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https://www.readbyqxmd.com/read/29334135/liquid-letters
#1
Shaowei Shi, Xubo Liu, Yanan Li, Xuefei Wu, Dong Wang, Joe Forth, Thomas P Russell
Using the interfacial jamming of cellulose nanocrystal (CNC) surfactants, a new concept, termed all-liquid molding, is introduced to produce all-liquid objects that retain the shape and details of the mold with high fidelity, yet remain all liquid and are responsive to external stimuli. This simple process, where the viscosity of the CNC dispersion can range from that of water to a crosslinked gel, opens tremendous opportunities for encapsulation, delivery systems, and unique microfluidic devices. The process described is generally applicable to any functionalized nanoparticles dispersed in one liquid and polymer ligands having complementary functionality dissolved in a second immiscible liquid...
January 15, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29333350/scale-up-of-a-luminescent-solar-concentrator-based-photomicroreactor-via-numbering-up
#2
Fang Zhao, Dario Cambié, Jeroen Janse, Eric W Wieland, Koen P L Kuijpers, Volker Hessel, Michael G Debije, Timothy Noël
The use of solar energy to power chemical reactions is a long-standing dream of the chemical community. Recently, visible-light-mediated photoredox catalysis has been recognized as the ideal catalytic transformation to convert solar energy into chemical bonds. However, scaling photochemical transformations has been extremely challenging due to Bouguer-Lambert-Beer law. Recently, we have pioneered the development of luminescent solar concentrator photomicroreactors (LSC-PMs), which display an excellent energy efficiency...
January 2, 2018: ACS Sustainable Chemistry & Engineering
https://www.readbyqxmd.com/read/29333207/development-and-feasibility-of-a-robotic-laparoscopic-clipping-tool-for-wound-closure-and-anastomosis
#3
Axel Krieger, Justin Opfermann, Peter C W Kim
This paper reports the design, development, and initial evaluation of a robotic laparoscopic clipping tool for single manipulator wound closure and anastomosis (tubular reconnection). The tool deploys biodegradable clips and clasps with the goal of (i) integrating grasping and suturing into a single device for single hand or manipulator use, (ii) applying the equivalent of interrupted sutures without the need of managing suture thread, and (iii) allowing for full six degrees-of-freedom (DOFs) laparoscopic control when mounted on a robot arm...
March 2018: Journal of Medical Devices
https://www.readbyqxmd.com/read/29332999/an-integrated-electrolysis-electrospray-ionization-antimicrobial-platform-using-engineered-water-nanostructures-ewns-for-food-safety-applications
#4
Nachiket Vaze, Yi Jiang, Lucas Mena, Yipei Zhang, Dhimiter Bello, Stephen S Leonard, Anna M Morris, Mary Eleftheriadou, Georgios Pyrgiotakis, Philip Demokritou
Engineered water nanostructures (EWNS) synthesized utilizing electrospray and ionization of water, have been, recently, shown to be an effective, green, antimicrobial platform for surface and air disinfection, where reactive oxygen species (ROS), generated and encapsulated within the particles during synthesis, were found to be the main inactivation mechanism. Herein, the antimicrobial potency of the EWNS was further enhanced by integrating electrolysis, electrospray and ionization of de-ionized water in the EWNS synthesis process...
March 2018: Food Control
https://www.readbyqxmd.com/read/29327014/design-of-biomimetic-substrates-for-long-term-maintenance-of-alveolar-epithelial-cells
#5
James C H Poon, Zhongfa Liao, Takaya Suzuki, Miranda M Carleton, John P Soleas, J Stewart Aitchison, Golnaz Karoubi, Alison P McGuigan, Thomas K Waddell
There is a need to establish in vitro lung alveolar epithelial culture models to better understand the fundamental biological mechanisms that drive lung diseases. While primary alveolar epithelial cells (AEC) are a useful option to study mature lung biology, they have limited utility in vitro. Cells that survive demonstrate limited proliferative capacity and loss of phenotype over the first 3-5 days in traditional culture conditions. To address this limitation, we generated a novel physiologically relevant cell culture system for enhanced viability and maintenance of phenotype...
January 12, 2018: Biomaterials Science
https://www.readbyqxmd.com/read/29324816/changes-in-respiratory-and-non-respiratory-symptoms-in-occupants-of-a-large-office-building-over-a-period-of-moisture-damage-remediation-attempts
#6
Ju-Hyeong Park, Sook Ja Cho, Sandra K White, Jean M Cox-Ganser
There is limited information on the natural history of building occupants' health in relation to attempts to remediate moisture damage. We examined changes in respiratory and non-respiratory symptoms in 1,175 office building occupants over seven years with multiple remediation attempts. During each of four surveys, we categorized participants using a severity score: 0 = asymptomatic; 1 = mild, symptomatic in the last 12 months, but not frequently in the last 4 weeks; 2 = severe, symptomatic at least once weekly in the last 4 weeks...
2018: PloS One
https://www.readbyqxmd.com/read/29322640/conserved-roles-of-osiris-genes-in-insect-development-polymorphism-and-protection
#7
Chris R Smith, Claire Morandin, Moataz Noureddine, Swati Pant
Much of the variation among insects is derived from the different ways that chitin has been molded to form rigid structures, both internal and external. In this study, we identify a highly conserved expression pattern in an insect-only gene family, the Osiris genes, that is essential for development, but also plays a significant role in phenotypic plasticity and in immunity/toxicity responses. The majority of Osiris genes exist in a highly syntenic cluster, and the cluster itself appears to have arisen very early in the evolution of insects...
January 10, 2018: Journal of Evolutionary Biology
https://www.readbyqxmd.com/read/29320571/inhibitory-effect-and-possible-mechanism-of-a-pseudomonas-strain-qba5-against-gray-mold-on-tomato-leaves-and-fruits-caused-by-botrytis-cinerea
#8
Pan Gao, Jiaxing Qin, Delong Li, Shanyue Zhou
The fungal pathogen Botrytis cinerea causes gray mold disease on various hosts, which results in serious economic losses. Over the past several decades, many kinds of fungicides have been used to successfully control the disease. Meanwhile, the uses of fungicides lead to environmental pollution as well as a potential threat to the human health by the chemical residues in tomato fruit. Also, the gray mold disease is difficult to control with fungicides. Therefore, exploring alternative measures such as biological controls could be the best choice to control the disease and alleviate damages caused by fungicides...
2018: PloS One
https://www.readbyqxmd.com/read/29316687/contact-behavior-of-composite-crtisin-coated-dies-in-compressing-of-mg-alloy-sheets-under-high-pressure
#9
T S Yang, S H Yao, Y Y Chang, J H Deng
Hard coatings have been adopted in cutting and forming applications for nearly two decades. The major purpose of using hard coatings is to reduce the friction coefficient between contact surfaces, to increase strength, toughness and anti-wear performance of working tools and molds, and then to obtain a smooth work surface and an increase in service life of tools and molds. In this report, we deposited a composite CrTiSiN hard coating, and a traditional single-layered TiAlN coating as a reference. Then, the coatings were comparatively studied by a series of tests...
January 8, 2018: Materials
https://www.readbyqxmd.com/read/29314049/detection-and-classification-of-citrus-green-mold-caused-by-penicillium-digitatum-using-multispectral-imaging
#10
Mahmood Reza Golzarian, Narges Ghanei Ghooshkhaneh, Mojtaba Mamarabadi
BACKGROUND: Fungal decay is a prevalent condition that mainly occurs during transportation of products to consumers (from harvest to consumption) and adversely affect post-harvest operations and sales of citrus fruit. There are a variety of methods to control pathogenic fungi including UV-assisted removal of fruit with suspected infection before storage, which is a time-taking task coupled with human health risks. Therefore, it is essential to adopt efficient dependable alternatives for early decay detection...
January 4, 2018: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29313080/evolution-of-potent-odorants-within-the-volatile-metabolome-of-high-quality-hazelnuts-corylus-avellana-l-evaluation-by-comprehensive-two-dimensional-gas-chromatography-coupled-with-mass-spectrometry
#11
Marta Cialiè Rosso, Erica Liberto, Nicola Spigolon, Mauro Fontana, Marco Somenzi, Carlo Bicchi, Chiara Cordero
Within the pattern of volatiles released by food products (volatilome), potent odorants are bio-active compounds that trigger aroma perception by activating a complex array of odor receptors (ORs) in the regio olfactoria. Their informative role is fundamental to select optimal post-harvest and storage conditions and preserve food sensory quality. This study addresses the volatile metabolome from high-quality hazelnuts (Corylus avellana L.) from the Ordu region (Turkey) and Tonda Romana from Italy, and investigates its evolution throughout the production chain (post-harvest, industrial storage, roasting) to find functional correlations between technological strategies and product quality...
January 9, 2018: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/29310879/fracture-analysis-of-cad-cam-high-density-polymers-used-for-interim-implant-supported-fixed-cantilevered-prostheses
#12
Burak Yilmaz, Gülce Alp, Jeremy Seidt, William M Johnston, Roger Vitter, Edwin A McGlumphy
STATEMENT OF PROBLEM: The load-to-fracture performance of computer-assisted design and computer-assisted manufacturing (CAD-CAM) high-density polymer (HDP) materials in cantilevers is unknown. PURPOSE: The purposes of this in vitro study were to evaluate the load-to-fracture performance of CAD-CAM-fabricated HDPs and to compare that with performance of autopolymerized and injection-molded acrylic resins. MATERIAL AND METHODS: Specimens from 8 different brands of CAD-CAM HDPs, including Brylic Solid (BS); Brylic Gradient (BG); AnaxCAD Temp EZ (AE); AnaxCAD Temp Plus (AP); Zirkonzahn Temp Basic (Z); GDS Tempo-CAD (GD); Polident (Po); Merz M-PM-Disc (MAT); an autopolymerized acrylic resin, Imident (Conv) and an injection-molded acrylic resin, SR-IvoBase High Impact (Inj) were evaluated for load-to-fracture analysis (n=5)...
January 5, 2018: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/29310769/indoor-environmental-interventions-for-furry-pet-allergens-pest-allergens-and-mold-looking-to-the-future
#13
Sharon K Ahluwalia, Elizabeth C Matsui
Over the last 2 to 3 decades, significant advances have been made in understanding the role that indoor allergen exposures play with regard to respiratory health. Multiple studies have confirmed that sensitization and exposure to indoor allergens can be a risk factor for asthma morbidity. Environmental interventions targeting key indoor allergens have been evaluated with the aims of examining their causal effects on asthma-related outcomes and identifying clinically efficacious interventions to incorporate into treatment recommendations...
January 2018: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29310223/portable-vibration-assisted-filtration-device-for-on-site-isolation-of-blood-cells-or-pathogenic-bacteria-from-whole-human-blood
#14
Yong Tae Kim, Kyun Joo Park, Seyl Kim, Soon Ae Kim, Seok Jae Lee, Do Hyun Kim, Tae Jae Lee, Kyoung G Lee
Isolation of specific cells from whole blood is important to monitor disease prognosis and diagnosis. In this study, a vibration-assisted filtration (VF) device has been developed for isolation and recovery of specific cells such as leukocytes and pathogenic bacteria from human whole blood. The VF device is composed of three layers which was fabricated using injection molding with cyclic olefin copolymer (COC) pellets consisting of: a top layer with coin-type vibration motor (Ф = 10mm), a middle plate with a 1μm or 3μm-pore filter membrane to separate of Staphylococcus aureus (S...
March 1, 2018: Talanta
https://www.readbyqxmd.com/read/29309079/fundamentals-of-rapid-injection-molding-for-microfluidic-cell-based-assays
#15
Ulri N Lee, Xiaojing Su, David J Guckenberger, Ashley M Dostie, Tianzi Zhang, Erwin Berthier, Ashleigh B Theberge
Microscale cell-based assays have demonstrated unique capabilities in reproducing important cellular behaviors for diagnostics and basic biological research. As these assays move beyond the prototyping stage and into biological and clinical research environments, there is a need to produce microscale culture platforms more rapidly, cost-effectively, and reproducibly. 'Rapid' injection molding is poised to meet this need as it enables some of the benefits of traditional high volume injection molding at a fraction of the cost...
January 8, 2018: Lab on a Chip
https://www.readbyqxmd.com/read/29308592/abuse-deterrent-features-of-an-extended-release-morphine-drug-product-developed-using-a-novel-injection-molding-technology-for-oral-drug-delivery
#16
Nikolaj Skak, Torben Elhauge, Jeffrey M Dayno, Karsten Lindhardt
OBJECTIVE: A novel technology platform (Guardian™ Technology, Egalet Corporation, Wayne, PA) was used to manufacture morphine abuse-deterrent (AD), extended-release (ER), injection-molded tablets (morphine-ADER-IMT; ARYMO® ER [morphine sulfate] ER tablets; Egalet Corporation), a recently approved morphine product with AD labeling. The aim of this article is to highlight how the features of Guardian™ Technology are linked to the ER profile and AD characteristics of morphine-ADER-IMT...
November 2017: Journal of Opioid Management
https://www.readbyqxmd.com/read/29308100/a-reproducible-method-for-%C3%AE-m-precision-alignment-of-pdms-microchannels-with-on-chip-electrodes-using-a-mask-aligner
#17
J Cottet, C Vaillier, F Buret, M Frénéa-Robin, P Renaud
This paper describes a reproducible method for μm precision alignment of polydimethylsiloxane (PDMS) microchannels with coplanar electrodes using a conventional mask aligner for lab-on-a-chip applications. It is based on the use of a silicon mold in combination with a PMMA sarcophagus for precise control of the parallelism between the top and bottom surfaces of molded PDMS. The alignment of the fabricated PDMS slab with electrodes patterned on a glass chip is then performed using a conventional mask aligner with a custom-made steel chuck and magnets...
November 2017: Biomicrofluidics
https://www.readbyqxmd.com/read/29307752/a-2-year-comparative-study-of-mold-and-bacterial-counts-in-air-samples-from-neutral-and-positive-pressure-rooms-in-2-tertiary-care-hospitals
#18
Laura Ryan, Niall O'Mara, Sana Tansey, Tom Slattery, Belinda Hanahoe, Akke Vellinga, Maeve Doyle, Martin Cormican
Immunocompromised patients are at risk of invasive fungal infection. These high-risk patients are nursed in protective isolation to reduce the risk of nosocomial aspergillosis while in hospital-ideally in a positive pressure single room with high-efficiency particulate air filtration. However, neutral pressure rooms are a potential alternative, especially for patients requiring both protective and source isolation. This study examined mold and bacterial concentrations in air samples from positive and neutral pressure rooms to assess whether neutral pressure rooms offer a similar environment to that of positive pressure rooms in terms of mold concentrations in the air...
January 4, 2018: American Journal of Infection Control
https://www.readbyqxmd.com/read/29305659/development-of-micro-mechanical-device-having-two-dimensional-array-of-micro-chambers-for-cell-stretching
#19
K Minami, T Hayashi, K Sato, T Nakahara
This paper presents a novel cell stretching micro device having two-dimensional array of micro chambers. It enables an in situ time-lapse observation of stretched cell by using an optical microscope with high measurement efficiency. The presented device consists of a cell culture dish and the array of micro chambers made of silicone elastomer and extension structures made of photocurable resin, and is fabricated with MEMS technology. The fabrication process of the thin micro chamber array combines photoresist mold and lift-off process based on conventional photolithography...
January 5, 2018: Biomedical Microdevices
https://www.readbyqxmd.com/read/29304484/evaluation-of-resistance-to-botrytis-elliptica-in-lilium-hybrid-cultivars
#20
Xue Gao, Qi Cui, Qin-Zheng Cao, Yu-Qian Zhao, Qiang Liu, Heng-Bin He, Gui-Xia Jia, Dong-Mei Zhang
Gray mold disease, caused by the fungus Botrytis elliptica, is one of the major diseases affecting Lilium species, and it has become a limiting factor in the production of ornamental lilies. To support selecting and breeding Botrytis-resistant cultivars, a total of 50 Lilium cultivars belonging to seven hybrid types were evaluated using a detached leaf technique for resistance to B. elliptica. Through resistance evaluations, Oriental × Trumpet and Oriental hybrid cultivars were classified as resistant lines, while Asiatic and Trumpet hybrids were classified as susceptible lines...
December 15, 2017: Plant Physiology and Biochemistry: PPB
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