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https://www.readbyqxmd.com/read/29154919/patient-reported-outcomes-and-opioid-use-by-outpatient-cancer-patients
#1
N Moryl, V Dave, P Glare, A Bokhari, V T Malhotra, A Gulati, J Hung, V Puttanniah, Y Griffo, R Tickoo, A Wiesenthal, S D Horn, C E Inturrisi
The Memorial Sloan-Kettering Pain Registry contains patient characteristics, treatments, and outcomes for a prospective cohort of 1534 chronic pain cancer patients who were seen at outpatient pain service clinics. Average pain intensity (Brief Pain Inventory) was reported as mild by 24.6% of patients, moderate by 41.5%, and severe by 33.9%. The patient's report of average percent pain relief and health state (EQ-5D) was inversely related to average pain intensity category, while measures of pain interference, number of worst pain locations, and physical and psychological distress were directly related to pain intensity category...
November 14, 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29148548/acrylate-based-materials-for-heart-valve-scaffold-engineering
#2
Rosaria Santoro, Seshasailam Venkateswaran, Francesco Amadeo, Rong Zhang, Maura Brioschi, Anthony Callanan, Marco Agrifoglio, Cristina Banfi, Mark Bradley, Maurizio Pesce
Calcific aortic valve disease (CAVD) is the most frequent cardiac valve pathology. Its standard treatment consists of surgical replacement either with mechanical (metal made) or biological (animal tissue made) valve prostheses, both of which have glaring deficiencies. In the search for novel materials to manufacture artificial valve tissue, we have conducted a high-throughput screening with subsequent up-scaling to identify non-degradable polymer substrates that promote valve interstitial cells (VICs) adherence/growth and, at the same time, prevent their evolution toward a pro-calcific phenotype...
November 17, 2017: Biomaterials Science
https://www.readbyqxmd.com/read/29141385/-clinical-observation-of-visual-quality-after-the-individual-implantation-of-intraocular-lens-guided-by-corneal-q-value
#3
F F Cai, G Y Zheng, H J Wang, L Li, Y Liu
Objective: To describe the feasibility of individual IOL implantation guided by corneal Q value and observe patients postoperative visual quality under different residual spherical aberration. Methods: Prospective study. One hundred and twenty cases (171 eyes)cataract patients in our hospital were selected for the individual implantation of intraocular lens guided by corneal Q value which obtained by Oberscan before operation. Based on spherical aberration calculated by corneal Q value, choose appropriate IOL personalitily to make postoperative whole eye surface aberration +0...
November 11, 2017: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29138533/comparison-of-visual-outcomes-after-bilateral-implantation-of-a-diffractive-trifocal-intraocular-lens-and-blended-implantation-of-an-extended-depth-of-focus-intraocular-lens-with-a-diffractive-bifocal-intraocular-lens
#4
André Lins de Medeiros, André Gustavo de Araújo Rolim, Antonio Francisco Pimenta Motta, Bruna Vieira Ventura, César Vilar, Mário Augusto Pereira Dias Chaves, Pedro Carlos Carricondo, Wilson Takashi Hida
Purpose: The purpose of this study was to compare the visual outcomes and subjective visual quality between bilateral implantation of a diffractive trifocal intraocular lens, Alcon Acrysof IQ(®) PanOptix(®) TNFT00 (group A), and blended implantation of an extended depth of focus lens, J&J Tecnis Symfony(®) ZXR00 with a diffractive bifocal intraocular lens, J&J Vision Tecnis(®) ZMB00 (group B). Methods: This prospective, nonrandomized, consecutive, comparative study included the assessment of 40 eyes in 20 patients implanted with multifocal intraocular lens...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29137026/implantation-of-artificialiris-a-customflex-irisprosthesis-in-a-trauma-patient-with-an-artisan-lens-a-case-report-and-review
#5
Farideh Doroodgar, Mahmoud Jabbarvand, Feizollah Niazi, Sana Niazi, Azad Sanginabadi
PURPOSE: To evaluate probable complications of ArtificialIris implantation with iris fixated intraocular lens. METHOD: Development of photophobia, glare, and psychological strain during face-to-face communication in a 23-year-old man with a widespread traumatic iris defect terminate to make a decision for performing implantation of an ArtificialIris (Humanoptics, Erlangen, Germany) under the remnant iris without removing the patient's existing Artisan lens. RESULTS: Without any intraoperative or postoperative complications, the patient's visual acuity increased by 1 line, the endothelial cell loss was comparable with the cell loss associated with standard cataract surgery, and the anterior-chamber depth and anterior-chamber anatomy did not change...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29120714/functional-magnetic-resonance-imaging-to-assess-neuroadaptation-to-multifocal-intraocular-lenses
#6
Andreia M Rosa, Ângela C Miranda, Miguel M Patrício, Colm McAlinden, Fátima L Silva, Miguel Castelo-Branco, Joaquim N Murta
PURPOSE: To evaluate the use of functional magnetic resonance imaging (MRI) to assess neuroadaptation to multifocal intraocular lenses (IOLs). SETTING: Faculty of Medicine, University of Coimbra, Coimbra, Portugal. DESIGN: Prospective case study. METHODS: Patients with bilateral diffractive IOL implantation after cataract surgery had functional MRI at postoperative intervals of 3 weeks and 6 months. A nonintervention control group was included as proof of concept...
October 2017: Journal of Cataract and Refractive Surgery
https://www.readbyqxmd.com/read/29118500/iridoplasty-of-fixed-dilated-pupil-urrets-zavalia-syndrome-after-deep-anterior-lamellar-keratoplasty
#7
Efthalia Ntora, Nikolaos Ziakas
A 38-year-old woman with advanced keratoconus initially developed Urrets-Zavalia Syndrome (UZS) in the left eye after deep anterior lamellar keratoplasty. During the uneventful surgery, a 7-mm-wide pupil unresponsive to light was noticed. On the first postoperative day, intraocular pressure (IOP) was elevated up to 45 mmHg with shallow anterior chamber (AC). A peripheral iridotomy in 2 o'clock position was conducted and a fixed combination of brinzolamide 1% and timolol 0.5% was administered topically. In the subsequent postoperative period, IOP was successfully reduced, but the patient reported severe photophobia, glare, and decreased vision...
September 2017: Oman Journal of Ophthalmology
https://www.readbyqxmd.com/read/29096997/comparison-of-new-visual-disturbances-after-superior-versus-nasal-temporal-laser-peripheral-iridotomy-a-prospective-randomized-trial
#8
Kavitha Srinivasan, Nazlee Zebardast, Palaniswamy Krishnamurthy, Mohideen Abdul Kader, Ganesh V Raman, Sharmila Rajendrababu, Rengaraj Venkatesh, Pradeep Y Ramulu
PURPOSE: To determine whether laser peripheral iridotomy (LPI) location affects postoperative dysphotopsia symptoms. DESIGN: Multicenter, randomized, prospective, single-masked trial. PARTICIPANTS: Five hundred fifty-nine South Indian patients 30 years of age or older diagnosed as primary angle-closure suspects (PACSs) or with primary angle closure (PAC) or primary angle-closure glaucoma (PACG) in both eyes. METHODS: Patients were randomized to either bilateral superior or bilateral nasal/temporal LPI...
October 30, 2017: Ophthalmology
https://www.readbyqxmd.com/read/29093961/kenya-s-mental-health-law
#9
David M Ndetei, Job Muthike, Erick S Nandoya
Kenya's Mental Health Act 1989 is now outdated. It is a signatory to international rights conventions that provide for state protection of the rights of people with mental illness, their property and their treatment. There is, however, a glaring failure to implement the existing legal provisions. A new Mental Health Bill that aims to respond comprehensively to the challenges affecting mental health services in Kenya is awaiting enactment.
November 2017: BJPsych Int
https://www.readbyqxmd.com/read/29076561/the-effect-of-transient-glare-on-shape-discrimination-threshold-in-myopic-adults
#10
Binbin Su, Bin Zhang, Junping Huang, Wen Xie, Zhenyu Wu, Meng Lin, Zheyi Chen, Haoran Wu, Jun Jiang, Fan Lu
BACKGROUND: The aim was to evaluate the effect of transient glare on shape discrimination threshold (SDT) in myopic adults. METHODS: A total of 162 myopic subjects were enrolled. Of these, 121 had low to mid myopia (-1.00 D to -6.00 D) and 41 had high myopia (-6.13 D to -10.25 D). All subjects had corrected visual acuity of 6/6 or better, and only data for the right eye were included in the study. SDTs were measured with circular D4 (fourth derivative of Gaussian) radial frequency patterns with a radial frequency of four, peak spatial frequency of three cpds, and mean radius of 1...
October 27, 2017: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
https://www.readbyqxmd.com/read/29071154/a-naked-eye-comparison-of-image-quality-between-a-portable-versus-a-fixed-camera-system-for-digital-flexible-ureterorenoscopy-a-single-centre-experience
#11
Mohamed El Howairis, Noor Buchholz
OBJECTIVE: To assess the image quality using the portable OTV-SI (Olympus, Southend, UK) light source system compared to a dedicated fixed standard stack system for flexible ureterorenoscopy (URS) as judged by the human eye. METHODS: We compared two differing flexible URS set-ups. The first was our normal completely digital fixed set-up, comprising a flexible ureteroscope and matching digital stack system (CLV-S40 PRO-6E, Olympus). The second set-up comprised the same digital ureteroscope but with a conventional non-digital stack system and the OTV-SI portable light source...
September 2017: Arab Journal of Urology
https://www.readbyqxmd.com/read/29065016/commentary-racism-and-bias-in-health-professions-education-how-educators-faculty-developers-and-researchers-can-make-a-difference
#12
Reena Karani, Lara Varpio, Win May, Tanya Horsley, John Chenault, Karen Hughes Miller, Bridget O'Brien
The Research in Medical Education (RIME) Program Planning Committee is committed to advancing scholarship in and promoting dialogue about the critical issues of racism and bias in health professions education (HPE). From the call for studies focused on underrepresented learners and faculty in medicine to the invited 2016 RIME plenary address by Dr. Camara Jones, the committee strongly believes that dismantling racism is critical to the future of HPE.The evidence is glaring: Dramatic racial and ethnic health disparities persist in the United States, people of color remain deeply underrepresented in medical school and academic health systems as faculty, learner experiences across the medical education continuum are fraught with bias, and current approaches to teaching perpetuate stereotypes and insufficiently challenge structural inequities...
November 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/29053808/the-impact-of-supplemental-antioxidants-on-visual-function-in-nonadvanced-age-related-macular-degeneration-a-head-to-head-randomized-clinical-trial
#13
RANDOMIZED CONTROLLED TRIAL
Kwadwo Owusu Akuffo, Stephen Beatty, Tunde Peto, Jim Stack, Jim Stringham, David Kelly, Irene Leung, Laura Corcoran, John M Nolan
Purpose: The purpose of this study was to evaluate the impact of supplemental macular carotenoids (including versus not including meso-zeaxanthin) in combination with coantioxidants on visual function in patients with nonadvanced age-related macular degeneration. Methods: In this study, 121 participants were randomly assigned to group 1 (Age-Related Eye Disease Study 2 formulation with a low dose [25 mg] of zinc and an addition of 10 mg meso-zeaxanthin; n = 60) or group 2 (Age-Related Eye Disease Study 2 formulation with a low dose [25 mg] of zinc; n = 61)...
October 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/29044974/quality-of-life-related-variables-measured-for-three-multifocal-diffractive-intraocular-lenses-a-prospective-randomised-clinical-trial
#14
Jorge L Alió, Hakan Kaymak, Detlef Breyer, Beatrice Cochener, Ana B Plaza-Puche
IMPORTANCE: Quality of vision after multifocal intraocular lens (IOLs) implantation in relation to patient satisfaction. It is important to include the evaluation of visual quality and patient satisfaction in clinical practice. BACKGROUND: To evaluate and compare quality of life and patient satisfaction after implantation of three types of diffractive- refractive and apodized-diffractive bifocal and trifocal multifocal IOLs. DESIGN: Comparative, prospective, case series, randomized PARTICIPANTS: 104 eyes of 52 patients METHODS: 104 eyes of 52 patients underwent phacoemulsification surgery with bilateral implantation of one of three multifocal IOLs: AT LISA 809M (Carl Zeiss Meditec) (AT LISA group, 38 eyes), AT LISAtri 839MP (Carl Zeiss Meditec) (AT LISAtri group, 32 eyes), and ReSTOR SN6AD1 (Alcon) (ReSTOR group, 34 eyes)...
October 16, 2017: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/29041099/nanostructured-antireflective-in-plane-solar-harvester
#15
Jared Tippens, Abhijeet Bagal, Xu A Zhang, Chih-Hao Chang
In this work, we demonstrate a two-dimensional nano-hole array that can reduce reflection losses while passively trapping and harvesting incident light. The surface structure is designed to scavenge a small portion of incident light that would typically be lost due to Fresnel reflection, while the majority of light transmits unobstructed like a regular window. The trapping mechanism is dependent on angle and wavelength, and can be designed to selectively trap narrow wavelength bands using the constructed theoretical models...
August 7, 2017: Optics Express
https://www.readbyqxmd.com/read/29036572/dose-effect-of-the-33s-n-%C3%AE-30si-reaction-in-bnct-using-the-new-n_tof-cern-data
#16
M Sabaté-Gilarte, J Praena, I Porras, J M Quesada
33S is a stable isotope of sulphur which is being studied as a potential cooperative target for Boron Neutron Capture Therapy (BNCT) in accelerator-based neutron sources because of its large (n,α) cross section in the epithermal neutron energy range. Previous measurements resolved the resonances with a discrepant description of the lowest-lying and strongest one (at 13.5 keV). However, the evaluations of the major databases do not include resonances, except EAF-2010 which shows smaller values in this range than the experimental data...
September 23, 2017: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/29018762/visual-performance-after-excimer-laser-photorefractive-keratectomy-for-high-myopia
#17
Yu-Ling Liu, Chien-Chi Tseng, Chang-Ping Lin
PURPOSE: To evaluate the efficacy, safety, predictability, and visual performance of excimer laser photorefractive keratectomy (PRK) for myopia greater than -8 diopters (D). METHODS: Fifty-four patients (104 eyes) with myopia from -8D to -13D and cylinder up to -4D received surface ablation technique with the Allegretto wave version 1009-1 excimer laser to correct their refractive error. The patients were examined on days 1, 3, 7, and 14 and 1, 3, 6, and 12 months postoperatively...
April 2017: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/29018756/descemet-s-stripping-automated-endothelial-keratoplasty-for-symptomatic-thioridazine-deposits-in-the-cornea
#18
Masoumeh Mohebbi, Hassan Hashemi, Alireza Mahmoudi, Pasha Anvari
The aim of this study was to use Descemet's Stripping-automated Endothelial Keratoplasty (DSAEK) as a novel treatment to remove thioridazine corneal deposits. A 53-year-old female presented with a 3-month history of visual loss and glare. She had been taking thioridazine (100 mg/day for 1 year) for a psychiatric disorder. Dense yellowish-brown deposits had developed in the posterior stroma. Thioridazine was discontinued, and she was switched to fluoxetine. One year after discontinuation of thioridazine, her symptoms and signs did not resolve...
January 2017: Taiwan Journal of Ophthalmology
https://www.readbyqxmd.com/read/29017826/disability-glare-in-soft-multifocal-contact-lenses
#19
Siegfried Wahl, Luise Fornoff, G Alex Ochakovski, Arne Ohlendorf
PURPOSE: The study investigated the effect of the design of multifocal contact lenses on the sensitivity to contrast and disability glare. METHODS: Contrast sensitivity was measured in 16 young adults (mean age: 25.5±2.5years) at a distance of 2m under two conditions: no-glare and glare. Two designs (Center Near and Center Distance) of the Biofinity soft contact lens were used to simulate correction for presbyopes, while a correction with single vision trial lenses and contact lenses acted as controls...
October 7, 2017: Contact Lens & Anterior Eye: the Journal of the British Contact Lens Association
https://www.readbyqxmd.com/read/29016931/the-tri-institutional-pain-registry-analysis-of-outpatient-pain-management-at-a-specialized-cancer-center
#20
V T Malhotra, P Glare, K S Tan, J Wills, A Gulati, V Puttanniah, J Hung, K Cubert, C Inturrisi
Objectives: The Outpatient Pain Clinics at Memorial Sloan Kettering Cancer Center participated in developing a pain registry to gain insight on the referral and management of cancer pain as related to demographic information, cancer history, prescription records, and interventional pain procedures stored in the institutional database. Methods: Five cohorts (subsets of one another) were defined and compared to describe demographics and differences in management and outcomes by age, race, sex, and cancer type...
June 20, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
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