keyword
https://read.qxmd.com/read/38529436/penile-calciphylaxis-a-successfully-treated-case
#21
Narine Misakyan, Amer Abu-Shanab, Shazia Shah
Penile calciphylaxis is a rare presentation of calcific uremic arteriolopathy and can be a life-threatening condition usually seen in patients with end-stage renal failure with hemodialysis. The clear etiopathogenesis of calciphylaxis is not fully understood, but it is postulated to be characterized by the accumulation of calcium in the microvessels of adipose tissue and skin, which leads to ischemia and necrosis, causing painful ulcerations, and could potentially be complicated by sepsis and mortality...
February 2024: Curēus
https://read.qxmd.com/read/38529404/plantar-pressure-gradient-and-pressure-gradient-angle-are-affected-by-inner-pressure-of-air-insole
#22
JOURNAL ARTICLE
Fahni Haris, Yih-Kuen Jan, Ben-Yi Liau, Chang-Wei Hsieh, Wei-Cheng Shen, Chien-Cheng Tai, Yin-Hwa Shih, Chi-Wen Lung
Clinically, air insoles may be applied to shoes to decrease plantar pressure gradient (PPG) and increase plantar gradient angle (PGA) to reduce foot ulcers. PPG and PGA may cause skin breakdown. The effects of different inner pressures of inflatable air insoles on dynamic PPG and PGA distributions are largely unknown in non-diabetics and people with diabetes. This study aimed to explore the impact of varying inner air insole pressures on PPG and PGA to establish early mitigation strategies for people at risk of foot ulcers...
2024: Frontiers in Bioengineering and Biotechnology
https://read.qxmd.com/read/38528847/hyperbaric-oxygen-therapy-for-diabetic-foot-ulcers-based-on-wagner-grading-a-systematic-review-and-meta-analysis
#23
JOURNAL ARTICLE
Mendy Hatibie Oley, Maximillian Christian Oley, Billy Johnson Kepel, Muhammad Faruk, Angelica Maurene Joicetine Wagiu, Irawan Sukarno, Marcella Tirsa Tulong, Vania Sukarno
BACKGROUND: Diabetic foot ulcers (DFUs) are common complications of uncontrolled diabetes mellitus that can result in infection and amputation of the lower extremities. This study compared the benefits and risks of hyperbaric oxygen therapy with those of other DFU treatments, based on the Wagner grading system. METHODS: Systematic searches for randomly controlled trials using hyperbaric oxygen therapy for DFUs were performed using PubMed, the Cochrane Library, and Embase...
March 2024: Plastic and Reconstructive Surgery. Global Open
https://read.qxmd.com/read/38528197/calcium-polystyrene-sulfonate-induced-rectal-ulcer-causing-e-coli-native-valve-infective-endocarditis
#24
JOURNAL ARTICLE
Shinnosuke Fukushima, Hideharu Hagiya, Hiroyuki Honda, Tomoharu Ishida, Ryohei Shoji, Kou Hasegawa, Fumio Otsuka
Escherichia coli-associated native-valve infective endocarditis is a rare disease that affects elderly patients with underlying risk factors such as diabetes mellitus, malignancy, and renal failure. Long-term use of calcium polystyrene sulfonate is a potential risk factor for gastrointestinal mucosal damage or even colorectal ulcers. Herein, we describe a fatal case of a 66-year-old Japanese man with diabetes mellitus and renal failure who was prescribed calcium polystyrene sulfonate (CPS) for 11 years and developed a CPS-induced rectal ulcer, leading to E...
March 25, 2024: Clinical Journal of Gastroenterology
https://read.qxmd.com/read/38528132/prevalence-of-diabetic-kidney-disease-and-the-associated-factors-among-patients-with-type-2-diabetes-in-a-multi-ethnic-asian-country
#25
JOURNAL ARTICLE
Kim Sui Wan, Noran Naqiah Hairi, Feisul Mustapha, Muhammad Fadhli Mohd Yusoff, Halizah Mat Rifin, Mastura Ismail, Foong Ming Moy, Noor Ani Ahmad
The actual prevalence of diabetic kidney disease (DKD) in patients with type 2 diabetes (T2D) in Malaysia is unknown. We aimed to determine the prevalence of DKD and its associated risk factors among T2D patients in Malaysia. An analytical cross-sectional study was conducted using the year 2022 clinical audit dataset from the National Diabetes Registry. DKD was defined as albuminuria, a decreased glomerular filtration rate, or both. Among 80,360 patients, 62.2% were female, 68.4% were Malay, and the mean age was 61...
March 25, 2024: Scientific Reports
https://read.qxmd.com/read/38528003/integrated-image-and-location-analysis-for-wound-classification-a-deep-learning-approach
#26
JOURNAL ARTICLE
Yash Patel, Tirth Shah, Mrinal Kanti Dhar, Taiyu Zhang, Jeffrey Niezgoda, Sandeep Gopalakrishnan, Zeyun Yu
The global burden of acute and chronic wounds presents a compelling case for enhancing wound classification methods, a vital step in diagnosing and determining optimal treatments. Recognizing this need, we introduce an innovative multi-modal network based on a deep convolutional neural network for categorizing wounds into four categories: diabetic, pressure, surgical, and venous ulcers. Our multi-modal network uses wound images and their corresponding body locations for more precise classification. A unique aspect of our methodology is incorporating a body map system that facilitates accurate wound location tagging, improving upon traditional wound image classification techniques...
March 25, 2024: Scientific Reports
https://read.qxmd.com/read/38527332/impact-of-synthetic-extracellular-matrices-in-combination-therapy-with-amniotic-allografting-in-the-treatment-of-diabetic-foot-wounds-a-case-series
#27
JOURNAL ARTICLE
Arthur Evensen, Jodi Walters, James Dancho, Valarie Samoy, David Jolley
Synthetic extracellular matrices are artificial polymers that are elongated and deposited as a matrix of nanofibers which mimic the native extracellular matrix. RenovoDerm® Anthem™ Wound Matrix (Columbus, Ohio) is comprised of polyglycolic acid and poly (L-lactide-co-caprolactone) which degrade by hydrolysis into a-hydroxy and fatty acids, lowering the pH and promoting regenerative cellular activity including angiogenesis. Amniotic allografts contain growth factors, cytokines, amino acids, extracellular matrix proteins, and hyaluronic acid which are recognized as intrinsic to the wound healing process...
March 22, 2024: Surgical Technology International
https://read.qxmd.com/read/38525394/the-effectiveness-of-neurodynamic-techniques-in-patients-with-diabetic-peripheral-neuropathy-study-protocol-for-a-randomized-sham-controlled-trial
#28
JOURNAL ARTICLE
Mahdi Ashoori, Mohammadreza Pourahmadi, Seyed Ebrahim Hashemi, Mehdi Dadgoo, Mahboobeh Sadat Hosseini
BACKGROUND: Diabetic peripheral neuropathy (DPN) is one of the most common complications of diabetes mellitus (DM). DPN is the primary risk factor for diabetic foot ulcers that can cause amputation. Although several observational studies have investigated the morphological and biomechanical characteristics of peripheral nerves in DPN, interventional studies regarding the effectiveness of neurodynamic techniques (NDT) in DPN patients are confined to a handful. The effects of NDT on neuropathy severity, nerve conduction parameters, quality of life (QoL), and mechanosensitivity have not been explored yet in this population...
2024: Advanced Biomedical Research
https://read.qxmd.com/read/38524772/cost-effectiveness-analysis-for-commonly-used-human-cell-and-tissue-products-in-the-management-of-diabetic-foot-ulcers
#29
JOURNAL ARTICLE
Leo M Nherera, Jaideep Banerjee
BACKGROUND AND AIMS: This study considers the cost-effectiveness of commonly used cellular, acellular, and matrix‑like products (CAMPs) of human origin also known as human cell and tissue products (HCT/Ps) in the management of diabetic foot ulcers. METHODS: We developed a 1-year economic model assessing six CAMPs [cryopreserved placental membrane with viable cells (vCPM), bioengineered bilayered living cellular construct (BLCC), human fibroblast dermal substitute (hFDS), dehydrated human amnion chorion membrane (dHACM), hypothermically stored amniotic membrane (HSAM) and human amnion membrane allograft (HAMA) which had randomized controlled trial evidence compared with standard of care (SoC)...
March 2024: Health Science Reports
https://read.qxmd.com/read/38524127/cd64-plays-a-key-role-in-diabetic-wound-healing
#30
JOURNAL ARTICLE
Xiuqin Zhang, Liuhong Yuan, Zhenyu Tan, Huiyan Wu, Feier Chen, Junjie Huang, Pengjun Wang, Brett D Hambly, Shisan Bao, Kun Tao
INTRODUCTION: Wound healing poses a clinical challenge in diabetes mellitus (DM) due to compromised host immunity. CD64, an IgG-binding Fcgr1 receptor, acts as a pro-inflammatory mediator. While its presence has been identified in various inflammatory diseases, its specific role in wound healing, especially in DM, remains unclear. OBJECTIVES: We aimed to investigate the involvement of CD64 in diabetic wound healing using a DM animal model with CD64 KO mice. METHODS: First, we compared CD64 expression in chronic skin ulcers from human DM and non-DM skin...
2024: Frontiers in Immunology
https://read.qxmd.com/read/38523326/an-eye-for-a-foot-alarming-unawareness-of-diabetic-retinopathy-among-diabetic-foot-patients
#31
JOURNAL ARTICLE
Hikmet Erhan Güven, Eyüpcan Sensoy, Mehmet Citirik
This study aims to determine the awareness of diabetic retinopathy in patients hospitalized for diabetic foot ulcers, examine their clinical and demographic characteristics, and evaluate their treatment needs. In this prospective study, 62 consequent patients with diabetic foot ulcers who were hospitalized for further treatment in Diabetic Foot Department between June and August 2023 were subjected to ophthalmological examinations. Detailed anterior and posterior segment examinations were performed. Clinical and demographic characteristics and HbA1c levels were recorded...
March 24, 2024: International Journal of Lower Extremity Wounds
https://read.qxmd.com/read/38522472/topical-oxygen-therapy-and-singlet-oxygen-in-wound-healing-a-scoping-review
#32
REVIEW
Martina Sýkorová, Christine Joy Moffatt, Neil Stentiford, Ewa Anna Burian, Sasagaki Katsuhiro, Yang Wei
The aim of this scoping review was to provide an overview of current research into topical oxygen therapies including the under-researched singlet oxygen for wound healing. A scoping review was undertaken using five databases. After duplicates and ineligible studies were excluded, 49 studies were included for a narrative review. Out of the included 49 studies, 45 (91.8%) were published in the past 10 years (2013-2023) with 32 (65.3%) published in the past 5 years (2018-2023). Eight of the studies were systematic reviews and/or meta-analysis and 18 were RCTs...
April 2024: International Wound Journal
https://read.qxmd.com/read/38522433/the-impact-of-inflammatory-biomarkers-on-amputation-rates-in-patients-with-diabetic-foot-ulcers
#33
JOURNAL ARTICLE
Yun Xu, Ruina Geng, Xiangyu Meng, Zhipeng Feng, Xu Wang, Guanying Zhang, Liwei Bai
Diabetic Foot Ulcers (DFUs) are a major complication of diabetes, often leading to amputation. Understanding the relationship between haematological inflammatory markers and the incidence of amputation in DFU patients with infectious complications is crucial for improving management and outcomes. This retrospective study, conducted from May 2020 to October 2022, involved 109 patients with DFUs, categorised into amputation (AM) and non-amputation (NAM) groups. Patients were evaluated for various factors, including demographic data, DFU duration, and blood parameters such as haemoglobin A1c (HbA1c), haemoglobin (Hb), albumin (ALB), white blood cell count (WBC), erythrocyte sedimentation rate (ESR), procalcitonin (PCT), C-reactive protein (CRP), platelet-to-lymphocyte ratio (PLR), neutrophil-to-lymphocyte ratio (NLR), and lymphocyte-to-monocyte ratio (LMR)...
April 2024: International Wound Journal
https://read.qxmd.com/read/38520602/the-why-what-and-where-podcast-on-the-updated-2023-iwgdf-guideline-on-offloading-treatments-for-diabetes-related-foot-ulcers
#34
JOURNAL ARTICLE
Sicco A Bus, Peter A Lazzarini
In this podcast the lead authors of the 2023 International Working Group on the Diabetic Foot (IWGDF) guideline on offloading treatments for diabetes-related foot ulcers briefly discuss why we need offloading treatments for people with diabetes-related foot ulcers, what the new international offloading guideline recommends, and where offloading treatment might go into the future.A podcast audio is available with this article.
March 23, 2024: Diabetes Therapy: Research, Treatment and Education of Diabetes and related Disorders
https://read.qxmd.com/read/38518039/the-effect-of-hyperbaric-oxygen-therapy-on-hematological-indices-and-biochemical-parameters-in-patients-with-diabetic-foot
#35
JOURNAL ARTICLE
Erdinç Ercan, Gamze Aydin, Bülent Erdoğan, Fatih Özçelik
BACKGROUND: Diabetes Mellitus (DM) is a metabolic disease with a high morbidity and mortality and increasing in prevalence all over the world. Due to the hypoxic, ischemic, inflammatory, and infective environment in DM, diabetic foot ulcers have been treated with medico-surgical interventions and adjuvant hyperbaric oxygen Therapy (HBOT). The purpose of this study was to evaluate the effects of HBOT on hematological indices and biochemical parameters in patients with diabetic foot. METHODS: The study group was formed from the file records of 103 male patients who applied to Yunus Emre State Hospital HBOT Center between September 1, 2016 and December 31, 2020, and were treated HBOT with a multidisciplinary approach...
March 22, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38515381/innovate-therapeutic-targets-for-autoimmune-diseases-insights-from-proteome-wide-mendelian-randomization-and-bayesian-colocalization
#36
JOURNAL ARTICLE
Qiubai Jin, Feihong Ren, Ping Song
BACKGROUND: Despite growing knowledge regarding the pathogenesis of autoimmune diseases (ADs) onset, the current treatment remains unsatisfactory. This study aimed to identify innovative therapeutic targets for ADs through various analytical approaches. RESEARCH DESIGN AND METHODS: Utilizing Mendelian randomization, Bayesian co-localization, phenotype scanning, and protein-protein interaction network, we explored potential therapeutic targets for 14 ADs and externally validated our preliminary findings...
December 2024: Autoimmunity
https://read.qxmd.com/read/38515182/economic-burden-of-diabetic-foot-ulcer-a-case-of-iran
#37
JOURNAL ARTICLE
Reza Hashempour, SeyedHadi MirHashemi, Fariba Mollajafari, Soheila Damiri, Ali ArabAhmadi, Behzad Raei
BACKGROUND: Diabetic foot ulcer (DFU) is known as a serious complication of diabetes mellitus in patients with diabetes, imposing heavy medical costs on healthcare systems due to its chronic nature. patients with severe diabetic foot ulcer are often disabled to work, and some of them may even die, leading to associated productivity losses. Since no previous study has investigated the economic burden of DFU in Iran, this study is to estimate the economic burden of diabetic foot disease in Iran...
March 21, 2024: BMC Health Services Research
https://read.qxmd.com/read/38513698/out-of-pocket-expenditure-among-patients-with-diabetic-foot-ulcer-in-a-tertiary-care-hospital-of-south-india-a-cross-sectional-study
#38
JOURNAL ARTICLE
Hariharan Seshadri, Venkatesh Karthikeyan, Malavika Rudrakumar, Prashanth Seshadri, Damodaran Vasudevan, Vasuki Ranganathan, Tirth Dave, Victor Ghosh, Vadada Ramsai, Balakrishnan Kamaraj
Diabetic foot ulcer is a debilitating complication of long-standing diabetes mellitus. Patients lose their earning potential, face repeated hospitalizations, and are forced to bear heavy treatment costs. This places an enormous financial burden on the patients and their families. This study seeks to ascertain the out-of-pocket expenditure among these patients and correlate it with their risk factor profile. In this hospital-based cross-sectional study, a total of 154 patients with diabetic foot ulcers or amputations have been studied with an elaborate patient questionnaire and relevant clinical examinations...
April 2024: International Wound Journal
https://read.qxmd.com/read/38511527/objective-evidence-that-nerve-decompression-surgery-reduces-neuropathic-dfu-recurrence-risk-to-less-than-5
#39
JOURNAL ARTICLE
Scott Nickerson, Dwayne S Yamasaki
SCOPE AND SIGNIFICANCE Care for the diabetic foot ulcer (DFU) continues to be a frustrating challenge. Standard of care (SOC) methods are plagued by regrettable levels of delayed healing, failures to heal, recurrence risk, and association with amputations and early mortality.1 We hope to bring attention to the clinical reports observing that diabetes is frequently accompanied by nerve trunk enlargement. Local sites of compression can then occur that cause neural dysfunction and pain, but respond to surgical nerve decompression (ND) and recover a degree of normal function...
March 21, 2024: Advances in Wound Care
https://read.qxmd.com/read/38510515/plantar-kinetics-during-wheeled-knee-walker-use-compared-to-different-assistive-walking-devices-in-persons-with-type-2-diabetes-mellitus
#40
JOURNAL ARTICLE
Holton C Gwaltney, Joseph W Harrington, Jose G Anguiano-Hernandez, David C Kingston
BACKGROUND: Diabetic patients with foot ulcers are commonly prescribed assistive walking devices to unload the affected foot and promote tissue healing. However, the effect on shear loads to the contralateral foot is unknown. This study investigated the effect of a wheeled knee walker (WKW), compared to common devices, on compressive and shear plantar forces carried by the propulsive foot during walking in patients with type 2 diabetes mellitus. A secondary objective investigated plantar forces' correlations with body weight unloaded (BWU)...
January 2024: Foot & ankle orthopaedics
keyword
keyword
31464
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.