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https://www.readbyqxmd.com/read/29668068/epidemiology-risk-factors-and-outcomes-of-invasive-aspergillosis-in-solid-organ-transplant-recipients-in-the-swiss-transplant-cohort-study
#1
D Neofytos, O Chatzis, D Nasioudis, E Boely Janke, T Doco Lecompte, C Garzoni, C Berger, A Cussini, K Boggian, N Khanna, O Manuel, N J Mueller, C van Delden
BACKGROUND: There is lack of recent multicenter epidemiological data on invasive aspergillosis (IA) among solid organ transplant recipient (SOTr) in the mold-acting antifungal era. We describe the epidemiology and outcomes of IA in a contemporary cohort of SOTr using the Swiss Transplant Cohort Study. METHODS: All consecutive SOTr with proven or probable IA between 01.05.2008 and 31.12.2014 were included. A case-control study to identify IA predictors was performed: 1-case was matched with 3-controls based on SOT type, transplant center, and time post-SOT...
April 18, 2018: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/29573643/profiles-of-internalizing-and-externalizing-symptoms-associated-with-bullying-victimization
#2
Meridith Eastman, Vangie Foshee, Susan Ennett, Daniela Sotres-Alvarez, H Luz McNaughton Reyes, Robert Faris, Kari North
This study identified profiles of internalizing (anxiety and depression) and externalizing (delinquency and violence against peers) symptoms among bullying victims and examined associations between bullying victimization characteristics and profile membership. The sample consisted of 1196 bullying victims in grades 8-10 (Mage  = 14.4, SD = 1.01) who participated in The Context Study in three North Carolina counties in Fall 2003. Five profiles were identified using latent profile analysis: an asymptomatic profile and four profiles capturing combinations of internalizing and externalizing symptoms...
March 21, 2018: Journal of Adolescence
https://www.readbyqxmd.com/read/29557910/solid-organ-transplantation-in-patients-with-preexisting-malignancies-in-remission-a-propensity-score-matched-cohort-study
#3
Sergio A Acuna, Rinku Sutradhar, S Joseph Kim, Nancy N Baxter
BACKGROUND: Solid organ transplant recipients (SOTR) with pretransplant malignancies (PTM) have worse overall survival (OS) compared to recipients without history of malignancy. However, it is unknown whether the increased risk of mortality is due to recurrent cancer-related deaths. METHODS: All SOTR in Ontario between 1991 and 2010 were identified and matched 1:2 to recipients without PTM using a propensity score. OS was compared using the Kaplan-Meier estimator and Cox proportional hazard models...
March 20, 2018: Transplantation
https://www.readbyqxmd.com/read/29548689/the-association-of-cardiorespiratory-fitness-with-cardiometabolic-factors-markers-of-inflammation-and-endothelial-dysfunction-in-latino-youth-findings-from-the-hispanic-community-children-s-health-study-study-of-latino-youth
#4
Carmen R Isasi, Garrett M Strizich, Robert Kaplan, Martha L Daviglus, Daniela Sotres-Alvarez, Denise C Vidot, Maria M Llabre, Gregory Talavera, Mercedes R Carnethon
PURPOSE: To evaluate the relationship of cardiorespiratory fitness (CRF) with cardiovascular disease risk factors and a biomarker of endothelial dysfunction (e-selectin) among Hispanic/Latino youth. METHODS: The study included 1380 Hispanic/Latino youths (8-16 years old) from the Hispanic Community Children's Health Study/Study of Latino Youth that enrolled from four cities (Bronx, Chicago, Miami, and San Diego). CRF was assessed by a 3-minute step test that uses postexercise heart rate to estimate maximal oxygen uptake...
February 15, 2018: Annals of Epidemiology
https://www.readbyqxmd.com/read/29546313/frequency-of-intake-and-type-of-away-from-home-foods-consumed-are-associated-with-diet-quality-in-the-hispanic-community-health-study-study-of-latinos-hchs-sol
#5
Amanda C McClain, Guadalupe X Ayala, Daniela Sotres-Alvarez, Anna Maria Siega-Riz, Robert C Kaplan, Marc D Gellman, Linda C Gallo, Linda Van Horn, Martha L Daviglus, Marisa J Perera, Josiemer Mattei
Background: Away-from-home foods (AFHFs) influence diet quality, a modifiable obesity risk factor, with limited generalizable evidence in Hispanic/Latino adults. Objective: We investigated associations between AFHF intake with diet quality and overweight or obesity among US Hispanic/Latino adults. Methods: Cross-sectional baseline (2008-2011) analyses included adults (n = 16,045) aged 18-74 y in the national Hispanic Community Health Study/Study of Latinos...
March 1, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29524280/redesign-of-laobp-to-bind-novel-l-amino-acid-ligands
#6
Jesús Banda-Vázquez, Sooruban Shanmugaratnam, Rogelio Rodríguez-Sotres, Alfredo Torres-Larios, Birte Höcker, Alejandro Sosa-Peinado
Computational protein design is still a challenge for advancing structure-function relationships. While recent advances in this field are promising, more information for genuine predictions is needed. Here, we discuss different approaches applied to install novel glutamine (Gln) binding into the Lysine/Arginine/Ornithine binding protein (LAOBP) from Salmonella typhimurium. We studied the ligand binding behaviour of two mutants: a binding pocket grafting design based on a structural superposition of LAOBP to the Gln binding protein QBP from Escherichia coli and a design based on statistical coupled positions...
March 10, 2018: Protein Science: a Publication of the Protein Society
https://www.readbyqxmd.com/read/29517497/residual-squamous-cell-carcinoma-after-shave-biopsy-in-solid-organ-transplant-recipients
#7
Muneeb Ilyas, Nan Zhang, Amit Sharma
BACKGROUND: After histopathological confirmation of a biopsy sample, cutaneous squamous cell carcinoma (cSCC) is often treated surgically; yet, residual tumor within the excision sample is not always found. The prevalence of residual cSCC after shave biopsy in solid organ transplant recipients (SOTRs) is unknown. OBJECTIVE: Determine the prevalence of residual cSCC after shave biopsy in SOTRs. METHODS: A retrospective case-controlled review was performed from a single center...
March 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29458516/chronic-disease-risk-typologies-among-young-adults-in-community-college
#8
Jayne K Jeffries, Leslie Lytle, Daniela Sotres-Alvarez, Shelley Golden, Allison E Aiello, Laura Linnan
OBJECTIVES: To address chronic disease risk holistically from a behavioral perspective, insights are needed to refine understanding of the covariance of key health behaviors. This study aims to identify distinct typologies of young adults based on 4 modifiable risk factors of chronic disease using a latent class analysis approach, and to describe patterns of class membership based on demographic characteristics, living arrangements, and weight. METHODS: Overall, 441 young adults aged 18-35 attending community colleges in the Minnesota Twin Cities area completed a baseline questionnaire for the Choosing Healthy Options in College Environments and Settings study, a RCT...
March 1, 2018: American Journal of Health Behavior
https://www.readbyqxmd.com/read/29449952/variations-of-dietary-intake-by-glycemic-status-and-hispanic-latino-heritage-in-the-hispanic-community-health-study-study-of-latinos-hchs-sol
#9
Sarah S Casagrande, Daniela Sotres-Alvarez, Larissa Avilés-Santa, Matthew J O'Brien, Cristina Palacios, Cynthia M Pérez, Samantha A Reina, Xueyin Wang, Qibin Qi, Aida L Giachello, Rebeca A Espinoza Giacinto, Catherine C Cowie
Objective: A healthy diet is important for diabetes prevention and control; however, few studies have assessed dietary intake among US Hispanics/Latinos, a diverse population with a significant burden of diabetes. To address this gap in the literature, we determined intake of energy, macro/micronutrients, and vitamin supplements among Hispanics/Latinos by glycemic status and heritage. Research design and methods: Cross-sectional study of adults aged 18-74 years from the Hispanic Community Health Study/Study of Latinos (2008-2011) with complete baseline data on glycemic status and two 24-hour dietary recalls (n=13 089)...
2018: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/29362089/review-pyrophosphate-and-pyrophosphatases-in-plants-their-involvement-in-stress-responses-and-their-possible-relationship-to-secondary-metabolism
#10
REVIEW
Francisca Morayna Gutiérrez-Luna, Eric Edmundo Hernández-Domínguez, Lilián Gabriela Valencia-Turcotte, Rogelio Rodríguez-Sotres
Pyrophosphate (PPi) is produced as byproduct of biosynthesis in the cytoplasm, nucleus, mitochondria and chloroplast, or in the tonoplast and Golgi by membrane-bound H+ -pumping pyrophosphatases (PPv). Inorganic pyrophosphatases (E.C. 3.6.1.1; GO:0004427) impulse various biosynthetic reactions by recycling PPi and are essential to living cells. Soluble and membrane-bound enzymes of high specificity have evolved in different protein families and multiple pyrophosphatases are encoded in all plant genomes known to date...
February 2018: Plant Science: An International Journal of Experimental Plant Biology
https://www.readbyqxmd.com/read/29338957/commuting-and-sleep-results-from-the-hispanic-community-health-study-study-of-latinos-sue%C3%A3-o-ancillary-study
#11
Megan E Petrov, Jia Weng, Kathryn J Reid, Rui Wang, Alberto R Ramos, Douglas M Wallace, Carmela Alcantara, Jianwen Cai, Krista Perreira, Rebeca A Espinoza Giacinto, Phyllis C Zee, Daniela Sotres-Alvarez, Sanjay R Patel
INTRODUCTION: Commute time is associated with reduced sleep time, but previous studies have relied on self-reported sleep assessment. The present study investigated the relationships between commute time for employment and objective sleep patterns among non-shift working U.S. Hispanic/Latino adults. METHODS: From 2010 to 2013, Hispanic/Latino employed, non-shift-working adults (n=760, aged 18-64 years) from the Sueño study, ancillary to the Hispanic Community Health Study/Study of Latinos, reported their total daily commute time to and from work, completed questionnaires on sleep and other health behaviors, and wore wrist actigraphs to record sleep duration, continuity, and variability for 1 week...
March 2018: American Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29331726/impact-of-the-start-up-process-on-the-microbial-communities-in-biocathodes-for-electrosynthesis
#12
Raúl Mateos, Ana Sotres, Raúl M Alonso, Adrián Escapa, Antonio Morán
This study seeks to understand how the bacterial communities that develop on biocathodes are influenced by inocula diversity and electrode potential during start-up. Two different inocula are used: one from a highly diverse environment (river mud) and the other from a low diverse milieu (anaerobic digestion). In addition, both inocula were subjected to two different polarising voltages: oxidative (+0.2 V vs. Ag/AgCl) and reductive (-0.8 V vs. Ag/AgCl). Bacterial communities were analysed by means of high throughput sequencing...
June 2018: Bioelectrochemistry
https://www.readbyqxmd.com/read/29318759/associations-of-sodium-and-potassium-with-obesity-measures-among-diverse-us-hispanic-latino-adults-results-from-the-hispanic-community-health-study-study-of-latinos
#13
Tali Elfassy, Yasmin Mossavar-Rahmani, Linda Van Horn, Marc Gellman, Daniela Sotres-Alvarez, Neil Schneiderman, Martha Daviglus, Jeannette M Beasley, Maria M Llabre, Pamela A Shaw, Guillermo Prado, Hermes Florez, Adina Zeki Al Hazzouri
OBJECTIVE: The objective of this study was to evaluate cross-sectional associations of sodium and potassium with BMI, waist circumference (WC), and body fat and to determine whether the nativity and/or duration of United States (US) residence modified these associations. METHODS: Sodium and potassium were derived from 24-hour diet recalls from 16,156 US participants of the 2008 to 2011 Hispanic Community Health Study/Study of Latinos (HCHS/SOL) and from 24-hour urine in 447 HCHS/SOL participants...
February 2018: Obesity
https://www.readbyqxmd.com/read/29316554/skin-infections-due-to-bacteria-in-solid-organ-transplant-recipients-a-review
#14
Muneeb Ilyas, Nishita Maganty, Zachary Ginsberg, Amit Sharma
Though there is an abundance of information on cutaneous malignancies in transplant recipients, cutaneous infections in solid organ transplant recipients (SOTRs) are underrepresented in the dermatological literature. Our paper provides a comprehensive review of bacterial cutaneous infections within the solid organ transplant population. Cutaneous bacterial infections may lead to significant morbidity and even mortality in this immunosuppressed population. Thus, it is to the benefit of both dermatologists and other transplant care providers to better understand and recognize the features of cutaneous bacterial infections in SOTRs...
2017: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/29284295/perceptions-of-cancer-risk-efficacy-and-cancer-related-risk-behaviors-results-from-the-hchs-sol-sociocultural-ancillary-study
#15
Rina S Fox, Sarah D Mills, Scott C Roesch, Daniela Sotres-Alvarez, Patricia Gonzalez, Venera Bekteshi, Jianwen Cai, David W Lounsbury, Gregory A Talavera, Frank J Penedo, Vanessa L Malcarne
This study evaluated the associations among perceived risk, perceived efficacy, and engagement in six cancer-related risk behaviors in a population-based Hispanic/Latino sample. Interviews were conducted with 5,313 Hispanic/Latino adults as part of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL) Sociocultural Ancillary Study. Participants were recruited from the study's four field centers (Bronx, NY; Chicago, IL; Miami, FL; San Diego, CA) between February 2010 and June 2011. Perceived risk and perceived efficacy were assessed with questions drawn from the Health Interview National Trends Survey...
December 1, 2017: Health Education & Behavior: the Official Publication of the Society for Public Health Education
https://www.readbyqxmd.com/read/29281051/evaluation-of-a-novel-global-immunity-assay-to-predict-infection-in-organ-transplant-recipients
#16
Muhtashim Mian, Yoichiro Natori, Victor Ferreira, Nazia Selzner, Shahid Husain, Lianne Singer, S Joseph Kim, Atul Humar, Deepali Kumar
Background: Solid organ transplant recipients (SOTRs) are predisposed to infection due to the need for lifelong immunosuppression, although tools to measure the overall degree of immunosuppression are limited. In this study, we used a novel global cell-mediated immunity (CMI) assay to quantify the degree of immunosuppression and predict subsequent infections. Methods: Consecutive SOTRs were enrolled and provided whole blood to conduct the global CMI assay (QuantiFERON Monitor) at 1, 3, and 6 months posttransplant...
December 21, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29167858/cutaneous-squamous-cell-carcinomas-in-solid-organ-transplant-recipients-compared-with-immunocompetent-patients
#17
Joyce Y Cheng, Fang-Yong Li, Christine J Ko, Oscar R Colegio
Importance: Solid organ transplant recipients (SOTRs) have a 100-fold increased risk of squamous cell carcinoma (SCC), and they may develop more aggressive SCCs compared with immunocompetent individuals. Objective: To compare outcomes associated with aggressive behavior of SCC in SOTRs and high-risk immunocompetent patients. Design, Setting, and Participants: A retrospective cohort study of 58 SOTRs and 40 immunocompetent patients evaluated at the Yale Transplant Dermatology Clinic in New Haven, Connecticut, who had at least 1 SCC confirmed histopathologically between January 1, 2008, and December 31, 2015...
January 1, 2018: JAMA Dermatology
https://www.readbyqxmd.com/read/29159658/lung-necrosectomy-in-pediatric-patients-with-necrotizing-pneumonia
#18
Francina V Bolaños-Morales, Emmanuel Peña Gómez-Portugal, María E Aguilar-Mena, Patricio J Santillán-Doherty, Avelina Sotres-Vega, J Alfredo Santibáñez-Salgado
INTRODUCTION: Necrotizing pneumonia is the consolidation of lung parenchyma with destruction and necrosis, forming solitary or multiloculated radiolucent foci. When antibiotic treatment fails and clinical course does not improve, patients might need lung tissue resection: segmentectomy, lobectomy or bilobectomy. We have performed a more conservative surgical approach in pediatric patients with necrotizing pneumonia, lung necrosectomy: resection of unviable necrotic tissue, to preserve more healthy and potentially recoverable lung parenchyma...
November 20, 2017: General Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29115297/applying-recovery-biomarkers-to-calibrate-self-report-measures-of-sodium-and-potassium-in-the-hispanic-community-health-study-study-of-latinos
#19
Y Mossavar-Rahmani, D Sotres-Alvarez, W W Wong, C M Loria, M D Gellman, L Van Horn, M H Alderman, J M Beasley, C M Lora, A M Siega-Riz, R C Kaplan, P A Shaw
This corrects the article DOI: 10.1038/jhh.2016.98.
December 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/29062127/graphene-oxide-electrodeposited-electrode-enhances-start-up-and-selective-enrichment-of-exoelectrogens-in-bioelectrochemical-systems
#20
R M Alonso, M I San-Martín, A Sotres, A Escapa
This study seeks to assess the impact that the anodic electrodeposition of graphene oxide (GO) has on the start-up process and on the development of microbial communities on the anode of BESs. The GO electrodeposited electrodes were characterised in abiotic conditions to verify the extent of the modification and were then transferred to a bioelectrochemical reactor. Results showed that the modified electrode allowed for a reduced start-up time compared to the control electrode. After three months, high throughput sequencing was performed, revealing that electrochemically reduced graphene oxide acts as a selective agent toward exoelectrogenic bacteria as Geobacter...
October 23, 2017: Scientific Reports
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