keyword
MENU ▼
Read by QxMD icon Read
search

B12

keyword
https://www.readbyqxmd.com/read/29457932/oral-health-related-outcomes-in-edentulous-patients-treated-with-mandibular-implant-retained-dentures-versus-complete-dentures-systematic-review-with-meta-analyses
#1
Philip Kroll, Lisa Hou, Hani Radaideh, Nazanin Sharifi, Phuu P Han, Roseann Mulligan, Reyes Enciso
The objective of this systematic review was to determine the effect on oral health-related outcomes from mandibular implant-retained dentures opposing maxillary complete dentures in edentulous middle-age and older adults compared to complete removable dentures in both arches. Randomized controlled trials with an average age of the participants being 65 years old or above were included. The Cochrane Library, MEDLINE and Web of Science were searched. A total of 228 abstracts were reviewed for inclusion criteria with fourteen trials included and analyzed for risk of bias...
February 19, 2018: Journal of Oral Implantology
https://www.readbyqxmd.com/read/29457884/unique-biochemical-and-sequence-features-enable-blub-to-destroy-flavin-and-distinguish-blub-from-the-flavin-monooxygenase-superfamily
#2
Amrita B Hazra, David P Ballou, Michiko E Taga
Vitamin B12 (cobalamin) is an essential micronutrient for humans that is synthesized only by a subset of bacteria and archaea. The aerobic biosynthesis of 5,6-dimethylbenzimidazole, the lower axial ligand of cobalamin is catalyzed by the "flavin destructase" enzyme BluB, which fragments reduced flavin mononucleotide following its reaction with oxygen to yield this ligand. BluB shares sequence and structural similarity with the flavin oxidoreductase superfamily, yet the flavin destruction process has remained elusive...
February 19, 2018: Biochemistry
https://www.readbyqxmd.com/read/29457678/micronutrients-dietary-patterns-associated-with-type-2-diabetes-among-women-of-the-e3n-epic-cohort-study
#3
Francesca Romana Mancini, Courtney Dow, Aurélie Affret, Kalina Rajaobelina, Laureen Dartois, Beverley Balkau, Fabrice Bonnet, Marie-Christine Boutron-Ruault, Guy Fagherazzi
BACKGROUND: Micronutrients play a key role in type 2 diabetes, but methodological difficulties arise from their collinearity and interdependencies with foods. The objective of the present study is to identify micronutrient dietary patterns in the E3N-EPIC cohort and to investigate their association with type 2 diabetes risk. METHODS: Principal component analysis was applied to identify micronutrient patterns among 71 270 women from the E3N-EPIC cohort. Associations between micronutrient patterns and type 2 diabetes risk were quantified by hazards ratios (95% confidence intervals) from Cox proportional hazards regression models, adjusted on potential confounders...
February 19, 2018: Journal of Diabetes
https://www.readbyqxmd.com/read/29456691/different-doses-of-folic-acid-and-vitamin-b12-to-treat-rabbits-with-deep-venous-thrombosis-and-hyperhomocysteinemia
#4
Xiao-Jun Shu, Zheng-Fei Li, Yao-Wen Chang, Sheng-Ye Liu, Wen-Hui Wang, Xiaoqiang Li
The effects of different doses of folic acid and vitamin B12 on rabbits with deep vein thrombosis (DVT) and hyperhomocysteinemia were investigated. In total, 60 New Zealand rabbits were divided into untreated control, low-dose and high-dose groups. After inducing DVT, hemorheology and coagulation indexes were measured 3 and 10 days later. We found that both treatment groups performed better than the control group, and the high-dose performed better than the low-dose. Ten days after thrombosis, the levels of Hcy and D-dimer were lower in the high-dose group...
March 2018: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29454538/cobalamin-deficiency-presenting-with-thrombotic-microangiopathy-tma-features-a-systematic-review
#5
Phu Ngoc Tran, Minh-Ha Tran
INTRODUCTION: Cobalamin deficiency may result in hematologic characteristics similar to thrombotic microangiopathy (TMA). To facilitate diagnosis, we reviewed reported cases of acquired cobalamin deficiency presenting with TMA features (c.def-TMA). METHODS: A literature search identified reports of c.def-TMA. Deficiency was defined as B12 levels of <118 pmol/L. Corrected reticulocyte counts and reticulocyte production indexes were calculated. Clinical features were presented as proportion abnormal and results summarized as medians and interquartile ranges (IQR)...
January 11, 2018: Transfusion and Apheresis Science
https://www.readbyqxmd.com/read/29447493/vitamin-d-and-ferritin-correlation-with-chronic-neck-pain-using-standard-statistics-and-a-novel-artificial-neural-network-prediction-model
#6
Haytham Eloqayli, Ali Al-Yousef, Raid Jaradat
AIM: Despite the high prevalence of chronic neck pain, there is limited consensus about the primary etiology, risk factors, diagnostic criteria and therapeutic outcome. Here, we aimed to determine if Ferritin and Vitamin D are modifiable risk factors with chronic neck pain using slandered statistics and artificial intelligence neural network (ANN). METHODS: Fifty-four patients with chronic neck pain treated between February 2016 and August 2016 in King Abdullah University Hospital and 54 patients age matched controls undergoing outpatient or minor procedures were enrolled...
February 15, 2018: British Journal of Neurosurgery
https://www.readbyqxmd.com/read/29446340/identification-of-vitamin-b12-deficiency-in-vegetarian-indians
#7
Sadanand Naik, Namita Mahalle, Vijayshri Bhide
The prevalence of a sub-clinical vitamin B12 deficiency in the vegetarians is high. Total serum vitamin B12 concentration alone does not reliably reflect vitamin B12 status. Holotranscobalamin (holo-TC) II is a bioactive B12 fraction promoting specific uptake of B12 by cells and the circulating concentration reflects the intake of B12, whereas total homocysteine (tHcy) indicates the metabolic ability. In this study, we investigated the diagnostic value of circulating holo-TC, B12, folate and homocysteine in vegetarians who were at risk of B12 deficiency...
February 15, 2018: British Journal of Nutrition
https://www.readbyqxmd.com/read/29446079/dietary-intake-of-nutrients-involved-in-one-carbon-metabolism-and-risk-of-urothelial-cell-carcinoma-a-prospective-cohort-study
#8
Pierre-Antoine Dugué, Maree T Brinkman, Allison M Hodge, Julie K Bassett, Damien Bolton, Anthony Longano, John L Hopper, Melissa C Southey, Dallas R English, Roger L Milne, Graham G Giles
Nutrients involved in one-carbon metabolism may play a role in carcinogenesis through DNA replication, repair and methylation mechanisms. Most studies on urothelial cell carcinoma (UCC) have focused on folate. We sought to examine the association between B-group vitamins and methionine intake and UCC risk, overall and by subtype, and to test whether these associations are different for population subgroups whose nutritional status may be compromised. We followed participants in the Melbourne Collaborative Cohort Study (N=41,513) for over 20 years, and observed 500 UCC cases (89% originating in the bladder; superficial: 279, invasive: 221)...
February 15, 2018: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/29445423/an-update-on-vitamin-b12-related-gene-polymorphisms-and-b12-status
#9
REVIEW
S Surendran, A Adaikalakoteswari, P Saravanan, I A Shatwaan, J A Lovegrove, K S Vimaleswaran
Background: Vitamin B12 is an essential micronutrient in humans needed for health maintenance. Deficiency of vitamin B12 has been linked to dietary, environmental and genetic factors. Evidence for the genetic basis of vitamin B12 status is poorly understood. However, advancements in genomic techniques have increased the knowledge-base of the genetics of vitamin B12 status. Based on the candidate gene and genome-wide association (GWA) studies, associations between genetic loci in several genes involved in vitamin B12 metabolism have been identified...
2018: Genes & Nutrition
https://www.readbyqxmd.com/read/29445184/parental-micronutrient-deficiency-distorts-liver-dna-methylation-and-expression-of-lipid-genes-associated-with-a-fatty-liver-like-phenotype-in-offspring
#10
Kaja H Skjærven, Lars Martin Jakt, Jorge M O Fernandes, John Arne Dahl, Anne-Catrin Adam, Johanna Klughammer, Christoph Bock, Marit Espe
Micronutrient status of parents can affect long term health of their progeny. Around 2 billion humans are affected by chronic micronutrient deficiency. In this study we use zebrafish as a model system to examine morphological, molecular and epigenetic changes in mature offspring of parents that experienced a one-carbon (1-C) micronutrient deficiency. Zebrafish were fed a diet sufficient, or marginally deficient in 1-C nutrients (folate, vitamin B12, vitamin B6, methionine, choline), and then mated. Offspring livers underwent histological examination, RNA sequencing and genome-wide DNA methylation analysis...
February 14, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29442401/single-arm-phase-ii-study-of-oral-vitamin-b12-for-the-treatment-of-musculoskeletal-symptoms-associated-with-aromatase-inhibitors-in-women-with-early-stage-breast-cancer
#11
Aleli Campbell, Rosalinda Heydarian, Cecilia Ochoa, Alok Kumar Dwivedi, Zeina A Nahleh
Breast cancer patients receiving endocrine therapy with aromatase Inhibitors (AIs) often experience musculoskeletal and joint-related side effects. The purpose of this study was to evaluate the effect of Vitamin B12 supplements on musculoskeletal symptoms such as pain and arthralgias induced by AIs and to correlate response with serum and inflammatory biomarkers. Upon receiving approval by the Institutional Review Board (IRB), the majority of the patients consented into the study were treated at the Texas Tech Breast Care Center...
February 14, 2018: Breast Journal
https://www.readbyqxmd.com/read/29433755/vitamin-mineral-and-micronutrient-status-in-patients-with-classical-phenylketonuria
#12
Engin Kose, Nur Arslan
BACKGROUND & AIMS: Strict low-phenylalanine diet is associated with an increased risk of developing micronutrient deficiencies in patients with phenylketonuria (PKU). The primary objective of this single-center, case-control study was to assess the nutritional parameters of patients with PKU on strict low-phenylalanine diet without vitamin and mineral supplementation compared to a healthy control group. Secondary objective was to identify the adequacy of vitamin/mineral supplementation in phenylalanine-free (Phe-free) amino acid formulas...
February 9, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29433230/in-vitro-digestion-behavior-of-water-in-oil-in-water-emulsions-with-gelled-oil-water-inner-phases
#13
Jonathan Andrade, Amanda J Wright, Milena Corredig
Double emulsions may be able to protect and release in a controlled manner bioactive compounds during digestion of food matrices. It was hypothesized that the physical state and solid content in the inner phases of water-in-oil-in-water (W1/O/W2) emulsions may affect the overall stability and the release behavior of bioactives during in vitro digestion. Therefore, hydrophobic (phytosterols or Vitamin D3) and hydrophilic (Vitamin B12) molecules were incorporated in double emulsions prepared either with a liquid (soybean oil - SO) or oil-fat gel (soybean oil+trimyristin - STO) lipid phase and liquid internal aqueous phase...
March 2018: Food Research International
https://www.readbyqxmd.com/read/29425476/scottsdale-magnesium-study-absorption-cellular-uptake-and-clinical-effectiveness-of-a-timed-release-magnesium-supplement-in-a-standard-adult-clinical-population
#14
Decker Weiss, Debra K Brunk, Dennis A Goodman
OBJECTIVE: Suboptimal magnesium status is likely widespread in the United States and increasing evidence links it to many chronic diseases. Therapeutically addressing magnesium status can be challenging, as higher supplementation often leads to bowel intolerance. This study evaluated the absorption, cellular uptake, and clinical effectiveness of a timed-release formulation containing dimagnesium malate with vitamins B6, B12, and folate (MagSRT™) in a standard clinical population. METHODS: A standard clinical population of 91 adults participated in a placebo-controlled study carried out at two clinics; 53 individuals received MagSRT™, containing 500 mg dimagnesium malate and vitamins B6, B12, and folate, while the remaining individuals received a placebo...
February 9, 2018: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/29423219/the-effect-of-protein-supplementation-on-body-muscle-mass-and-fat-mass-in-post-bariatric-surgery-a-randomized-controlled-trial-rct-study-protocol
#15
Sahar D Al-Shamari, Mohamed Aly ElSherif, Wahiba Hamid, Fahad Hanna
Background: Severe weight loss through means of bariatric surgery has been associated with loss of muscle mass due to lack of absorption of protein. The aim of this RCT is to investigate the effectiveness of protein supplementation in reducing the risk of developing protein malnutrition and muscle wasting in post-bariatric surgery patients in Qatar. Methods and analysis: The study was based at the Department of bariatric and metabolic surgery, Doha metropolitan and regional areas...
2018: Archives of Public Health, Archives Belges de Santé Publique
https://www.readbyqxmd.com/read/29422355/infantile-tremor-syndrome-response-to-b12-therapy
#16
Indar Kumar Sharawat, Ananthanarayanan Kasinathan, Naveen Sankhyan
No abstract text is available yet for this article.
February 6, 2018: Journal of Pediatrics
https://www.readbyqxmd.com/read/29422004/vitamin-d-and-subjective-memory-complaint-in-community-dwelling-older-adults
#17
Cedric Annweiler, Lise Doineau, Lucie Gerigne, Anais Provendier, Spyridon N Karras, Olivier Beauchet, Bruno Fantino, Guillaume T Duval
BACKGROUND: Older adults with hypovitaminosis D report more often subjective cognitive complaints, especially with regards to memory. This raises prospects that vitamin D may improve older adults' subjective experience of memory disorders. OBJECTIVE: To determine among older community-dwellers whether higher serum 25-hydroxyvitamin D (25OHD) concentrations were associated with fewer memory complaints, while considering the different subtypes of memory complaints...
February 1, 2018: Current Alzheimer Research
https://www.readbyqxmd.com/read/29416583/assessment-of-serum-vitamin-b12-levels-and-other-metabolic-parameters-in-subjects-with-different-values-of-bone-mineral-density
#18
Marianna Renis, Debora Lobreglio, Pierpaolo Congedo, Maria Concetta Montinaro, Maurizio Muratore, Giambattista Lobreglio
Background: Controversial experimental and clinical evidences have raised questions regarding the role of B12 and insulin-like growth factor 1 (IGF-1) on osteoblast function and bone health. In this study, we aimed to determine if the serum levels of B12, IGF-1 and procollagen type 1 N-terminal propeptide (P1NP) are associated with different degrees of bone mineral density (BMD). Methods: A total of 287 subjects (190 women and 97 men; mean age 53 years) volunteered for evaluation of BMD and serum levels of B12, IGF-1 and P1NP; BMD at lumbar spine and proximal femur was evaluated by means of dual-energy X-ray absorption (DEXA) and expressed as T-score; serum concentrations of vitamin B12 and IGF1 were measured with a chemiluminescent immunoassay on Access II Beckman Coulter and DiaSorin Liaison XL analyzers, respectively; P1NP was assessed in 61 women and 35 men with reduced T-score on Roche Modular platform...
March 2018: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/29415843/association-between-nutrient-patterns-and-bone-mineral-density-among-ageing-adults
#19
Yohannes Adama Melaku, Tiffany K Gill, Anne W Taylor, Robert Adams, Zumin Shi
BACKGROUND AND AIM: There is limited evidence on the link between the overall nutrients intake from diet and bone mineral density (BMD). We assessed the association between nutrient patterns and BMD among an ageing Australian population. METHODS: Participants (n = 1135; males, 45.8%; median age, 62.0 years) with dietary and BMD data in the North West Adelaide Health Study (NWAHS) were included. Dietary intake was assessed using a food frequency questionnaire. BMD was measured using dual-energy X-ray absorptiometry...
December 2017: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29415587/an-evaluation-of-nutritional-and-vasoactive-stimulants-as-risk-factors-for-gastroschisis-a-pilot-study
#20
Jean R Goodman, Jennifer D Peck, Alessandra Landmann, Marvin Williams, Andrew Elimian
OBJECTIVE: The objective of this study is to evaluate poor maternal nutrition, environmental exposures and vasoactive stimulants as potential risk factors for gastroschisis. METHODS: A case-control study was conducted among singleton pregnancies diagnosed in a tertiary teaching hospital in a 22-month period. Cases of gastroschisis were matched to controls at the time of diagnosis by race and maternal age. Demographics, periconceptual exposures, nutritional biomarkers, and illicit drug hair analysis were evaluated...
February 7, 2018: Journal of Maternal-fetal & Neonatal Medicine
keyword
keyword
3153
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"