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https://www.readbyqxmd.com/read/28306169/economic-burden-of-relapsed-or-refractory-multiple-myeloma-results-from-an-international-trial
#1
Don Robinson, Robert Z Orlowski, Michael Stokes, Jianming He, Samuel Huse, Abhishek Chitnis, Britte Kranenburg, Annette Lam
OBJECTIVE: The direct cost of relapsed or refractory multiple myeloma (RRMM) is documented; indirect costs are being explored. Healthcare payers seek cost offsets from therapies that improve clinical outcomes but challenge budgets; employers seek lower absenteeism and better productivity. Study goals were to: 1) Identify direct and indirect economic factors of RRMM and, 2) Explore longitudinal relationships between clinical, economic, and health-related quality of life (HRQoL) assessments...
March 17, 2017: European Journal of Haematology
https://www.readbyqxmd.com/read/28302638/innovative-approach-for-self-management-and-social-welfare-of-children-with-cystic-fibrosis-in-europe-development-validation-and-implementation-of-an-mhealth-tool-mycyfapp
#2
Joaquim Calvo-Lerma, Celia P Martinez-Jimenez, Juan-Pablo Lázaro-Ramos, Ana Andrés, Paula Crespo-Escobar, Erlend Stav, Cornelia Schauber, Lucia Pannese, Jessie M Hulst, Lucrecia Suárez, Carla Colombo, Celeste Barreto, Kris de Boeck, Carmen Ribes-Koninckx
INTRODUCTION: For the optimal management of children with cystic fibrosis, there are currently no efficient tools for the precise adjustment of pancreatic enzyme replacement therapy, either for advice on appropriate dietary intake or for achieving an optimal nutrition status. Therefore, we aim to develop a mobile application that ensures a successful nutritional therapy in children with cystic fibrosis. METHODS AND ANALYSIS: A multidisciplinary team of 12 partners coordinate their efforts in 9 work packages that cover the entire so-called 'from laboratory to market' approach by means of an original and innovative co-design process...
March 16, 2017: BMJ Open
https://www.readbyqxmd.com/read/28284287/-even-the-best-law-will-never-replace-reflection-in-the-field
#3
Jean-Pierre Bouchard
Implemented in 2006 by the French minister for health, the resource centres for people working with sex offenders (CRIAVS) provide support for professionals and non-professionals, concerned with transgressive sexual behaviour. They offer tools for legal, health and social professionals to facilitate the supervision of sex offenders. Florent Cochez, a psychiatrist and medical examiner, manager of the Aquitaine CRIAVS, describes in this interview the missions of these regional structures, their link with court-ordered therapy and his practice...
March 2017: Soins. Psychiatrie
https://www.readbyqxmd.com/read/28278589/assessment-and-treatment-of-mental-fatigue-after-a-traumatic-brain-injury
#4
Birgitta Johansson, Lars Rönnbäck
Mental fatigue is a frequently occurring symptom after mild, moderate or severe traumatic brain injury (TBI). Such mental fatigue may become a long-lasting problem, irrespective of severity and even after recovery from other neurological or psychiatric symptoms. Two characteristics of this mental fatigue are that patients easily become exhausted and there is generally a long recovery time. There is a need to increase knowledge and awareness of mental fatigue as it interferes considerably with work, studies, and social activities...
March 1, 2017: Neuropsychological Rehabilitation
https://www.readbyqxmd.com/read/28278061/transphobia-among-students-majoring-in-the-helping-professions
#5
Gila M Acker
The study was designed to further the understanding of transphobia among students majoring in the helping professions including social work, occupational therapy, and nursing. The study's hypotheses examined the effects of transgender content in education (e.g., textbooks and lectures), religiosity, contact with transgender people, and several sociodemographic variables with transphobia. Differences in transphobia levels between social work students and those in aligned professions were also explored. The sample consisted of 600 students of a public, urban university in New York City who participated in an online survey...
February 10, 2017: Journal of Homosexuality
https://www.readbyqxmd.com/read/28276958/disease-activity-in-and-quality-of-life-of-patients-with-psoriatic-arthritis-mutilans-the-nordic-pam-study
#6
U Lindqvist, B Gudbjornsson, L Iversen, L Laasonen, L Ejstrup, T Ternowitz, M Ståhle
OBJECTIVE: To describe the social status and health-related quality of life of patients with psoriatic arthritis mutilans (PAM) in the Nordic countries. METHOD: Patients with at least one mutilated joint confirmed by radiology were studied. Disease activity involving joints and skin, physician-assessed disease activity, and patient's education and work status were recorded. Data from the 36-item Short Form Health Survey, Health Assessment Questionnaire and Dermatology Life Quality Index questionnaire were gathered and correlated with disease duration, pain, and general well-being (visual analogue scale)...
February 10, 2017: Scandinavian Journal of Rheumatology
https://www.readbyqxmd.com/read/28274788/management-goals-for-type-1-gaucher-disease-an-expert-consensus-document-from-the-european-working-group-on-gaucher-disease
#7
M Biegstraaten, T M Cox, N Belmatoug, M G Berger, T Collin-Histed, S Vom Dahl, M Di Rocco, C Fraga, F Giona, P Giraldo, M Hasanhodzic, D A Hughes, P O Iversen, A I Kiewiet, E Lukina, M Machaczka, T Marinakis, E Mengel, G M Pastores, U Plöckinger, H Rosenbaum, C Serratrice, A Symeonidis, J Szer, J Timmerman, A Tylki-Szymańska, M Weisz Hubshman, D I Zafeiriou, A Zimran, C E M Hollak
Gaucher Disease type 1 (GD1) is a lysosomal disorder that affects many systems. Therapy improves the principal manifestations of the condition and, as a consequence, many patients show a modified phenotype which reflects manifestations of their disease that are refractory to treatment. More generally, it is increasingly recognised that information as to how a patient feels and functions [obtained by patient- reported outcome measurements (PROMs)] is critical to any comprehensive evaluation of treatment. A new set of management goals for GD1 in which both trends are reflected is needed...
October 24, 2016: Blood Cells, Molecules & Diseases
https://www.readbyqxmd.com/read/28267811/patient-education-for-people-with-multiple-sclerosis-associated-fatigue-a-systematic-review
#8
Maria Janina Wendebourg, Christoph Heesen, Marcia Finlayson, Björn Meyer, Jana Pöttgen, Sascha Köpke
BACKGROUND: Multiple Sclerosis (MS) is an inflammatory and neurodegenerative disease often causing decreased quality of life, social withdrawal and unemployment. Studies examining the effect of pharmacological interventions demonstrated only minor effects, whereas non-pharmacological interventions as e.g. patient education programs have shown promising results. OBJECTIVE: We aim to systematically review the literature to determine the effect of patient education programs on fatigue in MS...
2017: PloS One
https://www.readbyqxmd.com/read/28258685/-analysis-of-phonosurgical-methods-of-treatment-in-spasmodic-dysphonia
#9
Bożena Kosztyła-Hojna, Greta Berger, Maciej Zdrojkowski
Spasmodic dysphonia (SD) is rather a rare voice disorder. It is most often seen in woman aged 40-50. The disease is caused by deep emotional and neurological disorders of extrapyramidal system. Two main clinical forms of SD are distinguished: about 90% of cases - adductor spasmodic dysphonia and abductor spasmodic dysphonia roughly 10%. Conservative therapy does not always yield sufficient effects. Botulinum toxin - type A injections into the thyroarytenoid muscle are also used in therapy. Though results are temporary and reversible...
February 20, 2017: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28256931/barriers-to-discharge-from-inpatient-rehabilitation-a-teamwork-approach
#10
Lisanne Catherine Cruz, Jeffrey S Fine, Subhadra Nori
Purpose In order to prevent adverse events during the discharge process, coordinating appropriate community resources, medication reconciliation, and patient education needs to be implemented before the patient leaves the hospital. This coordination requires communication and effective teamwork amongst staff members. In order to address these concerns, the purpose of this paper is to incorporate the TeamSTEPPS principles to develop a discharge plan that would best meet the needs of the patients as they return to the community...
March 13, 2017: International Journal of Health Care Quality Assurance
https://www.readbyqxmd.com/read/28253214/attitudes-toward-adoption-of-evidence-based-practice-among-physical-therapists-and-social-workers-a-lesson-for-interprofessional-continuing-education
#11
Bjorg Gudjonsdottir, Hervor A Arnadottir, Halldor S Gudmundsson, Sigrun Juliusdottir, Solveig A Arnadottir
INTRODUCTION: Professionals who embrace evidence-based practice (EBP) continually search for research evidence, appraise, and apply it, while interacting with each client in his/her situation. This dynamic learning process takes a substantial commitment from professionals and requires a positive attitude toward EBP. The main objective of this research was to explore the following: 1) distinct dimensions of attitudes toward adoption of EBP among physical therapists and social workers and 2) the relationship between these dimensions of attitudes and selected background characteristics of the compared professions...
January 2017: Journal of Continuing Education in the Health Professions
https://www.readbyqxmd.com/read/28252323/insulin-knowledge-and-practice-a-survey-of-district-nurses-in-northern-ireland
#12
Alison Robb, Bernie Reid, Elizabeth A Laird
Insulin is one of the top ten high-alert medications worldwide. Approximately 30% of people with diabetes in the UK use injectable therapies, most commonly insulin, to manage their condition. With an increasing number of people with diabetes being managed within the community, district nurses play an important role in the safe and effective use of insulin. This study surveyed a convenience sample of 164 district nurses working within one Health and Social Care Trust in Northern Ireland to ascertain their knowledge and practice regarding insulin...
March 2, 2017: British Journal of Community Nursing
https://www.readbyqxmd.com/read/28251350/variables-associated-with-patient-reported-outcomes-in-persons-with-chronic-myeloid-leukemia-receiving-tyrosine-kinase-inhibitor-therapy
#13
Qian Jiang, Hai-Bo Wang, Lu Yu, Robert Peter Gale
PURPOSE: Explore patient-reported outcomes (PROs), including health-related quality of life (HRQoL), satisfaction with therapy, impact of the therapy on work and daily life, and concerns related to the therapy and identify variables associated with PROs in persons with chronic myeloid leukemia (CML) receiving tyrosine kinase inhibitors (TKIs). METHODS: Across-sectional questionnaire was distributed to adults with chronic phase CML and answered anonymously. SF-36 Health Survey was used to measure HRQoL...
March 1, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28250915/the-reset-mindset-model-applied-on-decreasing-antibiotic-usage-in-dairy-cattle-in-the-netherlands
#14
REVIEW
T J G M Lam, J Jansen, R J Wessels
BACKGROUND: Prudent use of antibiotics is important to prevent antibiotic resistance in humans and in animals. For this reason politicians demanded a decrease of total antibiotic use and of use of critically important antibiotics in animal husbandry in the Netherlands. In the dairy sector the use of antibiotics almost halved in the years 2009-2015, with a decrease of the use of critically important antibiotics to very low levels. THEORY OF BEHAVIOUR CHANGE: To realize a sustainable decrease in antibiotic usage, the mindset towards the subject was considered crucial...
2017: Irish Veterinary Journal
https://www.readbyqxmd.com/read/28236511/do-patient-characteristics-moderate-the-effect-of-extended-release-naltrexone-xr-ntx-for-opioid-use-disorder
#15
Peter D Friedmann, Donna Wilson, Edward V Nunes, Randall Hoskinson, Joshua D Lee, Michael Gordon, Sean M Murphy, Richard J Bonnie, Donna T Chen, Tamara Y Boney, Charles P O'Brien
BACKGROUND: Extended release naltrexone (XR-NTX) injected intramuscularly monthly has been shown to reduce relapse in persons with opioid use disorder. Baseline factors, including patients' demographics, comorbidities and lifestyle, may help identify patients who will benefit most or least from XR-NTX treatment. METHODS: Potential moderators of XR-NTX's effect were examined in the largest North American randomized open-label effectiveness trial of XR-NTX. Relapse status (Yes/No) at 6-month follow-up was regressed on treatment group (XR-NTX, N=153; or Treatment-as-Usual [TAU], N=155), baseline covariates, and their two-way interaction to identify moderator effects...
February 21, 2017: Journal of Substance Abuse Treatment
https://www.readbyqxmd.com/read/28236265/the-longitudinal-course-of-depression-symptomatology-following-a-palliative-rehabilitation-program
#16
Andrea Feldstain, Sophie Lebel, Martin R Chasen
PURPOSE: Patients with advanced cancer have increased life expectancy but suffer from ongoing burden. Depressive symptomatology is their most common mental health concern. The Ottawa Palliative Rehabilitation Program (PRP) offers rehabilitation for this population. It offers 8 weeks of individualized interdisciplinary rehabilitation, post cancer treatment. Interventions include medical (physician and nurse), physiotherapy, occupational therapy, dietary, and social work using a general self-efficacy framework...
February 24, 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28229917/factors-related-to-self-directed-learning-readiness-of-students-in-health-professional-programs-a-scoping-review
#17
REVIEW
Craig E Slater, Anne Cusick
BACKGROUND: Academic and professional drivers have stimulated interest in self-directed learning of students in pre-certification health professional programs. Particular attention has focussed on factors which may influence a students' readiness for self-directed learning. METHOD: A five stage structured scoping review of published literature was conducted to identify measures of self-directed learning readiness used with students in pre-certification health professional programs and those factors that have been investigated as potential determinants...
February 14, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/28229290/the-patients-perspective-living-with-lupus-in-austria
#18
Georg Stummvoll, Tanja Stamm
Systemic lupus erythematosus (SLE) is a heterogeneous disease with a vast variety of clinical manifestations. Timely diagnosis is important for gaining access to specific therapy and care. In this survey, we asked SLE patients with an established diagnosis to report about their personal history and their daily life with SLE in order to gain knowledge about diagnostics, treatment pathways and potential problems in daily living and functioning. In most cases, the diagnosis of SLE was made by a specialist in rheumatology or dermatology...
February 22, 2017: Wiener Klinische Wochenschrift
https://www.readbyqxmd.com/read/28228103/disease-manifestations-and-burden-of-illness-in-patients-with-acid-sphingomyelinase-deficiency-asmd
#19
REVIEW
Margaret M McGovern, Ruzan Avetisyan, Bernd-Jan Sanson, Olivier Lidove
Acid sphingomyelinase deficiency (ASMD), a rare lysosomal storage disease, is an autosomal recessive genetic disorder caused by different SMPD1 mutations. Historically, ASMD has been classified as Niemann-Pick disease (NPD) types A (NPD A) and B (NPD B). NPD A is associated with a uniformly devastating disease course, with rapidly progressing psychomotor degeneration, leading to death typically by the age of 3 years, most often from respiratory failure. In contrast, the clinical phenotype and life expectancy of patients with NPD B may vary widely...
February 23, 2017: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/28221059/emotion-focused-therapy-for-social-anxiety-disorder-results-from-a-multiple-baseline-study
#20
Ben Shahar, Eran Bar-Kalifa, Eve Alon
OBJECTIVE: The purpose of the present study was to evaluate the efficacy of emotion-focused therapy (EFT) for adults suffering from social anxiety disorder (SAD). METHOD: Using a nonconcurrent multiple-baseline design, 12 patients (mean age = 26.75 years, SD = 5.15; 7 males) meeting criteria for SAD were treated with up to 28 sessions of EFT. EFT was based on an empathic relationship, 2-chair work for self-criticism, empty-chair work for unresolved feelings, and focusing...
March 2017: Journal of Consulting and Clinical Psychology
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