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https://www.readbyqxmd.com/read/29201045/functional-bowel-disorders-are-associated-with-a-central-immune-activation
#1
Per G Farup, Thor Ueland, Knut Rudi, Stian Lydersen, Knut Hestad
Background: Subjects with depression and unexplained neurological symptoms have a high prevalence of gastrointestinal comorbidity probably related to the brain-gut communication. This study explored associations between functional gastrointestinal disorders (FGID) and inflammatory markers in subjects with these disorders. Methods: The FGID, including irritable bowel syndrome (IBS), were classified according to the Rome III criteria, and degree of symptoms was assessed with IBS symptom severity score (IBS-SSS)...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/29195674/the-role-of-smoking-and-alcohol-behaviour-in-management-of-functional-gastrointestinal-disorders
#2
REVIEW
Bodil Ohlsson
Functional gastrointestinal disorders (FGIDs) are common disorders in the population. Lifestyle habits have been suspected to influence the presence and degree of symptoms, and many studies have examined the role of food components and physical activity on the disease development. The role of smoking and alcohol intake on FGID has been less thoroughly examined. This systematic literature review, of a large amount of studies from different countries around the world with different design and application of FGID criteria, shows that smoking seems to be associated with a significant 50% increased risk of FD for current compared with never smokers...
October 2017: Best Practice & Research. Clinical Gastroenterology
https://www.readbyqxmd.com/read/29138194/the-costs-of-functional-gastrointestinal-disorders-and-related-signs-and-symptoms-in-infants-a-systematic-literature-review-and-cost-calculation-for-england
#3
James Mahon, Carlos Lifschitz, Thomas Ludwig, Nikhil Thapar, Julie Glanville, Mohamad Miqdady, Miguel Saps, Seng Hock Quak, Irene Lenoir Wijnkoop, Mary Edwards, Hannah Wood, Hania Szajewska
OBJECTIVES: To estimate the cost of functional gastrointestinal disorders (FGIDs) and related signs and symptoms in infants to the third party payer and to parents. STUDY DESIGN: To estimate the cost of illness (COI) of infant FGIDs, a two-stage process was applied: a systematic literature review and a COI calculation. As no pertinent papers were found in the systematic literature review, a 'de novo' analysis was performed. For the latter, the potential costs for the third party payer (the National Health Service (NHS) in England) and for parents/carers for the treatment of FGIDs in infants were calculated, by using publicly available data...
November 14, 2017: BMJ Open
https://www.readbyqxmd.com/read/29134969/the-prevalence-and-impact-of-overlapping-rome-iv-diagnosed-functional-gastrointestinal-disorders-on-somatization-quality-of-life-and-healthcare-utilization-a-cross-sectional-general-population-study-in-three-countries
#4
Imran Aziz, Olafur S Palsson, Hans Törnblom, Ami D Sperber, William E Whitehead, Magnus Simrén
OBJECTIVES: The population prevalence of Rome IV-diagnosed functional gastrointestinal disorders (FGIDs) and their cumulative effect on health impairment is unknown. METHODS: An internet-based cross-sectional health survey was completed by 5,931 of 6,300 general population adults from three English-speaking countries (2100 each from USA, Canada, and UK). Quota-based sampling was used to generate demographically balanced and population representative samples with regards to age, sex, and education level...
November 14, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29134293/medicinal-foods-for-functional-gi-disorders
#5
REVIEW
Brent W Acker, Brooks D Cash
PURPOSE OF REVIEW: Over the past 10 years, there has been a dramatic increase in basic and clinical research involving functional gastrointestinal disorders (FGIDs). New diagnostic and biomarker procedures are helping to identify physiologic disruptions associated with FGIDs on cellular and molecular levels. Simultaneously, clinicians are using new approaches to help manage patients with FGIDs. Among these, an important component of care has been the use of medical foods. These include probiotics, prebiotics, synbiotics, peppermint oil, caraway oil, curcumin, bovine immunoglobulin and many others...
November 13, 2017: Current Gastroenterology Reports
https://www.readbyqxmd.com/read/29129667/prevalence-of-functional-gastrointestinal-disorders-in-children-and-adolescents-in-the-mediterranean-region-of-europe
#6
Elena Scarpato, Sanja Kolacek, Danijela Jojkic-Pavkov, Vlatka Konjik, Nataša Živković, Enriqueta Roman, Aco Kostovski, Nikolina Zdraveska, Eyad Altamimi, Alexandra Papadopoulou, Thomai Karagiozoglou-Lampoudi, Raanan Shamir, Michal Rozenfeld Bar Lev, Aziz Koleilat, Sirin Mneimneh, Dario Bruzzese, Rosaura Leis, Annamaria Staiano
BACKGROUND & AIMS: Little is known about the prevalence of functional gastrointestinal disorders (FGIDs) in children from the Mediterranean area of Europe. We aimed to assess the prevalence of FGIDs in children and adolescents in this region. METHODS: We collected data on 13,750 children (4-18 years old) enrolled in the Mediterranean-European Area Project, a school-based health study performed in Croatia, Greece, Israel, Italy, Jordan, Lebanon, Macedonia, Serbia, and Spain...
November 9, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/29112086/randomized-controlled-clinical-trial-on-value-of-domperidone-in-functional-abdominal-pain-in-children
#7
Amaranath Karunanayake, Niranga M Devanarayana, Asita de Silva, Sampath Gunawardena, Shaman Rajindrajith
OBJECTIVES: The aim of the study was to evaluate the therapeutic effect of domperidone on children with abdominal pain predominant functional gastrointestinal disorders (AP-FGIDs). METHODS: One hundred children (aged 5-12 years) fulfilling Rome III criteria for AP-FGIDs were randomized into 8 weeks of domperidone or placebo treatment. Primary outcomes defined were cure and patient-reported general improvement. Secondary outcomes were reduction in the severity of abdominal pain and increase in gastric motility...
November 3, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/29094806/performance-of-an-algorithm-based-approach-to-the-diagnosis-and-management-of-functional-gastrointestinal-disorders-a-pilot-trial
#8
E C Linedale, A Mikocka-Walus, A D Vincent, P R Gibson, J M Andrews
BACKGROUND: Recent advances in the development of diagnostic criteria and effective management options for functional gastrointestinal disorders (FGIDs) have not yet been integrated into clinical practice. There is a clear need for the development and validation of a simple clinical pathway for the diagnosis and management of FGIDs which can be used in primary care. METHODS: In this controlled pilot study, we designed and evaluated a non-specialist-dependent, algorithm-based approach for the diagnosis and management of FGIDs (ADAM-FGID)...
November 2, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/29072609/rome-criteria-and-a-diagnostic-approach-to-irritable-bowel-syndrome
#9
REVIEW
Brian E Lacy, Nihal K Patel
Functional gastrointestinal disorders (FGIDs) account for at least 40% of all referrals to gastroenterologists. Of the 33 recognized adult FGIDs, irritable bowel syndrome (IBS) is the most prevalent, with a worldwide prevalence estimated at 12%. IBS is an important health care concern as it greatly affects patients' quality of life and imposes a significant economic burden to the health care system. Cardinal symptoms of IBS include abdominal pain and altered bowel habits. The absence of abdominal pain makes the diagnosis of IBS untenable...
October 26, 2017: Journal of Clinical Medicine
https://www.readbyqxmd.com/read/28992677/nationwide-multicenter-study-for-overlaps-of-common-functional-gastrointestinal-disorders-in-korean-patients-with-constipation
#10
Kyung Sik Park, Sam Ryong Jee, Bong Eun Lee, Kyoung Sup Hong, Jeong Eun Shin, Soo-Young Na, Joong Goo Kwon, Suck Chei Choi, Yong Sung Kim, Hyun Seok Lee, Tae Hee Lee, Kyeong Ok Kim, Jongkyoung Choi, Hee Seok Moon, Yeon Soo Kim, Moo In Park, Soo Jung Park, Seon-Young Park, Sung Noh Hong
Background/Aims: In spite of increased concerns about the overlaps among the various functional gastrointestinal disorders (FGIDs), studies for the overlap between constipation and other common FGIDs are rare. Therefore, we investigated the patterns of overlaps between constipation and other common FGIDs. Methods: This study was designed as a prospective nationwide multi-center questionnaire study using Rome III questionnaires for functional dyspepsia (FD), irritable bowel syndrome (IBS), and functional constipation (FC), as well as various questionnaires about patients' information, degree of symptoms, and quality of life...
October 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28954618/diagnosis-and-management-of-irritable-bowel-syndrome-a-guide-for-the-generalist
#11
REVIEW
Ecushla C Linedale, Jane M Andrews
Irritable bowel syndrome (IBS) and other functional gastrointestinal disorders (FGIDs) are so prevalent they cannot reasonably have their diagnoses and management based within specialty care. However, delayed diagnosis, lengthy wait times for specialist review, overinvestigation and lack of clear diagnostic communication are common. The intrusive symptoms of IBS and other FGIDs impair patient functioning and reduce quality of life, and come with significant costs to individual patients and the health care system, which could be reduced with timely diagnosis and effective management...
September 2, 2017: Medical Journal of Australia
https://www.readbyqxmd.com/read/28845170/psychological-factors-influence-the-irritable-bowel-syndrome-and-their-effect-on-quality-of-life-among-firefighters-in-south-korea
#12
Seung-Ho Jang, Han-Seung Ryu, Suck-Chei Choi, Sang-Yeol Lee
OBJECTIVE: The purpose of this study was to investigate the characteristics of psychological factors that are related to irritable bowel syndrome (IBS) and their effects on the quality of life (QOL) of firefighters in South Korea. METHODS: This study examined data collected from 1217 firefighters in South Korea. After identifying firefighters with IBS according to the Rome III diagnostic criteria for functional gastrointestinal disorders (FGIDs), we collected demographic data and psychological variables through self-administered questionnaires...
July 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/28837511/functional-gastrointestinal-disorders-and-joint-hypermobility-a-school-based-study
#13
Miguel Saps, Puck J J Blom, Carlos Alberto Velasco-Benitez, Marc Alexander Benninga
OBJECTIVES: To assess the prevalence of JH among school-children with and without FGIDs. METHODS: School-children completed validated Rome III questionnaires to diagnose FGID. Each child diagnosed with a FGID was matched for age and gender with a healthy control. The prevalence of JH in both groups was compared. RESULTS: 654 school-children participated in the study. One hundred and forty-eight (22.6%) children were diagnosed with a FGID. Data from 136 FGIDs and 136 healthy controls was analyzed...
August 23, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28826271/the-role-of-fermentable-carbohydrates-and-beverages-in-the-symptomatology-of-functional-gastrointestinal-disease
#14
Magnus Moding, Bodil Ohlsson
OBJECTIVES: The pathophysiology behind functional gastrointestinal disease (FGID) has not been defined, but an intestinal accumulation of fermentable short-chain carbohydrates (FODMAPs) is thought to be involved. A restricted coffee intake is recommended. The aim was to investigate if symptoms of FGID were associated with intake of certain foods (including FODMAPs), as well as beverages (including coffee and tea). METHOD AND MATERIALS: Data were used from participants, age range 45-75 years, who had answered the EpiHealth questionnaire about their background factors, health status and intake of food and beverages...
August 21, 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/28814481/plausibility-criteria-for-putative-pathophysiological-mechanisms-in-functional-gastrointestinal-disorders-a-consensus-of-experts
#15
Jan Tack, Maura Corsetti, Michael Camilleri, Eamonn Mm Quigley, Magnus Simren, Hidekazu Suzuki, Nicholas J Talley, Hans Tornblom, Lukas Van Oudenhove
BACKGROUND AND AIMS: The functional gastrointestinal disorders (FGIDs) are extremely common conditions associated with a considerable personal, social and health economic burden. Managing FGIDs in clinical practice is challenging because of the uncertainty of symptom-based diagnosis, the high frequency of overlap between these conditions and the limited efficacy of available therapies. It has often been argued that successful drug development and management of FGIDs requires knowledge of the underlying pathophysiology...
August 16, 2017: Gut
https://www.readbyqxmd.com/read/28798012/internet-delivered-cognitive-behavioral-therapy-for-children-with-pain-related-functional-gastrointestinal-disorders-feasibility-study
#16
Maria Lalouni, Brjánn Ljótsson, Marianne Bonnert, Erik Hedman-Lagerlöf, Jens Högström, Eva Serlachius, Ola Olén
BACKGROUND: Pain-related functional gastrointestinal disorders (P-FGIDs; eg, irritable bowel syndrome) are highly prevalent in children and associated with low quality of life, anxiety, and school absence. Treatment options are scarce, and there is a need for effective and accessible treatments. Internet-delivered cognitive behavior therapy (Internet-CBT) based on exposure exercises is effective for adult and adolescent irritable bowel syndrome, but it has not been evaluated for younger children...
August 10, 2017: JMIR Mental Health
https://www.readbyqxmd.com/read/28745840/cyclic-vomiting-syndrome-is-a-prevalent-and-under-recognized-condition-in-the-gastroenterology-outpatient-clinic
#17
R C Sagar, R Sood, D J Gracie, M J Gold, N To, G R Law, A C Ford
BACKGROUND: Cyclic vomiting syndrome (CVS) is a functional gastrointestinal disorder (FGID) characterized by intermittent episodes of nausea and vomiting. Our aim was to report its prevalence and associated features. METHODS: Data concerning demographics, symptoms, and psychiatric comorbidity were collected. Symptoms compatible with CVS were classified as per Rome III criteria. We recorded whether a diagnosis of CVS was considered in patients after negative investigation...
July 26, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28744774/early-onset-of-efficacy-in-patients-with-functional-and-motility-related-gastrointestinal-disorders-a%C3%A2-noninterventional-study-with-iberogast%C3%A2
#18
Richard Raedsch, Bettina Vinson, Bertram Ottillinger, Gerald Holtmann
STW 5 (Iberogast®; Steigerwald Arzneimittelwerk GmbH, Darmstadt, Germany) contains nine plant extracts and possesses well-documented overall efficacy in functional gastrointestinal disorders (FGID). Little is known about the onset of symptom relief. Twenty-nine centers in Germany recruited 272 patients with established FGID. These patients were treated with STW 5 for approximately 3 weeks in this noninterventional study. Patients assessed the severity of their gastrointestinal complaints before and at defined times after the intake of STW 5 (10 cm visual analogue scale; VAS)...
July 25, 2017: Wiener Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28737582/a-nutritional-approach-for-managing-irritable-bowel-syndrome
#19
Natalie Bhesania, Gail A M Cresci
PURPOSE OF REVIEW: Irritable bowel syndrome (IBS) is the most common functional gastrointestinal disorder (FGID) encountered by the pediatrician and consultant. The primary focus of this review is to provide an update on beneficial nutritional interventions for managing this patient population with discussion on gut microbiome effects. RECENT FINDINGS: A common complaint among the pediatric population is IBS-related recurrent abdominal pain. The prevalence of IBS is estimated to range between 6 and 14% and is defined by the Rome III criteria for FGIDs...
October 2017: Current Opinion in Pediatrics
https://www.readbyqxmd.com/read/28707297/functional-gastrointestinal-disorders-in-children-from-low-socio-economic-status-and-helicobacter-pylori-infection
#20
F Jaime, A Villagrán, C Hernández, M Ortiz, C Serrano, P R Harris
BACKGROUND: Most studies on functional gastrointestinal disorders (FGIDs) in children are based on data from the northern hemisphere. Scientific reports are arising in South American population, but little is still known about children from low socio-economic status (SES), where Helicobacter pylori infection is endemic. Our objective was to evaluate the prevalence of FGIDs in school children from low SES and its relationship with H. pylori infection. METHODS: Children from 3 public schools of low SES from Santiago de Chile were included...
July 14, 2017: Child: Care, Health and Development
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