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https://www.readbyqxmd.com/read/28207060/do-national-drug-policies-influence-antiretroviral-drug-prices-evidence-from-the-southern-african-development-community
#1
Yao Liu, Omar Galárraga
No abstract text is available yet for this article.
March 1, 2017: Health Policy and Planning
https://www.readbyqxmd.com/read/28185745/how-emergency-department-ed-admission-decisions-differ-when-the-same-physician-works-in-two-different-eds
#2
Jesse M Pines, Jessica E Galarraga, Michael Granvosky, Ori Litvak, Samuel Davis, Leah Honigman Warner
STUDY OBJECTIVE: Emergency physicians often work in multiple hospital emergency departments (EDs). We study how emergency physician admission decisions vary in different settings. METHODS: We conducted a retrospective, cross-sectional study over two years (2012-3) in six EDs in three states. Included physicians had ≥200 encounters per site in two different EDs. "Admissions" were ED encounters resulting in admission to the hospital or transfer to another hospital...
February 2, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28110864/sexual-behavior-among-orphaned-adolescents-in-western-kenya-a-comparison-of-institutional-and-family-based-care-settings
#3
Lonnie Embleton, Joram Nyandat, David Ayuku, Edwin Sang, Allan Kamanda, Samuel Ayaya, Winstone Nyandiko, Peter Gisore, Rachel Vreeman, Lukoye Atwoli, Omar Galarraga, Mary A Ott, Paula Braitstein
PURPOSE: This study sought to assess whether risky sexual behaviors and sexual exploitation of orphaned adolescents differed between family-based and institutional care environments in Uasin Gishu County, Kenya. METHODS: We analyzed baseline data from a cohort of orphaned adolescents aged 10-18 years living in 300 randomly selected households and 19 charitable children's institutions. The primary outcomes were having ever had consensual sex, number of sex partners, transactional sex, and forced sex...
January 16, 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/28069845/at-federally-funded-health-centers-medicaid-expansion-was-associated-with-improved-quality-of-care
#4
Megan B Cole, Omar Galárraga, Ira B Wilson, Brad Wright, Amal N Trivedi
In 2014 many uninsured, low-income nonelderly adults gained access to health insurance in states that expanded Medicaid eligibility under the Affordable Care Act. Federally funded community health centers were likely to be particularly affected by this expansion because many of their patients were uninsured and low income. We used a difference-in-differences approach to compare changes among 1,057 such centers in expansion versus nonexpansion states from 2011 to 2014, in terms of their patients' insurance coverage, the number of patients they served, and the quality of care they provided...
January 1, 2017: Health Affairs
https://www.readbyqxmd.com/read/27974611/activation-of-glutamatergic-fibers-in-the-anterior-nac-shell-modulates-reward-activity-in-the-anacsh-the-lateral-hypothalamus-and-medial-prefrontal-cortex-and-transiently-stops-feeding
#5
Luis Prado, Jorge Luis-Islas, Osvaldo I Sandoval, Liliana Puron, Moreno M Gil, Alvaro Luna, Mario A Arias-García, Elvira Galarraga, Sidney A Simon, Ranier Gutierrez
: Although the release of mesoaccumbal dopamine is certainly involved in rewarding responses, recent studies point to the importance of the interaction between it and glutamate. One important component of this network is the anterior nucleus accumbens shell (aNAcSh), which sends GABAergic projections into the lateral hypothalamus (LH) and receives extensive glutamatergic inputs from, among others, the medial prefrontal cortex (mPFC). The effects of glutamatergic activation of aNAcSh on the ingestion of rewarding stimuli as well as its effect in the LH and mPFC are not well understood...
December 14, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27902652/circulating-antibody-1-and-2-years-after-vaccination-with-the-13-valent-pneumococcal-conjugate-vaccine-in-preterm-compared-with-term-infants
#6
Federico Martinón-Torres, Jacek Wysocki, Kimberly J Center, Hanna Czajka, Ewa Majda-Stanislawska, Felix Omeñaca, Ana Concheiro-Guisan, Francisco Gimenez-Sanchez, Leszek Szenborn, Daniel Blázquez-Gamero, Laura Moreno-Galarraga, Peter C Giardina, Gang Sun, William C Gruber, Daniel A Scott, Alejandra Gurtman
BACKGROUND: Premature infants have lower short-term immune responses to vaccination than term infants, but patterns of antibody persistence in preterm infants over longer periods are not well established. This study assessed the persistence of antibody response to the 13-valent pneumococcal conjugate vaccine (PCV13) in formerly preterm versus term infants. METHODS: In total, 100 preterm and 100 term infants received PCV13 with routine vaccines at ages 2, 3, 4 and 12 months...
March 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/27871017/predicting-postoperative-gait-in-cerebral-palsy
#7
Omar A Galarraga C, Vincent Vigneron, Bernadette Dorizzi, Néjib Khouri, Eric Desailly
In this work, postoperative lower limb kinematics are predicted with respect to preoperative kinematics, physical examination and surgery data. Data of 115 children with cerebral palsy that have undergone single-event multilevel surgery were considered. Preoperative data dimension was reduced utilizing principal component analysis. Then, multiple linear regressions with 80% confidence intervals were performed between postoperative kinematics and bilateral preoperative kinematics, 36 physical examination variables and combinations of 9 different surgical procedures...
November 9, 2016: Gait & Posture
https://www.readbyqxmd.com/read/27753679/costs-along-the-service-cascades-for-hiv-testing-and-counselling-and-prevention-of-mother-to-child-transmission
#8
Sergio Bautista-Arredondo, Sandra G Sosa-Rubí, Marjorie Opuni, David Contreras-Loya, Ada Kwan, Claire Chaumont, Abson Chompolola, Jeanine Condo, Omar Galárraga, Neil Martinson, Felix Masiye, Sabin Nsanzimana, Ivan Ochoa-Moreno, Richard Wamai, Joseph Wang'ombe
OBJECTIVE: We estimate facility-level average annual costs per client along the HIV testing and counselling (HTC) and prevention of mother-to-child transmission (PMTCT) service cascades. DESIGN: Data collected covered the period 2011-2012 in 230 HTC and 212 PMTCT facilities in Kenya, Rwanda, South Africa, and Zambia. METHODS: Input quantities and unit prices were collected, as were output data. Annual economic costs were estimated from the service providers' perspective using micro-costing...
October 23, 2016: AIDS
https://www.readbyqxmd.com/read/27750384/anti-biofilm-properties-of-bioactive-glasses-embedding-organic-active-compounds
#9
REVIEW
M E Galarraga-Vinueza, J Mesquita-Guimarães, R S Magini, J C M Souza, M C Fredel, A R Boccaccini
Bioactive glasses (BGs) are promising materials for bone repair due to their desirable properties such as osteoconductivity, biodegradability, angiogenic potential, and antibacterial activity. Ionic dissolution products from bioactive glasses increase the medium pH inhibiting surrounding bacteria proliferation. The activity of BGs against biofilm formation has been enhanced by incorporating organic antibacterial compounds. The aim of this review was to summarize evidence in literature which assesses the efficacy of antibacterial and anti-biofilm compounds embedded in bioactive glasses to prevent peri-implant infection during bone healing...
February 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/27591130/do-national-drug-policies-influence-antiretroviral-drug-prices-evidence-from-the-southern-african-development-community
#10
Yao Liu, Omar Galárraga
BACKGROUND: The efficacy of low- and middle-income countries' (LMIC) national drug policies in managing antiretroviral (ARV) pharmaceutical prices is not well understood. Though ARV drug prices have been declining in LMIC over the past decade, little research has been done on the role of their national drug policies. This study aims to (i) analyse global ARV prices from 2004 to 2013 and (ii) examine the relationship of national drug policies to ARV prices. METHODS: Analysis of ARV drug prices utilized data from the Global Price Reporting Mechanism from the World Health Organization (WHO)...
September 1, 2016: Health Policy and Planning
https://www.readbyqxmd.com/read/27580930/predictors-of-morbidity-and-cleavage-plane-in-surgical-resection-of-pure-convexity-meningiomas-using-cerebrospinal-fluid-sensitive-image-subtraction-magnetic-resonance-imaging
#11
José Luis Thenier-Villa, Raúl Alejandro Galárraga Campoverde, Adolfo Ramón DE LA Lama Zaragoza, Cesáreo Conde Alonso
Meningiomas are the most common primary intracranial tumors. Since the adhesions in the plane of dissection are of interest in surgical planning, we suggest that digital image subtraction of FLAIR data from the T2 sequence of MRI may represent better the CSF spaces in the brain-tumor interface and may be a predictor of the intraoperative cleavage plane. From 2006 to 2016, 83 convexity meningiomas were resected in the Department of Neurosurgery of the University Hospital Complex of Vigo, an analysis of preoperative MRI was performed to assess peritumoral edema (PTE), tumor volume, among others; a digital subtraction of T2-FLAIR sequences was performed and analyzed in relationship to the cleavage plane described in the intraoperative report and postoperative neurological deficits...
January 15, 2017: Neurologia Medico-chirurgica
https://www.readbyqxmd.com/read/27556485/association-between-body-mass-index-waist-to-height-ratio-and-adiposity-in-children-a-systematic-review-and-meta-analysis
#12
REVIEW
Nerea Martin-Calvo, Laura Moreno-Galarraga, Miguel Angel Martinez-Gonzalez
Obesity is defined as an abnormal or excessive fat accumulation that may impair health. Dual-energy X-ray absorptiometry (DEXA) has been suggested as the gold standard to define obesity, but because its use is complex and expensive, anthropometric measures such as body mass index (BMI) or the waist-to-height ratio (WtHr) have been used as alternatives. The aim of this study was to review the published literature and investigate the correlation of BMI and WtHr with body fat (BF) measured by DEXA in pediatric populations...
August 20, 2016: Nutrients
https://www.readbyqxmd.com/read/27492142/chronic-hepatitis-c-virus-hcv-burden-in-rhode-island-modelling-treatment-scale-up-and-elimination
#13
A I Soipe, H Razavi, D Razavi-Shearer, O Galárraga, L E Taylor, B D L Marshall
We utilized a disease progression model to predict the number of viraemic infections, cirrhotic cases, and liver-related deaths in the state of Rhode Island (RI) under four treatment scenarios: (1) current HCV treatment paradigm (about 215 patients treated annually, Medicaid reimbursement criteria fibrosis stage ⩾F3); (2) immediate scale-up of treatment (to 430 annually) and less restrictive Medicaid reimbursement criteria (fibrosis stage ⩾F2); (3) immediate treatment scale-up and no fibrosis stage-specific Medicaid reimbursement criteria (⩾F0); (4) an 'elimination' scenario (i...
August 5, 2016: Epidemiology and Infection
https://www.readbyqxmd.com/read/27478986/costs-along-the-htc-and-pmtct-service-cascades-findings-from-kenya-rwanda-south-africa-and-zambia
#14
Sergio Bautista-Arredondo, Sandra G Sosa-Rubí, Marjorie Opuni, David Contreras-Loya, Ada Kwan, Claire Chaumont, Abson Chompolola, Jeanine Condo, Omar Galárraga, Neil Martinson, Felix Masiye, Sabin Nsanzimana, Ivan Ochoa-Moreno, Richard Wamai, Joseph Wang'ombe
OBJECTIVE: We estimate facility-level average annual cost per client along the HIV testing and counselling (HTC) and prevention of mother-to-child transmission (PMTCT) service cascades. DESIGN: Data were collected from 2011-2013 in 230 HTC and 212 PMTCT facilities in Kenya, Rwanda, South Africa, and Zambia. METHODS: Input quantities and unit prices were collected, as were output data. Annual economic costs were estimated from the service providers' perspective using micro-costing...
July 29, 2016: AIDS
https://www.readbyqxmd.com/read/27475643/community-based-interventions-to-improve-and-sustain-antiretroviral-therapy-adherence-retention-in-hiv-care-and-clinical-outcomes-in-low-and-middle-income-countries-for-achieving-the-unaids-90-90-90-targets
#15
REVIEW
Jean B Nachega, Olatunji Adetokunboh, Olalekan A Uthman, Amy W Knowlton, Frederick L Altice, Mauro Schechter, Omar Galárraga, Elvin Geng, Karl Peltzer, Larry W Chang, Gilles Van Cutsem, Shabbar S Jaffar, Nathan Ford, Claude A Mellins, Robert H Remien, Edward J Mills
Little is known about the effect of community versus health facility-based interventions to improve and sustain antiretroviral therapy (ART) adherence, virologic suppression, and retention in care among HIV-infected individuals in low- and middle-income countries (LMICs). We systematically searched four electronic databases for all available randomized controlled trials (RCTs) and comparative cohort studies in LMICs comparing community versus health facility-based interventions. Relative risks (RRs) for pre-defined adherence, treatment engagement (linkage and retention in care), and relevant clinical outcomes were pooled using random effect models...
October 2016: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/27461837/prevalence-of-sleep-disorders-and-their-relationship-with-core-symptoms-of-inattention-and-hyperactivity-in-children-with-attention-deficit-hyperactivity-disorder
#16
Rosario Vélez-Galarraga, Francisco Guillén-Grima, Nerea Crespo-Eguílaz, Rocío Sánchez-Carpintero
OBJECTIVES: To determine the prevalence of sleep disorders in children with attention-deficit/hyperactivity disorder (ADHD) and in a control population. To examine the relationship between sleep disorders and symptoms of inattention, hyperactivity/impulsiveness and executive dysfunction. MATERIALS AND METHODS: We studied 126 children with ADHD and 1036 control children aged between 5 and 18 years old. Caregivers completed the Pediatric Sleep Questionnaire and the ADHD Rating Scale (ADHD-RS)...
November 2016: European Journal of Paediatric Neurology: EJPN
https://www.readbyqxmd.com/read/27440883/complementary-effects-of-interleukin-15-and-alpha-interferon-induce-immunity-in-hepatitis-b-virus-transgenic-mice
#17
Marianna Di Scala, Itziar Otano, Irene Gil-Fariña, Lucia Vanrell, Mirja Hommel, Cristina Olagüe, Africa Vales, Miguel Galarraga, Laura Guembe, Carlos Ortiz de Solorzano, Indrajit Ghosh, Mala K Maini, Jesús Prieto, Gloria González-Aseguinolaza
UNLABELLED: In chronic hepatitis B (CHB), failure to control hepatitis B virus (HBV) is associated with T cell dysfunction. HBV transgenic mice mirror many features of the human disease, including T cell unresponsiveness, and thus represent an appropriate model in which to test novel therapeutic strategies. To date, the tolerant state of CD8(+) T cells in these animals could be altered only by strong immunogens or by immunization with HBV antigen-pulsed dendritic cells; however, the effectors induced were unable to suppress viral gene expression or replication...
October 1, 2016: Journal of Virology
https://www.readbyqxmd.com/read/27417264/the-impact-of-social-health-insurance-on-diabetes-and-hypertension-process-indicators-among-older-adults-in-mexico
#18
Maricruz Rivera-Hernandez, Momotazur Rahman, Vincent Mor, Omar Galarraga
OBJECTIVE: To examine the impact of Seguro Popular (Mexican social health insurance for the poor; SP) on diabetes and hypertension care, intermediate process indicators for older adults (>50 years): pharmacological treatment, blood glucose tests, the use of complementary and alternative medicine (CAM), and adherence to their nutrition and exercise program. (CAM was defined as products or practices that were not part of the medical standard of care.) DATA SOURCES/STUDY SETTING: Repeated cross-sectional surveys from Encuesta Nacional de Salud y Nutrición (Mexican Health and Nutrition Survey, ENSANUT), a nationally representative health and nutrition survey sampling N = 45,294 older adults in 2000, N = 45,241 older adults in 2005-2006, and N = 46,277 older adults in 2011-2012...
August 2016: Health Services Research
https://www.readbyqxmd.com/read/27272890/retention-in-care-among-hiv-infected-adults-in-ethiopia-2005-2011-a-mixed-methods-study
#19
Yordanos M Tiruneh, Omar Galárraga, Becky Genberg, Ira B Wilson
BACKGROUND: Poor retention in HIV care challenges the success of antiretroviral therapy (ART). This study assessed how well patients stay in care and explored factors associated with retention in the context of an initial ART rollout in Sub-Saharan Africa. METHODS: We conducted a mixed-methods study at a teaching hospital in Addis Ababa, Ethiopia. A cohort of 385 patients was followed for a median of 4.6 years from ART initiation to lost-to-follow-up (LTFU-missing appointments for more than three months after last scheduled visit or administrative censoring)...
2016: PloS One
https://www.readbyqxmd.com/read/27167657/genotypes-distribution-of-human-papillomavirus-in-cervical-samples-of-ecuadorian-women
#20
Gustavo David García Muentes, Lindsay Karen García Rodríguez, Ramiro Israel Burgos Galarraga, Franklin Almeida Carpio, Juan Carlos Ruiz Cabezas
INTRODUCTION: Human papillomavirus (HPV) is considered a necessary causative agent for developing oropharyngeal, anal and cervical cancer. Among women in Ecuadorian population, cervical cancer ranks as the second most common gynecological cancer. Not many studies about HPV burden have been published in Ecuador, and genotypes distribution has not been established yet. The little data available suggest the presence of other genotypes different than 16 and 18. OBJECTIVES: In the present study, we attempt to estimate the prevalence of HPV 16, HPV 18 and other 35 genotypes among Ecuadorian women undergoing cervical cancer screening...
March 2016: Revista Brasileira de Epidemiologia, Brazilian Journal of Epidemiology
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