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https://www.readbyqxmd.com/read/28181554/analysis-of-influenza-and-rsv-dynamics-in-the-community-using-a-local-transmission-zone-approach
#1
Gal Almogy, Lewi Stone, B Andrei Bernevig, Dana G Wolf, Marina Dorozko, Allon E Moses, Ran Nir-Paz
Understanding the dynamics of pathogen spread within urban areas is critical for the effective prevention and containment of communicable diseases. At these relatively small geographic scales, short-distance interactions and tightly knit sub-networks dominate the dynamics of pathogen transmission; yet, the effective boundaries of these micro-scale groups are generally not known and often ignored. Using clinical test results from hospital admitted patients we analyze the spatio-temporal distribution of Influenza Like Illness (ILI) in the city of Jerusalem over a period of three winter seasons...
February 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28165168/blooming-knit-flowers-loop-linked-soft-morphing-structures-for-soft-robotics
#2
Min-Woo Han, Sung-Hoon Ahn
A loop-linked structure, which is capable of morphing in various modes, including volumetric transformation, is developed based on knitting methods. Morphing flowers (a lily-like, a daffodil-like, gamopetalous, and a calla-like flower) are fabricated using loop patterning, and their blooming motion is demonstrated by controlling a current that selectively actuates the flowers petals.
February 6, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28161684/silk-based-anisotropical-3d-biotextiles-for-bone-regeneration
#3
Viviana P Ribeiro, Joana Silva-Correia, Ana I Nascimento, Alain da Silva Morais, Alexandra P Marques, Ana S Ribeiro, Carla J Silva, Graça Bonifácio, Rui A Sousa, Joaquim M Oliveira, Ana L Oliveira, Rui L Reis
Bone loss in the craniofacial complex can been treated using several conventional therapeutic strategies that face many obstacles and limitations. In this work, novel three-dimensional (3D) biotextile architectures were developed as a possible strategy for flat bone regeneration applications. As a fully automated processing route, this strategy as potential to be easily industrialized. Silk fibroin (SF) yarns were processed into weft-knitted fabrics spaced by a monofilament of polyethylene terephthalate (PET)...
January 26, 2017: Biomaterials
https://www.readbyqxmd.com/read/28154746/bone-ingrowth-to-ti-fibre-knit-block-with-high-deformability
#4
Yoko Henmi, Yoshihito Naito, Ryo Jimbo, Yohei Jinno, Kazumitsu Sekine, Kenichi Hamada
OBJECTIVES: The objective of this study is to develop a Ti fibre knit block without sintering, and to evaluate its deformability and new bone formation in vivo. MATERIAL AND METHODS: A Ti fibre with a diameter of 150 μm was knitted to fabricate a Ti mesh tube. The mesh tube was compressed in a metal mould to fabricate porous Ti fibre knit blocks with three different porosities of 88%, 69%, and 50%. The elastic modulus and deformability were evaluated using a compression test...
October 2016: Journal of Oral & Maxillofacial Research
https://www.readbyqxmd.com/read/28145041/first-in-human-experience-of-a-new-self-expandable-percutaneous-pulmonary-valve-implantation-using-knitted-nitinol-wire-and-tri-leaflet-porcine-pericardial-valve-in-the-native-right-ventricular-outflow-tract
#5
Gi Beom Kim, Bo Sang Kwon, Hong Gook Lim
Balloon-expandable percutaneous pulmonary valve systems using the Melody and Edwards SAPIEN transcatheter heart valves have been increasingly used instead of surgically implantable pulmonary valves. However, limited patients with right ventricular outflow tract (RVOT) lesions are suitable candidates for percutaneous pulmonary valve implantation (PPVI) using these systems after surgical correction of tetralogy of Fallot. Therefore, larger self-expandable valved-stents are being developed for native RVOT lesions...
February 1, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28138542/knitting-and-weaving-artificial-muscles
#6
Ali Maziz, Alessandro Concas, Alexandre Khaldi, Jonas Stålhand, Nils-Krister Persson, Edwin W H Jager
A need exists for artificial muscles that are silent, soft, and compliant, with performance characteristics similar to those of skeletal muscle, enabling natural interaction of assistive devices with humans. By combining one of humankind's oldest technologies, textile processing, with electroactive polymers, we demonstrate here the feasibility of wearable, soft artificial muscles made by weaving and knitting, with tunable force and strain. These textile actuators were produced from cellulose yarns assembled into fabrics and coated with conducting polymers using a metal-free deposition...
January 2017: Science Advances
https://www.readbyqxmd.com/read/28138014/loose-knit-family-tracing-the-evolution-of-actin-depolymerizing-factors-that-sever-or-join-the-actin-cytoskeleton
#7
Jennifer A Lockhart
No abstract text is available yet for this article.
January 30, 2017: Plant Cell
https://www.readbyqxmd.com/read/28120754/-biodegradable-synthetic-polymers-for-the-design-of-implantable-medical-devices-the-ligamentoplasty-case
#8
Xavier Garric, Benjamin Nottelet, Coline Pinese, Adrien Leroy, Jean Coudane
The sector of implantable medical devices is a growing sector of health products especially dynamic in the field of research. To improve the management of patients and to meet clinical requirements, researchers are developing new types of medical devices. They use different families of biomaterials presenting various chemical and physical characteristics in order for providing clinicians with health products optimized for biomedical applications. In this article, we aim to show how, starting from a family of biomaterials (degradable polymers), it is possible to design an implantable medical device for the therapeutic management of the failure of anterior cruciate ligament...
January 2017: Médecine Sciences: M/S
https://www.readbyqxmd.com/read/28114035/battery-free-smart-sock-for-abnormal-relative-plantar-pressure-monitoring
#9
Xiaoyou Lin, Boon-Chong Seet
This paper presents a new design of a wearable plantar pressure monitoring system in the form of a smart sock for sensing abnormal relative pressure changes. One advantage of this approach is that with a battery-free design, this system can be powered solely by radio frequency (RF) energy harvested from a radio frequency identification (RFID) reader unit hosted on a smartphone of the wearer. At the same time, this RFID reader can read foot pressure values from an embedded sensor-tag in the sock. A pressure sensing matrix made of conductive fabric and flexible piezo-resistive material is integrated into the sock during the knitting process...
December 5, 2016: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/28109388/penetrating-trauma-of-the-thoracic-aorta-caused-by-a-knitting-needle
#10
Alessandro Tamburrini, Syed M Rehman, Daniela Votano, Pietro G Malvindi, Ian Nordon, Robert Allison, Szabolcs Miskolczi
No abstract text is available yet for this article.
February 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28098192/wearable-atmospheric-pressure-plasma-fabrics-produced-by-knitting-flexible-wire-electrodes-for-the-decontamination-of-chemical-warfare-agents
#11
Heesoo Jung, Jin Ah Seo, Seungki Choi
One of the key reasons for the limited use of atmospheric pressure plasma (APP) is its inability to treat non-flat, three-dimensional (3D) surface structures, such as electronic devices and the human body, because of the rigid electrode structure required. In this study, a new APP system design-wearable APP (WAPP)-that utilizes a knitting technique to assemble flexible co-axial wire electrodes into a large-area plasma fabric is presented. The WAPP device operates in ambient air with a fully enclosed power electrode and grounded outer electrode...
January 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28093363/alignment-of-collagen-fiber-in-knitted-silk-scaffold-for-functional-massive-rotator-cuff-repair
#12
Zefeng Zheng, Jisheng Ran, Weishan Chen, Yejun Hu, Ting Zhu, Xiao Chen, Zi Yin, Boon Chin Heng, Gang Feng, Huihui Le, Chenqi Tang, Jiayun Huang, Yangwu Chen, Yiting Zhou, Pioletti Dominique, Weiliang Shen, Hong-Wei Ouyang
: Rotator cuff tear is one of the most common types of shoulder injuries, often resulting in pain and physical debilitation. Allogeneic tendon-derived decellularized matrices do not have appropriate pore size and porosity to facilitate cell infiltration, while commercially-available synthetic scaffolds are often inadequate at inducing tenogenic differentiation. The aim of this study is to develop an advanced 3D aligned collagen/silk scaffold (ACS) and investigate its efficacy in a rabbit massive rotator cuff tear model...
January 13, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28088344/design-control-considerations-for-biologic-device-combination-products
#13
Dave Anderson, Roger Liu, J Anand Subramony, Jon Cammack
Combination products are therapeutic and diagnostic medical products that combine drugs, devices, and/or biological products with one another. Historically, biologics development involved identifying efficacious doses administered to patients intravenously or perhaps by a syringe. Until fairly recently, there has been limited focus on developing an accompanying medical device, such as a prefilled syringe or auto-injector, to enable easy and more efficient delivery. For the last several years, and looking forward, where there may be little to distinguish biologics medicines with relatively similar efficacy profiles, the biotechnology market is beginning to differentiate products by patient-focused, biologic-device based combination products...
January 11, 2017: Advanced Drug Delivery Reviews
https://www.readbyqxmd.com/read/28049476/an-improved-extraction-method-for-surface-dosage-of-insecticides-on-treated-textile-fabrics
#14
Florence Dieval, Jérémy Bouyer, Jean-François Fafet
BACKGROUND: Tens of millions of people live in mosquito-infested regions and controlling mosquito-borne diseases is one of the major interventions aimed at alleviating poverty worldwide. The use of insecticide-treated textiles is one of the most widespread control measures. This includes bed nets, battle clothing or, more generally, textiles use for clothing. These textiles are generally treated with permethrin as active ingredient, which is dosed after extraction of the active molecule present throughout the fabric (measured in mg permethrin/g of fabric) and does not take the effective concentration on the textile surfaces into account...
January 4, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28038405/comprehensive-mechanical-characterization-of-pla-fabric-combined-with-pcl-to-form-a-composite-structure-vascular-graft
#15
Chaojing Li, Fujun Wang, Graeham Douglas, Ze Zhang, Robert Guidoin, Lu Wang
Vascular grafts made by tissue engineering processes are prone to buckling and twisting, which can impede blood flow and lead to collapse of the vessel. These vascular conduits may suffer not only from insufficient tensile strength, but also from vulnerabilities related to compression, torsion, and pulsatile pressurization. Aiming to develop a tissue engineering-inspired blood conduit, composite vascular graft (cVG) prototypes were created by combining a flexible polylactic acid (PLA) knitted fabric with a soft polycaprolactone (PCL) matrix...
December 15, 2016: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28034577/10-lessons-learned-by-a-misguided-physician
#16
REVIEW
Barry E Levin
It was a great and humbling honor to receive the 2016 Distinguished Career Award from my SSIB colleagues. This paper summarizes the major points of my DCA talk at the 2016 annual meeting. It is a reflection on my 50year medical and research career and 10 lessons I have learned over those years which might be of help to young investigators near the beginning of their own research careers. These lessons include: the value of being receptive to the opportunities provided you; how clinician-scientists can serve as critical role models for young investigators like me and a history of how my career developed as a result of their influence; the importance of carefully examining your own data, particularly when it doesn't agree with your preconceived ideas; the critical role that students, postdocs and PhD (and even veterinarian) colleagues can play in developing one's career; the likelihood that your career path will have many interesting twists and turns determined by changes in your own scientific interests and how rewarding various areas of research focus are to you; the importance of building a close-knit laboratory staff family; the fact that science and romance can mix...
December 26, 2016: Physiology & Behavior
https://www.readbyqxmd.com/read/28028595/comprehensive-two-dimensional-gas-chromatographic-profiling-and-chemometric-interpretation-of-the-volatile-profiles-of-sweat-in-knit-fabrics
#17
A Paulina de la Mata, Rachel H McQueen, Seo Lin Nam, James J Harynuk
Human axillary sweat is a poorly explored biofluid within the context of metabolomics when compared to other fluids such as blood and urine. In this paper, we explore the volatile organic compounds emitted from two different types of fabric samples (cotton and polyester) which had been worn repeatedly during exercise by participants. Headspace solid-phase microextraction (SPME) and comprehensive two-dimensional gas chromatography time-of-flight mass spectrometry (GC×GC-TOFMS) were employed to profile the (semi)volatile compounds on the fabric...
March 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28028520/evaluation-of-structural-and-mechanical-properties-of-electrospun-nano-micro-hybrid-of-poly-hydroxybutyrate-chitosan-silk-scaffold-for-cartilage-tissue-engineering
#18
Saeed Karbasi, Farnoosh Fekrat, Daryoush Semnani, Shahnaz Razavi, Elham Naghash Zargar
BACKGROUND: One of the new methods of scaffold fabrication is a nano-micro hybrid structure in which the properties of the scaffold are improved by introducing nanometer and micrometer structures. This method could be suitable for scaffold designing if some features improve. MATERIALS AND METHODS: In this study, electrospun nanofibers of 9% weight solution of poly (3-hydroxybutyrate) (P3HB) and a 15% weight of chitosan by trifluoroacetic acid were coated on both the surface of a silk knitted substrate in the optimum condition to improve the mechanical properties of scaffolds for cartilage tissue engineering application...
2016: Advanced Biomedical Research
https://www.readbyqxmd.com/read/28027084/caring-for-the-amish-what-every-anesthesiologist-should-know
#19
Gregory E R Weller
The Amish are a relatively isolated group with cultural and religious customs that differ significantly from the mainstream American population. Functioning as tight-knit communities with strong conservative Christian beliefs, the Amish maintain a culture based on intentional separateness from the outside world. Key aspects of Amish life include distinct clothing and behaviors, a unique language, an agrarian lifestyle, limited formal education, nonviolence/nonaggression, and a general lack of modern technology, as exemplified by the use of the traditional horse-and-buggy...
December 22, 2016: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/27999810/development-of-a-new-hybrid-biodegradable-drug-eluting-stent-for-the-treatment-of-peripheral-artery-disease
#20
Jung-Hee Lee, Soon-Joong Kim, Se-Il Park, Young-Guk Ko, Donghoon Choi, Myeong-Ki Hong, Yangsoo Jang
This study aimed to develop a new biodegradable stent for peripheral artery disease (PAD) that could provide sufficient radial force to maintain long-term patency and flexibility. All self-expandable hybrid biodegradable stents were designed by using a knitting structure composed of poly-L-lactic acid (PLLA) and nitinol. Four different types of stents were implanted in 20 iliac arteries in 10 mini pigs as follows: a bare-metal stent (BMS) (group 1, n = 5), a drug-free hybrid stent (group 2, n = 5), a 50% (50 : 100, w/w) paclitaxel (PTX)/poly-lactide-co-glycolic acid (PLGA; fast PTX-releasing form) hybrid stent (group 3, n = 5), and a 30% (30 : 100, w/w) PTX/PLGA (slow PTX-releasing form) hybrid stent (group 4, n = 5)...
2016: BioMed Research International
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