna, Ugo Moretti, Gianluca Trifirò
BACKGROUND: The management of uncontrolled severe asthma has greatly improved since the advent of novel biologic therapies. Up to August 2022, five biologics have been approved for the type 2 asthma phenotype: anti-IgE (omalizumab), anti-IL5 (mepolizumab, reslizumab, benralizumab), and anti-IL4 (dupilumab) monoclonal antibodies. These drugs are usually well tolerated, although long-term safety information is limited, and some adverse events have not yet been fully characterized. Spontaneous reporting systems represent the cornerstone for the detection of potential signals and evaluation of the real-world safety of all marketed drugs...
March 15, 2024: BioDrugs: Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy
https://read.qxmd.com/read/38487548/the-paradigm-shift-in-treatment-of-severe-venous-thromboembolism
#15
REVIEW
Fábio Henrique Rossi, Francisco José Osse, Patricia Ellen Thorpe
Pulmonary embolism (PE) is the third leading cause of cardiovascular death and the main cause of preventable in-hospital death in the world. The PERT® (Pulmonary Embolism Response Team) concept involves multidisciplinary diagnosis and immediate treatment. Deep venous thrombosis (DVT) is the initial cause of most cases of PE and is responsible for complications such as chronic thromboembolic recurrence, postthrombotic syndrome, and chronic thromboembolic pulmonary hypertension. An aggressive approach to severe cases of iliofemoral DVT similar to the PERT® system can not only reduce the immediate risk of PE and death but can also reduce later sequelae...
2024: Jornal Vascular Brasileiro
https://read.qxmd.com/read/38484689/impact-of-blood-lipid-levels-on-venous-thromboembolism-in-acute-stroke-patients
#16
JOURNAL ARTICLE
Jiapei Wei, Yupeng Liu, Xiaoqin Lu, Liying Chen
BACKGROUND: Venous thromboembolism (VTE), including deep vein thrombosis (DVT) and pulmonary embolism (PE), is a common complication of stroke with a high incidence of underdiagnosis. The relationship between dyslipidemia and VTE remains uncertain. Therefore, this study aimed to explore this connection in acute stroke patients to enhance diagnostic and preventative strategies. METHODS: Retrospective data from 7854 acute stroke patients admitted to Dongyang Hospital, Affiliated with Wenzhou Medical University, between 2010 and 2020 were extracted...
March 13, 2024: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://read.qxmd.com/read/38483845/ultrasound-assisted-catheter-directed-thrombolysis-for-the-management-of-pulmonary-embolism-a-single-center-experience-in-a-community-hospital
#17
JOURNAL ARTICLE
Jasmine Ventenilla, Todd Rushing, Becky Ngu, David Shavelle, Neepa Rai
Current guidelines recommend anticoagulation alone for low-risk pulmonary embolism (PE) with the addition of systemic thrombolysis for high-risk PE. However, treatment recommendations for intermediate-risk PE are not well-defined. Due to bleeding risks associated with systemic thrombolysis, ultrasound-assisted catheter-directed thrombolysis (USAT) has evolved as a promising treatment modality. USAT is thought to decrease the rate of major bleeding by using localized delivery with lower thrombolytic dosages...
2024: Journal of Cardiovascular Pharmacology and Therapeutics
https://read.qxmd.com/read/38482093/pulmonary-embolism-in-a-patient-with-rheumatoid-arthritis-on-etanercept-therapy
#18
Moni Roy, Himanshu Rathore, Ashish K Roy
Pulmonary embolism (PE) represents mechanical obstruction of one or more branches of pulmonary vasculature due to thromboembolism from a deep vein thrombosis. Hormonal contraceptives, hormonal replacement therapy, antipsychotics and fibrates are medications that are associated with increased risk of venous thromboembolism(VTE). Etanercept is a TNF alpha and beta receptor blocker. Rarely this medication has been identified as a risk factor for VTE. There is a possible correlation between rheumatoid arthritis(RA) and risk of VTE in patients with RA...
2024: Journal of Community Hospital Internal Medicine Perspectives
https://read.qxmd.com/read/38481541/tranexamic-acid-in-upper-gastrointestinal-bleeding-is-associated-with-venous-and-arterial-thromboembolic-events
#19
JOURNAL ARTICLE
Cosmo Fowler, Jason Nasser, Brittany Fera, Lauren Chism, Stephen M Pastores
OBJECTIVES: To determine the risk difference of arterial and venous thromboembolic events between patients with upper gastrointestinal bleeding (UGIB) who received and did not receive tranexamic acid. DESIGN: Retrospective cohort study. SETTING: The TriNetX Analytics (Cambridge, MA) Research Network, a deidentified mixed electronic health record and claims-derived database with over 110 million patients, primarily located in the United States...
March 2024: Critical care explorations
https://read.qxmd.com/read/38481002/risk-of-venous-thromboembolism-with-tofacitinib-versus-tumor-necrosis-factor-inhibitors-in-cardiovascular-risk-enriched-rheumatoid-arthritis-patients
#20
JOURNAL ARTICLE
Christina Charles-Schoeman, Roy Fleischmann, Eduardo Mysler, Maria Greenwald, Steven R Ytterberg, Gary G Koch, Deepak L Bhatt, Cunshan Wang, Ted R Mikuls, All-Shine Chen, Carol A Connell, John C Woolcott, Sujatha Menon, Yan Chen, Kristen Lee, Zoltán Szekanecz
OBJECTIVE: The ORAL Surveillance trial found a dose-dependent increase in venous thromboembolism (VTE) and pulmonary embolism (PE) events with tofacitinib versus tumor necrosis factor inhibitors (TNFi). We aimed to assess VTE incidence over time and explore risk factors of VTE, including disease activity, in ORAL Surveillance. METHODS: Patients with rheumatoid arthritis (RA) aged ≥50 years with ≥1 additional cardiovascular risk factor received tofacitinib 5 or 10 mg twice daily (BID) or TNFi...
March 13, 2024: Arthritis & Rheumatology
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