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delayed hyperenhancement

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https://www.readbyqxmd.com/read/27681525/quantitative-assessment-of-washout-in-hepatocellular-carcinoma-using-mri
#1
Roman Kloeckner, Daniel Pinto Dos Santos, Karl-Friedrich Kreitner, Anne Leicher-Düber, Arndt Weinmann, Jens Mittler, Christoph Düber
BACKGROUND: Arterial hyperenhancement and washout on computed tomography and magnetic resonance imaging (MRI) are described by all major guidelines as specific criteria for non-invasive diagnosis of hepatocellular carcinoma (HCC). However, publications on the quantitative assessment of washout in MRI are lacking. Therefore, we evaluated a method for quantitatively measuring and defining washout in MRI in order to determine a cutoff value that allows objective HCC diagnosis. METHODS: We analyzed all patients who underwent liver transplantation for cirrhosis or liver resection for HCC at our institution between 2003 and 2014...
September 29, 2016: BMC Cancer
https://www.readbyqxmd.com/read/27590067/small-intrahepatic-peripheral-cholangiocarcinomas-as-mimics-of-hepatocellular-carcinoma-in-multiphasic-ct
#2
Mishal Mendiratta-Lala, Hakmin Park, Nik Kolicaj, Vivek Mendiratta, Deep Bassi
PURPOSE: Liver transplant guidelines for diagnosing hepatocellular carcinoma (HCC) do not mandate pathologic confirmation; instead, 'classic' imaging features alone are deemed satisfactory. Intrahepatic peripheral mass forming cholangiocarcinoma (IHPMCC) is a relative contraindication for transplantation due to high rate of recurrence and poor prognosis. This study examines the imaging findings of IHPMCC, to aid in the identification and differentiation from potentially confounding cases of HCC...
September 3, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/27414729/focal-fibrosis-and-diffuse-fibrosis-are-predictors-of-reversed-left-ventricular-remodeling-in-patients-with-non-ischemic-cardiomyopathy
#3
Teerapat Yingchoncharoen, Christine Jellis, Zoran B Popovic, Lu Wang, Neville Gai, Wayne C Levy, W H Wilson Tang, Scott Flamm, Deborah H Kwon
BACKGROUND: Prognostic value of myocardial fibrosis in patients with non-ischemic idiopathic dilated cardiomyopathy (DCM) is not well-defined. We sought to assess the association of focal and diffuse myocardial fibrosis with left ventricular reversed remodeling (LVRR). METHODS: Patients with DCM who underwent cardiac MRI with baseline and subsequent follow-up echocardiography were included in the study. Post-contrast T1 times were corrected for renal function, body size, gadolinium dose and time after Gadolinium injection...
October 15, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27249814/acute-myocarditis-with-normal-wall-motion-detected-with-2d-speckle-tracking-echocardiography
#4
Thomas Sturmberger, Johannes Niel, Josef Aichinger, Christian Ebner
UNLABELLED: SummaryWe present the case of a 26-year-old male with acute tonsillitis who was referred for coronary angiography because of chest pain, elevated cardiac biomarkers, and biphasic T waves. The patient had no cardiovascular risk factors. Echocardiography showed no wall motion abnormalities and no pericardial effusion. 2D speckle tracking revealed distinct decreased regional peak longitudinal systolic strain in the lateral and posterior walls. Ischemic disease was extremely unlikely in view of his young age, negative family history regarding coronary artery disease, and lack of regional wall motion abnormalities on the conventional 2D echocardiogram...
March 2016: Echo Research and Practice
https://www.readbyqxmd.com/read/27226026/dynamic-enhancement-patterns-of-intrahepatic-cholangiocarcinoma-in-cirrhosis-on-contrast-enhanced-computed-tomography-risk-of-misdiagnosis-as-hepatocellular-carcinoma
#5
Rui Li, Ping Cai, Kuan-Sheng Ma, Shi-Yi Ding, De-Yu Guo, Xiao-Chu Yan
This study aimed to assess the features of intrahepatic cholangiocarcinoma (ICC) at computerized tomography (CT) and verify the risk of misdiagnosis of ICC as hepatocellular carcinoma (HCC) in cirrhosis. CT appearances of 98 histologically confirmed ICC nodules from 84 cirrhotic patients were retrospectively reviewed, taking into consideration the pattern and dynamic contrast uptake during the arterial, portal venous and delayed phases. During the arterial phase, 53 nodules (54.1%) showed peripheral rim-like enhancement, 35 (35...
2016: Scientific Reports
https://www.readbyqxmd.com/read/26798384/concordant-and-discordant-cardiac-magnetic-resonance-imaging-delayed-hyperenhancement-patterns-in-patients-with-ischemic-and-non-ischemic-cardiomyopathy
#6
Eun Kyoung Kim, Sung-A Chang, Jin-Oh Choi, James Glockner, Brian Shapiro, Yeon Hyeon Choe, Nowell Fine, Shin Yi Jang, Sung-Mok Kim, Wayne Miller, Sang-Chol Lee, Jae K Oh
BACKGROUND AND OBJECTIVES: The diagnosis of ischemic (ICM) and non-ischemic cardiomyopathy (NICM) is conventionally determined by the presence or absence of coronary artery disease (CAD) in the setting of a reduced left systolic function. However the presence of CAD may not always indicate that the actual left ventricular (LV) dysfunction mechanism is ischemia, as other non-ischemic etiologies can be responsible. We investigated patterns of myocardial fibrosis using delayed hyperenhancement (DHE) on cardiac magnetic resonance (CMR) in ICM and NICM...
January 2016: Korean Circulation Journal
https://www.readbyqxmd.com/read/26798220/coronary-microembolization-with-normal-epicardial-coronary-arteries-and-no-visible-infarcts-on-nitrobluetetrazolium-chloride-stained-specimens-evaluation-with-cardiac-magnetic-resonance-imaging-in-a-swine-model
#7
Hang Jin, Hong Yun, Jianying Ma, Zhangwei Chen, Shufu Chang, Mengsu Zeng
OBJECTIVE: To assess magnetic resonance imaging (MRI) features of coronary microembolization in a swine model induced by small-sized microemboli, which may cause microinfarcts invisible to the naked eye. MATERIALS AND METHODS: Eleven pigs underwent intracoronary injection of small-sized microspheres (42 µm) and catheter coronary angiography was obtained before and after microembolization. Cardiac MRI and measurement of cardiac troponin T (cTnT) were performed at baseline, 6 hours, and 1 week after microembolization...
January 2016: Korean Journal of Radiology: Official Journal of the Korean Radiological Society
https://www.readbyqxmd.com/read/26607931/clinical-guideline-seom-hepatocellular-carcinoma
#8
J Sastre, R Díaz-Beveridge, J García-Foncillas, R Guardeño, C López, R Pazo, N Rodriguez-Salas, M Salgado, A Salud, J Feliu
Hepatocellular carcinoma (HCC) represents the second leading cause of cancer-related death worldwide. Surveillance with abdominal ultrasound every 6 months should be offered to patients with a high risk of developing HCC: Child-Pugh A-B cirrhotic patients, all cirrhotic patients on the waiting list for liver transplantation, high-risk HBV chronic hepatitis patients (higher viral load, viral genotype or Asian or African ancestry) and patients with chronic hepatitis C and bridging fibrosis. Accurate diagnosis, staging and functional hepatic reserve are crucial for the optimal therapeutic approach...
December 2015: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/26586554/evaluation-of-liver-metastases-using-contrast-enhanced-ultrasound-enhancement-patterns-and-influencing-factors
#9
Wen-Tao Kong, Zheng-Biao Ji, Wen-Ping Wang, Hao Cai, Bei-Jian Huang, Hong Ding
BACKGROUND/AIMS: To evaluate the enhancement patterns of liver metastases and their influencing factors using dynamic contrast-enhanced ultrasound (CEUS). METHODS: A total of 240 patients (139 male and 101 female; 58.5 ± 11.2 years of age) diagnosed with liver metastases in our hospital were enrolled in this study to evaluate tumor characteristics using CEUS. A comparison of enhancement patterns with tumor size and primary tumor type was performed using the chi-square test...
March 2016: Gut and Liver
https://www.readbyqxmd.com/read/26361889/assessment-of-the-acute-effects-of-glucocorticoid-treatment-on-coronary-microembolization-using-cine-first-pass-perfusion-and-delayed-enhancement-mri
#10
Hang Jin, Hong Yun, Jian-ying Ma, Zhang-wei Chen, Shu-fu Chang, Mei-ying Ge, Meng-su Zeng
PURPOSE: To assess the acute effects of methylprednisone treatment (MPT) on coronary microembolization (CME) by cardiac cine, first-pass perfusion, and delayed gadolinium enhancement magnetic resonance imaging (DE-MRI) in an experimental swine model. MATERIALS AND METHODS: Microembolization was established by intracoronary infusion of microspheres into the left anterior artery. Swine received placebo (n = 12) or methylprednisolone (n = 10, 30 mg/kg) intravenously 30 minutes before microembolization...
April 2016: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/26189273/abnormal-delayed-myocardial-hyperenhancement-on-cardiac-mri-unusual-presentation-of-an-uncommon-diagnosis-cardiac-sarcoidosis
#11
Chete Eze-Nliam, Mandip Gakhal
No abstract text is available yet for this article.
June 2015: Delaware Medical Journal
https://www.readbyqxmd.com/read/26088379/viability-assessment-after-conventional-coronary-angiography-using-a-novel-cardiovascular-interventional-therapeutic-ct-system-comparison-with-gross-morphology-in-a-subacute-infarct-swine-model
#12
Yeonggul Jang, Iksung Cho, Bríain W Ó Hartaigh, Se-Il Park, Youngtaek Hong, Sanghoon Shin, Seongmin Ha, Byunghwan Jeon, Hoyup Jung, Hackjoon Shim, James K Min, Hyuk-Jae Chang, Yangsoo Jang, Namsik Chung
BACKGROUND: Given the lack of promptness and inevitable use of additional contrast agents, the myocardial viability imaging procedures have not been used widely for determining the need to performing revascularization. OBJECTIVE: This study is aimed to evaluate the feasibility of myocardial viability assessment, consecutively with diagnostic invasive coronary angiography (ICA) without use of additional contrast agent, using a novel hybrid system comprising ICA and multislice CT (MSCT)...
July 2015: Journal of Cardiovascular Computed Tomography
https://www.readbyqxmd.com/read/25952572/biphenotypic-hepatic-tumors-imaging-findings-and-review-of-literature
#13
REVIEW
Michael L Wells, Sudhakar K Venkatesh, Vishal S Chandan, Jeff L Fidler, Joel G Fletcher, Geoffrey B Johnson, David M Hough, Lewis R Roberts
PURPOSE: To describe imaging findings in biphenotypic hepatic tumors (BPT) and a proposal for new imaging classification based on contrast-enhanced imaging. METHODS: Retrospective review of CT, MRI, PET/CT, and ultrasound findings in 39 patients with histologically confirmed BPT was performed. Tumor markers including AFP, L3 fraction, CA 19.9, CA 125, and CEA were recorded. Based on the dynamic enhancement features, BPT were categorized into 4 enhancement patterns (Types 1-4)...
October 2015: Abdominal Imaging
https://www.readbyqxmd.com/read/25922775/diagnostic-challenges-in-primary-hepatocellular-carcinoma-case-reports-and-review-of-the-literature
#14
Monika Pazgan-Simon, Sylwia Serafinska, Justyna Janocha-Litwin, Krzysztof Simon, Jolanta Zuwala-Jagiello
Hepatocellular carcinoma is the fifth most common malignancy and the third leading mortality cause worldwide. It typically develops secondarily to liver cirrhosis, due to hepatitis B or C infection, alcohol abuse, metabolic disease, and so forth. According to the American Association for the Study of Liver Diseases (AASLD) guidelines, which constitute diagnostic standards, the diagnosis of primary hepatocellular carcinoma (HCC) should be based on contrast-enhanced imaging. Lesion hyperenhancement should be observed throughout the arterial phase, followed by the washout during the venous phase...
2015: Case Reports in Oncological Medicine
https://www.readbyqxmd.com/read/25921666/imaging-of-hepatocellular-carcinoma-new-approaches-to-diagnosis
#15
REVIEW
Munazza Anis
The currently accepted major diagnostic criteria for identifying hepatocellular carcinoma (HCC) on dynamic cross-sectional imaging consist of diffuse arterial phase hyperenhancement within the lesion, portal venous or delayed phase washout, and the presence and appearance of a capsule; also included in this criteria is interval threshold growth. Ancillary features such as intralesional fat, blood products, and mosaic architecture also favor a diagnosis of HCC. Tumor in a portal or hepatic vein is a definitive finding for an HCC even if a parenchymal mass is not clearly seen...
May 2015: Clinics in Liver Disease
https://www.readbyqxmd.com/read/25916870/differentiation-of-small-arterial-enhancing-hepatocellular-carcinoma-from-non-tumorous-arterioportal-shunt-with-an-emphasis-on-the-precontrast-ct-scan
#16
Bo Mi Chung, Hyun Jeong Park, Sung Bin Park, Jong Beum Lee, Hye Shin Ahn, Yang Soo Kim
PURPOSE: To evaluate the value of precontrast phase (PP) of quadriphasic CT for differentiation of small arterial enhancing hepatocellular carcinoma (HCC) from non-tumorous arterioportal (AP) shunt in patients with chronic liver disease. METHODS: Forty-eight patients with 28 HCCs and 28 AP shunts were enrolled. All lesions (5-20 mm) showed arterial hyperenhancement with isoattenuation on portal venous phase or delayed phase without typical features of AP shunt...
October 2015: Abdominal Imaging
https://www.readbyqxmd.com/read/25904576/quantitative-assessment-of-pericardial-delayed-hyperenhancement-predicts-clinical-improvement-in-patients-with-constrictive-pericarditis-treated-with-anti-inflammatory-therapy
#17
Paul C Cremer, Muhammad U Tariq, Abhishek Karwa, M Chadi Alraies, Rodolfo Benatti, Andres Schuster, Shikhar Agarwal, Scott D Flamm, Deborah H Kwon, Allan L Klein
BACKGROUND: Delayed hyperenhancement (DHE) of the pericardium usually represents ongoing inflammation and may identify patients with constrictive pericarditis that will improve with anti-inflammatory therapy. However, a quantitative assessment of pericardial DHE has not been performed, and the hierarchical relationship among clinical factors, inflammatory markers, and pericardial DHE is unknown. METHODS AND RESULTS: We identified 41 consecutive patients with constrictive pericarditis who had a cardiovascular magnetic resonance study with DHE prior to the initiation of anti-inflammatory medications...
May 2015: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/25832427/collateral-circulation-formation-determines-the-characteristic-profiles-of-contrast-enhanced-mri-in-the-infarcted-myocardium-of-pigs
#18
Jian Wang, Bo Xiang, Hung-yu Lin, Hong-yu Liu, Darren Freed, Rakesh C Arora, Gang-hong Tian
AIM: To investigate the relationship between the collateral circulation and contrast-enhanced MR signal change for myocardial infarction (MI) in pigs. METHODS: Pigs underwent permanent ligation of two diagonal branches of the left anterior descending artery. First-pass perfusion (FPP) MRI (for detecting myocardial perfusion abnormalities) and delayed enhancement (DE) MRI (for estimating myocardial infarction) using Gd-DTPA were performed at 2 h, 7 d and 4 weeks after the coronary occlusion...
April 2015: Acta Pharmacologica Sinica
https://www.readbyqxmd.com/read/25829811/effects-of-high-dose-atorvastatin-pretreatment-in-patients-with-st-segment-elevation-myocardial-infarction-undergoing-primary-percutaneous-coronary-intervention-a-cardiac-magnetic-resonance-study
#19
RANDOMIZED CONTROLLED TRIAL
Eun Kyoung Kim, Joo-Yong Hahn, Young Bin Song, Sung-A Chang, Jin-Ho Choi, Seung-Hyuk Choi, Sang-Chol Lee, Yeon Hyeon Choe, Sang Hoon Lee, Hyeon-Cheol Gwon
It is uncertain that atorvastatin pretreatment can reduce myocardial damage in patients undergoing primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI). The aim of this study was to investigate the effects of atorvastatin pretreatment on infarct size measured by contrast-enhanced magnetic resonance imaging (CE-MRI) in STEMI patients. Patients undergoing primary PCI for STEMI within 12 hr after symptom onset were randomized to an atorvastatin group (n=30, 80 mg before PCI and for 5 days after PCI) or a control group (n=37, 10 mg daily after PCI)...
April 2015: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/25812115/ceus-in-hepatocellular-carcinoma-and-intrahepatic-cholangiocellular-carcinoma-in-320-patients-early-or-late-washout-matters-a-subanalysis-of-the-degum-multicenter-trial
#20
MULTICENTER STUDY
D Wildner, T Bernatik, C Greis, K Seitz, M F Neurath, D Strobel
PURPOSE: The aim of the study was the comparison of tumor vascularization and contrast enhancement in contrast-enhanced ultrasound (CEUS) for the characterization of hepatocellular carcinoma (HCC) and intrahepatic cholangiocellular carcinoma (ICC). We present data of the subpopulations HCC and ICC examined in the DEGUM multicenter trial for the characterization of focal liver lesions in clinical practice. MATERIALS AND METHODS: Based on the data of the DEGUM multicenter trial (1349 patients), all patients with histologically proven HCC (n = 278) and ICC (n = 42) were analyzed...
April 2015: Ultraschall in der Medizin
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