keyword
MENU ▼
Read by QxMD icon Read
search

LPC

keyword
https://www.readbyqxmd.com/read/29122443/identification-of-serum-metabolites-associated-with-obesity-and-traditional-risk-factors-for-metabolic-disease-in-chinese-adults
#1
S M Wang, R Y Yang, M Wang, F S Ji, H X Li, Y M Tang, W X Chen, J Dong
BACKGROUND AND AIMS: Obesity is a major worldwide health problem and is often associated with many metabolic diseases. Levels of several serum-specific metabolites may be altered in patients with these metabolic diseases. We aimed to investigate the associations of serum metabolite levels with obesity and traditional risk factors for metabolic disease in Chinese individuals. METHODS AND RESULTS: Six-hundred Chinese individuals undergoing annual physical exams were recruited and categorized into overweight/obese and control groups (1:1 ratio)...
October 3, 2017: Nutrition, Metabolism, and Cardiovascular Diseases: NMCD
https://www.readbyqxmd.com/read/29120775/preparation-and-prebiotic-potential-of-pectin-oligosaccharides-obtained-from-citrus-peel-pectin
#2
Shanshan Zhang, Haijuan Hu, Lufeng Wang, Fengxia Liu, Siyi Pan
Pectin oligosaccharide (POS) fractions were obtained by controlled chemical degradation of citrus peel pectin. By adjusting trifluoroacetic acid (TFA) concentration, three oligosaccharides were obtained, of molecular weight (Mw) range 3000-4000 Da, 2000-3000 Da and lower than 2000 Da. Varying hydrogen peroxide (H2O2) concentration and reaction time produced oligosaccharides of 3000-4000 Da and 2000-3000 Da. The relative proportions of acidic monosaccharide increased from 68.58% to 89.93% (TFA) and from 63...
April 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29118728/mutual-influence-of-reward-anticipation-and-emotion-on-brain-activity-during-memory-retrieval
#3
Chunping Yan, Fang Liu, Yunyun Li, Qin Zhang, Lixia Cui
Previous studies on the joint effect of reward motivation and emotion on memory retrieval have obtained inconsistent results. Furthermore, whether and how any such joint effect might vary over time remains unclear too. Accordingly, using the event-related potential (ERP) measurement of high temporal resolution, our study investigates the cognitive and brain mechanisms of monetary reward and emotion affecting the retrieval processes of episodic memory. Twenty undergraduate and graduate students participated in the research, and our study's behavioral results indicated that reward (relative to no reward) and negative emotion (relative to positive and neutral emotion) significantly improved recognition performance...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29117232/rate-of-acyl-migration-in-lysophosphatidylcholine-lpc-is-dependent-upon-the-nature-of-the-acyl-group-greater-stability-of-sn-2-docosahexaenoyl-lpc-compared-to-the-more-saturated-lpc-species
#4
Dhavamani Sugasini, Papasani V Subbaiah
Several previous studies reported that sn-2 acyl lysophosphatidylcholines (LPCs) undergo rapid isomerization due to acyl migration, especially at physiological pH and temperature. However, these studies have been carried out using mostly sn-2 palmitoyl LPC, whereas the naturally occurring sn-2 LPCs are predominantly unsaturated. In this study, we investigated the acyl migration in four naturally occurring sn-2 acyl LPCs (sn-2 16:0, sn-2 18:1, sn-2 20:4, and sn-2 22:6) stored at various temperatures in aqueous or organic solvents, employing LC/MS to analyze the isomer composition...
2017: PloS One
https://www.readbyqxmd.com/read/29115353/lysophosphatidylcholine-modulates-the-aggregation-of-human-islet-amyloid-polypeptide
#5
Yanting Xing, Emily H Pilkington, Miaoyi Wang, Cameron J Nowell, Aleksandr Kakinen, Yunxiang Sun, Bo Wang, Thomas P Davis, Feng Ding, Pu Chun Ke
Amyloid aggregation of human islet amyloid polypeptide (IAPP) is a hallmark of type 2 diabetes (T2D), a metabolic disease and a global epidemic. Although IAPP is synthesized in pancreatic β-cells, its fibrils and plaques are found in the extracellular space indicating a causative transmembrane process. Numerous biophysical studies have revealed that cell membranes as well as model lipid vesicles promote the aggregation of amyloid-β (associated with Alzheimer's), α-synuclein (associated with Parkinson's) and IAPP, through electrostatic and hydrophobic interactions between the proteins/peptides and lipid membranes...
November 8, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29107661/on-understanding-creative-language-the-late-positive-complex-and-novel-metaphor-comprehension
#6
Karolina Rataj, Anna Przekoracka-Krawczyk, Rob H J van der Lubbe
Novel metaphoric sentences have repeatedly evoked larger N400 amplitudes than literal sentences, while investigations of the late positive complex (LPC) have brought inconsistent results, with reports of both increased and reduced amplitudes. In two experiments, we examined novel metaphor comprehension in Polish, using the same set of literal, novel metaphoric, and anomalous sentences. The first aim of the study was to test whether novel metaphors would evoke larger or smaller late positivity complex (LPC) amplitudes compared to literal and anomalous sentences...
October 28, 2017: Brain Research
https://www.readbyqxmd.com/read/29107570/triatoma-infestans-relies-on-salivary-lysophosphatidylcholine-to-enhance-trypanosoma-cruzi-transmission
#7
Michele Souza Lima, Alan Brito Carneiro, Thaís Souto-Padron, José Jurberg, Mário Alberto Cardoso Silva-Neto, Georgia Correa Atella
Triatoma infestans is a mandatory haematophagous vector of Chagas disease in Brazil. Despite a large number of studies on the anti-haemostatic molecules present in its saliva, the role of its salivary components on parasite transmission is poorly understood. Here, we show that the bioactive lipid molecule, lysophosphatidylcholine (LPC), is present in the salivary gland of T. infestans. We characterized the lipid profiles of each unit of the T. infestans salivary gland. We noticed that LPC is present in the three units of the salivary gland and that the insect feeding state does not influence its proportion...
October 28, 2017: Acta Tropica
https://www.readbyqxmd.com/read/29107000/the-erp-correlates-of-self-knowledge-are-assessments-of-one-s-past-present-and-future-traits-closer-to-semantic-or-episodic-memory
#8
Annick N Tanguay, Lauren Benton, Lorenza Romio, Carolin Sievers, Patrick S R Davidson, Louis Renoult
Self-knowledge concerns one's own preferences and personality. It pertains to the self (similar to episodic memory), yet does not concern events. It is factual (like semantic memory), but also idiosyncratic. For these reasons, it is unclear where self-knowledge might fall on a continuum in relation to semantic and episodic memory. In this study, we aimed to compare the event-related potential (ERP) correlates of self-knowledge to those of semantic and episodic memory, using N400 and Late Positive Component (LPC) as proxies for semantic and episodic processing, respectively...
October 26, 2017: Neuropsychologia
https://www.readbyqxmd.com/read/29103792/foveal-development-in-infants-treated-with-bevacizumab-or-laser-photocoagulation-for-retinopathy-of-prematurity
#9
Ryan N Vogel, Margaret Strampe, Oladipo E Fagbemi, Alexis Visotcky, Sergey Tarima, Joseph Carroll, Deborah M Costakos
PURPOSE: To characterize and quantify early foveal development in preterm infants and to compare this development between eyes treated with intravitreal bevacizumab or laser photocoagulation (LPC) and untreated eyes. DESIGN: Observational case series. PARTICIPANTS: One hundred thirty-one preterm infants undergoing retinopathy of prematurity (ROP) screenings. METHODS: Handheld OCT imaging was performed longitudinally on all patients...
November 2, 2017: Ophthalmology
https://www.readbyqxmd.com/read/29102996/prostatectomy-versus-radiotherapy-for-early-stage-prostate-cancer-prepare-study-protocol-for-a-mixed-methods-study-of-treatment-decision-making-in-men-with-localised-prostate-cancer
#10
Allan Ben Smith, Pascal Mancuso, Mark Sidhom, Karen Wong, Megan Berry, Orlando Rincones, Dion Forstner, Lesley Bokey, Afaf Girgis
BACKGROUND: Men diagnosed with localised prostate cancer (LPC) wanting curative treatment face a highly preference-sensitive choice between prostatectomy and radiotherapy, which offer similar cure rates but different side effects. This study aims to determine the information, decision-making needs and preferences of men with LPC choosing between robotic prostatectomy and standard external beam or stereotactic radiotherapy. METHODS AND ANALYSIS: This study will be conducted at a large public teaching hospital in Australia offering the choice between robotic prostatectomy and radiotherapy from early 2017...
November 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/29098269/neural-indices-of-semantic-processing-in-early-childhood-distinguish-eventual-stuttering-persistence-and-recovery
#11
Kathryn Kreidler, Amanda Hampton Wray, Evan Usler, Christine Weber
Purpose: Maturation of neural processes for language may lag in some children who stutter (CWS), and event-related potentials (ERPs) distinguish CWS who have recovered from those who have persisted. The current study explores whether ERPs indexing semantic processing may distinguish children who will eventually persist in stuttering (CWS-ePersisted) from those who will recover from stuttering (CWS-eRecovered). Method: Fifty-six 5-year-old children with normal receptive language listened to naturally spoken sentences in a story context...
November 9, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/29098203/prospective-analysis-of-lipid-composition-changes-with-antiretroviral-therapy-and-immune-activation-in-persons-living-with-hiv
#12
Martha A Belury, Emily Bowman, Janelle Gabriel, Brandon Snyder, Manjusha Kulkarni, Marilly Palettas, Xiaokui Mo, Jordan E Lake, David Zidar, Scott F Sieg, Benigno Rodriguez, Martin P Playford, Adriana Andrade, Daniel R Kuritzkes, Nehal N Mehta, Michael M Lederman, Nicholas T Funderburg
Background: Lipid profiles are altered by HIV infection and antiretroviral therapy (ART). Among HIV-uninfected (HIV-) populations the concentrations of various lipid classes (ie, lyso-phosphatidylcholine, LPC) and their saturated (SaFA), mono-unsaturated (MUFA), and polyunsaturated fatty acid (PUFA) composition are related to cardiometabolic disease risk. Associations between changes in the lipidome and immune activation in HIV-infected (HIV+) individuals beginning ART have not been described...
2017: Pathogens & Immunity
https://www.readbyqxmd.com/read/29080807/safety-evaluation-of-howaru-%C3%A2-restore-lactobacillus-acidophilus-ncfm-lactobacillus-paracasei-lpc-37-bifidobacterium-animalis-subsp-lactis-bl-04-and-b-lactis-bi-07-for-antibiotic-resistance-genomic-risk-factors-and-acute-toxicity
#13
Wesley Morovic, Jason M Roper, Amy B Smith, Pushkor Mukerji, Buffy Stahl, Jessica Caverly Rae, Arthur C Ouwehand
Although probiotic lactobacilli and bifidobacteria are generally considered safe by various regulatory agencies, safety properties, such as absence of transferable antibiotic resistance, must still be determined for each strain prior to market introduction as a probiotic. Safety requirements for probiotics vary regionally and evaluation methods are not standardized, therefore methodologies are often adopted from food ingredients or chemicals to assess microbial safety. Four individual probiotic strains, Lactobacillus acidophilus NCFM(®), Lactobacillus paracasei Lpc-37(®), Bifidobacterium animalis subsp...
November 1, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29079451/2-ome-lysophosphatidylcholine-analogues-are-gpr119-ligands-and-activate-insulin-secretion-from-%C3%AE-tc-3-pancreatic-cells-evaluation-of-structure-dependent-biological-activity
#14
Anna Drzazga, Agata Sowińska, Agnieszka Krzemińska, Andrzej Okruszek, Piotr Paneth, Maria Koziołkiewicz, Edyta Gendaszewska-Darmach
GPR119 receptor has been proposed as a metabolic regulator playing a pivotal role in the modulation of glucose homeostasis in type 2 diabetes. GPR119 was identified on pancreatic β cells and its ligands have the ability to enhance glucose-stimulated insulin secretion (GSIS). Lysophosphatidylcholine (LPC) was shown to potentiate GSIS and our present studies indicate that 2-methoxy-lysophosphatidylcholine (2-OMe-LPC) analogues, unable to undergo 1→2 acyl migration, stimulate GSIS from murine βTC-3 pancreatic cells even more efficiently...
October 24, 2017: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29070040/care-of-the-dialysis-patient-primary-provider-involvement-and-resource-utilization-patterns-a-cohort-study
#15
Bjorg Thorsteinsdottir, Priya Ramar, LaTonya J Hickson, Megan S Reinalda, Robert C Albright, Jon C Tilburt, Amy W Williams, Paul Y Takahashi, Molly M Jeffery, Nilay D Shah
BACKGROUND: Efficient and safe delivery of care to dialysis patients is essential. Concerns have been raised regarding the ability of accountable care organizations to adequately serve this high-risk population. Little is known about primary care involvement in the care of dialysis patients. This study sought to describe the extent of primary care provider (PCP) involvement in the care of hemodialysis patients and the outcomes associated with that involvement. METHODS: In a retrospective cohort study, patients accessing a Midwestern dialysis network from 2001 to 2010 linked to United States Renal Database System and with >90 days follow up were identified (n = 2985)...
October 25, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/29068088/mechanisms-of-lysophosphatidylcholine-induced-demyelination-a-primary-lipid-disrupting-myelinopathy
#16
Jason R Plemel, Nathan J Michaels, Nina Weishaupt, Andrew V Caprariello, Michael B Keough, James A Rogers, Aran Yukseloglu, Jaehyun Lim, Vikas V Patel, Khalil S Rawji, Samuel K Jensen, Wulin Teo, Belinda Heyne, Shawn N Whitehead, Peter K Stys, V Wee Yong
For decades lysophosphatidylcholine (LPC, lysolecithin) has been used to induce demyelination, without a clear understanding of its mechanisms. LPC is an endogenous lysophospholipid so it may cause demyelination in certain diseases. We investigated whether known receptor systems, inflammation or nonspecific lipid disruption mediates LPC-demyelination in mice. We found that LPC nonspecifically disrupted myelin lipids. LPC integrated into cellular membranes and rapidly induced cell membrane permeability; in mice, LPC injury was phenocopied by other lipid disrupting agents...
October 25, 2017: Glia
https://www.readbyqxmd.com/read/29066962/self-referential-information-alleviates-retrieval-inhibition-of-directed-forgetting-effects-an-erp-evidence-of-source-memory
#17
Xinrui Mao, Yujuan Wang, Yanhong Wu, Chunyan Guo
Directed forgetting (DF) assists in preventing outdated information from interfering with cognitive processing. Previous studies pointed that self-referential items alleviated DF effects due to the elaboration of encoding processes. However, the retrieval mechanism of this phenomenon remains unknown. Based on the dual-process framework of recognition, the retrieval of self-referential information was involved in familiarity and recollection. Using source memory tasks combined with event-related potential (ERP) recording, our research investigated the retrieval processes of alleviative DF effects elicited by self-referential information...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/29059709/microglial-dysfunction-as-a-key-pathological-change-in-adrenomyeloneuropathy
#18
Yi Gong, Nikhil Sasidharan, Fiza Laheji, Matthew Frosch, Patricia Musolino, Rudy Tanzi, Doo Yeon Kim, Alessandra Biffi, Joseph El Khoury, Florian Eichler
OBJECTIVE: Mutations in ABCD1 cause the neurodegenerative disease, adrenoleukodystrophy, which manifests as the spinal cord axonopathy adrenomyeloneuropathy (AMN) in nearly all males surviving into adulthood. Microglial dysfunction has long been implicated in pathogenesis of brain disease, but its role in the spinal cord is unclear. METHODS: We assessed spinal cord microglia in humans and mice with AMN and investigated the role of ABCD1 in microglial activity toward neuronal phagocytosis in cell culture...
October 23, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/29052842/shear-stress-upregulates-regeneration-related-immediate-early-genes-in-liver-progenitors-in-3d-ecm-like-microenvironments
#19
Kenichiro Nishii, Erik Brodin, Taylor Renshaw, Rachael Weesner, Emma Moran, Shay Soker, Jessica L Sparks
The role of fluid stresses in activating the hepatic stem/progenitor cell regenerative response is not well understood. This study hypothesized that immediate early genes (IEGs) with known links to liver regeneration will be upregulated in liver progenitor cells (LPCs) exposed to in vitro shear stresses on the order of those produced from elevated interstitial flow after partial hepatectomy. The objectives were: (1) to develop a shear flow chamber for application of fluid stress to LPCs in 3D culture; and (2) to determine the effects of fluid stress on IEG expression in LPCs...
October 20, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/29052073/laparoscopy-for-primary-cytoreduction-with-multivisceral-resections-in-advanced-ovarian-cancer-prospective-validation-the-times-they-are-a-changin
#20
Marcello Ceccaroni, Giovanni Roviglione, Francesco Bruni, Roberto Clarizia, Giacomo Ruffo, Matteo Salgarello, Michele Peiretti, Stefano Uccella
BACKGROUND: Primary cytoreduction is the mainstay of treatment for advanced ovarian cancer (AOC). We developed and prospectively evaluated an algorithm to investigate the possible role of laparoscopic primary cytoreduction (LPC) in carefully selected patients, with AOC. METHODS: From June 2007 to July 2015, all patients with stage III-IV ovarian cancer and clinical conditions allowing aggressive surgery were candidate to primary cytoreduction with the aim of achieving residual tumor (RT) = 0...
October 19, 2017: Surgical Endoscopy
keyword
keyword
31490
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"