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Eve C Feinberg
"The hardest thing to explain is the glaringly evident which everybody has decided not to see." - Ayn Rand, The Fountainhead.
March 8, 2018: Fertility and Sterility
Tiago B Ferreira, João Pinheiro, Leyre Zabala, Filomena J Ribeiro
PURPOSE: To compare the clinical outcomes after cataract surgery with implantation of a monofocal or an extended-range-of-vision intraocular lens (IOL). SETTING: Hospital da Luz, Lisbon Portugal. DESIGN: Prospective case series. METHODS: Patients who previously had myopic laser in situ keratomileusis (LASIK) had cataract surgery with bilateral implantation of an extended-range-of-vision IOL (Tecnis Symfony) or a monofocal IOL (Tecnis ZCB00)...
March 8, 2018: Journal of Cataract and Refractive Surgery
Enrique Barragán-Garza, Douglas D Koch, Luis G Vargas, Alan Lang, Adam Roy
PURPOSE: To assess the clinically acceptable range of inlay decentration with respect to the light-constricted pupil center and the coaxially sighted corneal light reflex (CSCLR) for an inlay (Raindrop Near Vision Inlay; ReVision Optics, Inc., Lake Forest, CA) that reshapes the anterior corneal surface. METHODS: In this retrospective, observational cohort study of 115 patients with emmetropic or low hyperopic presbyopia who were implanted with a shape-changing corneal inlay, visual acuity, task performance (in good and dim light), reports of halos and glare, and satisfaction data were collected from the preoperative and 3-month postoperative examinations...
March 1, 2018: Journal of Refractive Surgery
Yu Zhang, Yue-Guo Chen
BACKGROUND: To compare the incidence of rainbow glare (RG) after femtosecond laser assisted-LASIK (FS-LASIK) using the upgraded FS200 femtosecond laser with different flap cut parameter settings. METHODS: A consecutive series of 129 patients (255 eyes) who underwent FS-LASIK for correcting myopia and/or astigmatism using upgraded WaveLight FS200 femtosecond laser with the original settings was included in group A. Another consecutive series of 129 patients (255 eyes) who underwent FS-LASIK using upgraded WaveLight FS200 femtosecond laser with flap cut parameter settings changed (decreased pulse energy, spot and line separation) was included in group B...
March 5, 2018: BMC Ophthalmology
Ping-Pin Zheng, Johan M Kros, Jin Li
Two autologous chimeric antigen receptor (CAR) T cell therapies (Kymriah™ and Yescarta™) were recently approved by the FDA. Kymriah™ for the treatment of pediatric patients and young adults with refractory or relapse (R/R) B cell precursor acute lymphoblastic leukemia and Yescarta™ for the treatment of adult patients with R/R large B cell lymphoma. In common, both drugs are CD19-specific CAR T cell therapies lysing CD19-positive targets. Their dramatic efficacy in the short term has been highlighted by many media reports...
March 1, 2018: Drug Discovery Today
Malgorzata Zalesinska
A proper visual performance by drivers can be ensured by, among else, a correct distribution of luminance in their field of view. At night, when the driver's sight is adapted to low luminance levels, high luminance level objects located near the road may be a source of glare, which is not only a nuisance, but it may also blind the driver. For many years, LED billboards (light-emitting diode billboards) have been installed near roads. Such billboards are usually large, have high luminance and show dynamically changing images...
February 28, 2018: Accident; Analysis and Prevention
Gitansha Shreyas Sachdev, Shreyas Ramamurthy, Umesh Sharma, Ramamurthy Dandapani
Purpose: The aim of this study was to analyze the objective and subjective visual outcomes of patients bilaterally implanted with the extended range of vision intraocular lens (EROV IOL), the Tecnis Symfony. Methods: This was a prospective interventional case series conducted at a tertiary eye care hospital in South India. The study included patients with bilateral implantation of EROV IOLs. The uncorrected and corrected visual acuity for distance, intermediate, and near vision was recorded at 6 weeks and 6 months' postoperative visit...
March 2018: Indian Journal of Ophthalmology
Ilona Fridman, Paul A Glare, Stacy Stabler, Andrew S Epstein, Alison Wiesenthal, Thomas W Leblanc, E Tory Higgins
BACKGROUND: Negative attitudes toward hospice care might prevent patients with cancer from discussing and choosing hospice as they approach end of life. When making a decision, people often naturally focus on either expected benefits or avoidance of harm. Behavioral research demonstrated that framing information in an incongruent manner with patients' underlying motivational focus reduces their negative attitudes toward a disliked option. OBJECTIVE: Our study tests this communication technique with cancer patients, aiming to reduce negative attitudes toward a potentially beneficial but often-disliked option: hospice care...
February 20, 2018: Journal of Pain and Symptom Management
Roberto García-Roa, Jorge Sáiz, Belén Gómara, Pilar López, José Martín
Knowledge about chemical communication in some vertebrates is still relatively limited. Squamates are a glaring example of this, even when recent evidences indicate that scents are involved in social and sexual interactions. In lizards, where our understanding of chemical communication has considerably progressed in the last few years, many questions about chemical interactions remain unanswered. A potential reason for this is the inherent complexity and technical limitations that some methodologies embody when analyzing the compounds used to convey information...
February 2018: Ecology and Evolution
Ding Han, Jana Wegrzyn, Hua Bi, Ruihua Wei, Bin Zhang, Xiaorong Li
AIMS: Pattern-related visual stress (PRVS) refers to the perceptual difficulties experienced by some individuals when exposed to high contrast striped patterns. People with PRVS were reported to have reduced sensitivity to global motion at baseline testing and the difference disappears at a second estimate. The present study was to investigate the effect of practice on global motion threshold in adults with and without PRVS. METHODS: A total of 101 subjects were recruited and the Wilkins & Evans Pattern Glare Test was used to determine if a subject had PRVS...
2018: PloS One
Samuel Arba Mosquera, Diego de Ortueta, Shwetabh Verma
Background: In this retrospective randomized case series, we compared bilateral symmetry between OD and OS eyes, intercorneal differences and Functional Optical Zone (FOZ) of the corneal aberrations. Methods: Sixty-seven normal subjects (with no ocular pathology) who never had any ocular surgery were bilaterally evaluated at Augenzentrum Recklinghausen (Germany). In all cases, standard examinations and corneal wavefront topography (OPTIKON Scout) were performed...
2018: Eye and Vision (London, England)
Iben B Damgaard, Marcus Ang, Mohamed Farook, Hla M Htoon, Jodhbir S Mehta
PURPOSE: To compare intraoperative and postoperative subjective patient experience after small incision lenticule extraction (SMILE) and femtosecond laser-assisted LASIK. METHODS: In a prospective, randomized, paired-eye, single-masked clinical trial at Singapore National Eye Centre, 70 patients were randomly treated with SMILE and LASIK in each eye. The intraoperative questionnaire was completed immediately after surgery and included light perception and levels of anxiety, fear, and discomfort...
February 1, 2018: Journal of Refractive Surgery
Christopher T Lam, Jenna Mueller, Betsy Asma, Mercy Asiedu, Marlee S Krieger, Rhea Chitalia, Denali Dahl, Peyton Taylor, John W Schmitt, Nimmi Ramanujam
INTRODUCTION: We have previously developed a portable Pocket Colposcope for cervical cancer screening in resource-limited settings. In this manuscript we report two different strategies (cross-polarization and an integrated reflector) to improve image contrast levels achieved with the Pocket Colposcope and evaluate the merits of each strategy compared to a standard-of-care digital colposcope. The desired outcomes included reduced specular reflection (glare), increased illumination beam pattern uniformity, and reduced electrical power budget...
2018: PloS One
Adam Reeves, Rebecca Grayhem, Alex D Hwang
Apart from the well-known loss of color vision and of foveal acuity that characterizes human rod-mediated vision, it has also been thought that night vision is very slow (taking up to 40 min) to adapt to changes in light levels. Even cone-mediated, daylight, vision has been thought to take 2 min to recover from light adaptation. Here, we show that most, though not all adaptation is rapid, taking less than 0.6 s. Thus, monochrome (black-white-gray) images can be presented at mesopic light levels and be visible within a few 10th of a second, even if the overall light level, or level of glare (as with passing headlamps while driving), changes abruptly...
2018: Frontiers in Psychology
Katrin Wacker, Jay W McLaren, Katrina M Kane, Sanjay V Patel
PURPOSE: Patients with Fuchs endothelial corneal dystrophy (FECD) often notice poor vision in the morning that improves as the day progresses. In this study, we determined changes in corneal optical properties associated with induced corneal edema. METHODS: Twenty-three phakic eyes (23 participants) with FECD (grades 1-6, modified Krachmer scale) and 8 normal eyes (8 participants) were examined by Scheimpflug photography. Central corneal thickness, high-order aberrations from anterior and posterior corneal surfaces, and backscatter from the anterior, mid-, and posterior cornea were determined from the Scheimpflug images...
March 2018: Cornea
Lu Qieni, Yu Xiaoxue, Ge Baozhen, Chen Tingting
Interferometric particle imaging (IPI) is a robust and popular technique for measuring particle size and velocity. A method based on a template matching algorithm and an auto-correlation method is proposed to simultaneously extract the location and the separation of doublet images of a particle from an IPI focused image. The position coordinate (x,y) of the particle can be determined with high accuracy, as evaluated by using a serial particle mask. Furthermore, the method can be employed to achieve sub-pixel spacing extraction when combined with Gaussian interpolation...
January 22, 2018: Optics Express
Matthew J Hobbs, Matthew P Grainger, Chengxi Zhu, Chee Hing Tan, Jonathan R Willmott
Accurate quantitative temperature measurements are difficult to achieve using focal-plane array sensors. This is due to reflections inside the instrument and the difficulty of calibrating a matrix of pixels as identical radiation thermometers. Size-of-source effect (SSE), which is the dependence of an infrared temperature measurement on the area surrounding the target area, is a major contributor to this problem and cannot be reduced using glare stops. Measurements are affected by power received from outside the field-of-view (FOV), leading to increased measurement uncertainty...
February 5, 2018: Optics Express
Hassan Hashemi, Amin Nabavi, Reza Bayat, Masoumeh Mohebbi
PURPOSE: To evaluate the outcome of additional KeraRing (Mediphacos, Belo Horizonte, Brazil) implantation in patients with keratoconus with previously implanted INTACS (Addition Technology Inc, Fremont, CA) segments. METHODS: The KeraRing was implanted in 5 eyes of 3 patients with keratoconus without removal of previous intrastromal corneal ring segments. Tunnels were created manually. Snellen uncorrected distance visual acuity (UDVA), corrected distance visual acuity, refractive and keratometric values, and higher-order aberrations were recorded before and after KeraRing implantation...
January 30, 2018: Cornea
Matthias Lang
No abstract text is available yet for this article.
January 8, 2018: Deutsches Ärzteblatt International
Asif Khaliq, Sayeeda Amber Sayed, Syed Abdullah Hussaini, Kiran Azam, Mehak Qamar
BACKGROUND: Immunization is the safest and effective measure for preventing and eradicating various communicable diseases. A glaring immunization gap exists between developing and industrialized countries towards immunization, because the developing countries including Pakistan are still striving to provide basic immunization to their children. The purpose of this study was to access the prevalence and factors of missing immunization among under 5-year children of Karachi.. METHODS: A cross sectional study was conducted from June 2015 to October 2015 among different outpatient clinics of Karachi...
October 2017: Journal of Ayub Medical College, Abbottabad: JAMC
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