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https://www.readbyqxmd.com/read/29021622/the-circadian-transcriptome-of-marine-fish-sparus-aurata-larvae-reveals-highly-synchronized-biological-processes-at-the-whole-organism-level
#1
M Yúfera, E Perera, J A Mata-Sotres, J Calduch-Giner, G Martínez-Rodríguez, J Pérez-Sánchez
The regulation of circadian gene expression remains largely unknown in farmed fish larvae. In this study, a high-density oligonucleotide microarray was used to examine the daily expression of 13,939 unique genes in whole gilthead sea bream (Sparus aurata) larvae with fast growth potentiality. Up to 2,229 genes were differentially expressed, and the first two components of Principal Component Analysis explained more than 81% of the total variance. Clustering analysis of differentially expressed genes identified 4 major clusters that were triggered sequentially, with a maximum expression at 0 h, 3 h, 9-15 h and 18-21 h zeitgeber time...
October 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29020220/role-of-secondary-prophylaxis-with-valganciclovir-in-the-prevention-of-recurrent-cytomegalovirus-disease-in-solid-organ-transplant-recipients
#2
Bradley J Gardiner, Jennifer K Chow, Lori Lyn Price, Natalie E Nierenberg, David M Kent, David R Snydman
Background: Cytomegalovirus (CMV) is a major contributor to morbidity and mortality in solid organ transplant recipients (SOTR). Ganciclovir and valganciclovir are highly effective antiviral drugs whose role in primary prophylaxis and treatment of CMV disease is well established. The objective of this study was to examine the effect of secondary prophylaxis (SP) on the risk of relapse in SOTR following an episode of CMV disease. Methods: We performed a retrospective cohort study of SOTR from 1995-2015 and used propensity score based inverse probability of treatment weighting methodology to control for confounding by indication...
August 7, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28986399/objectively-measured-physical-activity-sedentary-behavior-and-genetic-predisposition-to-obesity-in-us-hispanics-latinos-results-from-the-hispanic-community-health-study-study-of-latinos-hchs-sol
#3
Jee-Young Moon, Tao Wang, Tamar Sofer, Kari E North, Carmen R Isasi, Jianwen Cai, Marc D Gellman, Ashley E Moncrieft, Daniela Sotres-Alvarez, Maria Argos, Robert C Kaplan, Qibin Qi
Studies using self-reported data suggest gene-physical activity interaction on obesity, yet the influence of sedentary behavior, distinct from lack of physical activity, on genetic associations with obesity remains unclear. We analyzed interactions of accelerometer-measured moderate-to-vigorous physical activity (MVPA) and sedentary time with genetic variants on obesity among 9,645 US Hispanics/Latinos. An overall genetic risk score (GRS), central nervous system (CNS)-related GRS, and non-CNS GRS were calculated based on 97 BMI-associated SNPs...
October 6, 2017: Diabetes
https://www.readbyqxmd.com/read/28970105/sleep-patterns-and-hypertension-using-actigraphy-in-the-hispanic-community-health-study-study-of-latinos
#4
Alberto R Ramos, Jia Weng, Douglas M Wallace, Megan R Petrov, William K Wohlgemuth, Daniela Sotres-Alvarez, Jose S Loredo, Kathryn J Reid, Phyllis C Zee, Yasmin Mossavar-Rahmani, Sanjay R Patel
BACKGROUND: The aim of this study was to evaluate the association between actigraphy-based measures of sleep and prevalent hypertension in a sample of US Latinos. METHODS: We analyzed data from 2,148 participants of the Sueño Sleep Ancillary Study of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), who underwent 1 week of wrist actigraphy to characterize sleep duration, sleep efficiency, sleep fragmentation index, and daytime naps (≥ two naps of 15 minutes)...
September 29, 2017: Chest
https://www.readbyqxmd.com/read/28874520/sipp-a-novel-mitochondrial-phosphate-carrier-mediates-in-self-incompatibility
#5
Liliana Elizabeth Garcia-Valencia, Carlos Everardo Bravo-Alberto, Hen-Ming Wu, Rogelio Rodriguez-Sotres, Alice Y Cheung, Felipe Cruz-Garcia
In Solanaceae, the S-specific interaction between the pistil S-RNase and the pollen S-Locus F-box (SLF) protein control self-incompatibility (SI). Although this interaction defines the specificity of the pollen rejection response, the identification of three pistil essential modifier genes unlinked to the S-locus (HT-B, 120K and NaStEP), unveils a higher degree of complexity in the pollen rejection pathway. We showed previously that NaStEP, a stigma protein with homology with Kunitz-type protease inhibitors, is essential to SI in Nicotiana...
September 5, 2017: Plant Physiology
https://www.readbyqxmd.com/read/28870280/glucose-and-cholesterol-stabilization-in-patients-with-type-2-diabetes-mellitus-with-depressive-and-anxiety-symptoms-by-problem-solving-therapy-in-primary-care-centers-in-mexico-city
#6
Valerio Villamil-Salcedo, Blanca E Vargas-Terrez, Jorge Caraveo-Anduaga, Jorge González-Olvera, Adriana Díaz-Anzaldúa, José Cortés-Sotres, Magdalena Pérez-Ávila
Aim The aim of this study was to determine if the problem-solving therapy (PST) helps control metabolic variables in patients with type 2 diabetes mellitus (T2DM) who show depressive and anxiety symptoms. BACKGROUND: T2DM is a chronic-degenerative multifactorial disease. It is considered one of the main public health problems in the world, and it represents an important social and economic burden. It is frequently associated with major depression and anxiety disorders, which are related with high glycated hemoglobin (HbA1c) concentrations and poor metabolic control...
September 5, 2017: Primary Health Care Research & Development
https://www.readbyqxmd.com/read/28867291/cancer-recurrence-after-solid-organ-transplantation-a-systematic-review-and-meta-analysis
#7
REVIEW
Sergio A Acuna, Johnny W Huang, Fahima Dossa, Prakesh S Shah, S Joseph Kim, Nancy N Baxter
Solid organ transplant recipients (SOTR) with a pre-transplant malignancy (PTM) have been thought to be at high risk of cancer recurrence. However, recent population-based studies report cancer recurrence rates in SOTR similar to those of non-transplant patients. A systematic search was performed in MEDLINE, EMBASE, and Cochrane Library to identify studies reporting cancer recurrence in SOTR with PTM. Quality assessment was performed using a validated tool for assessing the quality of an observational study with no control group designed by the Institute of Health Economics...
August 10, 2017: Transplantation Reviews
https://www.readbyqxmd.com/read/28835368/prolonged-uninterrupted-sedentary-behavior-and-glycemic-biomarkers-among-us-hispanic-latino-adults-the-hchs-sol-hispanic-community-health-study-study-of-latinos
#8
MULTICENTER STUDY
Keith M Diaz, Jeff Goldsmith, Heather Greenlee, Garrett Strizich, Qibin Qi, Yasmin Mossavar-Rahmani, Denise C Vidot, Christina Buelna, Carrie E Brintz, Tali Elfassy, Linda C Gallo, Martha L Daviglus, Daniela Sotres-Alvarez, Robert C Kaplan
BACKGROUND: Excessive sedentary time is ubiquitous in developed nations and is associated with deleterious health outcomes. Few studies have examined whether the manner in which sedentary time is accrued (in short or long bouts) carries any clinical relevance. The purpose of this study was to examine the association of prolonged, uninterrupted sedentary behavior with glycemic biomarkers in a cohort of US Hispanic/Latino adults. METHODS: We studied 12 083 participants from the HCHS/SOL (Hispanic Community Health Study/Study of Latinos), a population-based study of Hispanic/Latino adults 18 to 74 years of age...
October 10, 2017: Circulation
https://www.readbyqxmd.com/read/28818366/expression-of-recombinant-snrk1-in-e-coli-characterization-of-adenine-nucleotide-binding-to-the-snrk1-1-akin%C3%AE-%C3%AE-%C3%AE-3-complex
#9
José Luis Maya-Bernal, Alejandra Ávila, Ana Ruiz-Gayosso, Ricardo Trejo-Fregoso, Nancy Pulido, Alejandro Sosa-Peinado, Esther Zúñiga-Sánchez, Eleazar Martínez-Barajas, Rogelio Rodríguez-Sotres, Patricia Coello
The SnRK1 complexes in plants belong to the family of AMPK/SNF1 kinases, which have been associated with the control of energy balance, in addition to being involved in the regulation of other aspects of plant growth and development. Analysis of complex formation indicates that increased activity is achieved when the catalytic subunit is phosphorylated and bound to regulatory subunits. SnRK1.1 subunit activity is higher than that of SnRK1.2, which also exhibits reduced activation due to the regulatory subunits...
October 2017: Plant Science: An International Journal of Experimental Plant Biology
https://www.readbyqxmd.com/read/28767517/accuracy-of-self-reported-weight-in-hispanic-latino-adults-of-the-hispanic-community-health-study-study-of-latinos
#10
Lindsay Fernández-Rhodes, Whitney R Robinson, Daniela Sotres-Alvarez, Nora Franceschini, Sheila F Castañeda, Christina Buelna, Ashley Moncrieft, Maria Llabre, Martha L Daviglus, Qibin Qi, Anita Agarwal, Carmen R Isasi, Paul Smokowski, Penny Gordon-Larsen, Kari E North
BACKGROUND: Previous US population-based studies have found that body weight may be underestimated when self-reported. However, this research may not apply to all US Hispanics/Latinos, many of whom are immigrants with distinct cultural orientations to ideal body size. We assessed the data quality and accuracy of self-reported weight in a diverse, community-based, US sample of primarily foreign-born Hispanic/Latino adults. METHODS: Using baseline data (2008-2011) from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), we described the difference between contemporaneous self-reported and measured current body weight (n = 16,119) and used multivariate adjusted models to establish whether the observed trends in misreporting in potential predictors of inaccuracy persisted after adjustment for other predictors...
November 2017: Epidemiology
https://www.readbyqxmd.com/read/28765082/is-there-a-relationship-between-accelerometer-assessed-physical-activity-and-sedentary-behavior-and-cognitive-function-in-us-hispanic-latino-adults-the-hispanic-community-health-study-study-of-latinos-hchs-sol
#11
Elizabeth Vásquez, Garrett Strizich, Carmen R Isasi, Sandra E Echeverria, Daniela Sotres-Alvarez, Kelly R Evenson, Marc D Gellman, Priya Palta, Qibin Qi, Melissa Lamar, Wassim Tarraf, Hector M González, Robert Kaplan
Normative changes in cognitive function are expected with increasing age. Research on the relationship between normative cognitive decline and moderate-to-vigorous physical activity (MVPA) and sedentary behavior (SED) needs further investigation in Hispanic/Latinos adults. We assessed the cross-sectional association between accelerometer assessed MVPA and SED with cognitive function in 7,478 adults aged 45-74years from the Hispanic Community Health Study/Study of Latinos. At baseline, cognitive tests included two executive function tests (Digit Symbol Substitution Test (DSST), a test of language (Word Fluency), and a test of memory (Spanish English Verbal Learning Test)...
July 29, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28761660/association-of-the-dash-dietary-pattern-with-insulin-resistance-and-diabetes-in-us-hispanic-latino-adults-results-from-the-hispanic-community-health-study-study-of-latinos-hchs-sol
#12
Leonor Corsino, Daniela Sotres-Alvarez, Nicole M Butera, Anna María Siega-Riz, Cristina Palacios, Cynthia M Pérez, Sandra S Albrecht, Rebecca A Espinoza Giacinto, Marisa Judith Perera, Linda Van Horn, M Larissa Avilés-Santa
OBJECTIVE: To examine the association between diet quality and both diabetes status and insulin resistance in Hispanic/Latino adults, and the extent to which differences in diet quality contribute to differences in outcomes across Hispanic/Latino heritage. RESEARCH DESIGN AND METHODS: Cross-sectional study. Data are from 15 942 individuals enrolled in the Hispanic Community Health Study/Study of Latinos. Diet was ascertained using two 24-hour dietary recalls, and diet quality was measured using the Dietary Approaches to Stop Hypertension (DASH) score (range: 0-80, lowest to highest)...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28736001/evaluating-retention-of-skin-cancer-education-in-kidney-transplant-recipients-reveals-a-window-of-opportunity-for-re-education
#13
P H Patel, K Bibee, G Lim, S M Malik, C Wu, M Pugliano-Mauro
BACKGROUND: Skin cancer is the most common malignancy after solid organ transplant and can lead to significant morbidity. The likelihood of developing squamous cell carcinomas and melanomas is 100 and 2.4 times more likely, respectively, in kidney transplant recipients when compared with the general population. There are few data regarding the assessment and influence of solid organ transplant recipient (SOTR) knowledge of skin cancer and its effect on short- and long-term awareness and behavior...
July 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28666597/diet-quality-inflammation-and-the-ankle-brachial-index-in-adults-with-or-without-cardiometabolic-conditions
#14
Josiemer Mattei, Daniela Sotres-Alvarez, Marc Gellman, Sheila F Castañeda, Frank B Hu, Katherine L Tucker, Anna Maria Siega-Riz, Robert C Kaplan
BACKGROUND & AIMS: Diet quality may influence non-traditional cardiovascular disease (CVD) risk factors - namely, C-reactive protein (CRP) and the ankle-brachial index (ABI). Pre-existing traditional cardiometabolic conditions may confound this association. We aimed to determine whether diet quality was associated with high-risk CRP or ABI, independently from traditional cardiometabolic risk factors. METHODS: Baseline data were analyzed from US-Hispanics/Latinos aged 18-74 y without previously-diagnosed CVD participating in the population-based Hispanic Community Health Study/Study of Latinos cohort...
June 8, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28546455/objectively-measured-sedentary-time-and-cardiovascular-risk-factor-control-in-us-hispanics-latinos-with-diabetes-mellitus-results-from-the-hispanic-community-health-study-study-of-latinos-hchs-sol
#15
Xueyin Wang, Garrett Strizich, Simin Hua, Daniela Sotres-Alvarez, Christina Buelna, Linda C Gallo, Marc D Gellman, Yasmin Mossavar-Rahmani, Matthew J O'Brien, Mark Stoutenberg, Tao Wang, M Larissa Avilés-Santa, Robert C Kaplan, Qibin Qi
BACKGROUND: Cardiovascular disease (CVD) risk factor control is a cornerstone of diabetes mellitus management. Little is known about relationships of objectively measured sedentary time and physical activity with major CVD risk factor control in individuals with diabetes mellitus. We examined associations of objectively measured sedentary time and moderate-to-vigorous physical activity with reaching major CVD risk factor control goals among US Hispanic/Latino adults with diabetes mellitus...
May 25, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28485086/uptake-of-cancer-screening-tests-among-recipients-of-solid-organ-transplantation
#16
S A Acuna, R Sutradhar, X Camacho, C Daly, M E Del Giudice, S J Kim, N N Baxter
Population-based cancer screening recommendations are also suggested for solid organ transplant recipients (SOTR); however, recommendation adherence is unknown. In a population-based cohort of SOTR in Ontario between 1997 and 2010, we determined the uptake of breast, cervical, and colorectal cancer screening tests and identified factors associated with up-to-date screening using recurrent event analysis. We identified 4436 SOTR eligible for colorectal, 2252 for cervical, and 1551 for breast cancer screening...
September 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28452165/cutaneous-toxicities-from-transplant-related-medications
#17
M Ilyas, O R Colegio, B Kaplan, A Sharma
Despite the abundance of information on cutaneous malignancies associated with solid organ transplantation in the transplant literature, there is limited information regarding non-malignant skin changes after transplantation. There are numerous skin toxicities secondary to immunosuppressive and other transplant-related medications that can vary in presentation, severity, and prognosis. In order to limit associated morbidity and mortality, SOTR care providers should effectively identify and manage cutaneous manifestations secondary to drug toxicity...
April 27, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28425766/update-in-the-treatment-of-non-influenza-respiratory-virus-infection-in-solid-organ-transplant-recipients
#18
REVIEW
Shellee A Grim, Gail E Reid, Nina M Clark
Despite the improved outcomes in solid organ transplantation with regard to prevention of rejection and increased patient and graft survival, infection remains a common cause of morbidity and mortality. Respiratory viruses are a frequent and potentially serious cause of infection after solid organ transplantation. Furthermore, clinical manifestations of respiratory virus infection (RVI) may be more severe and unusual in solid organ transplant recipients (SOTRs) compared with the non-immunocompromised population...
June 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/28422609/isotemporal-analysis-of-the-association-of-objectively-measured-physical-activity-with-depressive-symptoms-results-from-hispanic-community-health-study-study-of-latinos-hchs-sol
#19
Chad D Rethorst, Ashley E Moncrieft, Marc D Gellman, Elva M Arredondo, Christina Buelna, Shelia F Castañeda, Martha L Daviglus, Unab I Khan, Krista M Perreira, Daniela Sotres-Alvarez, Mark Stoutenberg
BACKGROUND: The burden of depression among Hispanics/Latinos indicates the need to identify factors related to depressive symptoms. This paper examines the relationship of physical activity (PA) and sedentary behavior (SB) with depressive symptoms in Hispanic/Latinos. METHODS: The Hispanic Community Health Study / Study of Latinos (HCHS/SOL) is a population-based, cohort study of Hispanic/Latinos in four United States metropolitan areas. Objectively measured PA was coded into: sedentary behavior (SB), light-intensity (LPA), moderate-intensity (MPA), and vigorous-intensity (VPA); and the Center for Epidemiological Studies Depression Scale-10 assessed depressive symptoms...
April 19, 2017: Journal of Physical Activity & Health
https://www.readbyqxmd.com/read/28407149/determination-of-the-biological-form-of-human-cytomegalovirus-dna-in-the-plasma-of-solid-organ-transplant-recipients
#20
Yupin Tong, Xiaoli L Pang, Curtis Mabilangan, Jutta K Preiksaitis
Background: Whether cytomegalovirus (CMV) DNA exists in plasma as virion-associated or free DNA is uncertain. Methods: An assay combining DNase I digestion and CMV quantitative polymerase chain reaction (DNase-CMV-qPCR) was developed to differentiate free naked DNA from virion DNA. One hundred three frozen and 10 fresh CMV DNA-positive plasma samples from solid-organ transplant recipients (SOTRs) were tested. Three sets of paired qPCR (P-qPCR) assays with amplicons of variable length were used to study CMV DNA fragmentation in 20 SOTR plasma samples, viral stocks (Towne, Merlin, AD169) and the first World Health Organization (WHO) international standard (IS) for CMV DNA...
April 1, 2017: Journal of Infectious Diseases
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