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https://www.readbyqxmd.com/read/28425766/update-in-the-treatment-of-non-influenza-respiratory-virus-infection-in-solid-organ-transplant-recipients
#1
Shellee A Grim, Gail E Reid, Nina M Clark
Despite the improved outcomes in solid organ transplantation with regard to prevention of rejection and increased patient and graft survival, infection remains a common cause of morbidity and mortality. Respiratory viruses are a frequent and potentially serious cause of infection after solid organ transplantation. Furthermore, clinical manifestations of respiratory virus infection (RVI) may be more severe and unusual in solid organ transplant recipients (SOTRs) compared with the non-immunocompromised population...
April 20, 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/28422609/isotemporal-analysis-of-the-association-of-objectively-measured-physical-activity-with-depressive-symptoms-results-from-hispanic-community-health-study-study-of-latinos-hchs-sol
#2
Chad D Rethorst, Ashley E Moncrieft, Marc D Gellman, Elva M Arredondo, Christina Buelna, Shelia F Castañeda, Martha L Daviglus, Unab I Khan, Krista M Perreira, Daniela Sotres-Alvarez, Mark Stoutenberg
BACKGROUND: The burden of depression among Hispanics/Latinos indicates the need to identify factors related to depressive symptoms. This paper examines the relationship of physical activity (PA) and sedentary behavior (SB) with depressive symptoms in Hispanic/Latinos. METHODS: The Hispanic Community Health Study / Study of Latinos (HCHS/SOL) is a population-based, cohort study of Hispanic/Latinos in four United States metropolitan areas. Objectively measured PA was coded into: sedentary behavior (SB), light-intensity (LPA), moderate-intensity (MPA), and vigorous-intensity (VPA); and the Center for Epidemiological Studies Depression Scale-10 assessed depressive symptoms...
April 19, 2017: Journal of Physical Activity & Health
https://www.readbyqxmd.com/read/28407149/determination-of-the-biological-form-of-human-cytomegalovirus-dna-in-the-plasma-of-solid-organ-transplant-recipients
#3
Yupin Tong, Xiaoli L Pang, Curtis Mabilangan, Jutta K Preiksaitis
Background.: Whether cytomegalovirus (CMV) DNA exists in plasma as virion-associated or free DNA is uncertain. Methods.: An assay combining DNase I digestion and CMV quantitative polymerase chain reaction (DNase-CMV-qPCR) was developed to differentiate free naked DNA from virion DNA. One hundred three frozen and 10 fresh CMV DNA-positive plasma samples from solid-organ transplant recipients (SOTRs) were tested. Three sets of paired qPCR (P-qPCR) assays with amplicons of variable length were used to study CMV DNA fragmentation in 20 SOTR plasma samples, viral stocks (Towne, Merlin, AD169) and the first World Health Organization (WHO) international standard (IS) for CMV DNA...
April 12, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28398853/the-association-of-parental-caregiver-chronic-stress-with-youth-obesity-findings-from-the-study-of-latino-youth-and-the-hispanic-community-health-study-study-of-latinos-sociocultural-ancillary-study
#4
Carmen R Isasi, Simin Hua, Molly Jung, Mercedes R Carnethon, Krista Perreira, Denise C Vidot, Christian R Salazar, Jessica L McCurley, Daniela Sotres-Alvarez, Linda Van Horn, Alan M Delamater, Maria M Llabre, Linda C Gallo
BACKGROUND: Prior studies indicate that chronic stress is associated with obesity in adults. However, whether parental/caregiver stress is associated with obesity in their offspring has not been widely examined in Hispanic/Latino populations. In this study, we evaluated the role of caregiver chronic stress on child obesity and whether home food environment or child lifestyle behaviors explained the association. METHODS: The study included a sample of Hispanic/Latino youth and their caregivers (n = 473) from the Study of Latinos (SOL) Youth study and the Hispanic Community Health Study/SOL Sociocultural Study, which enrolled children aged 8-16 years from four cities (Bronx, Chicago, Miami, and San Diego), and provided assessments of adult chronic stress...
March 1, 2017: Childhood Obesity
https://www.readbyqxmd.com/read/28364514/actigraphic-sleep-patterns-of-u-s-hispanics-the-hispanic-community-health-study-study-of-latinos
#5
Katherine A Dudley, Jia Weng, Daniela Sotres-Alvarez, Guido Simonelli, Elizabeth Cespedes Feliciano, Maricelle Ramirez, Alberto R Ramos, Jose S Loredo, Kathryn J Reid, Yasmin Mossavar-Rahmani, Phyllis C Zee, Diana A Chirinos, Linda C Gallo, Rui Wang, Sanjay R Patel
Study objective: To assess the extent to which objective sleep patterns vary among U.S. Hispanics/Latinos. Methods: We assessed objective sleep patterns in 2087 participants of the Hispanic Community Health Study/Study of Latinos from 6 Hispanic/Latino subgroups aged 18-64 years who underwent 7 days of wrist actigraphy. Results: The age- and sex-standardized mean (SE) sleep duration was 6.82 (0.05), 6.72 (0.07), 6.61 (0.07), 6.59 (0.06), 6...
February 1, 2017: Sleep
https://www.readbyqxmd.com/read/28364454/neighborhood-factors-as-predictors-of-poor-sleep-in-the-sue%C3%A3-o-ancillary-study-of-the-hispanic-community-health-study-study-of-latinos
#6
Guido Simonelli, Katherine A Dudley, Jia Weng, Linda C Gallo, Krista Perreira, Neomi A Shah, Carmela Alcantara, Phyllis C Zee, Alberto R Ramos, Maria M Llabre, Daniela Sotres-Alvarez, Rui Wang, Sanjay R Patel
Study Objectives: To evaluate whether an adverse neighborhood environment has higher prevalence of poor sleep in a US Hispanic/Latino population. Methods: A cross-sectional analysis was performed in 2156 US Hispanic/Latino participants aged 18-64 years from the Sueño ancillary study of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Participants completed surveys of neighborhood environment including perceived safety, violence and noise, the Insomnia Severity Index (ISI), and 7 days of wrist actigraphy...
January 1, 2017: Sleep
https://www.readbyqxmd.com/read/28362949/two-doses-of-inactivated-influenza-vaccine-improve-immune-response-in-solid-organ-transplant-recipients-results-of-transgripe-1-2-a-randomized-controlled-clinical-trial
#7
Elisa Cordero, Cristina Roca-Oporto, Angel Bulnes-Ramos, Teresa Aydillo, Joan Gavaldà, Asunción Moreno, Julián Torre-Cisneros, Jose Miguel Montejo, Jesús Fortun, Patricia Muñoz, Nuria Sabé, Maria Carmen Fariñas, Marino Blanes-Julia, Francisco López-Medrano, Alejandro Suárez-Benjumea, Juliana Martinez-Atienza, Clara Rosso-Fernández, Pilar Pérez-Romero
Background: Influenza vaccine effectiveness is not optimal in solid organ transplant recipients (SOTR). We hypothesized that a booster dose might increase it. Methods: TRANSGRIPE 1-2 is a phase 3, randomized, controlled, multicenter, open-label clinical trial. Patients were randomly assigned (1:1 stratified by study site, type of organ, and time since transplantation) to receive 1 dose (control group) or 2 doses (booster group) of the influenza vaccine 5 weeks apart...
April 1, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28349622/actigraphic-sleep-measures-and-diet-quality-in-the-hispanic-community-health-study-study-of-latinos-sue%C3%A3-o-ancillary-study
#8
Yasmin Mossavar-Rahmani, Jia Weng, Rui Wang, Pamela A Shaw, Molly Jung, Daniela Sotres-Alvarez, Sheila F Castañeda, Linda C Gallo, Marc D Gellman, Qibin Qi, Alberto R Ramos, Kathryn J Reid, Linda Van Horn, Sanjay R Patel
Using a cross-sectional probability sample with actigraphy data and two 24-h dietary recalls, we quantified the association between sleep duration, continuity, variability and timing with the Alternative Healthy Eating Index-2010 diet quality score and its components in 2140 Hispanic Community Health Study/Study of Latinos participants. The Alternative Healthy Eating Index diet quality-2010 score ranges from 0 to 110, with higher scores indicating greater adherence to the dietary guidelines and lower risk from major chronic disease...
March 28, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28347359/the-association-of-trajectories-of-protein-intake-and-age-specific-protein-intakes-from-2-to-22-years-with-bmi-in-early-adulthood
#9
Melecia Wright, Daniela Sotres-Alvarez, Michelle A Mendez, Linda Adair
No study has analysed how protein intake from early childhood to young adulthood relate to adult BMI in a single cohort. To estimate the association of protein intake at 2, 11, 15, 19 and 22 years with age- and sex-standardised BMI at 22 years (early adulthood), we used linear regression models with dietary and anthropometric data from a Filipino birth cohort (1985-2005, n 2586). We used latent growth curve analysis to identify trajectories of protein intake relative to age-specific recommended daily allowance (intake in g/kg body weight) from 2 to 22 years, then related trajectory membership to early adulthood BMI using linear regression models...
March 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28205551/applying-recovery-biomarkers-to-calibrate-self-report-measures-of-sodium-and-potassium-in-the-hispanic-community-health-study-study-of-latinos
#10
Y Mossavar-Rahmani, D Sotres-Alvarez, W W Wong, C M Loria, M D Gellman, L Van Horn, M H Alderman, J M Beasley, C M Lora, A M Siega-Riz, R C Kaplan, P A Shaw
Measurement error in assessment of sodium and potassium intake obscures associations with health outcomes. The level of this error in a diverse US Hispanic/Latino population is unknown. We investigated the measurement error in self-reported dietary intake of sodium and potassium and examined differences by background (Central American, Cuban, Dominican, Mexican, Puerto Rican and South American). In 2010-2012, we studied 447 participants aged 18-74 years from four communities (Miami, Bronx, Chicago and San Diego), obtaining objective 24-h urinary sodium and potassium excretion measures...
February 16, 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/28202188/rate-of-regional-nodal-metastases-of-cutaneous-squamous-cell-carcinoma-in-the-immunosuppressed-patient
#11
Eamon J McLaughlin, Lauren Miller, Thuzar M Shin, Joseph F Sobanko, Steven B Cannady, Christopher J Miller, Jason G Newman
PURPOSE: Immunosuppressed solid organ transplant recipients (SOTRs) have an increased risk of developing cutaneous squamous cell carcinomas (cSCCs) with metastatic potential. This study sought to determine the rate of regional lymph node involvement in a large cohort of solid organ transplant patients with cutaneous head and neck squamous cell carcinoma. MATERIALS AND METHODS: A retrospective chart review was performed on solid organ transplant patients with head and neck cutaneous squamous cell carcinoma treated at a tertiary academic medical center from 2005 to 2015...
February 4, 2017: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/28130624/psychosocial-factors-in-the-relationship-between-socioeconomic-status-and-cardiometabolic-risk-the-hchs-sol-sociocultural-ancillary-study
#12
Jessica L McCurley, Frank Penedo, Scott C Roesch, Carmen R Isasi, Mercedes Carnethon, Daniela Sotres-Alvarez, Neil Schneiderman, Patricia Gonzalez, Diana A Chirinos, Alvaro Camacho, Yanping Teng, Linda C Gallo
BACKGROUND: U.S. Hispanics/Latinos display a high prevalence of metabolic syndrome (MetSyn), a group of co-occurring cardiometabolic risk factors (abdominal obesity, impaired fasting glucose, dyslipidemia, elevated blood pressure) associated with higher cardiovascular disease and mortality risk. Low socioeconomic status (SES) is associated with higher risk for MetSyn in Hispanics/Latinos, and psychosocial factors may play a role in this relationship. PURPOSE: This cross-sectional study examined psychosocial factors in the association of SES and MetSyn components in 4,996 Hispanic/Latino adults from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) Sociocultural Ancillary Study...
January 27, 2017: Annals of Behavioral Medicine: a Publication of the Society of Behavioral Medicine
https://www.readbyqxmd.com/read/28093535/hepatitis-e-in-singapore-a-case-series-and-viral-phylodynamics-study
#13
Esmeralda Chi-Yuan Teo, Boon-Huan Tan, Michael A Purdy, Pui-San Wong, Pei-Jun Ting, Pik-Eu Jason Chang, Lynette Lin-Ean Oon, Amanda Sue, Chong-Gee Teo, Chee-Kiat Tan
The incidence of hepatitis E in Singapore appears to be increasing. A retrospective case-series study of patients diagnosed with hepatitis E in a tertiary hospital from 2009 to 2013 was conducted. Of 16 cases, eight (50%) were solid-organ transplant recipients (SOTRs), and 14 (88%) were found infected by genotype 3 hepatitis E virus (HEV-3). Bayesian inferences based on HEV subgenomic sequences from seven cases suggest that HEV-3 strains were introduced to Singapore as two principal lineages. Within limitations of the study, it can be inferred that one lineage, in the 3efg clade, emerged about 83 years ago, probably originating from Japan, whereas the other, in the 3abchij clade, emerged about 40 years ago, from the United States...
January 16, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/28024863/targeting-physical-activity-interventions-for-adults-when-should-intervention-occur
#14
Katelyn M Holliday, Dan Yu Lin, Sujatro Chakladar, Sheila F Castañeda, Martha L Daviglus, Kelly R Evenson, David X Marquez, Qibin Qi, Christina M Shay, Daniela Sotres-Alvarez, Denise C Vidot, Donglin Zeng, Christy L Avery
Understanding demographic differences in transitions across physical activity (PA) levels is important for informing PA-promoting interventions, yet few studies have examined these transitions in contemporary multi-ethnic adult populations. We estimated age-, race/ethnicity-, and sex-specific 1-year net transition probabilities (NTPs) for National Health and Nutrition Examination Survey (2007-2012, n=11,556) and Hispanic Community Health Study/Study of Latinos (2008-2011, n=15,585) adult participants using novel Markov-type state transition models developed for cross-sectional data...
April 2017: Preventive Medicine
https://www.readbyqxmd.com/read/27968992/evidence-for-a-non-overlapping-subcellular-localization-of-the-family-i-isoforms-of-soluble-inorganic-pyrophosphatase-in-arabidopsis-thaliana
#15
Francisca Morayna Gutiérrez-Luna, Ernesto Navarro de la Sancha, Lilián Gabriela Valencia-Turcotte, Sonia Vázquez-Santana, Rogelio Rodríguez-Sotres
Pyrophosphate is a byproduct of macromolecular biosynthesis and its degradation gives a thermodynamic impulse to cell growth. Soluble inorganic pyrophosphatases (PPa) are present in all living cells, but in plants and other Eukaryotes membrane-bound H+-pumping pyrophosphatases may compete with these soluble counterparts for the substrate. In Arabidopsis thaliana there are six genes encoding for classic family I PPa isoforms, five cytoplasmic, and one considered to be organellar. Here, six transgenic stable A...
December 2016: Plant Science: An International Journal of Experimental Plant Biology
https://www.readbyqxmd.com/read/27935792/youth-and-caregiver-physical-activity-and-sedentary-time-hchs-sol-youth
#16
Linda C Gallo, Scott P Roesch, Jessica L McCurley, Carmen R Isasi, Daniela Sotres-Alvarez, Alan M Delamater, Linda Van Horn, Elva M Arredondo, Krista M Perreira, Christina Buelna, Qibin Qi, Denise C Vidot, Mercedes R Carnethon
OBJECTIVES: We examined associations between youth and caregiver moderate/ vigorous physical activity (MVPA) and sedentary (SED) time, using accelerometery, in the Hispanic Community Health Study/Study of Latino Youth (HCHS/ SOL) Youth. METHODS: Participants were 623 caregivers and 877 youth 8-16 years old, enrolled in 2012-2014. Associations of youth and caregiver MVPA time, SED time, and meeting MVPA recommendations ( 150 min/week, adults; 420 min/week, youth) were examined in regression models that controlled for sample weights, design effects, and demographic and health covariates...
January 2017: American Journal of Health Behavior
https://www.readbyqxmd.com/read/27925576/comparison-of-oxygen-transfer-parameters-and-oxygen-demands-in-bioreactors-operated-at-low-and-high-dissolved-oxygen-levels
#17
Richard O Mines, Matthew C Callier, Benjamin J Drabek, André J Butler
The proper design of aeration systems for bioreactors is critical since it can represent up to 50% of the operational and capital cost at water reclamation facilities. Transferring the actual amount of oxygen needed to meet the oxygen demand of the wastewater requires α- and β-factors, which are used for calculating the actual oxygen transfer rate (AOTR) under process conditions based on the standard oxygen transfer rate (SOTR). The SOTR is measured in tap water at 20°C, 1 atmospheric pressure, and 0 mg L(-1) of dissolved oxygen (DO)...
March 21, 2017: Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering
https://www.readbyqxmd.com/read/27855733/actigraphic-sleep-patterns-of-u-s-hispanics-the-hispanic-community-health-study-study-of-latinos
#18
Katherine A Dudley, Jia Weng, Daniela Sotres-Alvarez, Guido Simonelli, Elizabeth Cespedes, Maricelle Ramirez, Alberto R Ramos, Jose S Loredo, Kathryn J Reid, Yasmin Mossavar-Rahmani, Phyllis C Zee, Diana A Chirinos, Linda C Gallo, Rui Wang, Sanjay R Patel
STUDY OBJECTIVE: To assess the extent to which objective sleep patterns vary among U.S. Hispanics/Latinos. METHODS: We assessed objective sleep patterns in 2,087 participants of the Hispanic Community Health Study/Study of Latinos from six Hispanic/Latino subgroups aged 18-64 years who underwent 7 days of wrist actigraphy. RESULTS: The age- and sex-standardized mean (SE) sleep duration was 6.82 (0.05), 6.72 (0.07), 6.61 (0.07), 6.59 (0.06), 6...
October 28, 2016: Sleep
https://www.readbyqxmd.com/read/27756543/analytical-and-biological-variability-in-biomarker-measurement-in-the-hispanic-community-health-study-study-of-latinos
#19
Bharat Thyagarajan, Annie Green Howard, Ramon Durazo-Arvizu, John H Eckfeldt, Marc D Gellman, Ryung S Kim, Kiang Liu, Armando J Mendez, Frank J Penedo, Gregory A Talavera, Marston E Youngblood, Lihui Zhao, Daniela Sotres-Alvarez
BACKGROUND: Biomarker variability, which includes within-individual variability (CVI), between-individual variability (CVG) and methodological variability (CVP+A) is an important determinant of our ability to detect biomarker-disease associations. Estimates of CVI and CVG may be population specific and little data exists on biomarker variability in diverse Hispanic populations. Hence, we evaluated all 3 components of biomarker variability in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) using repeat blood collections (n=58) and duplicate blood measurements (n=761-929 depending on the biomarker)...
December 1, 2016: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/27756004/design-of-a-potentially-prebiotic-and-responsive-encapsulation-material-for-probiotic-bacteria-based-on-chitosan-and-sulfated-%C3%AE-glucan
#20
Cigdem Yucel Falco, Javier Sotres, Ana Rascón, Jens Risbo, Marité Cárdenas
HYPOTHESIS: Chitosan and sulfated oat β-glucan are materials suitable to create a prebiotic coating for targeted delivery to gastrointestinal system, using the layer by layer technology. EXPERIMENT: Quartz crystal microbalance with dissipation (QCM-D), spectroscopic ellipsometry (SE) and atomic force microscopy (AFM) were used to assess the multilayer formation capacity and characterize the resulting coatings in terms of morphology and material properties such as structure and rigidity...
February 1, 2017: Journal of Colloid and Interface Science
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