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https://www.readbyqxmd.com/read/27849120/review-gut-microbiota-and-functional-diseases-of-the-gastrointestinal-tract
#1
Nicola Imperatore, Raffaella Tortora, Filomena Morisco, Nicola Caporaso
INTRODUCTION: Functional gastrointestinal disorders (FGIDs) are a common group of chronic gastrointestinal (GI) diseases defined by symptom-based diagnostic criteria, which consider chronic or recurrent symptoms of the GI tract in the absence of other organic or biochemical reasons. Recent evidences have been highlighted the role of gut microbiota in the pathophysiology of the FGIDs. EVIDENCE ACQUISITION: We focused our attention on critically analysis of the existing literature on the role of gut microbiota in FGIDs, by evaluating the differences of composition, functions and role of intestinal flora in FGIDs of the upper and lower gastrointestinal tract...
November 16, 2016: Minerva Gastroenterologica e Dietologica
https://www.readbyqxmd.com/read/27756121/associations-between-excessive-daytime-sleepiness-and-functional-gastrointestinal-disorders-a-population-based-study-in-china
#2
Sicheng Wu, Shuqi Chen, Yanfang Zhao, Xiuqiang Ma, Rui Wang, Jia He
Background/Aims: Several studies have demonstrated that sleep problems are associated with functional gastrointestinal disorders (FGIDs), such as irritable bowel syndrome (IBS), and functional dyspepsia etc, but the relationship between excessive daytime sleepiness (EDS) and FGIDs has not been systematically studied in general population. This study aimed to explore the relationship between EDS and specific types of FGIDs and the effect of the number of FGIDs on EDS. Methods: A sample of 3600 individuals (aged 18-80 years) was selected from 5 regions in China using a randomized stratified multi-stage sampling method...
October 17, 2016: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/27743332/gastrointestinal-symptoms-predictors-of-health-related-quality-of-life-in-pediatric-patients-with-functional-gastrointestinal-disorders
#3
James W Varni, Robert J Shulman, Mariella M Self, Samuel Nurko, Miguel Saps, Shehzad A Saeed, Ashish S Patel, Chelsea Vaughan Dark, Cristiane B Bendo, John F Pohl
OBJECTIVES: To investigate the patient-reported multidimensional gastrointestinal symptoms predictors of generic health-related quality of life (HRQOL) in pediatric patients with functional gastrointestinal disorders (FGIDs). METHODS: The Pediatric Quality of Life Inventory™ (PedsQL™) Gastrointestinal Symptoms Scales and PedsQL™ 4.0 Generic Core Scales were completed in a 9-site study by 259 pediatric patients with functional constipation, functional abdominal pain (FAP), or irritable bowel syndrome (IBS)...
October 14, 2016: Quality of Life Research
https://www.readbyqxmd.com/read/27738596/middle-east-consensus-statement-on-the-diagnosis-and-management-of-functional-gastrointestinal-disorders-in-12-months-old-infants
#4
Yvan Vandenplas, Muath Abdurrahman Alturaiki, Wafaa Al-Qabandi, Fawaz AlRefaee, Ziad Bassil, Bassam Eid, Ahmed El Beleidy, Ali Ibrahim Almehaidib, Pierre Mouawad, Maroun Sokhn
This paper covers algorithms for the management of regurgitation, constipation and infantile colic in infants. Anti-regurgitation formula may be considered in infants with troublesome regurgitation, while diagnostic investigations or drug therapy are not indicated in the absence of warning signs. Although probiotics have shown some positive evidence for the management of functional gastrointestinal disorders (FGIDs), the evidence is not strong enough to make a recommendation. A partially hydrolyzed infant formula with prebiotics and β-palmitate may be considered as a dietary intervention for functional constipation in formula fed infants...
September 2016: Pediatric Gastroenterology, Hepatology & Nutrition
https://www.readbyqxmd.com/read/27736943/exposure-based-cognitive-behavior-therapy-for-children-with-abdominal-pain-a-pilot-trial
#5
Maria Lalouni, Ola Olén, Marianne Bonnert, Erik Hedman, Eva Serlachius, Brjánn Ljótsson
BACKGROUND: Children with pain-related functional gastrointestinal disorders (P-FGIDs) have an increased risk for school absenteeism, depression, anxiety and low quality of life. Exposure-based cognitive behavior therapy (CBT) has shown large treatment effects in adults with irritable bowel syndrome, but has not been tested for children 8-12 years with P-FGIDs. AIM: The aim of this trial was to test the feasibility, acceptability and potential efficacy of a newly developed exposure-based CBT for children with P-FGIDs...
2016: PloS One
https://www.readbyqxmd.com/read/27726867/a-population-based-study-on-the-epidemiology-of-functional-gastrointestinal-disorders-in-young-children
#6
Ashish Chogle, Carlo A Velasco-Benitez, Ilan J Koppen, Jairo E Moreno, Carmen R Ramírez Hernández, Miguel Saps
OBJECTIVE: To perform a population-based study with Rome III criteria to describe the prevalence of functional gastrointestinal disorders (FGIDs) in children in Colombia. STUDY DESIGN: We conducted a multicity cross-sectional study to investigate the epidemiology of FGIDs in children 0-48 months of age using the Rome III criteria in Colombia. Children with organic medical diseases were excluded. Parents provided demographic information and completed the Spanish version of the Questionnaire on Pediatric Gastrointestinal Symptoms for Infants & Toddlers...
October 7, 2016: Journal of Pediatrics
https://www.readbyqxmd.com/read/27698540/influence-of-regular-exercise-on-gastric-emptying-in-healthy-men-a-pilot-study
#7
Juntaro Matsuzaki, Hidekazu Suzuki, Tatsuhiro Masaoka, Kentaro Tanaka, Hideki Mori, Takanori Kanai
Functional gastrointestinal disorders (FGIDs), including functional dyspepsia (FD), are common chronic disorders even in the younger population. Physical activity is advocated for patients with FGIDs, although the evidence is insufficient. We investigated the association between the intensity of regular exercise and gastric emptying to determine the effect of physical activity on dyspeptic symptoms. Thirty healthy individuals were selected and divided into three groups (low, moderate, and high) using the index of total exercise intensity in a week...
September 2016: Journal of Clinical Biochemistry and Nutrition
https://www.readbyqxmd.com/read/27681080/clinical-experience-with-the-use-of-anti-cdtb-and-anti-vinculin-antibodies-in-patients-with-diarrhea-in-mexico
#8
M Schmulson, R Balbuena, C Corona de Law
INTRODUCTION: Circulating anti-CdtB/anti-vinculin antibodies have been validated as biomarkers to distinguish IBS-D from IBD, but there is no experience with them in Latin America. MATERIALS AND METHODS: The analysis was carried out on patients seen at a FGIDs/motility clinic over the last 7 months for diarrhea with abdominal pain and/or bloating who were tested for these antibodies. The patients were diagnosed according to the Rome III criteria or with organic disorders, and those presenting with IBS were further classified as post-infectious (PI) or non-PI-IBS...
October 2016: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/27679978/functional-gastrointestinal-disorders-in-greek-children-based-on-rome-iii-criteria-identifying-the-child-at-risk
#9
I Bouzios, G Chouliaras, G P Chrousos, E Roma, V Gemou-Engesaeth
BACKGROUND: Functional gastrointestinal disorders (FGIDs) are a common, diverse group of disorders of unknown etiology, resulting in significant socieconomic burden. In this study, we aimed to assess the prevalence of FGIDs in children aged 6-18 years and examine their association with various demographic and socioeconomic parameters. METHODS: This was a school-based, cross-sectional study approved by the relevant government authorities. Informed consent was obtained by the legal representatives of all children who participated...
September 28, 2016: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/27605889/epidemiology-of-functional-gastrointestinal-disorders-in-infants-and-toddlers-a-systematic-review
#10
Ana Paula Ferreira-Maia, Alicia Matijasevich, Yuan-Pang Wang
AIM: To assess the functional gastrointestinal disorders (FGID) prevalence in infants and toddlers. METHODS: PubMed, EMBASE, and Scopus were searched for original articles from inception to February 2016. The literature search was made in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). For inclusion, each study had to report epidemiological data of FGID on children up to 4 years old and contain standardized outcome Rome II or III criteria...
July 28, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27594888/changes-in-the-interstitial-cells-of-cajal-and-immunity-in-chronic-psychological-stress-rats-and-therapeutic-effects-of-acupuncture-at-the-zusanli-point-st36
#11
Mucang Liu, Shenglin Zhang, Yue Gai, Mingzheng Xie, Qinghui Qi
Now, chronic psychological stress (CPS) related diseases are increasing. Many CPS patients have gastrointestinal complaints, immune suppression, and immune imbalance. Increasing evidence is indicating that acupuncture (AP) at the Zusanli point (ST36) can alleviate functional gastrointestinal disorders (FGID), immune suppression, and immune imbalance. However, few studies have investigated the potential mechanisms. In this study, CPS rat models were established, and electroacupuncture (EA) at ST36 was done for CPS rats...
2016: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/27569716/distinct-resting-state-brain-activity-in-patients-with-functional-constipation
#12
Qiang Zhu, Weiwei Cai, Jianyong Zheng, Guanya Li, Qianqian Meng, Qiaoyun Liu, Jizheng Zhao, Karen M von Deneen, Yuanyuan Wang, Guangbin Cui, Shijun Duan, Yu Han, Huaning Wang, Jie Tian, Yi Zhang, Yongzhan Nie
Functional constipation (FC) is a common functional gastrointestinal disorder (FGID) with a higher prevalence in clinical practice. The primary brain regions involved in emotional arousal regulation, somatic, sensory and motor control processing have been identified with neuroimaging in FGID. It remains unclear how these factors interact to influence the baseline brain activity of patients with FC. In the current study, we combined resting-state fMRI (RS-fMRI) with Granger causality analysis (GCA) to investigate the causal interactions of the brain areas in 14 patients with FC and in 26 healthy controls (HC)...
October 6, 2016: Neuroscience Letters
https://www.readbyqxmd.com/read/27558903/costs-associated-with-functional-gastrointestinal-disorders-and-related-signs-and-symptoms-in-infants-a-systematic-review-protocol
#13
Julie Glanville, Thomas Ludwig, Carlos Lifschitz, James Mahon, Mohamad Miqdady, Miguel Saps, Seng Hock Quak, Irene Lenoir-Wijnkoop, Mary Edwards, Hannah Wood, Hania Szajewska
INTRODUCTION: Functional gastrointestinal disorders (FGIDs) and FGID-related signs and symptoms have a fundamental impact on the psychosocial, physical and mental well-being of infants and their parents alike. Recent reviews and studies have indicated that FGIDs and related signs and symptoms may also have a substantial impact on the budgets of third-party payers and/or parents. The objective of this systematic review is to investigate these costs. METHODS AND ANALYSIS: The population of interest is healthy term infants (under 12 months of age) with colic, regurgitation and/or functional constipation...
August 24, 2016: BMJ Open
https://www.readbyqxmd.com/read/27554498/prevalence-of-functional-gastrointestinal-disorders-among-adolescents-in-delhi-based-on-rome-iii-criteria-a-school-based-survey
#14
Vidyut Bhatia, Shivani Deswal, Swati Seth, Akshay Kapoor, Anupam Sibal, Sarath Gopalan
BACKGROUND: Functional gastrointestinal diseases (FGIDs) are emerging as an important cause of morbidity in adolescents globally. The prevalence of FGIDs among Indian children or adolescents is not clear. METHODS: A cross-sectional school-based survey conducted in 1115 children aged 10-17 years attending four semi urban government schools of National capital territory (NCT) of Delhi. Rome III questionnaire was translated into Hindi and was filled by the students under supervision...
July 2016: Indian Journal of Gastroenterology: Official Journal of the Indian Society of Gastroenterology
https://www.readbyqxmd.com/read/27546626/prevalence-of-functional-gastrointestinal-disorders-in-mexican-schoolchildren
#15
G Dhroove, M Saps, C Garcia-Bueno, A Levya Jiménez, L L Rodriguez-Reynosa, C A Velasco-Benítez
INTRODUCTION AND AIMS: Functional gastrointestinal disorders are among the most common chronic disorders in children worldwide. Studies in schoolchildren from various Latin American countries have shown a high prevalence of functional gastrointestinal disorders, but their prevalence in Mexican schoolchildren is unknown. Our aim was to assess the prevalence of functional gastrointestinal disorders in Mexican schoolchildren in accordance with the Rome III criteria. MATERIAL AND METHODS: Children and adolescents from public and private schools in Monterrey and Cuernavaca privately completed the Spanish version of the Questionnaire on Pediatric Gastrointestinal Symptoms-Rome III Version (QPGS-III) in class, using the same methods and questionnaires of previous studies conducted by our group in other Latin American countries...
August 19, 2016: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/27514480/ion-channelopathies-in-functional-gi-disorders
#16
Arthur Beyder, Gianrico Farrugia
In the gastrointestinal (GI) tract, abnormalities in secretion, absorption, motility, and sensation have been implicated in functional gastrointestinal disorders (FGIDs). Ion channels play important roles in all these GI functions. Disruptions of ion channels' ability to conduct ions can lead to diseases called ion channelopathies. Channelopathies can result from changes in ion channel biophysical function or expression due to mutations, posttranslational modification, and accessory protein malfunction. Channelopathies are strongly established in the fields of cardiology and neurology, but ion channelopathies are only beginning to be recognized in gastroenterology...
October 1, 2016: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/27444264/evidence-that-independent-gut-to-brain-and-brain-to-gut-pathways-operate-in-the-irritable-bowel-syndrome-and-functional-dyspepsia-a-1-year-population-based-prospective-study
#17
N A Koloski, M Jones, N J Talley
BACKGROUND: Traditionally, functional gastrointestinal disorders (FGIDs) are conceptualised as originating in the brain via stress pathways (brain-to-gut). It is uncertain how many with irritable bowel syndrome (IBS) and functional dyspepsia (FD) have a gut origin of symptoms (gut-to-brain pathway). AIMS: To determine if there is a distinct brain-to-gut FGID (where psychological symptoms begin first) and separately a distinct gut-to-brain FGID (where gut symptoms start first)...
September 2016: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/27437930/risk-categorization-predicts-disability-in-pain-associated-functional-gastrointestinal-disorders-fgids-after-6-months
#18
Natoshia Raishevich Cunningham, Anjana Jagpal, James Peugh, Michael K Farrell, Mitchell B Cohen, Adam G Mezoff, Anne Lynch-Jordan, Susmita Kashikar-Zuck
INTRODUCTION: For a large portion of youth, pain-associated functional gastrointestinal disorders (FGIDs) are associated with significant impairment over time. Clinically feasible methods to categorize youth with FGIDs at greatest risk for persistent pain-related impairment have not yet been identified. METHODS: Measures of functional disability, pain intensity and anxiety were collected on 99 patients with FGIDs (ages 8-18) during a visit to a pediatric gastroenterology office to assess for the presence of risk...
July 20, 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27437927/functional-dyspepsia-an-enigma-in-a-conundrum
#19
Claudio Romano, Simona Valenti, Sabrina Cardile, Marc A Benninga
As defined by Rome III, there are 4 abdominal pain-related functional gastrointestinal disorders in children: irritable bowel syndrome, functional dyspepsia (FD), abdominal migraine, and functional abdominal pain. Dyspepsia is a constellation of symptoms referable to the gastroduodenal region of the upper gastrointestinal tract. FD refers to dyspeptic symptoms that cannot currently be explained by an organic cause, and affects 25% to 40% of the adult population over a lifetime. In children, this condition results in increased specialist consultations, with reported prevalence between 3% and 27%...
December 2016: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/27423188/pharmacological-interventions-on-early-functional-gastrointestinal-disorders
#20
REVIEW
Silvia Salvatore, Salvatore Barberi, Osvaldo Borrelli, Annamaria Castellazzi, Dora Di Mauro, Giuseppe Di Mauro, Mattia Doria, Ruggiero Francavilla, Massimo Landi, Alberto Martelli, Vito Leonardo Miniello, Giovanni Simeone, Elvira Verduci, Carmen Verga, Maria Assunta Zanetti, Annamaria Staiano
BACKGROUND: Functional gastrointestinal disorders (FGIDs) are chronic or recurrent gastrointestinal symptoms without structural or biochemical abnormalities. FGIDs are multifactorial conditions with different pathophysiologic mechanisms including altered motility, visceral hyperalgesia, brain-gut disturbance, genetic, environmental and psychological factors. Although in most cases gastrointestinal symptoms are transient and with spontaneous resolution in infancy multiple dietary changes and pharmacological therapy are often started despite a lack of evidence-based data...
July 16, 2016: Italian Journal of Pediatrics
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