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https://www.readbyqxmd.com/read/28640937/dreams-and-creative-problem-solving
#1
Deirdre Barrett
Dreams have produced art, music, novels, films, mathematical proofs, designs for architecture, telescopes, and computers. Dreaming is essentially our brain thinking in another neurophysiologic state-and therefore it is likely to solve some problems on which our waking minds have become stuck. This neurophysiologic state is characterized by high activity in brain areas associated with imagery, so problems requiring vivid visualization are also more likely to get help from dreaming. This article reviews great historical dreams and modern laboratory research to suggest how dreams can aid creativity and problem-solving...
June 22, 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/28635483/student-life-imposter-syndrome
#2
Mandy Day-Calder
I will never forget the first time I stepped onto a ward as a nursing student in my freshly ironed new uniform. Everything was going well. This was it, I was living my dream. And then an older woman called out for a nurse, looked at me, and I froze. I wasn't a 'real' nurse, so what on earth was I to do?
June 21, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28632218/the-stuff-of-dreams
#3
Tanya Lewis
No abstract text is available yet for this article.
June 20, 2017: Scientific American
https://www.readbyqxmd.com/read/28628967/post-bionian-developments-in-psychoanalytic-field-theory-the-contributions-of-antonino-ferro-and-giuseppe-civitarese
#4
S Montana Katz
The Bi-Personal Field: Experiences in Child Psychoanalysis. By Antonino Ferro. New York: Routledge, 1992 (1999). 232 pp. The Intimate Room: Theory and Technique of the Analytic Field. By Giuseppe Civitarese. New York: Routledge, 2008 (2010). 240 pp. The Necessary Dream: New Theories and Techniques of Interpretation in Psychoanalysis. By Giuseppe Civitarese; translated by Ian Harvey. London: Karnac, 2013 (2014). 246 pp. The Analytic Field and Its Transformations. By Antonino Ferro and Giuseppe Civitarese. London: Karnac, 2015...
April 2017: Psychoanalytic Quarterly
https://www.readbyqxmd.com/read/28628957/affect-symptom-fantasy-dream-clinical-and-theoretical-considerations
#5
Eugene J Mahon
A symptom being studied in the process of analysis can be seen as not unlike the unconscious affect it sprang from. The author presents a case in which a symptom, premature ejaculation, was analogous to the unconscious affect of guilt, which itself seemed to be a premature defensive transformation of a deeper current of anger. Guilt was interpreted as if it were a psychic premature ejaculation, a defensive derailment of anger. Fantasy and dream seemed to be engaged in similar transformations, with a fantasy of "premature incarceration" not unlike the symptom itself in its analogous functioning...
April 2017: Psychoanalytic Quarterly
https://www.readbyqxmd.com/read/28628226/the-future-of-dream-science
#6
Kelly Bulkeley
This article describes the future prospects of scientific dream research. Three frontiers of investigation hold special promise: neuroscientific studies of the brain-mind system's activities during sleep (such as during lucid dreaming); systematic analyses of large collections of dream reports from diverse populations of people; and psychotherapeutic explorations of the multiple dimensions of personal and collective meaning woven into the dream experiences of each individual. Several helpful books on the science of sleep and dreaming are mentioned for further study...
June 19, 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/28627884/hdx-ms-reveals-calcium-binding-properties-and-allosteric-regulation-of-downstream-regulatory-element-antagonist-modulator-dream
#7
Jun Zhang, Jing Li, Theodore A Craig, Rajiv Kumar, Michael L Gross
Downstream regulatory element antagonist modulator (DREAM) is an EF-hand Ca2+-binding protein that also binds to specific DNA sequence, downstream regulatory elements (DRE), and thereby regulates transcription in a calcium-dependent fashion. DREAM binds to DRE in the absence of Ca2+, but detaches from DRE under Ca2+ stimulation, allowing gene expression. The Ca2+-binding properties of DREAM and the consequences of the binding on protein structure are key to understanding the function of DREAM. Here we describe the application of hydrogen deuterium exchange mass spectrometry (HDX-MS) and site-directed mutagenesis to investigate the Ca2+ binding properties and the subsequent conformational changes of full length DREAM...
June 19, 2017: Biochemistry
https://www.readbyqxmd.com/read/28627327/paolo-mantegazza-and-the-dream-of-making-science-popular-circa-1860-1900
#8
Cristiano Turbil
No abstract text is available yet for this article.
July 2017: Public Understanding of Science
https://www.readbyqxmd.com/read/28625125/dreams-and-psychedelics-neurophenomenological-comparison-and-therapeutic-implications
#9
Rainer Kraehenmann
A resurgence of neurobiological and clinical research is currently underway into the therapeutic potential of serotonergic or 'classical' psychedelics, such as the prototypical psychedelic drug lysergic acid diethylamide (LSD), psilocybin (4-phosphoryloxy-N,N-dimethyltryptamine), and ayahuasca - a betacarboline- and dimethyltryptamine (DMT)-containing Amazonian beverage. However, the mechanisms of therapeutic action are still not fully explained. Given that an altered state of consciousness is a common denominator that characterizes all classical psychedelics and given that both rapid eye movement sleep (REMS) and psychedelics modulate perception, mental imagery, emotion activation, fear memory extinction, and sense of self and body, in the present article, these two states of consciousness are systematically compared, and therapeutically relevant conclusions are drawn based on available evidence...
June 18, 2017: Current Neuropharmacology
https://www.readbyqxmd.com/read/28620339/the-stress-acceleration-hypothesis-of-nightmares
#10
Tore Nielsen
Adverse childhood experiences can deleteriously affect future physical and mental health, increasing risk for many illnesses, including psychiatric problems, sleep disorders, and, according to the present hypothesis, idiopathic nightmares. Much like post-traumatic nightmares, which are triggered by trauma and lead to recurrent emotional dreaming about the trauma, idiopathic nightmares are hypothesized to originate in early adverse experiences that lead in later life to the expression of early memories and emotions in dream content...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28618458/dreaming-a-gateway-to-the-unconscious
#11
Steve Paulson, Deirdre Barrett, Kelly Bulkeley, Rubin Naiman
Where do our dreams originate from, and what do they tell us? Is there a universal set of symbols that are common to all dreams, regardless of a person's ethnicity or culture? What does dreaming reveal about the unconscious? Why do some dreams remain etched in our memories, whereas others are almost instantly forgotten? Some scientists have adopted the position that dreams are little more than noise in the brain, without any substantive purpose or function. Yet, such a stance seemingly runs counter to the experience of many people who reflect upon and even analyze their dreams, often in search of clues to their daily lives or insights into their deeper selves...
June 15, 2017: Annals of the New York Academy of Sciences
https://www.readbyqxmd.com/read/28614298/erf-mutations-reveal-a-balance-of-ets-factors-controlling-prostate-oncogenesis
#12
Rohit Bose, Wouter R Karthaus, Joshua Armenia, Wassim Abida, Phillip J Iaquinta, Zeda Zhang, John Wongvipat, Elizabeth V Wasmuth, Neel Shah, Patrick S Sullivan, Michael G Doran, Ping Wang, Anna Patruno, Yilin Zhao, Deyou Zheng, Nikolaus Schultz, Charles L Sawyers
Half of all prostate cancers are caused by the TMPRSS2-ERG gene-fusion, which enables androgens to drive expression of the normally silent E26 transformation-specific (ETS) transcription factor ERG in prostate cells. Recent genomic landscape studies of such cancers have reported recurrent point mutations and focal deletions of another ETS member, the ETS2 repressor factor ERF. Here we show these ERF mutations cause decreased protein stability and mostly occur in tumours without ERG upregulation. ERF loss recapitulates the morphological and phenotypic features of ERG gain in normal mouse prostate cells, including expansion of the androgen receptor transcriptional repertoire, and ERF has tumour suppressor activity in the same genetic background of Pten loss that yields oncogenic activity by ERG...
June 14, 2017: Nature
https://www.readbyqxmd.com/read/28612755/learning-to-see-again-biological-constraints-on-cortical-plasticity-and-the-implications-for-sight-restoration-technologies
#13
Michael Beyeler, Ariel Rokem, Geoffrey Boynton, Ione Fine
The "bionic eye" - so long a dream of the future - is finally becoming a reality with retinal prostheses available to patients in both the US and Europe. However, clinical experience with these implants has made it apparent that the vision provided by these devices differs substantially from normal sight. Consequently, the ability to learn to make use of this abnormal retinal input plays a critical role in whether or not some functional vision is successfully regained. The goal of the present review is to summarize the vast basic science literature on developmental and adult cortical plasticity with an emphasis on how this literature might relate to the field of prosthetic vision...
June 14, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28606067/through-the-client-s-eyes-using-narratives-to-explore-experiences-of-care-transfers-during-pregnancy-childbirth-and-the-neonatal-period
#14
Cherelle M V van Stenus, Mark Gotink, Magda M Boere-Boonekamp, Anneke Sools, Ariana Need
BACKGROUND: The client experience is an important outcome in the evaluation and development of perinatal healthcare. But because clients meet different professionals, measuring such experiences poses a challenge. This is especially the case in the Netherlands, where pregnant women are often transferred between professionals due to the nation's approach to risk selection. This paper explores questions around how clients experience transfers of care during pregnancy, childbirth, and the neonatal period, as well as how these experiences compare to the established quality of care aspects the Dutch Patient Federation developed...
June 12, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28595539/targeted-drug-delivery-systems-and-its-therapeutic-applications-in-cancer-and-related-immune-pathological-conditions
#15
Saifullah Afridi, Jamshed Iqbal, Fareeha Anwar
BACKGROUND: Earlier a century ago, Paul Ehrlich proposed an idea of a drug "magic bullet" that selectively eradicate diseased cells without harming the surrounding normal cells. OBJECTIVE: Since a lot of progress has been attained in this field to discover new horizons for targeted delivery of drug. As major problem in disease therapy is the severe toxic effects of prescribed drugs on healthy cells. In order to reduce the adverse effects of chemotherapy on healthy tissues, herein, we summaries the use of recent drug delivery systems for targeted therapy...
June 5, 2017: Infectious Disorders Drug Targets
https://www.readbyqxmd.com/read/28593531/distinguishing-appraisal-and-personality-influences-on-quality-of-life-in-chronic-illness-introducing-the-quality-of-life-appraisal-profile-version-2
#16
Bruce D Rapkin, Iliana Garcia, Wesley Michael, Jie Zhang, Carolyn E Schwartz
BACKGROUND: Cognitive appraisal of quality of life (QOL) differs across individuals in ways that explain otherwise paradoxical findings, such as similar QOL ratings among individuals in highly divergent health states. Although warranted by a growing body of evidence, routine assessment of appraisal in QOL research has been impeded by measurement challenges. This study describes the QOL Appraisal Profile-version 2 (QOLAPv2), a new measure that addresses these challenges. METHODS: A heterogeneous, on-line cohort of chronic disease patients and caregivers completed the QOLAPv2, along with demographics, PROMIS10 and Brief NEO Personality Inventory (NEO-PI)...
June 7, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28590203/manifest-dream-content-as-a-predictor-of-suicidality
#17
Myron L Glucksman, Milton Kramer
A number of behavioral, social, biological, and cultural factors are associated with suicide. However, the ability to predict an imminent suicide attempt remains problematic. Prior studies indicate that the manifest dream content of depressed, non-suicidal patients differs from that of depressed, suicidal patients. The dream imagery of depressed, suicidal patients contains themes of death, dying, violence, and departure. The dream imagery of depressed, non-suicidal patients contains themes of rejection, helplessness, hopelessness, humiliation, failure, and loss...
2017: Psychodynamic Psychiatry
https://www.readbyqxmd.com/read/28585737/a-new-measure-of-hallucinatory-states-and-a-discussion-of-rem-sleep-dreaming-as-a-virtual-laboratory-for-the-rehearsal-of-embodied-cognition
#18
Clemens Speth, Jana Speth
Hallucinatory states are experienced not only in connection with drugs and psychopathologies but occur naturally and spontaneously across the human circadian cycle: Our nightly dreams bring multimodal experiences in the absence of adequate external stimuli. The current study proposes a new, tighter measure of these hallucinatory states: Sleep onset, REM sleep, and non-REM sleep are shown to differ with regard to (a) motor imagery indicating interactions with a rich imaginative world, and (b) cognitive agency that could enable sleepers to recognize their hallucinatory state...
June 6, 2017: Cognitive Science
https://www.readbyqxmd.com/read/28580341/targeting-innate-immunity-to-downmodulate-adaptive-immunity-and-reverse-type-1-diabetes
#19
REVIEW
Arata Itoh, William M Ridgway
Type 1 diabetes (T1D) is characterized by specific destruction of pancreatic insulin-producing beta cells accompanied by evidence of beta-cell-directed autoimmunity such as autoreactive T cells and islet autoantibodies (IAAs). Currently, T1D cannot be prevented or reversed in humans. T1D is easy to prevent in the nonobese diabetic (NOD) spontaneous mouse model but reversing new-onset T1D in mice is more difficult. Since the discovery of the T-cell receptor in the 1980s and the subsequent identification of autoreactive T cells directed toward beta-cell antigens (eg, insulin, glutamic acid decarboxylase), the dream of antigen-specific immunotherapy has dominated the field with its promise of specificity and limited side effects...
2017: ImmunoTargets and Therapy
https://www.readbyqxmd.com/read/28575720/local-aspects-of-sleep-and-wakefulness
#20
REVIEW
Francesca Siclari, Giulio Tononi
Slow waves, the hallmark of NREM (Non Rapid Eye Movement) sleep, are not uniformly distributed across the cortical surface, but can occur locally and asynchronously across brain regions. Their regional distribution and amplitude is affected by brain maturation and by time spent awake, mediated in part by experience-dependent changes in synaptic strength. Recent studies have shown that local low-frequency oscillations (<10Hz) can also occur in REM sleep and during wakefulness, leading to region-specific cognitive errors...
May 30, 2017: Current Opinion in Neurobiology
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