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https://www.readbyqxmd.com/read/28223989/ufgt-the-key-enzyme-associated-with-the-petals-variegation-in-japanese-apricot
#1
Xinxin Wu, Qinghua Gong, Xiaopeng Ni, Yong Zhou, Zhihong Gao
Japanese apricot (Prunus mume Sieb.et Zucc.) is an important ornamental plant in China. One of the traits of petals color variegation is attractive, but its formation mechanism is unclear. In our study, RNA-seq technology was employed to characterize the transcriptome response to the mutation of "Fuban Tiaozhi" associated with petals variegation in Japanese apricot. As a result, 4,579,040 (white-flowered, WF) and 7,269,883 (red-flowered, RF) reads were mapped to P. persica genes, while 5,006,676 (WF) and 7,907,436 (RF) were mapped to P...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28205333/longitudinal-study-of-clinical-prognostic-factors-in-patients-with-early-rheumatoid-arthritis-the-predict-study
#2
Paul Bird, Dave Nicholls, Rina Barrett, Julien de Jager, Hedley Griffiths, Lynden Roberts, Kathleen Tymms, Philip McCloud, Geoffrey Littlejohn
AIM: To assess the association between baseline clinical prognostic factors and subsequent Disease Activity Score of 28 joints (DAS28) remission in early rheumatoid arthritis (RA). METHODS: Data were collected using point of care clinical software from participating rheumatology centres. Patients aged 18 years or over whose date of clinical onset of RA was within the previous 12-24 months, who had at least 6 months of follow-up data and a DAS28-ESR (erythrocyte sedimentation rate) score recorded between 12 and 24 months from first being seen for RA were included...
February 16, 2017: International Journal of Rheumatic Diseases
https://www.readbyqxmd.com/read/28203122/evaluation-of-the-effect-of-radiofrequency-radiation-emitted-from-wi-fi-router-and-mobile-phone-simulator-on-the-antibacterial-susceptibility-of-pathogenic-bacteria-listeria-monocytogenes-and-escherichia-coli
#3
M Taheri, S M J Mortazavi, M Moradi, S Mansouri, G R Hatam, F Nouri
Mobile phones and Wi-Fi radiofrequency radiation are among the main sources of the exposure of the general population to radiofrequency electromagnetic fields (RF-EMF). Previous studies have shown that exposure of microorganisms to RF-EMFs can be associated with a wide spectrum of changes ranged from the modified bacterial growth to the alterations of the pattern of antibiotic resistance. Our laboratory at the nonionizing department of the Ionizing and Non-ionizing Radiation Protection Research Center has performed experiments on the health effects of exposure to animal models and humans to different sources of electromagnetic fields such as cellular phones, mobile base stations, mobile phone jammers, laptop computers, radars, dentistry cavitrons, magnetic resonance imaging, and Helmholtz coils...
January 2017: Dose-response: a Publication of International Hormesis Society
https://www.readbyqxmd.com/read/28197823/the-deposition-of-strontium-and-zinc-co-substituted-hydroxyapatite-coatings
#4
L Robinson, K Salma-Ancane, L Stipniece, B J Meenan, A R Boyd
The in vitro and in vivo performance of hydroxyapatite (HAp) coatings can be modified by the addition of different trace ions, such as silicon (Si), lithium (Li), magnesium (Mg), zinc (Zn) or strontium (Sr) into the HAp lattice, to more closely mirror the complex chemistry of human bone. To date, most of the work in the literature has considered single ion-substituted materials and coatings, with limited reports on co-substituted calcium phosphate systems. The aim of this study was to investigate the potential of radio frequency magnetron sputtering to deposit Sr and Zn co-substituted HAp coatings using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS)...
March 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28191607/retrospective-study-of-the-clinical-characteristics-and-risk-factors-of-rheumatoid-arthritis-associated-interstitial-lung-disease
#5
Yongfeng Zhang, Hongbin Li, Nawei Wu, Xin Dong, Yi Zheng
This study aims to explore the clinical characteristics and risk factors of rheumatoid arthritis (RA)-associated interstitial lung disease (ILD). This is a retrospective study of 550 patients with RA. All patients underwent chest high-resolution computed tomography (HRCT) scanning. (1) Two hundred thirty-seven out of five hundred fifty (43.1%) patients with RA were diagnose with ILD. 13.5% ILD occurred before RA onset, 69.6% ILD occurred within 10 years of RA onset, and 16.9% ILD occurred more than 10 years after RA onset...
February 12, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28129184/multi-polarization-reconfigurable-antenna-for-wireless-biomedical-system
#6
Hang Wong, Wei Lin, Laure Huitema, Eric Arnaud
This paper presents a multi-polarization reconfigurable antenna with four dipole radiators for biomedical applications in body-centric wireless communication system (BWCS). The proposed multi-dipole antenna with switchable 0°, +45°, 90° and -45° linear polarizations is able to overcome the polarization mismatching and multi-path distortion in complex wireless channels as in BWCS. To realize this reconfigurable feature for the first time among all the reported antenna designs, we assembled four dipoles together with 45° rotated sequential arrangements...
January 23, 2017: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/28121998/rheumatic-heart-disease-and-myxomatous-degeneration-differences-and-similarities-of-valve-damage-resulting-from-autoimmune-reactions-and-matrix-disorganization
#7
Carlo de Oliveira Martins, Lea Demarchi, Frederico Moraes Ferreira, Pablo Maria Alberto Pomerantzeff, Carlos Brandao, Roney Orismar Sampaio, Guilherme Sobreira Spina, Jorge Kalil, Edecio Cunha-Neto, Luiza Guilherme
Autoimmune inflammatory reactions leading to rheumatic fever (RF) and rheumatic heart disease (RHD) result from untreated Streptococcus pyogenes throat infections in individuals who exhibit genetic susceptibility. Immune effector mechanisms have been described that lead to heart tissue damage culminating in mitral and aortic valve dysfunctions. In myxomatous valve degeneration (MXD), the mitral valve is also damaged due to non-inflammatory mechanisms. Both diseases are characterized by structural valve disarray and a previous proteomic analysis of them has disclosed a distinct profile of matrix/structural proteins differentially expressed...
2017: PloS One
https://www.readbyqxmd.com/read/28113068/symptoms-and-the-use-of-wireless-communication-devices-a-prospective-cohort-study-in-swiss-adolescents
#8
Anna Schoeni, Katharina Roser, Martin Röösli
BACKGROUND: We investigated whether radiofrequency electromagnetic fields (RF-EMF) from mobile phones and other wireless devices or by the wireless device use itself due to non-radiation related factors in that context are associated with an increase in health symptom reports of adolescents in Central Switzerland. METHODS: In a prospective cohort study, 439 study participants (participation rate: 36.8%) aged 12-17 years, completed questionnaires about their mobile and cordless phone use, their self-reported symptoms and possible confounding factors at baseline (2012/2013) and one year later (2013/2014)...
January 20, 2017: Environmental Research
https://www.readbyqxmd.com/read/28046877/th-ef-bra-06-a-novel-retrospective-3d-k-space-sorting-4d-mri-technique-using-a-radial-k-space-acquisition-mri-sequence
#9
Y Liu, E Subashi, F Yin, J Cai
PURPOSE: Current retrospective 4D-MRI provides superior tumor-to-tissue contrast and accurate respiratory motion information for radiotherapy motion management. The developed 4D-MRI techniques based on 2D-MRI image sorting require a high frame-rate of the MR sequences. However, several MRI sequences provide excellent image quality but have low frame-rate. This study aims at developing a novel retrospective 3D k-space sorting 4D-MRI technique using radial k-space acquisition MRI sequences to improve 4D-MRI image quality and temporal-resolution for imaging irregular organ/tumor respiratory motion...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28046655/su-f-t-169-a-periodic-quality-assurance-program-for-a-spot-scanning-proton-treatment-facility
#10
D Mundy, E Tryggestad, C Beltran, K Furutani, G Gilson, S Ito, J Johnson, J Kruse, N Remmes, A Tasson, T Whitaker, M Herman
PURPOSE: To develop daily and monthly quality assurance (QA) programs in support of a new spot-scanning proton treatment facility using a combination of commercial and custom equipment and software. Emphasis was placed on efficiency and evaluation of key quality parameters. METHODS: The daily QA program was developed to test output, spot size and position, proton beam energy, and image guidance using the Sun Nuclear Corporation rf-DQA™3 device and Atlas QA software...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28030898/early-hypopharyngeal-cancer-treated-with-different-therapeutic-approaches-a-single-institution-cohort-analysis
#11
Nalee Kim, Jeongshim Lee, Kyung Hwan Kim, Jong Won Park, Chang Geol Lee, Ki Chang Keum
PURPOSE: Early hypopharyngeal squamous cell carcinoma (HPSCC) is a rarely diagnosed disease, for which the optimal treatment has not been defined yet. We assessed patterns of failure and outcomes in early HPSCC treated with various therapeutic approaches to identify its optimal treatment. MATERIALS AND METHODS: Thirty-six patients with stage I (n = 10) and II (n = 26) treated between January 1992 and March 2014 were reviewed. Patients received definitive radiotherapy (RT) (R group, n = 10), surgery only (S group, n = 19), or postoperative RT (PORT group, n = 7)...
December 2016: Radiation Oncology Journal
https://www.readbyqxmd.com/read/28019022/use-of-pattern-recognition-for-unaliasing-simultaneously-acquired-slices-in-simultaneous-multislice-mr-fingerprinting
#12
Yun Jiang, Dan Ma, Himanshu Bhat, Huihui Ye, Stephen F Cauley, Lawrence L Wald, Kawin Setsompop, Mark A Griswold
PURPOSE: The purpose of this study is to accelerate an MR fingerprinting (MRF) acquisition by using a simultaneous multislice method. METHODS: A multiband radiofrequency (RF) pulse was designed to excite two slices with different flip angles and phases. The signals of two slices were driven to be as orthogonal as possible. The mixed and undersampled MRF signal was matched to two dictionaries to retrieve T1 and T2 maps of each slice. Quantitative results from the proposed method were validated with the gold-standard spin echo methods in a phantom...
December 26, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28003802/restricted-feeding-schedules-modulate-in-a-different-manner-the-expression-of-clock-genes-in-rat-hypothalamic-nuclei
#13
Leonardo D De Araujo, Silvia L Roa, Ana C Bueno, Fernanda B Coeli-Lacchini, Clarissa S Martins, Ernane T Uchoa, Jose Antunes-Rodrigues, Lucila L Elias, Paula C Elias, Ayrton C Moreira, Margaret De Castro
Food access restriction is associated to changes in gene expression of the circadian clock system. However, there are only a few studies investigating the effects of non-photic synchronizers, such as food entrainment, on the expression of clock genes in the central oscillators. We hypothesized that different feeding restriction patterns could modulate the expression of clock genes in the suprachiasmatic nucleus (SCN) "master" clock and in extra-SCN oscillators such as the paraventricular (PVN) and arcuate (ARC) hypothalamic nuclei...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27989463/coupling-between-one-dimensional-networks-reconciles-conflicting-dynamics-in-lip-and-reveals-its-recurrent-circuitry
#14
Wujie Zhang, Annegret L Falkner, B Suresh Krishna, Michael E Goldberg, Kenneth D Miller
Little is known about the internal circuitry of the primate lateral intraparietal area (LIP). During two versions of a delayed-saccade task, we found radically different network dynamics beneath similar population average firing patterns. When neurons are not influenced by stimuli outside their receptive fields (RFs), dynamics of the high-dimensional LIP network during slowly varying activity lie predominantly in one multi-neuronal dimension, as described previously. However, when activity is suppressed by stimuli outside the RF, slow LIP dynamics markedly deviate from a single dimension...
January 4, 2017: Neuron
https://www.readbyqxmd.com/read/27986837/greater-v%C3%AB-o2peak-is-correlated-with-greater-skeletal-muscle-deoxygenation-amplitude-and-hemoglobin-concentration-within-individual-muscles-during-ramp-incremental-cycle-exercise
#15
Dai Okushima, David C Poole, Thomas J Barstow, Harry B Rossiter, Narihiko Kondo, T Scott Bowen, Tatsuro Amano, Shunsaku Koga
It is axiomatic that greater aerobic fitness (V˙O2peak) derives from enhanced perfusive and diffusive O2 conductances across active muscles. However, it remains unknown how these conductances might be reflected by regional differences in fractional O2 extraction (i.e., deoxy [Hb+Mb] and tissue O2 saturation [StO2]) and diffusive O2 potential (i.e., total[Hb+Mb]) among muscles spatially heterogeneous in blood flow, fiber type, and recruitment (vastus lateralis, VL; rectus femoris, RF). Using quantitative time-resolved near-infrared spectroscopy during ramp cycling in 24 young participants (V˙O2peak range: ~37...
December 2016: Physiological Reports
https://www.readbyqxmd.com/read/27942891/recurrent-oropharyngeal-cancer-after-organ-preserving-treatment-pattern-of-failure-and-survival
#16
M de Ridder, Z A R Gouw, J J Sonke, A Navran, B Jasperse, J Heukelom, M E T Tesselaar, W M C Klop, M W M van den Brekel, Abrahim Al-Mamgani
The objectives is to thoroughly analyze the pattern of failure and oncologic outcome in recurrent oropharyngeal cancer (OPC) after (chemo)radiotherapy and correlate the site of failure to the planned radiation dose. Between January 2010 and April 2014, 57 patients with recurrent OPC after (chemo)radiotherapy were analyzed. Endpoints were pattern of failure and overall survival (OS). Local (LF) and regional failure (RF) were classified as in-field [>50% within gross tumor volume (GTV)], marginal [<50% within GTV but >50% within clinical target volume (CTV)], or out-of-field (>50% outside CTV) recurrences...
December 9, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27939434/reconstruction-of-randomly-under-sampled-spectra-for-in-vivo-13-c-magnetic-resonance-spectroscopy
#17
Ningzhi Li, Shizhe Li, Jun Shen
PURPOSE: Over the past decade, many techniques have been developed to reduce radiofrequency (RF) power deposition associated with proton decoupling in in vivo Carbon-13 ((13)C) magnetic resonance spectroscopy (MRS). In this work we propose a new strategy that uses data under-sampling to achieve reduction in RF power deposition. MATERIALS AND METHODS: Essentially, proton decoupling is required only during randomly selected segments of data acquisition. By taking advantage of the sparse spectral pattern of the carboxylic/amide region of in vivo(13)C spectra of brain, we developed an iterative algorithm to reconstruct spectra from randomly under-sampled data...
December 7, 2016: Magnetic Resonance Imaging
https://www.readbyqxmd.com/read/27916374/transfer-and-priming-of-surgical-skills-across-minimally-invasive-surgical-platforms
#18
Ahmed Zihni, Tianjia Ge, Shuddhadeb Ray, Robert Wang, Zhe Liang, Jaime A Cavallo, Michael M Awad
BACKGROUND: Robot-assisted laparoscopic surgery (RALS) uses 3-dimensional visualization and wristed instruments that provide more degrees of freedom than rigid traditional laparoscopic (TLS) instrumentation. These features have been touted to improve accuracy and efficiency during surgical task performance. Little is known, however, about the transferability of skills between the two platforms or whether task performance on one platform primes surgeons for task performance on the other...
November 2016: Journal of Surgical Research
https://www.readbyqxmd.com/read/27874271/diagnostic-model-generated-by-mri-derived-brain-features-in-toddlers-with-autism-spectrum-disorder
#19
Xiang Xiao, Hui Fang, Jiansheng Wu, ChaoYong Xiao, Ting Xiao, Lu Qian, FengJing Liang, Zhou Xiao, Kang Kang Chu, Xiaoyan Ke
Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with core symptoms of atypical social interaction, communication, and restricted, repetitive patterns of behavior, interests, and activities. Although the pathophysiologic mechanism of ASD is unclarified yet, the neuroanatomical features are considered as valuable predictors for discriminating ASD from others. But there has been relatively little scientific study about predictive power of different neuroanatomical features of early age ASD...
November 22, 2016: Autism Research: Official Journal of the International Society for Autism Research
https://www.readbyqxmd.com/read/27855311/effect-of-aging-on-regional-neuromuscular-regulation-within-human-rectus-femoris-muscle-during-stair-ascent-and-descent
#20
Kohei Watanabe, Motoki Kouzaki, Toshio Moritani
Our recent studies showed the rectus femoris (RF) muscle is regionally regulated during the level walking and this unique neuromuscular activation pattern is influenced by aging (Watanabe et al., 2014, 2016 J Biomech). We aimed to investigate and compare regional neuromuscular activation patterns along the RF muscle between the young and elderly during the stair walking. Fourteen young men (age: 20.4±1.0years) and 14 elderly men (age: 73.8±5.9years) performed the stair ascent and descent. Fifteen trials of three steps were performed for both stair ascent and descent...
November 10, 2016: Gait & Posture
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