keyword
MENU ▼
Read by QxMD icon Read
search

Obesity paradox

keyword
https://www.readbyqxmd.com/read/29649164/the-impact-of-abdominal-fat-levels-on-all-cause-mortality-risk-in-patients-undergoing-hemodialysis
#1
Takahiro Yajima, Kumiko Yajima, Hiroshi Takahashi, Keigo Yasuda
Although an increased body mass index is associated with lower mortality in patients undergoing hemodialysis (HD), known as the "obesity paradox," the relationship of abdominal fat levels with all-cause mortality has rarely been studied. We investigated the impact of computed-tomography-measured abdominal fat levels (visceral fat area (VFA) and subcutaneous fat area (SFA)) on all-cause mortality in this population. A total of 201 patients undergoing HD were enrolled and cross-classified by VFA and SFA levels according to each cutoff point, VFA of 78...
April 12, 2018: Nutrients
https://www.readbyqxmd.com/read/29642689/the-obestiy-paradox-the-protective-effect-of-obesity-on-right-ventricular-function-using-echocardiographic-strain-imaging-in-patients-with-pulmonary-hypertension
#2
Hiten Patel, Suchit Bhutani, Sahitya Posimreddy, Priyank Shah, Upamanyu Rampal, Apurva Gandhi, Rahul Vasudev, Raja Pullatt, Hartaj Virk, Fayez Shamoon, Mahesh Bikkina, Irvin Goldfarb
BACKGROUND: Obesity is associated withright ventricular (RV) dysfunction, but its effect on RV remodeling in patients with pulmonary hypertension(PHTN) has not been studied. We evaluated the effect of obesity, and its interplay with diabetes, in patients with PHTN using RV echocardiographic strain imaging. METHODS: 185 patients underwent echocardiographic imaging and pulmonary artery pressure was calculated using tricuspid regurgitation jet velocity. From focused RV apical-four-chamber view, global and mid peak systolic RV free wall longitudinal strain (FWLS) wascalculated using speckle-tracking software...
April 11, 2018: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/29622978/obesity-paradox-in-heart-failure-patients-female-gender-characteristics-kamc-single-center-experience
#3
Sheeren Khaled, Rajaa Matahen
Background/Introduction: The correlation between low body mass index (BMI) and congestive heart failure (obesity paradox) has been described in the literature; However, the association between BMI and clinical outcome measures is not well characterized. Little is known about CHF in the Middle Eastern female population; most of the gender-specific information on heart failure comes from higher income "Western" countries. Objectives: We aimed to identify the correlation between heart failure patients especially those with low BMI and clinical/safety outcome measures with focusing on female patients subgroup characteristics...
September 2017: The Egyptian heart journal: (EHJ): official bulletin of the Egyptian Society of Cardiology
https://www.readbyqxmd.com/read/29622509/impact-of-bmi-on-clinical-outcomes-of-noac-therapy-in-daily-care-results-of-the-prospective-dresden-noac-registry-nct01588119
#4
L Tittl, S Endig, S Marten, A Reitter, I Beyer-Westendorf, J Beyer-Westendorf
Direct acting non-Vitamin K antagonist oral anticoagulants (NOAC) are characterized by a fixed dosing regimen. Despite the potential for relative underdosing due to large distribution volumes, dose adjustments for patients with high body mass index (BMI) are not recommended. Since efficacy and safety data in obese patients are scarce, we evaluated the impact of BMI on clinical outcomes in daily care patients treated with NOAC for stroke prevention in atrial fibrillation or venous thromboembolism. Using prospectively collected data from a non-interventional registry, cardiovascular (CV), major bleeding events (MB) and all-cause mortality were evaluated according to BMI classes...
March 14, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29601956/the-impact-of-financial-crisis-in-coronary-artery-disease-burden-in-greece
#5
Elias A Sanidas, Theodoros G Papaioannou, Dimitrios P Papadopoulos, Konstantina Tatsi, Maria Velliou, Nikolaos Dalianis, Ioannis Paizis, George Anastasiadis, Glaukos Kelepesis, Maria Bonou, Kontantinos Tsioufis, John Barbetseas
BACKGROUND: Economic crisis poses an immense threat to public health worldwide and has been linked to cardiovascular morbidity and mortality. Greece is facing a distinctive recession over the recent years. However, the exact impact on coronary artery disease (CAD) burden has not been adequately addressed. METHODS: Demographic, clinical and angiographic data of 3895 hospitalized patients were retrospectively studied. Patients were classified in those before crisis (2006-2007, n=1228) and those during crisis (2011-2015, n=2667)...
March 27, 2018: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/29601397/corr-insights%C3%A2-can-patient-selection-explain-the-obesity-paradox-in-orthopaedic-hip-surgery-an-analysis-of-the-acs-nsqip-registry
#6
James D Slover
No abstract text is available yet for this article.
March 28, 2018: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/29598850/evaluation-of-risk-factors-for-complications-after-bariatric-surgery
#7
D Quilliot, M-A Sirveaux, C Nomine-Criqui, T Fouquet, N Reibel, L Brunaud
The decision to perform a bariatric surgical procedure, the conclusion of a clinical pathway in which management is individually adapted to each patient, is taken after multidisciplinary consultation. Paradoxically, the patients who would most benefit from surgery are also those who have the highest operative risk. In practice, predictive factors of mortality and severe postoperative complications (Clavien-Dindo>III) must be used to evaluate the benefit/risk ratio most objectively. The main risk factors are age, male gender, body mass index, obstructive sleep apnea syndrome, insulin resistance and diabetes, tobacco abuse, cardiovascular disease, ability to lose weight before surgery, hypoalbuminemia and functional disability...
March 26, 2018: Journal of Visceral Surgery
https://www.readbyqxmd.com/read/29598820/the-role-of-obesity-in-carotid-plaque-instability-interaction-with-age-gender-and-cardiovascular-risk-factors
#8
Valentina Rovella, Lucia Anemona, Marina Cardellini, Manuel Scimeca, Andrea Saggini, Giuseppe Santeusanio, Elena Bonanno, Manuela Montanaro, Iacopo Maria Legramante, Arnaldo Ippoliti, Nicola Di Daniele, Massimo Federici, Alessandro Mauriello
BACKGROUND: In the last decade, several studies have reported an unexpected and seemingly paradoxical inverse correlation between BMI and incidence of cardiovascular diseases. This so called "obesity paradox effect" has been mainly investigated through imaging methods instead of histologic evaluation, which is still the best method to study the instability of carotid plaque. Therefore, the purpose of our study was to evaluate by histology the role of obesity in destabilization of carotid plaques and the interaction with age, gender and other major cerebrovascular risk factors...
March 29, 2018: Cardiovascular Diabetology
https://www.readbyqxmd.com/read/29581366/cardiovascular-and-metabolic-heterogeneity-of-obesity-clinical-challenges-and-implications-for-management
#9
REVIEW
Ian J Neeland, Paul Poirier, Jean-Pierre Després
The prevalence of obesity has increased globally over the last 2 decades. Although the body mass index has been a convenient and simple index of obesity at the population level, studies have shown that obesity defined by body mass index alone is a remarkably heterogeneous condition with varying cardiovascular and metabolic manifestations across individuals. Adipose tissue is an exquisitely active metabolic organ engaged in cross-talk between various systems; perturbation of adipose tissue results in a pathological response to positive caloric balance in susceptible individuals that directly and indirectly contributes to cardiovascular and metabolic disease...
March 27, 2018: Circulation
https://www.readbyqxmd.com/read/29579150/dietary-fat-is-a-key-determinant-in-balancing-mitochondrial-dynamics-in-heart-failure-a-novel-mechanism-underlying-the-obesity-paradox
#10
Matteo De Rosa, Jessica Gambardella, Jun Shu, Gaetano Santulli
No abstract text is available yet for this article.
March 22, 2018: Cardiovascular Research
https://www.readbyqxmd.com/read/29570246/the-obesity-paradox-a-misleading-term-that-should-be-abandoned
#11
Katherine M Flegal, John P A Ioannidis
The term "obesity paradox" is a figure of speech, not a scientific term. The term has no precise definition and has been used to describe numerous observations that have little in common other than the finding of an association of obesity with a favorable outcome. The terminology has led to misunderstandings among researchers and the public alike. It's time for authors and editors to abandon the use of this term. Simply labeling counterintuitive findings as the "obesity paradox" adds no value...
April 2018: Obesity
https://www.readbyqxmd.com/read/29566844/associations-of-smoking-physical-inactivity-heavy-drinking-and-obesity-with-quality-adjusted-life-expectancy-among-us-adults-with-depression
#12
Haomiao Jia, Matthew M Zack, Irving I Gottesman, William W Thompson
OBJECTIVES: To examine associations between four health behaviors (smoking, physical inactivity, heavy alcohol drinking, and obesity) and three health indices (health-related quality of life, life expectancy, and quality-adjusted life expectancy (QALE)) among US adults with depression. METHODS: Data were obtained from the 2006, 2008, and 2010 Behavioral Risk Factor Surveillance System data. The EuroQol five-dimensional questionnaire (EQ-5D) health preference scores were estimated on the basis of extrapolations from the Centers for Disease Control and Prevention's healthy days measures...
March 2018: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/29566300/are-the-effects-of-drugs-to-prevent-and-to-treat-heart-failure-always-concordant-the-statin-paradox-and-its-implications-for-understanding-the-actions-of-antidiabetic-medications
#13
REVIEW
Milton Packer
Most treatments for chronic heart failure are effective both in preventing its onset and reducing its progression. However, statins prevent the development of heart failure, but they do not decrease morbidity and mortality in those with established heart failure. This apparent discordance cannot be explained by an effect to prevent interval myocardial infarctions. Instead, it seems that the disease that statins were preventing in trials of patients with a metabolic disorder was different from the disease that they were treating in trials of chronic heart failure...
March 22, 2018: European Journal of Heart Failure
https://www.readbyqxmd.com/read/29550145/impact-of-body-mass-index-on-long-term-outcomes-in-japanese-patients-following-percutaneous-coronary-intervention-the-juntendo-pci-registry
#14
Hirohisa Endo, Tomotaka Dohi, Jun Shitara, Hideki Wada, Shinichiro Doi, Ryo Naito, Hirokazu Konishi, Shuta Tsuboi, Manabu Ogita, Takatoshi Kasai, Shinya Okazaki, Kikuo Isoda, Katsumi Miyauchi, Hiroyuki Daida
BACKGROUND: The prognostic long-term impact of body mass index (BMI) on East Asian patients with coronary artery disease remains unclear. METHODS: An observational retrospective cohort study was carried out involving 3571 patients who had undergone percutaneous coronary intervention (PCI) from 2000 to 2013. Patients were divided into the following five groups according to baseline BMI: Group 1 (underweight 1, BMI ≤20.0kg/m2 ); Group 2 (underweight 2, BMI=20.1-22...
March 14, 2018: Journal of Cardiology
https://www.readbyqxmd.com/read/29511907/cardiovascular-risk-in-patients-with-prehypertension-and-the-metabolic-syndrome
#15
REVIEW
Sergey Kachur, Rebecca Morera, Alban De Schutter, Carl J Lavie
Prehypertension (pHTN) and metabolic syndrome (MetS) are both lifestyle diseases that are potentiated by increased adiposity, as both disease processes are closely related to weight. In the case of pHTN, increased adiposity causes dysregulation of the renin-angiotensin-aldosterone-system (RAAS) as well as adipokine- and leptin-associated increases in adrenergic tone. In MetS, excess weight potentiates hyperglycemia and insulin resistance which causes positive feedback into the RAAS system, activates an inflammatory cascade that potentiates atherosclerosis, and causes lipid dysregulation which together contribute to cardiovascular disease, especially coronary heart disease (CHD) and heart failure (HF)...
March 6, 2018: Current Hypertension Reports
https://www.readbyqxmd.com/read/29510322/paradoxical-role-of-tumor-necrosis-factor-on-metabolic-dysfunction-and-adipose-tissue-expansion-in-mice
#16
Laís Bhering Martins, Marina Chaves de Oliveira, Zélia Menezes-Garcia, Débora Fernandes Rodrigues, Jaqueline Pereira Lana, Leda Quercia Vieira, Mauro Martins Teixeira, Adaliene Versiani Matos Ferreira
OBJECTIVES: Tumor necrosis factor (TNF) is a well-known cytokine that triggers insulin resistance during obesity development. On the other hand, it is also known that TNF induces a fat mass loss during acute diseases. However, whether TNF has a protective and physiological role to control adipose tissue expansion during obesity still needs to be verified. The aim of this study was to evaluate whether the ablation of TNF receptor 1 (TNFR1) alters fat mass and insulin resistance induced by a highly refined carbohydrate-containing (HC) diet...
July 17, 2017: Nutrition
https://www.readbyqxmd.com/read/29502925/high-serum-levels-of-c-reactive-protein-crp-predict-beneficial-decrease-of-visceral-fat-in-obese-females-after-sleeve-gastrectomy
#17
F Carbone, E Nulli Migliola, A Bonaventura, A Vecchié, S De Vuono, M A Ricci, G Vaudo, M Boni, F Dallegri, F Montecucco, G Lupattelli
BACKGROUND & AIMS: Gender-related differences represent an emerging investigation field to better understand obesity heterogeneity and paradoxically associated cardiovascular (CV) risk. Here, we investigated if high-sensitivity C-reactive protein (hs-CRP) might differently affect adiposity and predict the clinical response to bariatric surgery in obese males and females. METHODS AND RESULTS: In 110 morbidly obese patients undergoing laparoscopic sleeve gastrectomy, hs-CRP as well as anthropometric assessment of adiposity, completed by electric bioimpedance and ultrasonography quantification of visceral fat area (VFA), were measured before and one year after surgery...
February 2, 2018: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29501869/pravastatin-improves-risk-factors-but-not-ischaemic-tolerance-in-obese-rats
#18
Massa Oi, Daniel Donner, Jason Peart, Belinda Beck, Lauren Wendt, John P Headrick, Eugene F du Toit
Statins are effective in management of dyslipidaemia, and a cornerstone of CVD prevention strategies. However, the impacts of their pleiotropic effects on other cardiovascular risk factors and myocardial responses to infarction are not well characterised. We hypothesised that pravastatin treatment in obesity improves lipid profiles, insulin-resistance and myocardial resistance to ischaemia/reperfusion (I/R) injury. Wistar rats were fed a control (C) chow or high carbohydrate and fat diet (HCFD) for 16 weeks with vehicle or pravastatin (prava 7...
May 5, 2018: European Journal of Pharmacology
https://www.readbyqxmd.com/read/29497861/obesity-paradox-in-prostate-cancer-increased-body-mass-index-was-associated-with-decreased-risk-of-metastases-after-surgery-in-13-667-patients
#19
Jonas Schiffmann, Pierre I Karakiewicz, Michael Rink, L Manka, Georg Salomon, Derya Tilki, Lars Budäus, Raisa Pompe, Sami-Ramzi Leyh-Bannurah, Alexander Haese, P Hammerer, Hartwig Huland, Markus Graefen, Pierre Tennstedt
INTRODUCTION: Obesity might negatively affect prostate cancer (PCa) outcomes. However, evidence according to the associations between obesity and metastases-free survival after radical prostatectomy (RP) is still inconsistent. METHODS: We relied on PCa patients treated with RP at the Martini-Klinik Prostate Cancer Center between 2004 and 2015. First, multivariable Cox regression analyses examined the impact of obesity on metastases after RP. Last, in a propensity score matched cohort, Kaplan-Meier analyses assessed metastases-free survival according to body mass index (kg/m2 ) (BMI) strata (≥ 30 vs...
March 2, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29492860/the-obesity-paradox-in-cancer-clinical-insights-and-perspectives
#20
Ilaria Trestini, Luisa Carbognin, Clelia Bonaiuto, Giampaolo Tortora, Emilio Bria
A series of evidence demonstrated that obesity represents an established risk factor for an increase in the incidence of multiple cancer types and for poor cancer survival. Nevertheless, recent studies suggested that, in a series of cancers, patients with a normal body mass index (BMI) have worse outcomes than obese patients. This phenomenon, named 'obesity paradox' or 'reverse epidemiology' in cancer, is not well understood and presents controversial aspects. Therefore, this review aims to explore the available studies concerning the relationship between obesity and cancer incidence or survival and to highlight the hypothetical explanations and the methodological framework...
February 28, 2018: Eating and Weight Disorders: EWD
keyword
keyword
31557
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"