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Physician peer review

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https://www.readbyqxmd.com/read/28933008/importance-of-publishing-adverse-drug-reaction-case-reports-promoting-public-health-and-advancing-pharmacology-and-therapeutics
#1
Rashmi R Shah
This article, which encourages physicians to publish case reports of adverse drug reactions (ADRs), is a review of how well-documented published case reports have contributed to promoting public safety and health and thus served to advance basic pharmacology. The origin of a number of regulatory guidelines can ultimately be traced to safety concerns triggered by such reports. It illustrates how case reports of ADRs, when coupled with simultaneous monitoring of drug pharmacokinetics, have also led to further investigations resulting in major advances in pharmacology, especially pharmacogenetics, mechanisms of drug-drug interactions and modulation of drug metabolism during inflammatory co-morbidities...
September 20, 2017: Drug Safety—Case Reports
https://www.readbyqxmd.com/read/28929853/physician-leadership-development-evidence-informed-design-tempered-with-real-life-experience
#2
Shawn Jolemore, Steven D Soroka
This article describes key considerations for creation of evidence-informed in-house physician leadership development. Ten elements extracted from a scan of the peer-reviewed and grey literature are presented, and key learnings at the Queen Elizabeth II Health Sciences Centre, a quaternary academic health sciences centre in Halifax, Nova Scotia, are highlighted. Each element is briefly described with practical considerations and challenges to implementation outlined in the context of the former Capital District Health Authority, where the authors collaborated to create in-house physician leadership development prior to the consolidation of health districts in that province...
May 2017: Healthcare Management Forum
https://www.readbyqxmd.com/read/28925860/pharmacologic-and-perioperative-considerations-for-antihypertensive-medications
#3
Sher-Lu Pai, Ryan M Chadha, Joan M Irizarry Alvarado, Johnathan Ross Renew, Stephen Aniskevich
BACKGROUND: As the prevalence of hypertension continues to increase, physicians routinely encounter patients preoperatively receiving one or more cardiovascular medications to manage hypertension. Thus, the physician's knowledge of perioperative antihypertensive medication management is crucial to ensure patient safety. OBJECTIVE: We discuss the decisions to continue or stop antihypertensive medications to reduce the risk of perioperative complications. METHOD: We conducted a review of the original research studies, review articles, and editorials present on PubMed within the past 60 years...
September 18, 2017: Current Clinical Pharmacology
https://www.readbyqxmd.com/read/28924401/the-trump-effect-with-no-peer-review-how-do-we-know-what-to-really-believe-on-social-media
#4
REVIEW
Justin T Brady, Molly E Kelly, Sharon L Stein
Social media is a source of news and information for an increasing portion of the general public and physicians. The recent political election was a vivid example of how social media can be used for the rapid spread of "fake news" and that posts on social media are not subject to fact-checking or editorial review. The medical field is susceptible to propagation of misinformation, with poor differentiation between authenticated and erroneous information. Due to the presence of social "bubbles," surgeons may not be aware of the misinformation that patients are reading, and thus, it may be difficult to counteract the false information that is seen by the general public...
September 2017: Clinics in Colon and Rectal Surgery
https://www.readbyqxmd.com/read/28910335/medical-leaders-or-masters-a-systematic-review-of-medical-leadership-in-hospital-settings
#5
Mathilde A Berghout, Isabelle N Fabbricotti, Martina Buljac-Samardžić, Carina G J M Hilders
Medical leadership is increasingly considered as crucial for improving the quality of care and the sustainability of healthcare. However, conceptual clarity is lacking in the literature and in practice. Therefore, a systematic review of the scientific literature was conducted to reveal the different conceptualizations of medical leadership in terms of definitions, roles and activities, and personal-and context-specific features. Eight databases were systematically searched for eligible studies, including empirical studies published in peer-reviewed journals that included physicians carrying out a manager or leadership role in a hospital setting...
2017: PloS One
https://www.readbyqxmd.com/read/28903578/mental-health-services-use-trends-in-canadian-veterans-a-population-based-retrospective-cohort-study-in-ontario
#6
Alyson L Mahar, Alice B Aiken, Heidi Cramm, Marlo Whitehead, Patti Groome, Paul Kurdyak
OBJECTIVE: A substantial evidence base in the peer-reviewed literature exists investigating mental illness in the military, but relatively less is documented about mental illness in veterans. This study uses provincial, administrative data to study the use of mental health services by Canadian veterans in Ontario. METHOD: This was a retrospective cohort study of Canadian Armed Forces and Royal Canadian Mounted Police veterans who were released between 1990 and 2013 and resided in Ontario...
January 1, 2017: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/28900045/gbcas-and-risk-for-nephrogenic-systemic-fibrosis-a-literature-review
#7
Asher Street Beam, Kristi G Moore, Savannah N Gillis, Kala F Ford, Tyler Gray, Anne Howard Steinwinder, Alexa Graham
PURPOSE: To examine the risks of using of gadolinium-based contrast agents (GBCAs) in magnetic resonance (MR) imaging and explore strategies to reduce the likeliness of adverse effects in patients who might be at risk for developing nephrogenic system fibrosis (NSF). METHODS: A search of 3 scholarly databases was performed to identify articles that discuss adverse reactions to GBCAs, specifically relating to kidney function, in MR examinations. A total of 20 peer-reviewed articles were analyzed...
July 2017: Radiologic Technology
https://www.readbyqxmd.com/read/28895227/comparing-generic-drug-markets-in-europe-and-the-united-states-prices-volumes-and-spending
#8
COMPARATIVE STUDY
Olivier J Wouters, Panos G Kanavos, Martin McKEE
Policy Points: Our study indicates that there are opportunities for cost savings in generic drug markets in Europe and the United States. Regulators should make it easier for generic drugs to reach the market. Regulators and payers should apply measures to stimulate price competition among generic drugmakers and to increase generic drug use. To meaningfully evaluate policy options, it is important to analyze historical context and understand why similar initiatives failed previously. CONTEXT: Rising drug prices are putting pressure on health care budgets...
September 2017: Milbank Quarterly
https://www.readbyqxmd.com/read/28874943/loaded-questions-internet-commenters-opinions-on-physician-patient-firearm-safety-conversations
#9
Christopher E Knoepke, Amanda Allen, Megan L Ranney, Garen J Wintemute, Daniel D Matlock, Marian E Betz
INTRODUCTION: Medical and public health societies advocate that healthcare providers (HCPs) counsel at-risk patients to reduce firearm injury risk. Anonymous online media comments often contain extreme viewpoints and may therefore help in understanding challenges of firearm safety counseling. To help inform injury prevention efforts, we sought to examine commenters' stated opinions regarding firearm safety counseling HCPs. METHODS: Qualitative descriptive analysis of online comments posted following news items (in May-June, 2016) about a peer-reviewed publication addressing when and how HCPs should counsel patients regarding firearms...
August 2017: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28871024/telemedicine-guided-education-on-secondary-stroke-and-fall-prevention-following-inpatient-rehabilitation-for-texas-patients-with-stroke-and-their-caregivers-a-feasibility-pilot-study
#10
Mansi M Jhaveri, Ruby Benjamin-Garner, Nahid Rianon, Mark Sherer, Gerard Francisco, Farhaan Vahidy, Kayta Kobayashi, Mary Gaber, Paige Shoemake, Kim Vu, Alyssa Trevino, James Grotta, Sean Savitz
INTRODUCTION: The aftermath of stroke leaves many consequences including cognitive deficits and falls due to imbalance. Stroke survivors and families struggle to navigate the complex healthcare system with little assistance posthospital discharge, often leading to early hospital readmission and worse stroke outcomes. Telemedicine Guided Education on Secondary Stroke and Fall Prevention Following Inpatient Rehabilitation feasibility study examines whether stroke survivors and their caregivers find value in telerehabilitation (TR) home visits that provide individualised care and education by a multidisciplinary team after discharge from inpatient rehabilitation...
September 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/28861459/development-of-a-comprehensive-and-sustainable-gynecologic-oncology-training-program-in-western-kenya-a-low-resource-setting
#11
Barry Rosen, Peter Itsura, Philip Tonui, Alan Covens, Luc van Lonkhuijzen, Elkanah Omenge Orang'o
To provide information on the development of a gynecologic oncology training program in a low-resource setting in Kenya. This is a review of a collaboration between Kenyan and North American physicians who worked together to develop a gynecologic oncology training in Kenya. We review the published data on the increase of cancer incidence in sub-Saharan Africa and outline the steps that were taken to develop this program. The incidence of cervical cancer in Kenya is very high and is the leading cause of cancer mortality in Kenya...
August 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28801439/validation-of-asthma-recording-in-the-clinical-practice-research-datalink-cprd
#12
Francis Nissen, Daniel R Morales, Hana Mullerova, Liam Smeeth, Ian J Douglas, Jennifer K Quint
OBJECTIVES: The optimal method of identifying people with asthma from electronic health records in primary care is not known. The aim of this study is to determine the positive predictive value (PPV) of different algorithms using clinical codes and prescription data to identify people with asthma in the United Kingdom Clinical Practice Research Datalink (CPRD). METHODS: 684 participants registered with a general practitioner (GP) practice contributing to CPRD between 1 December 2013 and 30 November 2015 were selected according to one of eight predefined potential asthma identification algorithms...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28801407/the-boundaries-of-mild-chronic-obstructive-pulmonary-disease-copd-design-of-the-searching-clinical-copd-onset-soon-study
#13
Gonzalo Labarca, Andrea Bustamante, Gonzalo Valdivia, Rodrigo Díaz, Álvaro Huete, Paul Mac Nab, Laura Mendoza, Jaime Leppe, Carmen Lisboa, Fernando Saldías, Orlando Díaz
INTRODUCTION: Clinical onset of chronic obstructive pulmonary disease (COPD) is the point at which the disease is first identifiable by physicians. It is a poorly defined stage which seems to include both mild spirometric and non-spirometric disease, and could be described as early grade COPD, for practical purposes. While dyspnoea; chronic bronchitis and CT imaging evidence of emphysema and airway disease may be present very early, the lone significance of dyspnoea, the most relevant symptom in COPD in identifying these individuals, has been scarcely assessed...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28798228/technical-peer-review-methods-and-outcomes
#14
Andrew M Keenan, Toni Cranston, Kelsey Hill, Derek J Stocker
Peer review among physicians, nurses and pharmacy staff is routine, yet uncommon in the field of nuclear medicine technology. While not a requirement of regulatory agencies, nuclear medicine technical peer review can greatly enhance the quality of patient care in both hospital and outpatient settings. To date, detailed methods for accomplishing this task have not been previously published. Methods: 19,688 nuclear medicine studies performed at a single institution over a five-year period were critically reviewed...
August 10, 2017: Journal of Nuclear Medicine Technology
https://www.readbyqxmd.com/read/28798015/morbidity-and-mortality-conference-for-percutaneous-coronary-intervention
#15
Jacob A Doll, Robert Overton, Manesh R Patel, Sunil V Rao, Michael H Sketch, J Kevin Harrison, James E Tcheng
BACKGROUND: Morbidity and mortality conference is a common educational and quality improvement activity performed in cardiac catheterization laboratories, but best practices for case selection and for maximizing the effectiveness of peer review have not been determined. METHODS AND RESULTS: We reviewed the 10-year percutaneous coronary intervention morbidity and mortality conference experience of an academic medical center. Cases were triggered for review by the occurrence of prespecified procedural events...
August 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28792572/-the-management-of-depression-in-older-adults-and-their-family-caregivers-findings-from-a-research-program-in-quebec
#16
Jane McCusker, Mark Yaffe, Tamara Sussman, Martin Cole, Maida Sewitch, Erin Strumpf, Ellen Freeman, Sylvie Lambert, Manon de Raad
Objectives A research group based at St. Mary's Research Centre, St. Mary's Hospital, Montreal, has conducted a research program over the past two decades that aims to inform improvements in the management of depression in primary care and general medical settings, among older adults. This paper reviews the findings from this research program, discusses the findings in the context of other research, and highlights the implications for practice and health policy.Methods Narrative review and synthesis of 25 published articles, that included: 4 systematic reviews, 10 observational studies, 9 intervention trials, and 2 consensus conference reports...
2017: Santé Mentale Au Québec
https://www.readbyqxmd.com/read/28782058/consistency-of-brca1-and-brca2-variant-classifications-among-clinical-diagnostic-laboratories
#17
Stephen E Lincoln, Shan Yang, Melissa S Cline, Yuya Kobayashi, Can Zhang, Scott Topper, David Haussler, Benedict Paten, Robert L Nussbaum
BACKGROUND: Genetic tests of the cancer predisposition genes BRCA1 and BRCA2 inform significant clinical decisions for both physicians and patients. Most uncovered variants are benign, and determining which few are pathogenic (disease-causing) is sometimes challenging and can potentially be inconsistent among laboratories. The ClinVar database makes de-identified clinical variant classifications from multiple laboratories publicly available for comparison and review, per recommendations of the American Medical Association (AMA), the American College of Medical Genetics (ACMG), the National Society for Genetic Counselors (NSGC), and other organizations...
July 2017: JCO Precis Oncol
https://www.readbyqxmd.com/read/28780738/john-p-craig-md-mph-physician-scientist-educator-and-mentor-1923-2016
#18
M A Haseeb, Pascal James Imperato
John P. Craig (1923-2016) was an eminent physician-scientist, gifted educator, and greatly valued mentor. Born in West Liberty, Ohio on 29 November 1923, he attended Oberlin College, and received his medical degree from Case Western Reserve University, School of Medicine. This was followed by an internship at Yale University Medical Center, and then service in the U.S. Army during the Korean War. He was a battalion surgeon, preventive medicine officer, and epidemiologist. While in Korea, he conducted important investigations of hemorrhagic fever among American troops...
August 5, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/28768613/medicine-goes-female-protocol-for-improving-career-options-of-females-and-working-conditions-for-researching-physicians-in-clinical-medical-research-by-organizational-transformation-and-participatory-design
#19
Joachim Hasebrook, Klaus Hahnenkamp, Wolfgang F F A Buhre, Dianne de Korte-de Boer, Ankie E W Hamaekers, Bibiana Metelmann, Camila Metelmann, Marina Bortul, Silvia Palmisano, Jannicke Mellin-Olsen, Andrius Macas, Janusz Andres, Anna Prokop-Dorner, Tomáš Vymazal, Juergen Hinkelmann, Sibyll Rodde, Bettina Pfleiderer
BACKGROUND: All European countries need to increase the number of health professionals in the near future. Most efforts have not brought the expected results so far. The current notion is that this is mainly related to the fact that female physicians will clearly outnumber their male colleagues within a few years in nearly all European countries. Still, women are underrepresented in leadership and research positions throughout Europe. OBJECTIVES: The MedGoFem project addresses multiple perspectives with the participation of multiple stakeholders...
August 2, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28768593/staff-nurses-as-antimicrobial-stewards-an-integrative-literature-review
#20
REVIEW
Elizabeth Monsees, Jennifer Goldman, Lori Popejoy
BACKGROUND: Guidelines on antimicrobial stewardship emphasize the importance of an interdisciplinary team, but current practice focuses primarily on defining the role of infectious disease physicians and pharmacists; the role of inpatient staff nurses as antimicrobial stewards is largely unexplored. METHODS: An updated integrative review method guided a systematic appraisal of 13 articles spanning January 2007-June 2016. Quantitative and qualitative peer-reviewed publications including staff nurses and antimicrobial knowledge or stewardship were incorporated into the analysis...
August 1, 2017: American Journal of Infection Control
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