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Orthokeratology

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https://www.readbyqxmd.com/read/28316195/-analysis-of-corneal-complications-in-children-wearing-orthokeratology-lenses-at-night
#1
C X Miao, X Y Xu, H Zhang
Objective: To explore the characteristics, prognoses and corneal complications of children wearing orthokeratology lenses (Ortho-K) at night. Methods: Retrospective case analysis. A total of 113 cases (219 eyes) wore Ortho-K for myopia at night, including 7 cases with unilateral glass wear. The average age was (11.5±2.0) years old. The myopia ranged from -1.00 D to -9.00 D in all eyes and from -2.00 D to -4.00 D in 157 of them. Examinations were performed before lens wearing, at 1 hour, the next morning, 2 days, 3 days, 1 week and 2 weeks after lens wearing, and thereafter once a month...
March 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/28291200/-stabilizing-effect-of-orthokeratology-lenses-ten-year-follow-up-results
#2
E P Tarutta, T Yu Verzhanskaya
The global prevalence of myopia in adults varies between 20-50% in Europe and the US and 60-90% in Asian countries. According to WHO, myopia is one of the five leading causes of blindness and low vision in the world. Prevention or deceleration of myopia progression is an important public health problem. In recent years, orthokeratology (ortho-k) contact lenses worn at night have been found effective in slowing down the progression of myopia, however, the follow-up period in related studies is no longer than five years...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28253404/protective-role-of-orthokeratology-in-reducing-risk-of-rapid-axial-elongation-a-reanalysis-of-data-from-the-romio-and-to-see-studies
#3
Pauline Cho, Sin-Wan Cheung
Purpose: To determine the relative risk of rapid progression and number needed to treat (NNT) in younger and older children using combined data from the retardation of myopia in orthokeratology (ROMIO) and toric orthokeratology-slowing eye elongation (TO-SEE) studies. Methods: Data from 136 subjects of two studies, ROMIO and TO-SEE, were retrieved (72 orthokeratology [ortho-k]: 37 ROMIO, 35 TO-SEE; 64 control: 41 ROMIO, 23 TO-SEE) and the myopia control effect on younger (6-8 years) and older (9-12 years) subjects evaluated...
March 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28244933/prospective-cohort-comparison-of-visual-acuity-and-contrast-sensitivity-between-femto-laser-in-situ-keratomileusis-and-orthokeratology-for-low-to-moderate-myopia
#4
Mingxia Tian, Ping Ma, Guoying Mu
PURPOSE: To compare the visual acuity and contrast sensitivity (CS) after femto laser in situ keratomileusis (fLASIK) and orthokeratology (OK) in patients with low-to-moderate myopia. METHODS: A total of 68 patients were enrolled in this prospective cohort study. Of these, 40 eyes from 40 patients with low-to-moderate myopia underwent fLASIK and 28 eyes from 28 patients underwent OK. In addition to uncorrected distance visual acuity and corrected distance visual acuity, photopic and mesopic CS (with CSV-1000E) were tested before treatment and at 1, 3, and 6 months after treatment...
February 27, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28215499/near-binocular-visual-function-in-young-adult-orthokeratology-versus-soft-contact-lens-wearers
#5
Kate Gifford, Paul Gifford, Peter L Hendicott, Katrina L Schmid
PURPOSE: To compare near point binocular vision function of young adult myopes wearing orthokeratology (OK) lenses to matched single vision soft disposable contact lens (SCL) wearers. METHODS: A retrospective clinical record analysis of all OK wearers (18-30 years) presenting over an 18 month period was undertaken. Data was extracted for 17 OK wearers, with 17 SCL wearers matched for age, refractive error and duration of contact lens wear. Binocular vision data included horizontal phoria (phoria), horizontal base-in (BIFR) and base-out fusional reserves (BOFR) and accommodation accuracy (AA)...
February 15, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/28212157/current-approaches-to-myopia-control
#6
Seo Wei Leo
PURPOSE OF REVIEW: Myopia is a global problem, being particularly prevalent in the urban areas of east and southeast Asia. In addition to the direct economic and social burdens, associated ocular complications may lead to substantial vision loss. With prevalence of myopia above 80% and high myopia over 20%, it is crucial to control myopia. The aim of this review to is provide an update on the interventions to slow the onset of myopia and retard its progression. RECENT FINDINGS: The epidemic of myopia is characterized by increasingly early onset, combined with high myopia progression rates...
February 15, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28167204/changes-in-corneal-sub-basal-nerve-morphology-and-sensitivity-during-orthokeratology-recovery-of-change
#7
Edward Lum, Blanka Golebiowski, Helen A Swarbrick
PURPOSE: To investigate the recovery of changes in corneal nerve morphology and sensitivity in orthokeratology (OK) following lens wear discontinuation, over a 3-month period. METHODS: Sixteen myopic subjects who wore OK lenses during sleep for 3 months discontinued lens wear for 3 months. Corneal nerve morphology and sensitivity were assessed 3 h after waking on the right eye only at the pre-lens wear baseline and after lens wear discontinuation. Corneal nerve fiber density (NFD) and global nerve fiber orientation (GNFO) were assessed by sampling a 1 mm(2) area of the sub-basal nerve plexus at the corneal apex and temporal mid-periphery using in vivo confocal microscopy...
February 3, 2017: Ocular Surface
https://www.readbyqxmd.com/read/28166436/interventions-to-reduce-myopia-progression-in-children
#8
Su Ann Tay, Sonal Farzavandi, Donald Tan
Efforts to reduce the progression of myopia in childhood are on the rise, due to an increasing incidence of myopia worldwide and its associated sight-threatening complications. Interventions are aimed at reducing myopia in childhood and include environmental considerations, spectacles, contact lenses, and pharmacological agents. We reviewed recent literature with interventions aimed at reducing myopia progression in children and found that a number of interventions were significant in reducing the progression of myopia...
March 2017: Strabismus
https://www.readbyqxmd.com/read/28114568/conjunctival-microbiome-changes-associated-with-soft-contact-lens-and-orthokeratology-lens-wearing
#9
Haikun Zhang, Fuxin Zhao, Diane S Hutchinson, Wenfeng Sun, Nadim J Ajami, Shujuan Lai, Matthew C Wong, Joseph F Petrosino, Jianhuo Fang, Jun Jiang, Wei Chen, Peter S Reinach, Jia Qu, Changqing Zeng, Dake Zhang, Xiangtian Zhou
Purpose: Usage of different types of contact lenses is associated with increased risk of sight-threatening complications. Changes in the ocular microbiome caused by contact lens wear are suggested to affect infection development in those individuals. To address this question, this study compares conjunctival microbial communities in contact lens wearers with those in noncontact lens wearers. Methods: Paired-end sequencing of the V3 region of the 16S rRNA gene was used to characterize the bacterial communities on the conjunctival surfaces of contact lens wearers and nonwearers...
January 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28092397/update-on-orthokeratology-in-managing-progressive-myopia-in-children-efficacy-mechanisms-and-concerns
#10
Xintong Li, Ilana B Friedman, Norman B Medow, Cheng Zhang
Myopia is an important public health issue, and high myopia may lead to severe complications if left untreated. Orthokeratology lenses, worn overnight to reshape the cornea, are one of many recent modalities used to slow down the progression of myopia in children. This treatment has been proven successful, as evidenced by decreased spherical refractive error and axial length relative to the control at interval follow-up ranging from 6 months to 5 years. In this systematic review, the authors collected published controlled studies that analyzed the efficacy of orthokeratology lens wear and calculated longitudinal relative changes in axial length, revealing a weighted average of -45...
January 13, 2017: Journal of Pediatric Ophthalmology and Strabismus
https://www.readbyqxmd.com/read/28079814/predictive-role-of-corneal-q-value-differences-between-nasal-temporal-and-superior-inferior-quadrants-in-orthokeratology-lens-decentration
#11
Juan Li, Cheng Yang, Wenjuan Xie, Guanrong Zhang, Xue Li, Shujun Wang, Xiaohong Yang, Jin Zeng
BACKGROUND: To investigate the association between pretreatment corneal parameters and orthokeratology lens decentration. METHODS: This retrospective study included a total of 108 eyes in 60 myopia patients, who were divided into a lens-decentration and a control group. Various pretreatment corneal parameters were analyzed by receiver operating characteristic curves (ROC curves), including corneal horizontal and vertical curvatures, diopter, corneal eccentricity (E-value), asphericity (Q-value), diameter, and astigmatism, to establish a reliable predictive model for orthokeratology lens decentration...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28078849/effects-of-carbomer-eye-drops-in-combination-with-orthokeratology-lens-in-treating-adolescent-myopia
#12
LETTER
Y H Shi, L T Zhou, C X Zhang, Y Z Li, J Z Zhang, H M Zhou, Y G Li, T Liu, L L Zhang, L N Sun, Z Chen
To investigate the effects of carbomer eye drops (CED) during long-time wearing of overnight orthokeratology lens of adolescents with myopia, 260 teenagers with myopia treated in the Henan Provincial People’s Hospital from June 2012 to August 2014 and followed-up for more than 2 years were enrolled. All the patients underwent regular fitting of orthokeratology lens. They were divided into a CED (Vidisic) group (130 cases, 260 eyes treated with CED) and rewetting drops (RD) (Baushe and Lomb) group (130 cases, 260 eyes treated with RD)...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28060144/effect-of-overnight-wear-orthokeratology-lenses-on-corneal-shape-and-tears
#13
Jian Li, Ping Dong, Hu Liu
OBJECTIVE: The aim of this study was to explore the effects of the overnight wear orthokeratology (OK) lenses on corneal shape and tear film stability. METHODS: Forty patients with myopia aged between 11 and 18 years who wore OK lens continuously for more than 1 year were selected. Refractive error (D), corneal curvature, corneal surface regularity index (SRI), tear breakup time (TBUT), Schirmer I test score, and corneal staining were measured at the following time points: 1 week before wearing the OK lens (T0) and 1 week (T1), 1 month (T2), 3 months (T3), 6 months (T4), and 12 months (T5) after wear...
January 4, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/28038841/discontinuation-of-orthokeratology-on-eyeball-elongation-doee
#14
P Cho, S W Cheung
PURPOSE: To evaluate and compare changes in axial elongation, over a 14-month period, in subjects who discontinued and then resumed ortho-k lens wear with those who continued to wear their lenses or spectacles following a 2-year myopia control study. METHOD: This single masked, prospective study recruited subjects who had just completed a 2-year myopia control study. Ortho-k subjects were classified as Group OKc, in which subjects continued ortho-k lens wear for the duration of the study; or Group OKd in which subjects discontinued lens wear for seven months and wore single-vision spectacles (Phase I) and then resumed ortho-k lens wear for another seven months (Phase II)...
December 27, 2016: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/27980362/effectiveness-of-toric-orthokeratology-in-the-treatment-of-patients-with-combined-myopia-and-astigmatism
#15
RANDOMIZED CONTROLLED TRIAL
Byul Lyu, Kyu Yeon Hwang, Sun Young Kim, Su Young Kim, Kyung Sun Na
PURPOSE: The purpose of this multi-institute, single-group clinical trial was to evaluate the effectiveness and safety of toric orthokeratology lenses for the treatment of patients with combined myopia and astigmatism. METHODS: A total of 44 patients were included in this clinical trial. The patients ranged in age from 7 to 49 years, with myopia of -0.75 to -6.0 diopters (D) and astigmatism of 1.25 to 4.0 D. After excluding 21 subjects, 23 subjects (39 eyes) were analyzed after toric orthokeratology lens use...
December 2016: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/27898447/a-review-of-the-potential-factors-influencing-myopia-progression-in-children-using-orthokeratology
#16
REVIEW
Xiao Yang, Zhouyue Li, Junwen Zeng
Myopia has become a worldwide public health issue. Recent studies have consistently reported that orthokeratology (Ortho-K) significantly inhibits the progression of myopia by slowing the elongation of axial length. It has been hypothesized that this effect results from the induction of peripheral myopic defocus, which is a result of the effects of the Ortho-K lenses on the midperipheral corneal topography. Previous studies have investigated the relationship between predicting factors and the inhibitory effect of Ortho-K for slowing childhood myopic progression and found some meaningful results; however, some of the findings are controversial...
November 2016: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/27898441/epidemiology-of-myopia
#17
REVIEW
Pei-Chang Wu, Hsiu-Mei Huang, Hun-Ju Yu, Po-Chiung Fang, Chueh-Tan Chen
Myopia is not a simple refractive error, but an eyesight-threatening disease. There is a high prevalence of myopia, 80% to 90%, in young adults in East Asia; myopia has become the leading cause of blindness in this area. As the myopic population increases globally, the severity of its impact is predicted. Approximately one fifth of the myopic population has high myopia (≥-6 diopters), which results in irreversible vision loss such as retinal detachment, choroidal neovascularization, cataracts, glaucoma, and macular atrophy...
November 2016: Asia-Pacific Journal of Ophthalmology
https://www.readbyqxmd.com/read/27873014/binocular-function-changes-produced-in-response-to-overnight-orthokeratology
#18
Gema Felipe-Marquez, María Nombela-Palomo, Catalina Palomo-Álvarez, Isabel Cacho, Amelia Nieto-Bona
PURPOSE: To analyze the binocular function changes produced on subjects undergoing overnight orthokeratology (OK) treatment over short-term (3 months) and long-term (3 years) wear. METHODS: A prospective, longitudinal study on young adult subjects with low to moderate myopia was carried out. Binocular function was assessed by the following sequence of tests: Distance and near horizontal phoria (Von Graefe technique), distance and near horizontal vergence ranges (Risley rotary prisms), accommodative convergence/accommodation (AC/A) ratio (gradient method) and the near point of convergence (standard push-up technique)...
January 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/27867660/corneal-aberrations-contrast-sensitivity-and-light-distortion-in-orthokeratology-patients-1-year-results
#19
Elena Santolaria-Sanz, Alejandro Cerviño, José M González-Méijome
Purpose. To evaluate the corneal higher-order aberrations (HOA), contrast sensitivity function (CSF), and light distortion (LD) in patients undergoing orthokeratology (OK). Methods. Twenty healthy subjects (mean age: 21.40 ± 8 years) with mean spherical equivalent refractive error M = -2.19 ± 0.97 D were evaluated at 1 day, 1 month, and 1 year after starting OK treatment. Monocular LD, photopic monocular CSF, and corneal HOA for 6 mm pupil size were measured. Results. LD showed an increase after the first night (p < 0...
2016: Journal of Ophthalmology
https://www.readbyqxmd.com/read/27861262/tear-film-osmolarity-in-response-to-long-term-orthokeratology-treatment
#20
Amelia Nieto-Bona, María Nombela-Palomo, Gema Felipe-Márquez, Miguel A Teus
PURPOSE: To compare tear film osmolarity (TFO) measurements in non-contact lens (CL) wearers and wearers of hydrogel or overnight orthokeratology (OK) CLs, and to assess possible effects of long-term OK on TFO. METHODS: Overall, 108 subjects with moderate myopia participated in 2 experiments, and TFO was measured using the TearLab osmolarity system. In experiment 1, TFO measurements were made in 77 right eyes of 23 non-CL wearers, 26 hydrogel wearers, and 28 OK wearers...
November 16, 2016: Eye & Contact Lens
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