Xin Li, Jiang-Shan Tan, Jing Xu, Zhihui Zhao, Qing Zhao, Yi Zhang, Anqi Duan, Zhihua Huang, Sicheng Zhang, Luyang Gao, Yue Jin Yang, Tao Yang, Qi Jin, Qin Luo, Yanmin Yang, Zhihong Liu
BACKGROUND: Patients with pulmonary arterial hypertension (PAH) exhibit a distinct gut microbiota profile; however, the causal association between gut microbiota, associated metabolites, and PAH remains elusive. We aimed to investigate this causal association and to explore whether dietary patterns play a role in its regulation. METHODS: Summary statistics of gut microbiota, associated metabolites, diet, and PAH were obtained from genome-wide association studies...
April 17, 2024: BMC Pulmonary Medicine