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https://www.readbyqxmd.com/read/28813608/hot-air-treatment-induces-disease-resistance-through-activating-the-phenylpropanoid-metabolism-in-cherry-tomato-fruit
#1
Yingying Wei, Dandan Zhou, Jing Peng, Leiqing Pan, Kang Tu
To explore the effects of hot air (HA, 38 °C for 12 h) treatment on phenylpropanoid metabolism in cherry tomatoes, phenylpropanoid metabolite levels and the activities and expression of key enzymes were analyzed in HA-treated fruit. HA treatment enhanced phenylpropanoid metabolism, as evidenced by elevated levels of phenolics and flavonoids, higher activities of phenylalanine ammonia-lyase and cinnamate-4-hydroxylase, and up-regulated expression of LeCHS, LeCHI, LeF3H, and LeFLS. Levels of several phenylpropanoid metabolites were higher after HA treatment, including p-coumaric acid, caffeic acid, chlorogenic acid, isoquercitrin, quercetin, and rutin...
August 16, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28812354/3d-moldable-nanofiber-reinforced-transparent-composites-with-hierarchically-self-assembled-reverse-nacre-like-architecture
#2
Subir Kumar Biswas, Hironari Sano, Md Iftekhar Shams, Hiroyuki Yano
Achieving structural hierarchy and a uniform nanofiller dispersion simultaneously remains highly challenging for obtaining a robust polymer nanocomposite of immiscible components. In this study, a remarkably facile Pickering emulsification approach is developed to fabricate hierarchical composites of immiscible acrylic polymer and native cellulose nanofibers by taking advantage of the dual role of the nanofibers as both the emulsion stabilizer and polymer reinforcement. The composites feature a unique "reverse" nacre-like microstructure reinforced with well-dispersed two-tier hierarchical nanofiber network, leading to a synergistic high strength, modulus, and toughness (20, 50, and 53 times that of neat polymer, respectively), high optical transparency (89%), high flexibility and a drastically low thermal expansion (13 ppm/K, 1/15th of the neat polymer)...
August 16, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28812182/rheological-characterization-of-molten-polymer-drug-dispersions-as-a-predictive-tool-for-pharmaceutical-hot-melt-extrusion-processability
#3
Jeroen Van Renterghem, Chris Vervaet, Thomas De Beer
PURPOSE: The aim of this study was to investigate (i) the influence of drug solid-state (crystalline or dissolved in the polymer matrix) on the melt viscosity and (ii) the influence of the drug concentration, temperature and shear rate on polymer crystallization using rheological tests. METHODS: Poly (ethylene oxide) (PEO) (100.000 g/mol) and physical mixtures (PM) containing 10-20-30-40% (w/w) ketoprofen or 10% (w/w) theophylline in PEO were rheologically characterized...
August 15, 2017: Pharmaceutical Research
https://www.readbyqxmd.com/read/28808925/recommendations-of-the-spanish-brachytherapy-group-geb-of-spanish-society-of-radiation-oncology-seor-and-the-spanish-society-of-medical-physics-sefm-for-high-dose-rate-hdr-non-melanoma-skin-cancer-brachytherapy
#4
S Rodríguez, M Arenas, C Gutierrez, J Richart, J Perez-Calatayud, F Celada, M Santos, A Rovirosa
Clinical indications of brachytherapy in non-melanoma skin cancers, description of applicators and dosimetry recommendations are described based on the literature review, clinical practice and experience of Spanish Group of Brachytherapy and Spanish Society of Medical Physics reported in the XIV Annual Consensus Meeting on Non Melanoma Skin Cancer Brachytherapy held in Benidorm, Alicante (Spain) on October 21st, 2016. All the recommendations for which consensus was achieved are highlighted in blue. Regular and small surfaces may be treated with Leipzig, Valencia, flap applicators or electronic brachytherapy (EBT)...
August 14, 2017: Clinical & Translational Oncology
https://www.readbyqxmd.com/read/28807087/allergic-bronchopulmonary-mycosis-due-to-exposure-to-eurotium-herbariorum-after-the-great-east-japan-earthquake
#5
Chiyako Oshikata, Maiko Watanabe, Akemi Saito, Masatsugu Ishida, Seiichi Kobayashi, Rumi Konuma, Yoichi Kamata, Jun Terajima, Junichi Cho, Masaru Yanai, Naomi Tsurikisawa
BACKGROUND: Indoor mold levels typically increase after natural disasters, flooding, and water damage. Eurotium herbariorum is the sexual stage of Aspergillus glaucus. Case Presentation A 66-year-old, Japanese male, ex-smoker had been diagnosed with bronchial asthma when he was five years old; he achieved remission at the age of 13 years. He was displaced from his home during the Great East Japan Earthquake on March 11, 2011 and moved to temporary housing in Miyagi Prefecture in June 2011...
August 15, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28805706/waveguide-plasmon-resonance-of-arrayed-metallic-nanostructures-patterned-on-a-soft-substrate-by-direct-contact-printing-lithography
#6
Wei-Xiang Su, Chun-Ying Wu, Yung-Chun Lee
This paper presents a direct contact printing method to obtain arrayed metallic nanostructures on a soft polymer substrate. It utilizes a polydimethylsiloxane (PDMS) mold replicated from silicon molds to transfer metallic nanopatterns onto a polymer substrate based on differences in interfacial bonding energy. Arrayed metallic nanodisks with a disk diameter down to 180 nm and a center-to-center pitch around 400 nm are experimentally patterned on a PET substrate. The patterned metallic nanostructures are then spin-coated with a polymer layer; which mechanically secures the patterned nanostructures and optically allows waveguide plasmon resonance being excited by incident EM waves...
August 13, 2017: Sensors
https://www.readbyqxmd.com/read/28802095/the-diagnostic-utility-of-merkel-cell-polyomavirus-immunohistochemistry-in-a-fine-needle-aspirate-of-metastatic-merkel-cell-carcinoma-of-unknown-primary-to-the-pancreas
#7
Long Li, Kyle Molberg, Naga Cheedella, Joel Thibodeaux, Stacy Hinson, Elena Lucas
Merkel cell carcinoma (MCC) is an aggressive skin tumor with a high tendency for metastases. We report a case of MCC initially presenting as axillary and pancreatic metastases. A 33-year-old HIV-positive Hispanic male presented with a history of a rapidly growing axillary mass. A needle core biopsy demonstrated an epithelioid neoplasm composed of small to medium-sized cells with high nuclear-cytoplasmic ratio, nuclear molding, and frequent mitotic figures. A subsequent PET scan revealed a 1.5 cm FDG avid mass in the pancreas...
August 12, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28800664/outcomes-of-cranioplasty-with-preformed-titanium-versus-freehand-molded-polymethylmethacrylate-implants
#8
Julius Höhne, Korbinian Werzmirzowsky, Christian Ott, Christoph Hohenberger, Bahaa Ghareb Hassanin, Alexander Brawanski, Karl-Michael Schebesch
No abstract text is available yet for this article.
August 11, 2017: Journal of Neurological Surgery. Part A, Central European Neurosurgery
https://www.readbyqxmd.com/read/28799153/-fungi-in-the-gut-the-gut-mycobiome
#9
Herbert Hof
Many different fungi, including yeasts and molds, can be found in the intestinal tract of humans constituting the gut mycobiome. In case the bacterial flora is altered, the fungal flora may react inversely. By a so-called fungal diet, however, the composition of the mycobiome can hardly be influenced. Whereas some fungi are only transiently present in the gut after oral uptake, others, such as Candida, Saccharomyces, Rhodotorula, Trichosporon, Geotrichum, amongst others, are members of the residential, autochthonous gut flora...
August 2017: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/28798866/in-vitro-and-in-vivo-degradation-behavior-of-poly-trimethylene-carbonate-co-d-l-lactic-acid-copolymer
#10
Zhengyu Ma, Yi Wu, Jing Wang, Changsheng Liu
We present P(TMC-co-DLLA) copolymer with the molar ratio of TMC: DLLA = 15: 85 was used to systematic study of in vivo and in vitro degradation behaviors. Dense homogeneous copolymer specimens were prepared by compression molding method. The in vitro and in vivo degradation were, respectively, performed at simulative body condition and implanted into rat's subcutaneous condition. Investigations were followed via physicochemical and histological analysis such as SEM, GPC, DSC, FTIR and H&E stain. The results demonstrate that copolymeric material can degrade in phosphate buffer solution (PBS) and in rat's body, and the in vivo degradation rate is faster...
August 2017: Regenerative Biomaterials
https://www.readbyqxmd.com/read/28798850/network-simulation-based-optimization-of-centrifugo-pneumatic-blood-plasma-separation
#11
S Zehnle, M Rombach, R Zengerle, F von Stetten, N Paust
Automated and robust separation of 14 μl of plasma from 40 μl of whole blood at a purity of 99.81% ± 0.11% within 43 s is demonstrated for the hematocrit range of 20%-60% in a centrifugal microfluidic polymer disk. At high rotational frequency, red blood cells (RBCs) within whole blood are concentrated in a radial outer RBC collection chamber. Simultaneously, plasma is concentrated in a radial inner pneumatic chamber, where a defined air volume is enclosed and compressed. Subsequent reduction of the rotational frequency to not lower than 25 Hz enables rapid transfer of supernatant plasma into a plasma collection chamber, with highly suppressed resuspension of red blood cells...
March 2017: Biomicrofluidics
https://www.readbyqxmd.com/read/28798548/newborn-ear-deformities-early-recognition-and-novel-nonoperative-techniques
#12
REVIEW
Kelly Schultz, Diana Guillen, Renata S Maricevich
Congenital auricular anomalies are common sources of aesthetic concern and psychosocial distress for both children and their parents. Only one-third of these anomalies self-correct, leaving a large need for acceptable corrective methods. Otoplasty is often the standard treatment; however, newer nonsurgical methods, including splinting and molding in the neonatal period, have shown favorable results without the complications of surgical intervention and with the advantage of early intervention. These treatment options have not yet been widely adopted in Western countries due to delayed diagnosis of auricular deformities and confusion regarding treatment indications and technique...
August 2017: Seminars in Plastic Surgery
https://www.readbyqxmd.com/read/28798185/whole-genome-sequence-of-starmerella-bacillaris-pas13-a-nonconventional-enological-yeast-with-antifungal-activity
#13
Wilson José Fernandes Lemos Junior, Laura Treu, Vinícius da Silva Duarte, Milena Carlot, Chiara Nadai, Stefano Campanaro, Alessio Giacomini, Viviana Corich
Starmerella bacillaris is a fermentative yeast commonly found in vineyards. Here, we present the draft genome sequence of S. bacillaris PAS13, a nonconventional enological yeast with a potential role as a biocontrol agent. This gene sequence will provide insights into the genetic basis of yeast activity against gray mold disease (Botrytis cinerea).
August 10, 2017: Genome Announcements
https://www.readbyqxmd.com/read/28797875/success-rates-characteristics-and-costs-of-articulating-antibiotic-spacers-for-total-knee-periprosthetic-joint-infection
#14
Scott R Nodzo, Keely K Boyle, Sara Spiro, Allina A Nocon, Andy O Miller, Geoffrey H Westrich
BACKGROUND: The optimal type, characteristics, and success rates of articulating antibiotic spacers used during total knee arthroplasty (TKA) periprosthetic joint infection (PJI) have not been well defined in a single series. We sought to (1) determine the success rate for three unique spacer constructs and (2) evaluate any microbiological, surgical, or patient characteristics that would influence the success rate. METHODS: We retrospectively reviewed patients who underwent a two-stage exchange for a TKA PJI with a prefabricated spacer (PREFAB), home-made mold (MOLD), or autoclaved femoral component (AUTOCL)...
August 8, 2017: Knee
https://www.readbyqxmd.com/read/28797495/emergence-of-the-molds-other-than-aspergillus-in-immunocompromised-patients
#15
REVIEW
Sana Arif, John R Perfect
Immunocompromised patients are at high risk for invasive fungal infections (IFIs); although Aspergillus remains the most common IFI caused by molds, other fungi, such as Mucorales, dematiaceous molds, and Fusarium spp, are being seen with increasing frequency. Presentations can vary, but sinopulmonary and disseminated infections are common. Our understanding of the pathogenesis of these infections is rudimentary. Fungal cultures and histopathology remain the backbone of diagnostics, as no good serologic markers are available...
September 2017: Clinics in Chest Medicine
https://www.readbyqxmd.com/read/28797166/patternable-solvent-processed-thermoplastic-graphite-electrodes
#16
Kevin Klunder, Zach Nilsson, Justin Sambur, Charles S Henry
Since their invention in the 1950's, composite carbon electrodes have been employed in a wide variety of applications, ranging from batteries and fuel cells to chemical sensors because they are easy to make and pattern at millimeter scales. Despite their widespread use, traditional carbon composite electrodes have substandard electrochemistry relative to metallic and glassy carbon electrodes. As a result, there is a critical need for new composite carbon electrodes that are highly electrochemically active, have universal and easy fabrication into complex geometries, are highly conductive, and are low cost...
August 10, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28795317/nonsteroidal-anti-inflammatory-drugs-nsaids-inhibit-the-growth-and-reproduction-of-chaetomium-globosum-and-other-fungi-associated-with-water-damaged-buildings
#17
Kelsey Dalmont, Charles L Biles, Heather Konsure, Sujita Dahal, Tyler Rowsey, Matthew Broge, Shubhra Poudyal, Tara Gurung, Sabina Shrestha, Caleb L Biles, Terry Cluck, Alisha Howard
Indoor mold due to water damage causes serious human respiratory disorders, and the remediation to homes, schools, and businesses is a major expense. Prevention of mold infestation of building materials would reduce health problems and building remediation costs. Nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit yeasts and a limited number of filamentous fungi. The purpose of this research was to determine the possible inhibitory activity of nonsteroidal anti-inflammatory drugs (NSAIDs) on germination, fungal growth, and reproduction of Chaetomium globosum and other important filamentous fungi that occur in water-damaged buildings...
August 9, 2017: Mycopathologia
https://www.readbyqxmd.com/read/28792434/collective-migration-of-lens-epithelial-cell-induced-by-differential-microscale-groove-patterns
#18
Chunga Kwon, Youngjun Kim, Hojeong Jeon
Herein, a micro-patterned cell adhesive surface is prepared for the future design of medical devices. One-dimensional polydimethylsiloxane (PDMS) micro patterns were prepared by a photolithography process. We investigated the effect of microscale topographical patterned surfaces on decreasing the collective cell migration rate. PDMS substrates were prepared through soft lithography using Si molds fabricated by photolithography. Afterwards, we observed the collective cell migration of human lens epithelial cells (B-3) on various groove/ridge patterns and evaluated the migration rate to determine the pattern most effective in slowing down the cell sheet spreading speed...
August 9, 2017: Journal of Functional Biomaterials
https://www.readbyqxmd.com/read/28792423/novel-%C3%AE-tcp-pva-bilayered-hydrogels-with-considerable-physical-and-bio-functional-properties-for-osteochondral-repair
#19
Hang Yao, Junpei Kang, Weichang Li, Jian Liu, Renjian Xie, Yingjun Wang, Sa Liu, Dong An Wang, Li Ren
Cartilage repairing graft had been widely studied and the osteochondral replacement hydrogels were proved to be an excellent method in research and clinical. However, it was difficult to solve three main issues in osteochondral replacement preparation at one time: surface lubrication, overall mechanical support and good simulations of cell regeneration. A novel integrated bilayered hydrogel osteochondral replacement was constructed by blending polyvinyl alcohol (PVA) and β-tricalcium phosphate (β-TCP) in this study...
August 9, 2017: Biomedical Materials
https://www.readbyqxmd.com/read/28792045/rapid-fabrication-of-bio-inspired-nanostructure-with-hydrophobicity-and-antireflectivity-on-polystyrene-surface-replicating-from-cicada-wings
#20
Heng Xie, Han-Xiong Huang, Yu-Jiang Peng
The fine nanostructure on the cicada wing of Cryptotympana atrata fabricius, which exhibits hydrophobicity and antireflectivity, is carefully examined. A promising strategy is proposed for facilely and successively replicating the natural functional nanostructure of the cicada wing onto polystyrene (PS) surfaces. First, a nickel replica with tapered nanopores is fabricated by combining electroless plating and subsequent electroplating with the natural cicada wing as an original template. Then, using microinjection compression molding, with the nickel replica as a template, the tapered nanopores are transcribed onto the PS surface, resulting in orderly and densely arranged nanopillars with a mean diameter of about 156 nm and a mean pitch of about 180 nm...
August 9, 2017: Nanoscale
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