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https://www.readbyqxmd.com/read/28922575/the-hospital-anxiety-and-depression-scale-factor-structure-and-psychometric-properties-in-older-adolescents-and-young-adults-with-autism-spectrum-disorder
#1
Mirko Uljarević, Amanda L Richdale, Helen McConachie, Darren Hedley, Ru Ying Cai, Hannah Merrick, Jeremy R Parr, Ann Le Couteur
Despite the high frequency of anxiety and depression symptoms in individuals with Autism Spectrum Disorder (ASD) and a significant impact of these comorbidities on both individuals with ASD and their families, research on the validity of anxiety and depression measures in the ASD population is currently lacking. The aim of this study was to explore the psychometric properties of the Hospital Anxiety and Depression Scale [HADS; Zigmond & Snaith, ] in a sample of older adolescents and young adults with ASD. One hundred and fifty one participants (UK Transition longitudinal study: N = 106; 75 males, Mage  = 16...
September 18, 2017: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/28922312/maximum-step-length-test-performance-in-people-with-parkinson-disease-a-cross-sectional-study
#2
Ryan P Duncan, Marie E McNeely, Gammon M Earhart
BACKGROUND AND PURPOSE: The Maximum Step Length Test (MSLT), a measure of one's capacity to produce a large step, has been studied in older adults, but not in people with Parkinson disease (PD). We characterized performance and construct validity of the MSLT in PD. METHODS: Forty participants (mean age: 65.12 ± 8.20 years; 45% female) with idiopathic PD completed the MSLT while "OFF" and "ON" anti-PD medication. Construct validity was investigated by examining relationships between MSLT and measures of motor performance...
October 2017: Journal of Neurologic Physical Therapy: JNPT
https://www.readbyqxmd.com/read/28922296/trajectories-of-glycemic-change-in-a-national-cohort-of-adults-with-previously-controlled-type-2-diabetes
#3
Rozalina G McCoy, Che Ngufor, Holly K Van Houten, Brian Caffo, Nilay D Shah
BACKGROUND: Individualized diabetes management would benefit from prospectively identifying well-controlled patients at risk of losing glycemic control. OBJECTIVES: To identify patterns of hemoglobin A1c (HbA1c) change among patients with stable controlled diabetes. RESEARCH DESIGN: Cohort study using OptumLabs Data Warehouse, 2001-2013. We develop and apply a machine learning framework that uses a Bayesian estimation of the mixture of generalized linear mixed effect models to discover glycemic trajectories, and a random forest feature contribution method to identify patient characteristics predictive of their future glycemic trajectories...
September 15, 2017: Medical Care
https://www.readbyqxmd.com/read/28922158/tailored-and-adaptive-computerized-cognitive-training-in-older-adults-at-risk-for-dementia-a-randomized-controlled-trial
#4
Alex Bahar-Fuchs, Shannon Webb, Lauren Bartsch, Linda Clare, George Rebok, Nicolas Cherbuin, Kaarin J Anstey
BACKGROUND: Computerized Cognitive Training (CCT) has been shown to improve cognitive function in older adults with mild cognitive impairment (MCI) or mood-related neuropsychiatric symptoms (MrNPS), but many questions remain unresolved. OBJECTIVE: To evaluate the extent to which CCT benefits older adults with both MCI and MrNPS, and its effects on meta-cognitive and non-cognitive outcomes, as well as establish whether adapting difficulty levels and tailoring to individuals' profile is superior to generic training...
September 11, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28922153/sex-dependent-associations-of-serum-uric-acid-with-brain-function-during-aging
#5
Alexandra M Kueider, Yang An, Toshiko Tanaka, Melissa H Kitner-Triolo, Stephanie Studenski, Luigi Ferrucci, Madhav Thambisetty
Serum uric acid (SUA) is an abundant natural antioxidant which could reduce the burden of cellular oxidation, a major cause of neurodegenerative disease. In line with this, SUA levels are lower in those with Alzheimer's disease; however, the association between SUA and cognition remains unclear. Results from studies examining the effects of SUA on cognition may be difficult to interpret in the context of normal versus pathological aging. This study examined sex-specific associations of baseline SUA with cognition during aging...
September 8, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28922149/the-relationships-between-components-of-metabolic-syndrome-and-mild-cognitive-impairment-subtypes-a-cross-sectional-study-of-japanese-older-adults
#6
Seongryu Bae, Hiroyuki Shimada, Sangyoon Lee, Hyuma Makizako, Sungchul Lee, Kazuhiro Harada, Takehiko Doi, Kota Tsutsumimoto, Ryo Hotta, Sho Nakakubo, Hyuntae Park, Takao Suzuki
BACKGROUND: The associations between components of metabolic syndrome (MetS) and mild cognitive impairment (MCI) subtypes remain unclear. OBJECTIVE: The study aim was to identify the prevalence of MetS for MCI subtypes and to investigate sex differences in the association between MetS and MCI subtypes in older Japanese adults. METHODS: The study analyzed data from 3,312 men and women aged 70 years or more. MetS was diagnosed according to International Diabetes Federation criteria...
September 8, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28922068/influence-of-flaxseed-lignan-supplementation-to-older-adults-on-biochemical-and-functional-outcome-measures-of-inflammation
#7
Yunyun Di, Jennifer Jones, Kerry Mansell, Susan Whiting, Sharyle Fowler, Lilian Thorpe, Jennifer Billinsky, Navita Viveky, Pui Chi Cheng, Ahmed Almousa, Thomas Hadjistavropoulos, Jane Alcorn
Evidence from the literature suggests that dietary flaxseed lignans have the ability to modulate inflammation, which is recognized as the underlying basis of multiple chronic human diseases in older adults. Our objective was to determine the effects of oral lignan supplementation on biochemical and functional indicators of inflammation as well as safety and tolerability in older healthy adults. We designed a randomized, double-blind, placebo-controlled clinical trial in older healthy adults (60-80 years) to assess flaxseed lignan-enriched complex (∼38% secoisolariciresinol diglucoside [SDG]; 600 mg SDG dose) oral supplementation effects on biochemical and functional indicators of inflammation and safety and tolerability in older healthy adults after 6 months of once-daily oral administration...
September 18, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28922050/how-to-interpret-high-levels-of-distress-when-using-the-distress-thermometer-in-the-long-term-follow-up-clinic-a-study-with-acute-lymphoblastic-leukemia-survivors
#8
A J Pépin, S Lippé, M Krajinovic, C Laverdière, B Michon, D Sinnett, S Sultan
OBJECTIVES: Recent guidelines recommend to assess emotional distress in pediatric oncology during treatment and in after care. One tool used to do this is the distress thermometer (DT), a simple tool which has almost exclusively been studied in its screening abilities. Given its increased used as a measure of distress per se, it is necessary to document its concurrent validity. The goal of this study was to identify clinical domains (eg, depression, anxiety) and individual symptoms associated with pediatric cancer survivors' rating on the DT...
September 18, 2017: Pediatric Hematology and Oncology
https://www.readbyqxmd.com/read/28921721/effects-of-the-availability-of-accurate-proprioceptive-information-on-older-adults-postural-sway-and-muscle-co-contraction
#9
Chesney E Craig, Glenn H M Calvert, Michail Doumas
During conditions of increased postural instability, older adults exhibit greater lower-limb muscle co-contraction. This response has been interpreted as a compensatory postural strategy, which may be used to i006Ecrease proprioceptive information from muscle spindles or to stiffen the lower limb as a general response to minimise postural sway. The current study aimed to test these two hypotheses by investigating use of muscle co-contraction during sensory transitions that manipulated proprioceptive input. Surface EMG was recorded from the bilateral tibialis anterior and gastrocnemius medialis muscles, in young (aged 18-30) and older adults (aged 68-80) during blind-folded postural assessment...
September 16, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28921685/four-year-incidence-rate-and-predictors-of-root-caries-among-community-dwelling-south-brazilian-older-adults
#10
Augusto B Bidinotto, Aline B Martins, Camila M Dos Santos, Fernando N Hugo, Juliana B Hilgert, Roger Keller Celeste, Dalva Maria Padilha, Renato José De Marchi
OBJECTIVE: This study aimed to assess the incidence density (ID) of new root caries lesions and restorations among community-living south Brazilian older adults and to assess its association with predictor variables. METHODS: We conducted a prospective cohort with a random sample of elders from the municipality of Carlos Barbosa, in south Brazil. Trained dentists performed interviews and oral examinations in 388 individuals at baseline, of which 273 were retained at follow-up 4 years later...
September 18, 2017: Community Dentistry and Oral Epidemiology
https://www.readbyqxmd.com/read/28921537/nasotracheal-intubation-over-a-bougie-vs-non-bougie-intubation-a-prospective-randomised-controlled-trial-in-older-children-and-adults-using-videolaryngoscopy
#11
R O Abrons, M B Zimmerman, Y M S El-Hattab
Conventionally, nasotracheal intubation has consisted of blind nasal passage and external manipulation of the tube through the glottis ('conventional technique'), a technique associated with a high incidence of nasal trauma. We evaluated a novel technique for routine asleep (i.e. post-induction) nasotracheal intubation using a bougie ('bougie technique'), which uses a nasopharyngeal airway to guide a paediatric bougie nasotracheally for use as a Seldinger tracheal intubation guide. Two hundred and fifty-seven older children (> 8 years) and adults were randomly assigned to videolaryngoscopy-assisted nasotracheal intubation using either the conventional or the bougie technique...
September 15, 2017: Anaesthesia
https://www.readbyqxmd.com/read/28921167/brain-structural-concomitants-of-resting-state-heart-rate-variability-in-the-young-and-old-evidence-from-two-independent-samples
#12
Hyun Joo Yoo, Julian F Thayer, Steven Greening, Tae-Ho Lee, Allison Ponzio, Jungwon Min, Michiko Sakaki, Lin Nga, Mara Mather, Julian Koenig
Previous research has shown associations between brain structure and resting state high-frequency heart rate variability (HF HRV). Age affects both brain structure and HF HRV. Therefore, we sought to examine the relationship between brain structure and HF HRV as a function of age. Data from two independent studies were used for the present analysis. Study 1 included 19 older adults (10 males, age range 62-78 years) and 19 younger adults (12 males, age range 19-37). Study 2 included 23 older adults (12 males; age range 55-75) and 27 younger adults (17 males; age range 18-34)...
September 18, 2017: Brain Structure & Function
https://www.readbyqxmd.com/read/28920567/electronic-devices-for-cognitive-impairment-screening-a-systematic-literature-review
#13
J Antonio García-Casal, Manuel Franco-Martín, M Victoria Perea-Bartolomé, J Miguel Toribio-Guzmán, Carlos García-Moja, Miguel Goñi-Imizcoz, Emese Csipke
OBJECTIVES: The reduction in cognitive decline depends on timely diagnosis. The aim of this systematic review was to analyze the current available information and communication technologies-based instruments for cognitive decline early screening and detection in terms of usability, validity, and reliability. METHODS: Electronic searches identified 1,785 articles of which thirty-four met the inclusion criteria and were grouped according to their main purpose into test batteries, measures of isolated tasks, behavioral measures, and diagnostic tools...
September 18, 2017: International Journal of Technology Assessment in Health Care
https://www.readbyqxmd.com/read/28920561/the-care-of-older-adults-experiencing-cognitive-challenges-how-interprofessional-teams-collaborate
#14
Sherry Dahlke, Salima Meherali, Thane Chambers, Rosalie Freund-Heritage, Kim Steil, Adrian Wagg
We conducted a scoping study to examine how interprofessional health care teams improve the outcomes of older adults experiencing cognitive challenges. We searched Ovid, Medline 1946, and MEDLINE In-Process and other non-indexed citations, using the concepts multi or interdisciplinary care teams, confusion or cognitive impairment, and elderly adults. Of 4,554 articles the review yielded, 34 relevant to our inquiry, using Arksey and O'Malley's methodological framework. Twenty-nine per cent of authors reported on the processes interprofessional teams use to achieve positive outcomes for older adults...
September 18, 2017: Canadian Journal on Aging, la Revue Canadienne du Vieillissement
https://www.readbyqxmd.com/read/28920550/sit-to-stand-activity-during-stroke-rehabilitation
#15
Andy Kerr, Jesse Dawson, Chris Robertson, Philip Rowe, Terence J Quinn
Objectives The sit to stand (STS) movement is key to independence and commonly affected by stroke. Repetitive practice is likely to improve STS ability during rehabilitation, however current practice levels are unknown. The objective of this study was simply to count the number of STS movements performed during the rehabilitation period of stroke patients using a physical activity monitor (PAM) and test whether being observed altered outcome. Methods Participants were medically stable patients referred for rehabilitation following stroke...
September 18, 2017: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/28920183/number-of-medications-or-number-of-diseases-what-influences-underprescribing
#16
Eva Cedilnik Gorup, Marija Petek Šter
PURPOSE: An increasing number of older adults suffer from multimorbidity and receive multiple medications. Despite that, underprescribing of potentially beneficial medications is widespread in this population. Our aim was to examine influence of polypharmacy and multimorbidity on the presence of prescribing omissions (PO) in general practice attenders. METHODS: We conducted a cross-sectional study of older adults attending general practices in Slovenia who were regularly prescribed at least one medication...
September 17, 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28920012/comparative-effectiveness-for-glycemic-control-in-older-adults-with-diabetes
#17
Michael Quartuccio, Brian Buta, Rita R Kalyani
PURPOSE OF REVIEW: To review and summarize the current data for comparative effectiveness of glycemic control in older adults. RECENT FINDINGS: In the last several years, professional societies have released guidelines for glycemic control in older adults, generally recommending individualized HbA1c goals. However, recent observational studies demonstrate that many older adults remain aggressively managed and are at increased risk of hypoglycemia. Large randomized trials of older adults with diabetes have failed to show cardiovascular benefit from intensive glycemic control and show only minimal microvascular benefit...
September 2017: Current Geriatrics Reports
https://www.readbyqxmd.com/read/28919930/effects-of-12-weeks-of-nordic-walking-and-xco-walking-training-on-the-endurance-capacity-of-older-adults
#18
Tobias Morat, Jenny Krueger, Angus Gaedtke, Manuela Preuss, Joachim Latsch, Hans-Georg Predel
BACKGROUND: Several studies have already examined the positive effects of various forms of endurance training in patient groups and in healthy adults up to 60 years old. The aim of this study was to analyse the effects of Nordic Walking (NW) and XCO Walking (XCO) training on endurance capacity in healthy older adults, aged 60 years and older. METHODS: Twenty-three older participants (mean age: 69.9 ± 5.4 years) were randomly assigned to either the NW group or the XCO group...
2017: European Review of Aging and Physical Activity
https://www.readbyqxmd.com/read/28919929/does-physical-activity-benefit-motor-performance-and-learning-of-upper-extremity-tasks-in-older-adults-a-systematic-review
#19
REVIEW
Lena Hübner, Claudia Voelcker-Rehage
Upper extremity motor performance declines with increasing age. However, older adults need to maintain, learn new and relearn known motor tasks. Research with young adults indicated that regular and acute physical activity might facilitate motor performance and motor learning processes. Therefore, this review aimed to examine the association between chronic physical activity and acute bouts of exercise on motor performance and motor learning in upper extremity motor tasks in older adults. Literature was searched via Cochrane library, PubMED, PsycINFO and Scopus and 27 studies met all inclusion criteria...
2017: European Review of Aging and Physical Activity
https://www.readbyqxmd.com/read/28919912/the-isfahan-comprehensive-elderly-study-objectives-research-design-methodology-and-preliminary-results
#20
Zahra Heidari, Awat Feizi
BACKGROUND: This paper presents the objectives, research design, methodology, and primary findings of the Isfahan Comprehensive Elderly Study (ICES). MATERIALS AND METHODS: In this cross-sectional study, 603 elderly persons (aged 60 and over) were selected by multistage cluster sampling method from Isfahan, Iran, in 2016 comprehensive questionnaires along with a detailed interview were used to collect information on personal, family, socioeconomic, health and social services characteristics, life styles, physical illnesses and chronic diseases, mental, emotional and cognition disorders, quality of life, disabilities, sleep quality, social supports, life satisfaction, self-efficacy, and of participants...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
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