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https://www.readbyqxmd.com/read/28065179/maternal-fish-oil-supplementation-during-lactation-is-associated-with-reduced-height-at-13-years-of-age-and-higher-blood-pressure-in-boys-only
#1
L Lauritzen, S E Eriksen, M F Hjorth, M S Nielsen, S F Olsen, K D Stark, K F Michaelsen, C T Damsgaard
Dietary long-chain n-3 PUFA (n-3 LCPUFA) in infancy may have long-term effects on lifestyle disease risk. The present follow-up study investigated whether maternal fish oil (FO) supplementation during lactation affected growth and blood pressure in adolescents and whether the effects differed between boys and girls. Mother-infant pairs (n 103) completed a randomised controlled trial with FO (1·5 g/d n-3 LCPUFA) or olive oil (OO) supplements during the first 4 months of lactation; forty-seven mother-infant pairs with high fish intake were followed-up for 4 months as the reference group...
January 9, 2017: British Journal of Nutrition
https://www.readbyqxmd.com/read/28056656/age-and-pubertal-status-related-changes-in-reports-of-perception-of-personal-odors
#2
Lenka Martinec Nováková, Dagmar Plotěná, Jan Havlíček
As previously suggested, preferences for kin body odor might undergo an adaptive change over the course of puberty in order to avoid potential inbreeding, resulting in aversion to body odor of the opposite-gender kin as individuals mature sexually. However, studies based on mutual body odor aversion are rather inconclusive. We therefore investigated whether children's reports of individuals smelling good or bad differed as a function of age and pubertal status. We asked 219 children (94 male) aged 10 to 15 years to assess their pubertal development using a standardized measure and to name individuals they thought smelled good or bad...
January 1, 2017: Perception
https://www.readbyqxmd.com/read/28043239/longitudinal-synergies-between-cortisol-reactivity-and-diurnal-testosterone-and-antisocial-behavior-in-young-adolescents
#3
Elizabeth J Susman, Melissa K Peckins, Jacey L Bowes, Lorah D Dorn
The aims were to identify the correspondence between simultaneous, longitudinal changes in cortisol reactivity and diurnal testosterone and to test the hypothesis that cortisol reactivity and diurnal testosterone interact so as to influence antisocial behavior. Participants were 135 children and young adolescents assessed at 6-month intervals over 1 year. Upon enrollment girls were age 8, 10, or 12 years (N = 69, M = 10.06 years) and boys were age 9, 11, or 13 years (N = 66, M = 10.94 years). Assessments included Tanner staging by a nurse, cortisol reactivity (Trier Social Stress Test for Children), diurnal testosterone, and interviews and questionnaires...
January 3, 2017: Development and Psychopathology
https://www.readbyqxmd.com/read/28038437/internalization-of-appearance-ideals-mediates-the-relationship-between-appearance-related-pressures-from-peers-and-emotional-eating-among-adolescent-boys-and-girls
#4
Katherine A Thompson, Nichole R Kelly, Natasha A Schvey, Sheila M Brady, Amber B Courville, Marian Tanofsky-Kraff, Susan Z Yanovski, Jack A Yanovski, Lauren B Shomaker
Appearance-related pressures have been associated with binge eating in previous studies. Yet, it is unclear if these pressures are associated with emotional eating or if specific sources of pressure are differentially associated with emotional eating. We studied the associations between multiple sources of appearance-related pressures, including pressure to be thin and pressure to increase muscularity, and emotional eating in 300 adolescents (Mage=15.3, SD=1.4, 60% female). Controlling for age, race, puberty, body mass index (BMI) z-score, and sex, both pressure to be thin and pressure to be more muscular from same-sex peers were positively associated with emotional eating in response to feeling angry/frustrated and unsettled (ps<0...
December 22, 2016: Eating Behaviors
https://www.readbyqxmd.com/read/28024271/the-impact-of-the-severity-of-early-life-stress-on-diurnal-cortisol-the-role-of-puberty
#5
Lucy S King, Natalie L Colich, Joelle LeMoult, Kathryn L Humphreys, Sarah J Ordaz, Alexandria N Price, Ian H Gotlib
Researchers have documented dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis in children and adolescents who experienced early life stress (ELS). The precise nature of this dysregulation, however, has been difficult to discern. In fact, both elevated and blunted patterns of diurnal cortisol regulation have been reported in children and adolescents exposed to greater ELS, including both reduced and heightened cortisol levels and change in cortisol across the day. These divergent findings may be due to developmental changes in the relation between ELS and HPA-axis functioning...
November 24, 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/27997352/transdermal-testosterone-gel-for-induction-and-continuation-of-puberty-in-adolescent-boys-with-hepatic-dysfunction
#6
Maria F Contreras, Manish Raisingani, Kris Prasad, Bonita Franklin, Bina Shah
Treatment to induce puberty in boys is indicated in those who do not undergo spontaneous development at a normal age. Stimulating development of the secondary sex characteristics is possible using gradually increasing doses of testosterone esters (TEs) via intramuscular (IM) administration, which is the most widely used method of testosterone (T) supplementation. When TEs are administered as monthly injection, serum T levels exhibit large fluctuations with supraphysiologic levels seen immediately after the injection followed by a decrease into the low range...
January 1, 2017: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/27993449/growth-and-final-height-of-children-with-gaucher-disease-a-15-year-follow-up-at-an-israeli-gaucher-center
#7
Espen Mendelsohn, Amos Meir, Aya Abrahamov, Deborah Elstein, Ari Zimran, Floris Levy-Khademi
BACKGROUND: It is held that enzyme replacement therapy (ERT) accelerates the growth rate in children with Gaucher disease, but its effect on final height has not been established with certainty. This study presents final heights of Gaucher patients followed up for 15years. METHODS: The study included 41 adults with non-neuronopathic Gaucher disease. The final height of the patients and age at puberty was compared to their mid-parental target height and to their siblings' heights...
December 9, 2016: Blood Cells, Molecules & Diseases
https://www.readbyqxmd.com/read/27992610/maternal-preeclampsia-and-androgens-in-the-offspring-around-puberty-a-follow-up-study
#8
Ingvild V Alsnes, Imre Janszky, Bjørn O Åsvold, Inger Økland, Michele R Forman, Lars J Vatten
BACKGROUND: Children born after preeclampsia may have a dominant androgen profile in puberty compared with other children. Circulating androgen concentrations at 11-12 years of age were compared between offspring born after preeclampsia, and children whose mothers did not have preeclampsia. METHODS: A total of 611 mother-offspring pairs were followed up 11 (daughters) or 12 (sons) years after birth: 218 pairs in the preeclampsia group, and 383 pairs without preeclampsia...
2016: PloS One
https://www.readbyqxmd.com/read/27988506/plasma-concentrations-of-osteocalcin-are-associated-with-the-timing-of-pubertal-progress-in-boys
#9
Michael M Schündeln, Lena Bäder, Cordula Kiewert, Ralf Herrmann, Dagmar Führer, Berthold P Hauffa, Corinna Grasemann
BACKGROUND: Animal models have shown that the skeletal hormone osteocalcin stimulates testicular testosterone synthesis. To assess whether osteocalcin might be a useful marker to detect pubertal development disorders, we examined osteocalcin plasma concentrations in children and adolescents with and without disorders of pubertal development. METHODS: Osteocalcin concentrations were investigated in a total of 244 patients with endocrine disorders (122 males, mean age: 11...
December 19, 2016: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/27982202/a-boy-with-prader-willi-syndrome-unmasking-precocious-puberty-during-growth-hormone-replacement-therapy
#10
Natasha G Ludwig, Rafael F Radaeli, Mariana M X Silva, Camila M Romero, Alexandre J F Carrilho, Danielle Bessa, Delanie B Macedo, Maria L Oliveira, Ana Claudia Latronico, Tânia L Mazzuco
Prader-Willi syndrome (PWS) is a genetic disorder frequently characterized by obesity, growth hormone deficiency, genital abnormalities, and hypogonadotropic hypogonadism. Incomplete or delayed pubertal development as well as premature adrenarche are usually found in PWS, whereas central precocious puberty (CPP) is very rare. This study aimed to report the clinical and biochemical follow-up of a PWS boy with CPP and to discuss the management of pubertal growth. By the age of 6, he had obesity, short stature, and many clinical criteria of PWS diagnosis, which was confirmed by DNA methylation test...
November 2016: Archives of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27979788/multivariate-dynamical-modelling-of-structural-change-during-development
#11
Gabriel Ziegler, Gerard R Ridgway, Sarah-Jayne Blakemore, John Ashburner, Will Penny
Here we introduce a multivariate framework for characterising longitudinal changes in structural MRI using dynamical systems. The general approach enables modelling changes of states in multiple imaging biomarkers typically observed during brain development, plasticity, ageing and degeneration, e.g. regional gray matter volume of multiple regions of interest (ROIs). Structural brain states follow intrinsic dynamics according to a linear system with additional inputs accounting for potential driving forces of brain development...
December 12, 2016: NeuroImage
https://www.readbyqxmd.com/read/27941749/central-precocious-puberty-a-case-report
#12
T Haq, A M Taib, S Ikhtaire
Precocious puberty in a male child is uncommon. Moreover, a predominantly luteinising hormone secreting pituitary tumor is rare. We report a case of predominantly luteinising hormone secreting pituitary adenoma causing precocious puberty in a three year old boy. A thorough systematic investigation including serum gonadotropins and imaging should be done to search for an underlying cause, even in the absence of pressure symptoms. Surgery with long term follow up is the recommended treatment for functioning gonadotrophin tumors...
October 2016: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/27940757/atypical-leydig-cell-tumor-in-children-report-of-2-cases
#13
Chiara Mameli, Giorgio Selvaggio, Chiara Cerini, Gaetano Bulfamante, Cristina Madia, Giovanna Riccipetitoni, Gian Vincenzo Zuccotti
Leydig cell tumors (LCTs) are rare cord-stromal tumors that may occur in testis or ovaries and may produce androgens or estrogens. The majority has been found in men between the ages of 20 and 60 years. Adults with androgen-secreting LCTs are usually asymptomatic; feminizing syndromes may result from the production of estradiol or the peripheral aromatization of testosterone. In children, LCTs usually present between 5 and 10 years of age with isosexual precocious pseudopuberty or gynecomastia. We report 2 cases of LCT in prepubertal boys presenting with advanced unilateral pubarche and testicular volume asymmetry...
November 2016: Pediatrics
https://www.readbyqxmd.com/read/27939363/sex-differences-in-biological-response-to-peer-rejection-and-performance-challenge-across-development-a-pilot-study
#14
Laura R Stroud, George D Papandonatos, Christina M D'Angelo, Bridget Brush, Elizabeth E Lloyd-Richardson
A pilot study of sex differences in biological response to peer rejection and performance challenges across development was conducted. Participants were 59 typically-developing children (ages 8-17; 58% girls); 59 children completed one challenge: 37 completed both challenges. Following a habituation session, participants completed peer rejection (exclusion challenges) and/or performance (speech, arithmetic, tracing) stress sessions. Saliva cortisol and alpha amylase (AA) were measured throughout. Post-pubertal girls showed increased AA and equivalent cortisol output in response to rejection vs...
February 1, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/27933566/fracture-incidence-rates-in-norwegian-children-the-troms%C3%A3-study-fit-futures
#15
Tore Christoffersen, Luai A Ahmed, Anne Winther, Ole Andreas Nilsen, Anne-Sofie Furberg, Guri Grimnes, Elaine Dennison, Jacqueline R Center, John A Eisman, Nina Emaus
: This study describes childhood fracture rates in Norway, a country known for high fracture rates in the adult population. Fracture rates correspond with other reports from Scandinavia, although with a slightly higher proportion in girls. Indications of increased vulnerability during stages of puberty require further exploration. INTRODUCTION: Fractures are common injuries during childhood. Incidence rates and patterns vary, but population-based data are scarce...
December 2016: Archives of Osteoporosis
https://www.readbyqxmd.com/read/27931171/-behaving-well-the-transition-to-respectable-womanhood-in-rural-south-africa
#16
Christie Sennott, Sanyu A Mojola
Few studies of the transition to adulthood in Africa analyse young people's own definitions of the events that confer adult status, and how adulthood is actually attained. This paper examines the experience of transitioning to womanhood in rural Mpumalanga Province, South Africa, drawing on interviews with 18 women aged 18-39. Three primary experiences characterised this transition: puberty and emerging body awareness, spending time with boys, and having a child. More important than the timing of these experiences, however, was whether women 'behaved well' and maintained respectability as they transitioned to adulthood...
December 9, 2016: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/27927844/congenital-hypogonadotropic-hypogonadism-functional-hypogonadotropism-or-constitutional-delay-of-growth-and-puberty-an-analysis-of-a-large-patient-series-from-a-single-tertiary-center
#17
Tero Varimo, Päivi J Miettinen, Johanna Känsäkoski, Taneli Raivio, Matti Hero
STUDY QUESTION: What diagnoses underlie delayed puberty (DP) and predict its outcome? SUMMARY ANSWER: A multitude of different diagnoses underlie DP, and in boys a history of cryptorchidism, small testicular size and slow growth velocity (GV) predict its clinical course. WHAT IS KNOWN ALREADY: DP is caused by a variety of underlying etiologies. Hormonal markers can be used in the differential diagnosis of DP but none of them have shown complete diagnostic accuracy...
January 2017: Human Reproduction
https://www.readbyqxmd.com/read/27903360/-update-on-pubertal-development-among-primary-school-students-in-shanghai-2014
#18
Y Chen, Y T Zhang, C Chen, Y R Jiang, Y J Song, S J Liu, F Jiang
Objective: To investigate the current prevalence of pubertal development in healthy Shanghai schoolchildren. Methods: This study was a cross-sectional investigation focused on current pubertal development conducted in healthy Shanghai schoolchildren by multi-stage cluster sampling. The sample included 17 571 children in grades 1-5 investigated in June 2014. The data were weighted by inverse probability weighting (IPW) to make them more representative. At examination, stages of breast and pubic hair development were rated according to the Tanner method...
November 6, 2016: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/27890604/gender-dimorphism-in-pediatric-osa-is-it-for-real
#19
REVIEW
Pablo E Brockmann, Dorit Koren, Leila Kheirandish-Gozal, David Gozal
In epidemiologic studies focused on adults, obstructive sleep apnea (OSA) has higher prevalence in men than in women. The evidence supporting a gender-related discrepant prevalence of OSA is however much more tenuous in children. Here, we aimed to review the evidence concerning gender- based differences in the prevalence of OSA in children, and if so, to examine the evidence with the intent to identify potential factors that may account for this putative association. Gender-based perception and reporting of clinical manifestations of OSA may be modulated by several social and cultural factors in children...
November 23, 2016: Respiratory Physiology & Neurobiology
https://www.readbyqxmd.com/read/27889727/longitudinal-growth-in-children-and-adolescents-with-type-1-diabetes
#20
Lavanya Parthasarathy, Vaman Khadilkar, Shashi Chiplonkar, Anuradha Khadilkar
OBJECTIVE: To study longitudinal growth in children with type 1 diabetes mellitus. METHODS: Anthropometry, disease duration, insulin regimens and HbA1C recorded from patients with diabetes enrolled in a specialty clinic. RESULTS: 160 children (75 boys; mean (SD) age 9.4 (3.3) y) were enrolled. 35% children had low (<25th centile) height velocity. Disease duration and HbA1C affected height velocity (adjusted for puberty). Children on basal-bolus had higher height velocity Z scores than those on a split mix regimen [(0...
November 15, 2016: Indian Pediatrics
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