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https://www.readbyqxmd.com/read/28818366/expression-of-recombinant-snrk1-in-e-coli-characterization-of-adenine-nucleotide-binding-to-the-snrk1-1-akin%C3%AE-%C3%AE-%C3%AE-3-complex
#1
José Luis Maya-Bernal, Alejandra Ávila, Ana Ruiz-Gayosso, Ricardo Trejo-Fregoso, Nancy Pulido, Alejandro Sosa-Peinado, Esther Zúñiga-Sánchez, Eleazar Martínez-Barajas, Rogelio Rodríguez-Sotres, Patricia Coello
The SnRK1 complexes in plants belong to the family of AMPK/SNF1 kinases, which have been associated with the control of energy balance, in addition to being involved in the regulation of other aspects of plant growth and development. Analysis of complex formation indicates that increased activity is achieved when the catalytic subunit is phosphorylated and bound to regulatory subunits. SnRK1.1 subunit activity is higher than that of SnRK1.2, which also exhibits reduced activation due to the regulatory subunits...
October 2017: Plant Science: An International Journal of Experimental Plant Biology
https://www.readbyqxmd.com/read/28767517/accuracy-of-self-reported-weight-in-hispanic-latino-adults-of-the-hispanic-community-health-study-study-of-latinos-hchs-sol
#2
Lindsay Fernández-Rhodes, Whitney R Robinson, Daniela Sotres-Alvarez, Nora Franceschini, Sheila F Castañeda, Christina Buelna, Ashley Moncrieft, Maria Llabre, Martha L Daviglus, Qibin Qi, Anita Agarwal, Carmen R Isasi, Paul Smokowski, Penny Gordon-Larsen, Kari E North
BACKGROUND: Previous United States (U.S.) population-based studies have found that body weight may be underestimated when self-reported. However, this research may not apply to all U.S. Hispanics/Latinos, many of whom are immigrants with distinct cultural orientations to ideal body size. We assessed the data quality and accuracy of self-reported weight in a diverse, community-based, U.S. sample of primarily foreign-born Hispanic/Latino adults. METHODS: Using baseline data (2008-2011) from the Hispanic Community Health Study/Study of Latinos (HCHS/SOL), we described the difference between contemporaneous self-reported and measured current body weight (n=16,119) and used multivariate adjusted models to establish whether the observed trends in misreporting in potential predictors of inaccuracy persisted after adjustment for other predictors...
July 31, 2017: Epidemiology
https://www.readbyqxmd.com/read/28765082/is-there-a-relationship-between-accelerometer-assessed-physical-activity-and-sedentary-behavior-and-cognitive-function-in-us-hispanic-latino-adults-the-hispanic-community-health-study-study-of-latinos-hchs-sol
#3
Elizabeth Vásquez, Garrett Strizich, Carmen R Isasi, Sandra E Echeverria, Daniela Sotres-Alvarez, Kelly R Evenson, Marc D Gellman, Priya Palta, Qibin Qi, Melissa Lamar, Wassim Tarraf, Hector M González, Robert Kaplan
Normative changes in cognitive function are expected with increasing age. Research on the relationship between normative cognitive decline and moderate-to-vigorous physical activity (MVPA) and sedentary behavior (SED) needs further investigation in Hispanic/Latinos adults. We assessed the cross-sectional association between accelerometer assessed MVPA and SED with cognitive function in 7,478 adults aged 45-74years from the Hispanic Community Health Study/Study of Latinos. At baseline, cognitive tests included two executive function tests (Digit Symbol Substitution Test (DSST), a test of language (Word Fluency), and a test of memory (Spanish English Verbal Learning Test)...
July 29, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28761660/association-of-the-dash-dietary-pattern-with-insulin-resistance-and-diabetes-in-us-hispanic-latino-adults-results-from-the-hispanic-community-health-study-study-of-latinos-hchs-sol
#4
Leonor Corsino, Daniela Sotres-Alvarez, Nicole M Butera, Anna María Siega-Riz, Cristina Palacios, Cynthia M Pérez, Sandra S Albrecht, Rebecca A Espinoza Giacinto, Marisa Judith Perera, Linda Van Horn, M Larissa Avilés-Santa
OBJECTIVE: To examine the association between diet quality and both diabetes status and insulin resistance in Hispanic/Latino adults, and the extent to which differences in diet quality contribute to differences in outcomes across Hispanic/Latino heritage. RESEARCH DESIGN AND METHODS: Cross-sectional study. Data are from 15 942 individuals enrolled in the Hispanic Community Health Study/Study of Latinos. Diet was ascertained using two 24-hour dietary recalls, and diet quality was measured using the Dietary Approaches to Stop Hypertension (DASH) score (range: 0-80, lowest to highest)...
2017: BMJ Open Diabetes Research & Care
https://www.readbyqxmd.com/read/28736001/evaluating-retention-of-skin-cancer-education-in-kidney-transplant-recipients-reveals-a-window-of-opportunity-for-re-education
#5
P H Patel, K Bibee, G Lim, S M Malik, C Wu, M Pugliano-Mauro
BACKGROUND: Skin cancer is the most common malignancy after solid organ transplant and can lead to significant morbidity. The likelihood of developing squamous cell carcinomas and melanomas is 100 and 2.4 times more likely, respectively, in kidney transplant recipients when compared with the general population. There are few data regarding the assessment and influence of solid organ transplant recipient (SOTR) knowledge of skin cancer and its effect on short- and long-term awareness and behavior...
July 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28666597/diet-quality-inflammation-and-the-ankle-brachial-index-in-adults-with-or-without-cardiometabolic-conditions
#6
Josiemer Mattei, Daniela Sotres-Alvarez, Marc Gellman, Sheila F Castañeda, Frank B Hu, Katherine L Tucker, Anna Maria Siega-Riz, Robert C Kaplan
BACKGROUND & AIMS: Diet quality may influence non-traditional cardiovascular disease (CVD) risk factors - namely, C-reactive protein (CRP) and the ankle-brachial index (ABI). Pre-existing traditional cardiometabolic conditions may confound this association. We aimed to determine whether diet quality was associated with high-risk CRP or ABI, independently from traditional cardiometabolic risk factors. METHODS: Baseline data were analyzed from US-Hispanics/Latinos aged 18-74 y without previously-diagnosed CVD participating in the population-based Hispanic Community Health Study/Study of Latinos cohort...
June 8, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28546455/objectively-measured-sedentary-time-and-cardiovascular-risk-factor-control-in-us-hispanics-latinos-with-diabetes-mellitus-results-from-the-hispanic-community-health-study-study-of-latinos-hchs-sol
#7
Xueyin Wang, Garrett Strizich, Simin Hua, Daniela Sotres-Alvarez, Christina Buelna, Linda C Gallo, Marc D Gellman, Yasmin Mossavar-Rahmani, Matthew J O'Brien, Mark Stoutenberg, Tao Wang, M Larissa Avilés-Santa, Robert C Kaplan, Qibin Qi
BACKGROUND: Cardiovascular disease (CVD) risk factor control is a cornerstone of diabetes mellitus management. Little is known about relationships of objectively measured sedentary time and physical activity with major CVD risk factor control in individuals with diabetes mellitus. We examined associations of objectively measured sedentary time and moderate-to-vigorous physical activity with reaching major CVD risk factor control goals among US Hispanic/Latino adults with diabetes mellitus...
May 25, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28485086/uptake-of-cancer-screening-tests-among-recipients-of-solid-organ-transplantation
#8
S A Acuna, R Sutradhar, X Camacho, C Daly, M E Del Giudice, S J Kim, N N Baxter
Population-based cancer screening recommendations are also suggested for solid organ transplant recipients (SOTR); however, recommendation adherence is unknown. In a population-based cohort of SOTR in Ontario between 1997 and 2010, we determined the uptake of breast, cervical, and colorectal cancer screening tests and identified factors associated with up-to-date screening using recurrent event analysis. We identified 4436 SOTR eligible for colorectal, 2252 for cervical, and 1551 for breast cancer screening...
May 9, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28452165/cutaneous-toxicities-from-transplant-related-medications
#9
M Ilyas, O R Colegio, B Kaplan, A Sharma
Despite the abundance of information on cutaneous malignancies associated with solid organ transplantation in the transplant literature, there is limited information regarding non-malignant skin changes after transplantation. There are numerous skin toxicities secondary to immunosuppressive and other transplant-related medications that can vary in presentation, severity, and prognosis. In order to limit associated morbidity and mortality, SOTR care providers should effectively identify and manage cutaneous manifestations secondary to drug toxicity...
April 27, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28425766/update-in-the-treatment-of-non-influenza-respiratory-virus-infection-in-solid-organ-transplant-recipients
#10
Shellee A Grim, Gail E Reid, Nina M Clark
Despite the improved outcomes in solid organ transplantation with regard to prevention of rejection and increased patient and graft survival, infection remains a common cause of morbidity and mortality. Respiratory viruses are a frequent and potentially serious cause of infection after solid organ transplantation. Furthermore, clinical manifestations of respiratory virus infection (RVI) may be more severe and unusual in solid organ transplant recipients (SOTRs) compared with the non-immunocompromised population...
June 2017: Expert Opinion on Pharmacotherapy
https://www.readbyqxmd.com/read/28422609/isotemporal-analysis-of-the-association-of-objectively-measured-physical-activity-with-depressive-symptoms-results-from-hispanic-community-health-study-study-of-latinos-hchs-sol
#11
Chad D Rethorst, Ashley E Moncrieft, Marc D Gellman, Elva M Arredondo, Christina Buelna, Shelia F Castañeda, Martha L Daviglus, Unab I Khan, Krista M Perreira, Daniela Sotres-Alvarez, Mark Stoutenberg
BACKGROUND: The burden of depression among Hispanics/Latinos indicates the need to identify factors related to depressive symptoms. This paper examines the relationship of physical activity (PA) and sedentary behavior (SB) with depressive symptoms in Hispanic/Latinos. METHODS: The Hispanic Community Health Study / Study of Latinos (HCHS/SOL) is a population-based, cohort study of Hispanic/Latinos in four United States metropolitan areas. Objectively measured PA was coded into: sedentary behavior (SB), light-intensity (LPA), moderate-intensity (MPA), and vigorous-intensity (VPA); and the Center for Epidemiological Studies Depression Scale-10 assessed depressive symptoms...
April 19, 2017: Journal of Physical Activity & Health
https://www.readbyqxmd.com/read/28407149/determination-of-the-biological-form-of-human-cytomegalovirus-dna-in-the-plasma-of-solid-organ-transplant-recipients
#12
Yupin Tong, Xiaoli L Pang, Curtis Mabilangan, Jutta K Preiksaitis
Background: Whether cytomegalovirus (CMV) DNA exists in plasma as virion-associated or free DNA is uncertain. Methods: An assay combining DNase I digestion and CMV quantitative polymerase chain reaction (DNase-CMV-qPCR) was developed to differentiate free naked DNA from virion DNA. One hundred three frozen and 10 fresh CMV DNA-positive plasma samples from solid-organ transplant recipients (SOTRs) were tested. Three sets of paired qPCR (P-qPCR) assays with amplicons of variable length were used to study CMV DNA fragmentation in 20 SOTR plasma samples, viral stocks (Towne, Merlin, AD169) and the first World Health Organization (WHO) international standard (IS) for CMV DNA...
April 1, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28398853/the-association-of-parental-caregiver-chronic-stress-with-youth-obesity-findings-from-the-study-of-latino-youth-and-the-hispanic-community-health-study-study-of-latinos-sociocultural-ancillary-study
#13
Carmen R Isasi, Simin Hua, Molly Jung, Mercedes R Carnethon, Krista Perreira, Denise C Vidot, Christian R Salazar, Jessica L McCurley, Daniela Sotres-Alvarez, Linda Van Horn, Alan M Delamater, Maria M Llabre, Linda C Gallo
BACKGROUND: Prior studies indicate that chronic stress is associated with obesity in adults. However, whether parental/caregiver stress is associated with obesity in their offspring has not been widely examined in Hispanic/Latino populations. In this study, we evaluated the role of caregiver chronic stress on child obesity and whether home food environment or child lifestyle behaviors explained the association. METHODS: The study included a sample of Hispanic/Latino youth and their caregivers (n = 473) from the Study of Latinos (SOL) Youth study and the Hispanic Community Health Study/SOL Sociocultural Study, which enrolled children aged 8-16 years from four cities (Bronx, Chicago, Miami, and San Diego), and provided assessments of adult chronic stress...
August 2017: Childhood Obesity
https://www.readbyqxmd.com/read/28364514/actigraphic-sleep-patterns-of-u-s-hispanics-the-hispanic-community-health-study-study-of-latinos
#14
Katherine A Dudley, Jia Weng, Daniela Sotres-Alvarez, Guido Simonelli, Elizabeth Cespedes Feliciano, Maricelle Ramirez, Alberto R Ramos, Jose S Loredo, Kathryn J Reid, Yasmin Mossavar-Rahmani, Phyllis C Zee, Diana A Chirinos, Linda C Gallo, Rui Wang, Sanjay R Patel
Study objective: To assess the extent to which objective sleep patterns vary among U.S. Hispanics/Latinos. Methods: We assessed objective sleep patterns in 2087 participants of the Hispanic Community Health Study/Study of Latinos from 6 Hispanic/Latino subgroups aged 18-64 years who underwent 7 days of wrist actigraphy. Results: The age- and sex-standardized mean (SE) sleep duration was 6.82 (0.05), 6.72 (0.07), 6.61 (0.07), 6.59 (0.06), 6...
February 1, 2017: Sleep
https://www.readbyqxmd.com/read/28364454/neighborhood-factors-as-predictors-of-poor-sleep-in-the-sue%C3%A3-o-ancillary-study-of-the-hispanic-community-health-study-study-of-latinos
#15
Guido Simonelli, Katherine A Dudley, Jia Weng, Linda C Gallo, Krista Perreira, Neomi A Shah, Carmela Alcantara, Phyllis C Zee, Alberto R Ramos, Maria M Llabre, Daniela Sotres-Alvarez, Rui Wang, Sanjay R Patel
Study Objectives: To evaluate whether an adverse neighborhood environment has higher prevalence of poor sleep in a US Hispanic/Latino population. Methods: A cross-sectional analysis was performed in 2156 US Hispanic/Latino participants aged 18-64 years from the Sueño ancillary study of the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Participants completed surveys of neighborhood environment including perceived safety, violence and noise, the Insomnia Severity Index (ISI), and 7 days of wrist actigraphy...
January 1, 2017: Sleep
https://www.readbyqxmd.com/read/28362949/two-doses-of-inactivated-influenza-vaccine-improve-immune-response-in-solid-organ-transplant-recipients-results-of-transgripe-1-2-a-randomized-controlled-clinical-trial
#16
Elisa Cordero, Cristina Roca-Oporto, Angel Bulnes-Ramos, Teresa Aydillo, Joan Gavaldà, Asunción Moreno, Julián Torre-Cisneros, Jose Miguel Montejo, Jesús Fortun, Patricia Muñoz, Nuria Sabé, Maria Carmen Fariñas, Marino Blanes-Julia, Francisco López-Medrano, Alejandro Suárez-Benjumea, Juliana Martinez-Atienza, Clara Rosso-Fernández, Pilar Pérez-Romero
Background: Influenza vaccine effectiveness is not optimal in solid organ transplant recipients (SOTR). We hypothesized that a booster dose might increase it. Methods: TRANSGRIPE 1-2 is a phase 3, randomized, controlled, multicenter, open-label clinical trial. Patients were randomly assigned (1:1 stratified by study site, type of organ, and time since transplantation) to receive 1 dose (control group) or 2 doses (booster group) of the influenza vaccine 5 weeks apart...
April 1, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/28349622/actigraphic-sleep-measures-and-diet-quality-in-the-hispanic-community-health-study-study-of-latinos-sue%C3%A3-o-ancillary-study
#17
Yasmin Mossavar-Rahmani, Jia Weng, Rui Wang, Pamela A Shaw, Molly Jung, Daniela Sotres-Alvarez, Sheila F Castañeda, Linda C Gallo, Marc D Gellman, Qibin Qi, Alberto R Ramos, Kathryn J Reid, Linda Van Horn, Sanjay R Patel
Using a cross-sectional probability sample with actigraphy data and two 24-h dietary recalls, we quantified the association between sleep duration, continuity, variability and timing with the Alternative Healthy Eating Index-2010 diet quality score and its components in 2140 Hispanic Community Health Study/Study of Latinos participants. The Alternative Healthy Eating Index diet quality-2010 score ranges from 0 to 110, with higher scores indicating greater adherence to the dietary guidelines and lower risk from major chronic disease...
March 28, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28347359/the-association-of-trajectories-of-protein-intake-and-age-specific-protein-intakes-from-2-to-22-years-with-bmi-in-early-adulthood
#18
Melecia Wright, Daniela Sotres-Alvarez, Michelle A Mendez, Linda Adair
No study has analysed how protein intake from early childhood to young adulthood relate to adult BMI in a single cohort. To estimate the association of protein intake at 2, 11, 15, 19 and 22 years with age- and sex-standardised BMI at 22 years (early adulthood), we used linear regression models with dietary and anthropometric data from a Filipino birth cohort (1985-2005, n 2586). We used latent growth curve analysis to identify trajectories of protein intake relative to age-specific recommended daily allowance (intake in g/kg body weight) from 2 to 22 years, then related trajectory membership to early adulthood BMI using linear regression models...
March 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28205551/applying-recovery-biomarkers-to-calibrate-self-report-measures-of-sodium-and-potassium-in-the-hispanic-community-health-study-study-of-latinos
#19
Y Mossavar-Rahmani, D Sotres-Alvarez, W W Wong, C M Loria, M D Gellman, L Van Horn, M H Alderman, J M Beasley, C M Lora, A M Siega-Riz, R C Kaplan, P A Shaw
Measurement error in assessment of sodium and potassium intake obscures associations with health outcomes. The level of this error in a diverse US Hispanic/Latino population is unknown. We investigated the measurement error in self-reported dietary intake of sodium and potassium and examined differences by background (Central American, Cuban, Dominican, Mexican, Puerto Rican and South American). In 2010-2012, we studied 447 participants aged 18-74 years from four communities (Miami, Bronx, Chicago and San Diego), obtaining objective 24-h urinary sodium and potassium excretion measures...
July 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/28202188/rate-of-regional-nodal-metastases-of-cutaneous-squamous-cell-carcinoma-in-the-immunosuppressed-patient
#20
Eamon J McLaughlin, Lauren Miller, Thuzar M Shin, Joseph F Sobanko, Steven B Cannady, Christopher J Miller, Jason G Newman
PURPOSE: Immunosuppressed solid organ transplant recipients (SOTRs) have an increased risk of developing cutaneous squamous cell carcinomas (cSCCs) with metastatic potential. This study sought to determine the rate of regional lymph node involvement in a large cohort of solid organ transplant patients with cutaneous head and neck squamous cell carcinoma. MATERIALS AND METHODS: A retrospective chart review was performed on solid organ transplant patients with head and neck cutaneous squamous cell carcinoma treated at a tertiary academic medical center from 2005 to 2015...
May 2017: American Journal of Otolaryngology
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