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Lauras law

Martie L Skinner, Kevin P Haggerty, Mary Casey-Goldstein, Ronald W Thompson, Laura Buddenberg, W Alex Mason
OBJECTIVES: The changes in Washington State and Colorado marijuana laws call for the development of new brief family-focused adolescent marijuana use preventive interventions that are relevant for and tailored to the context of legalization for retail sale. To that end, focus groups with parents and teens were conducted to find out about their concerns and needs in the context of legalization. METHODS: Six semi-structured focus groups (3 with parents, 3 with teens) were conducted in Washington State in 2013 related to consequences of teen marijuana use and messages that would be effective in helping to prevent teens from using marijuana in the context of legal adult use...
October 21, 2016: Substance Use & Misuse
Erika Franklin Fowler, Laura Baum, Colleen Barry, Jeff Niederdeppe, Sarah E Gollust
Public opinion about the Affordable Care Act (ACA) has been polarized since the law's passage. Past research suggests these conditions would make any media influence on the public limited at best. However, during the early phase of implementation, locally broadcast ACA-related media messages-in the form of paid health insurance and political advertisements and news media stories-abounded as advocates, insurance marketers, and politicians sought to shape the public's perceptions of the law. To what extent did message exposure affect ACA perceptions during the first open enrollment period? We merge data on volumes of messaging at the media market level with nationally representative survey data to examine the relationship between estimated exposure to media messaging and the public's perceptions of how informed they were about and favorable toward the ACA in October 2013...
October 11, 2016: Journal of Health Politics, Policy and Law
Tabassum Firoz, Marianne Vidler, Prestige Tatenda Makanga, Helena Boene, Rogério Chiaú, Esperança Sevene, Laura A Magee, Peter von Dadelszen, Khátia Munguambe
BACKGROUND: Mozambique has one of the highest rates of maternal mortality in sub-Saharan Africa. The main influences on maternal health encompass social, economic, political, environmental and cultural determinants of health. To effectively address maternal mortality in the post-2015 agenda, interventions need to consider the determinants of health so that their delivery is not limited to the health sector. The objective of this exploratory qualitative study was to identify key community groups' perspectives on the perceived determinants of maternal health in rural areas of southern Mozambique...
September 30, 2016: Reproductive Health
Wenya Linda Bi, Peleg Horowtiz, Noah Greenwald, Malak Abedalthagafi, Pankaj K Agarwalla, William J Gibson, Yu Mei, Steven E Schumacher, Uri Ben-David, Aaron Chevalier, Scott L Carter, Grace Tiao, Priscilla K Brastianos, Azra H Ligon, Matthew Ducar, Laura E MacConaill, Edward R Laws, Sandro Santagata, Rameen Beroukhim, Ian F Dunn
PURPOSE: Pituitary adenomas are the second most common primary brain tumor, yet their genetic profiles are incompletely understood. EXPERIMENTAL DESIGN: We performed whole-exome sequencing of 42 pituitary macroadenomas and matched normal DNA. These adenomas included hormonally active and inactive tumors, ones with typical or atypical histology, and ones that were primary or recurrent. RESULTS: We identified mutations, insertions/deletions, and copy number alterations...
October 5, 2016: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
Gita M Ramdharry, Alexander J Pollard, Robert Grant, Elizabeth L Dewar, Matilde Laurá, Sarah A Moore, Kate Hallsworth, Thomas Ploetz, Michael I Trenell, Mary M Reilly
PURPOSE: Charcot Marie Tooth disease (CMT) describes a group of hereditary neuropathies that present with distal weakness, wasting and sensory loss. Small studies indicate that people with CMT have reduced daily activity levels. This raises concerns as physical inactivity increases the risk of a range of co- morbidities, an important consideration in the long-term management of this disease. This study aimed to compare physical activity, patterns of sedentary behavior and overall energy expenditure of people with CMT and healthy matched controls...
August 16, 2016: Disability and Rehabilitation
Nurul Nadia H W Luntungan, M Justin Byron, Melbourne F Hovell, Laura J Rosen, Annisa Anggraeni, Vaughan W Rees
Secondhand smoke exposure (SHS) causes a disproportionate health burden for children, yet existing smoke-free laws are often poorly enforced. We monitored air quality while observing children and adult nonsmokers present in public venues during Ramadan, a period of Muslim religious observance marked by family and social gatherings, in Jakarta, Indonesia. A repeated-measures design was used to assess indoor air quality during and after Ramadan in 43 restaurants and in five smoke-free control venues. Fine particulate matter of 2...
2016: International Journal of Environmental Research and Public Health
Hrishikesh Chakraborty, Robert Neal Axon, Jordan Brittingham, Genevieve Ray Lyons, Laura Cole, Christine B Turley
OBJECTIVE: To evaluate differences in hospital readmission risk across all payers in South Carolina (SC). DATA SOURCES/STUDY SETTING: South Carolina Revenue and Fiscal Affairs Office (SCRFA) statewide all payer claims database including 2,476,431 hospitalizations in SC acute care hospitals between 2008 and 2014. STUDY DESIGN: We compared the odds of unplanned all-cause 30-day readmission for private insurance, Medicare, Medicaid, uninsured, and other payers and examined interaction effects between payer and index admission characteristics using generalized estimating equations...
September 28, 2016: Health Services Research
David Levy, David B Abrams, Jeffrey Levy, Laura Rosen
BACKGROUND: The World Health Organization Framework Convention for Tobacco Control (FCTC) established the MPOWER policy package to provide practical country-level guidance on implementing effective policies to reduce smoking rates. The Abridged SimSmoke tobacco control policy simulation model is applied to Israel to estimate the effects on reducing smoking-attributable mortality resulting from full implementation of MPOWER policies. METHODS: Smoking prevalence from the 2014 Israel National Health Interview Survey 3 and population data from the Israel Central Bureau of Statistics were used to calculate the number of current smokers...
2016: Israel Journal of Health Policy Research
Angela Aherrera, Asli Çarkoğlu, Mutlu Hayran, Gül Ergör, Toker Ergüder, Bekir Kaplan, Jolie Susan, Laura Zheng, Joanna E Cohen, Ana Navas-Acien
INTRODUCTION: In 2009, Turkey extended the smoke-free legislation to hospitality venues. Compliance, however, remains low in some hospitality venues. We identified characteristics associated with knowledge of health effects that can be prevented by the smoke-free law, the attitude towards and enforcement of the law. METHODS: In 2014, we conducted 400 interviews with hospitality venue owners and employees in 7 cities in Turkey. The venues were identified based on a random sampling strategy in a previous phase of the study...
September 19, 2016: Tobacco Control
Lisa C Carlesso, Neil Segal, Jeffrey R Curtis, Barton L Wise, Laura Frey Law, Michael Nevitt, Tuhina Neogi
OBJECTIVES: To examine the longitudinal relation of knee pain, radiographic osteoarthritis (ROA), symptomatic knee OA (SxOA) and knee pain severity to incident widespread pain (WSP). METHODS: The Multicenter Osteoarthritis Study is a longitudinal cohort of persons with or at risk of knee OA. Participants were characterized with regards to consistent frequent knee pain (CFKP), ROA (Kellgren & Lawrence grade ≥2), SxOA, and knee pain severity at the 60-month visit (baseline)...
September 16, 2016: Arthritis Care & Research
Paul E Nevin, Laura Blanar, Annie Phare Kirk, Amy Freedheim, Robert Kaufman, Laura Hitchcock, Jennifer D Maeser, Beth E Ebel
BACKGROUND: In response to the rise of distracted driving, many countries and most US states have adopted laws to restrict the use of handheld phones for drivers. Specific provisions of each law and the overall social mores of distracted driving influence enforceability and impact. OBJECTIVES: Identify multilevel interdependent factors that influence distracted driving enforcement through the perspective of police officers. DESIGN/METHODS: We conducted focus group discussions with active duty law enforcement officers from three large Washington State counties...
September 15, 2016: Injury Prevention: Journal of the International Society for Child and Adolescent Injury Prevention
Mary S Mouw, Jennifer Counts, Corinne Fordham, Molly Merrill Francis, Laura E Bach, Suzanne Maman, Scott K Proescholdbell
BACKGROUND: Injury and violence-related morbidity and mortality present a major public health problem in North Carolina. However, the extent to which local health departments (LHDs) engage in injury and violence prevention (IVP) has not been well described. OBJECTIVES: One objective of the current study is to provide a baseline assessment of IVP in the state's LHDs, describing capacity, priorities, challenges, and the degree to which programs are data-driven and evidence-based...
September 2016: North Carolina Medical Journal
Laura Florence Harris, Jodi Halpern, Ndola Prata, Wendy Chavkin, Caitlin Gerdts
Conscientious objection to abortion - a clinician's refusal to perform abortions because of moral or religious beliefs - is a limited right, intended to protect clinicians' convictions while maintaining abortion access. This paper argues that conscientious objection policies and debates around the world generally do not take into account the social, political, and economic pressures that profoundly influence clinicians who must decide whether to claim objector status. Lack of clarity about abortion policies, high workload, low pay, and stigma towards abortion providers can discourage abortion provision...
September 12, 2016: Global Public Health
David T Felson, Jingbo Niu, Emily K Quinn, Tuhina Neogi, Cara Lewis, Cora E Lewis, Laura Frey Law, Chuck McCulloch, Michael Nevitt, Michael LaValley
OBJECTIVE: Many persons with knee pain have joint pain outside the knee but despite the impact and high frequency of this pain, its distribution and causes have not been studied. Those studying gait abnormalities have suggested that knee pain causes pain in adjacent joints but pain adaptation strategies are highly individualized. METHODS: We studied persons age 50-79 years with or at high risk of knee osteoarthritis drawn from two community-based cohorts, the Multicenter Osteoarthritis Study and the Osteoarthritis Initiative and followed for 5-7 years...
September 2, 2016: Arthritis & Rheumatology
Constance Crawford, Laura Reynolds
No abstract text is available yet for this article.
September 2016: Pharmaceutical Patent Analyst
Laura Lester Rothfeldt, Naveen Patil, Dirk T Haselow, Sandy Hainline Williams, J Gary Wheeler, Leonard N Mukasa
During early September 2014, the Arkansas Department of Health identified an increased number of tuberculosis (TB) cases among a unique population in a well-circumscribed geographical area in northwest Arkansas. The Compact of Free Association Act of 1985 (Public Law 99-239, amended in 2003 by Public Law 108-188) established the Republic of the Marshall Islands (RMI) as an independent nation, and persons from the RMI can travel freely (with valid RMI passport) to and from the United States as nonimmigrants without visas (1)...
2016: MMWR. Morbidity and Mortality Weekly Report
Paul K Potter, Michael R Bowl, Prashanthini Jeyarajan, Laura Wisby, Andrew Blease, Michelle E Goldsworthy, Michelle M Simon, Simon Greenaway, Vincent Michel, Alun Barnard, Carlos Aguilar, Thomas Agnew, Gareth Banks, Andrew Blake, Lauren Chessum, Joanne Dorning, Sara Falcone, Laurence Goosey, Shelley Harris, Andy Haynes, Ines Heise, Rosie Hillier, Tertius Hough, Angela Hoslin, Marie Hutchison, Ruairidh King, Saumya Kumar, Heena V Lad, Gemma Law, Robert E MacLaren, Susan Morse, Thomas Nicol, Andrew Parker, Karen Pickford, Siddharth Sethi, Becky Starbuck, Femke Stelma, Michael Cheeseman, Sally H Cross, Russell G Foster, Ian J Jackson, Stuart N Peirson, Rajesh V Thakker, Tonia Vincent, Cheryl Scudamore, Sara Wells, Aziz El-Amraoui, Christine Petit, Abraham Acevedo-Arozena, Patrick M Nolan, Roger Cox, Anne-Marie Mallon, Steve D M Brown
Determining the genetic bases of age-related disease remains a major challenge requiring a spectrum of approaches from human and clinical genetics to the utilization of model organism studies. Here we report a large-scale genetic screen in mice employing a phenotype-driven discovery platform to identify mutations resulting in age-related disease, both late-onset and progressive. We have utilized N-ethyl-N-nitrosourea mutagenesis to generate pedigrees of mutagenized mice that were subject to recurrent screens for mutant phenotypes as the mice aged...
2016: Nature Communications
Scott Burris, Laura Hitchcock, Jennifer Ibrahim, Matthew Penn, Tara Ramanathan
Governments use statutes, regulations, and policies, often in innovative ways, to promote health and safety. Organizations outside government, from private schools to major corporations, create rules on matters as diverse as tobacco use and paid sick leave. Very little of this activity is systematically tracked. Even as the rest of the health system is working to build, share, and use a wide range of health and social data, legal information largely remains trapped in text files and pdfs, excluded from the universe of usable data...
August 16, 2016: Journal of Health Politics, Policy and Law
Laura Cox, V Tamara Montrose
Quantity discrimination is a basic form of numerical competence where an animal distinguishes which of two amounts is greater in size. Whilst quantity discrimination in rats has been investigated via training paradigms, rats' natural quantity discrimination abilities without explicit training for a desired response have not been explored. This study investigated domestic rats' ability to perform quantity discrimination. Domestic rats ( n = 12) were examined for their ability to distinguish the larger amount under nine quantity comparisons...
2016: Animals: An Open Access Journal From MDPI
Iska Moxon-Emre, Michael D Taylor, Eric Bouffet, Kristina Hardy, Cynthia J Campen, David Malkin, Cynthia Hawkins, Normand Laperriere, Vijay Ramaswamy, Ute Bartels, Nadia Scantlebury, Laura Janzen, Nicole Law, Karin S Walsh, Donald J Mabbott
PURPOSE: To evaluate intellectual functioning and the implications of limiting radiation exposure in the four biologically distinct subgroups of medulloblastoma: wingless (WNT), sonic hedgehog (SHH), Group 3, and Group 4. PATIENTS AND METHODS: A total of 121 patients with medulloblastoma (n = 51, Group 4; n = 25, Group 3; n = 28, SHH; and n = 17, WNT), who were treated between 1991 and 2013 at the Hospital for Sick Children (Toronto, Ontario, Canada), Children's National Health System (Washington, DC), or the Lucile Packard Children's Hospital (Palo Alto, CA), had intellectual assessments...
August 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
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