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pancoast syndrome

Kyong-Hee Lee, Kiyozumi Suzuki, Masashi Tsuru, Arifumi Takazawa
No abstract text is available yet for this article.
January 25, 2018: Infection
Rajanshu Verma, Alexandra Lambert, Harold H Katz, Scott J Benson
We present an interesting case where a patient is presented with a droopy left eyelid (as part of Horner syndrome) and Cushingoid features which were a result of a Pancoast tumour (apical lung tumour in superior pulmonary sulcus) involving the left lung. This tumour was secreting ectopic adrenocorticotropic hormone (ACTH), a paraneoplastic endocrine phenomenon, which resulted in Cushing syndrome symptomatology. Though most ectopic ACTH-producing lung cancers are either small cell or carcinoid tumours, this was in fact a large cell neuroendocrine cancer (LCNEC)...
March 24, 2017: BMJ Case Reports
Vasa Jevremovic, Adnan Yousuf, Zulfiqar Hussain, Amer Abboud, Edgar G Chedrawy
BACKGROUND: Myxofibrosarcoma is an aggressive soft tissue neoplasm, classified as a variant of malignant fibrous histiocytoma. Most often, it occurs in middle to late adult life peaking in the seventh decade and involving the lower extremities (77%), trunk (12%), and retroperitoneum or mediastinum (8%). We report the first case of thoracic myxofibrosarcoma presenting as a Pancoast tumor. CASE PRESENTATION: A 48-year-old non-tobacco smoking African-American man presented with a slow-growing mass in his neck along with 11 kg weight loss over 9 months...
March 7, 2017: Journal of Medical Case Reports
M Zysman, C Clement-Duchene, C Bastien, P Vaillant, Y Martinet
INTRODUCTION: Rhabdoid tumours usually develop in brain and spinal cord or kidney; they are highly malignant neoplasms that typically arise in infancy and early childhood. However, rare cases of pulmonary localization have been described, particularly among young adults. CASE REPORT: A 26-year-old man, smoker, had a right apical lung mass associated with a Pancoast syndrome leading to haemoptysis. There was also a tumour of the left thigh and scalp. Histological samples taken at these three locations were in favour of an undifferentiated carcinoma...
November 2016: Revue des Maladies Respiratoires
Aliena Badshah, Salman Khan, Usman Saeed
This report describes a patient who presented with pancoast syndrome, secondary to spindle cell sarcoma of the lung. A 56-year man presented with dyspnea, engorged neck veins and bilateral upper limb pitting edema. The patient also had ptosis and miosis in the right eye. Right ulnar nerve palsy with atrophy of hand muscles was seen. His chest X-ray showed bilateral pleural effusion with an opacity involving the apex of the right lung along with mediastinal widening. Echocardiography revealed a pericardial effusion which was drained...
July 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
Giuseppe Marulli, Lucia Battistella, Marco Mammana, Francesca Calabrese, Federico Rea
Superior Sulcus Tumors, frequently termed as Pancoast tumors, are a wide range of tumors invading the apical chest wall. Due to its localization in the apex of the lung, with the potential invasion of the lower part of the brachial plexus, first ribs, vertebrae, subclavian vessels or stellate ganglion, the superior sulcus tumors cause characteristic symptoms, like arm or shoulder pain or Horner's syndrome. The management of superior sulcus tumors has dramatically evolved over the past 50 years. Originally deemed universally fatal, in 1956, Shaw and Paulson introduced a new treatment paradigm with combined radiotherapy and surgery ensuring 5-year survival of approximately 30%...
June 2016: Annals of Translational Medicine
Melissa McLenon, Gregory J Bittle, Kevin Jones, Jay Menaker, Si M Pham, Aldo T Iacono, Ashutosh Sachdeva, Keshava Rajagopal
Venovenous (V-V) extracorporeal membrane oxygenation (ECMO) is used for respiratory failure that is suspected to be reversible (bridge to recovery), or as a bridge to lung transplantation. Patients with proximal airway obstruction due to endobronchial malignancy can develop acute respiratory failure, and may benefit from V-V ECMO as a bridge to airway intervention, further treatment, and eventual recovery. We describe a case of a superior sulcus tumor with tracheobronchial and superior vena cava invasion causing both respiratory failure and superior vena cava syndrome...
July 2016: Annals of Thoracic Surgery
Lorenzo Rosso, Alessandro Palleschi, Paolo Mendogni, Mario Nosotti
BACKGROUND: The mini-ivasive approach to superior sulcus tumors is an uncommon procedure that is still far from standardization. We describe a hybrid surgical technique to approach "en block" chest resection and pulmonary lobectomy for anterior superior sulcus tumors. CASE PRESENTATION: A patient affected by right anterior Pancoast tumor surgically staged as cT4N0M0 (suspected anonymous vein invasion) underwent chemo-radiation induction therapy with satisfactory tumor reduction...
April 14, 2016: Journal of Cardiothoracic Surgery
Amit S Padaki, R Warne Fitch, Lawrence B Stack, R Jason Thurman
BACKGROUND: Horner's syndrome refers to the clinical triad of ptosis, miosis, and anhidrosis resulting from disruption of the ocular and facial sympathetic pathways. A myriad of etiologies can lead to Horner's syndrome; awareness of the underlying anatomy can assist physicians in identifying potential causes and initiating appropriate care. CASE REPORT: Two patients presented to our Nashville-area hospital in 2014. Patient 1 was a 26-year-old man who noticed facial asymmetry one day after an outpatient orthopedic procedure...
May 2016: Journal of Emergency Medicine
Faisal R Jahangiri
This case illustrates the benefits of utilizing intraoperative neurophysiological monitoring (IONM) for preventing injury to sensory/motor pathways of the spinal cord during a cordotomy procedure to relieve pain. Cordotomy has been used effectively in the treatment of visceral pain but comes with a high risk of damaging motor and sensory pathways due to close proximity of lesion. The subject is a 47-year-old female with a pancoast tumor of the left lung, left brachialplexopathy, and severe neuropathic pain syndrome, refractory to medical therapy...
September 2015: Neurodiagnostic Journal
S Rabiou, I Issoufou, L Belliraj, F Z Ammor, M Lakranbi, Y Ouadnouni, M Smahi
No abstract text is available yet for this article.
May 2016: QJM: Monthly Journal of the Association of Physicians
Anirban Das, Sabyasachi Choudhury, Sumitra Basuthakur, Sibes Kumar Das, Angshuman Mukhopadhyay
Malignant tumours in the apices of the lungs, especially bronchogenic carcinoma (Pancoast tumours), are the most common cause of Pancoast' syndrome which presents with shoulder or arm pain radiating along the medial aspect of forearm and weakness of small muscles of hand with wasting of hypothenar eminence due to neoplastic involvement of C8 and T1 and T2 nerve roots of brachial plexus. There are a number of benign conditions which may lead to Pancoast's syndrome; fungal abscess located in the apex of lung is one of them...
2014: Case Reports in Pulmonology
A-L Clause, K Vanderheyde, T Pieters
INTRODUCTION: Erlotinib, an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), is a targeted therapy used in first, second or third line treatment of non-small cell lung carcinoma. Several cutaneous toxicities after the use of EGFR-TKI are well-described. OBSERVATION: After 13 days of erlotinib treatment, an 82-year-old man, diagnosed with squamous cell lung carcinoma, developed an acneiform rash in parallel with hand-foot syndrome (HFS). This led to the interruption of his treatment because of the patient's distress...
September 2014: Revue des Maladies Respiratoires
J A Hermida Péreza, A Bermejo Hernández, J S Hernández Guerra, R Arroyo Diaz
We describe a clinical case of an 80 year-old woman, with a history of Alzheimer's disease, who presented with right shoulder pain, numbness and decreased strength in the right arm, with right eye ptosis, cough and dysphagia. The chest X-Ray and thoracic-abdominal computed tomography scan showed a large mass in the upper lobe and apex of the right lung, supraclavicular metastatic lymph nodes. In the fine needle aspiration biopsy: poorly differentiated non-small cell carcinoma. She was referred to Oncology to start chemotherapy treatment...
March 2012: Semergen
Panagopoulos Nikolaos, Livaditis Vasilios, Koletsis Efstratios, Alexopoulos Panagiotis, Prokakis Christos, Baltayiannis Nikolaos, Hatzimichalis Antonios, Kosmas Tsakiridis, Paul Zarogoulidis, Konstantinos Zarogoulidis, Nikolaos Katsikogiannis, Ioanna Kougioumtzi, Nikolaos Machairiotis, Theodora Tsiouda, Nikolaos Machairiotis, Athanasios Madesis, Georgios Vretzakis, Alexandros Kolettas, Dougenis Dimitrios
A Pancoast tumor, also called a pulmonary sulcus tumor or superior sulcus tumor, is a tumor of the pulmonary apex. It is a type of lung cancer defined primarily by its location situated at the top end of either the right or left lung. It typically spreads to nearby tissues such as the ribs and vertebrae. Most Pancoast tumors are non-small cell cancers. The growing tumor can cause compression of a brachiocephalic vein, subclavian artery, phrenic nerve, recurrent laryngeal nerve, vagus nerve, or, characteristically, compression of a sympathetic ganglion resulting in a range of symptoms known as Horner's syndrome...
March 2014: Journal of Thoracic Disease
Nikolaos Panagopoulos, Vasilios Leivaditis, Efstratios Koletsis, Christos Prokakis, Panagiotis Alexopoulos, Nikolaos Baltayiannis, Antonios Hatzimichalis, Kosmas Tsakiridis, Paul Zarogoulidis, Konstantinos Zarogoulidis, Nikolaos Katsikogiannis, Ioanna Kougioumtzi, Nikolaos Machairiotis, Theodora Tsiouda, Georgios Kesisis, Stavros Siminelakis, Athanasios Madesis, Dimitrios Dougenis
Superior sulcus tumors (SSTs), or as otherwise known Pancoast tumors, make up a clinically unique and challenging subset of non-small cell carcinoma of the lung (NSCLC). Although the outcome of patients with this disease has traditionally been poor, recent developments have contributed to a significant improvement in prognosis of SST patients. The combination of severe and unrelenting shoulder and arm pain along the distribution of the eighth cervical and first and second thoracic nerve trunks, Horner's syndrome (ptosis, miosis, and anhidrosis) and atrophy of the intrinsic hand muscles comprises a clinical entity named as "Pancoast-Tobias syndrome"...
March 2014: Journal of Thoracic Disease
Khaldoon Shaheen, Abdul Hamid Alraiyes, Motaz Baibars, Naseem Eisa, M Chadi Alraies
CONTEXT: The key clinical features in this case are to make the diagnosis apical lung cancer (Pancoast tumor) in a patient with brachial plexopathy and to recognize the association between syndrome of inappropriate secretion of antidiuretic hormone (SIADH) as a paraneoplastic syndrome and non-small cell lung cancer (NSCLC). CASE REPORT: We herein describe a rare case of NSCLC presented as pancoast tumor complicated by brachial plexopathy and associated with SIADH as a paraneoplastic phenomena...
November 2013: North American Journal of Medical Sciences
Christophoros N Foroulis, Paul Zarogoulidis, Kaid Darwiche, Nikolaos Katsikogiannis, Nikolaos Machairiotis, Ilias Karapantzos, Kosmas Tsakiridis, Haidong Huang, Konstantinos Zarogoulidis
Pancoast tumors account for less than 5% of all bronchogenic carcinomas. These tumors are located in the apex of the lung and involve through tissue contiguity the apical chest wall and/or the structures of the thoracic inlet. The tumors become clinically evident with the characteristic symptoms of the "Pancoast-Tobias syndrome" which includes Claude-Bernard-Horner syndrome, severe pain in the shoulder radiating toward the axilla and/or scapula and along the ulnar distribution of the upper arm, atrophy of hand and arm muscles and obstruction of the subclavian vein resulting in edema of the upper arm...
September 2013: Journal of Thoracic Disease
Anirban Sarkar, Anirban Das, Sumitra Basuthakur, Sudipta Pandit, Sibes K Das, Sabyasachi Choudhury
Pancoast syndrome is a common presentation of bronchogenic carcinoma, but other malignancies are rarely cited as its cause. Pancoast syndrome due to non-Hodgkin's lymphoma is rarely described in the literature. Here, we report a case of Pancoast syndrome due to non-Hodgkin's lymphoma to increase the awareness of the clinicians regarding essentiality of tissue diagnosis of Pancoast tumor before starting the treatment.
July 2013: Lung India: Official Organ of Indian Chest Society
Jean Deslauriers, François Tronc, Dalilah Fortin
Bronchogenic carcinomas involving the chest wall include tumors invading the ribs and spine, as well as Pancoast tumors. In the past, such neoplasms were considered to be incurable, but with new multimodality regimens, including induction chemoradiation followed by surgery, they can now be completely resected and patients can benefit from prolonged survival. The most important prognostic factors are the completeness of resection and the pathologic nodal status.
August 2013: Thoracic Surgery Clinics
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