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https://www.readbyqxmd.com/read/28706386/alarming-emergence-molecular-characterization-and-outcome-of-blandm-1-in-patients-infected-with-multidrug-resistant-gram-negative-bacilli-in-a-tertiary-care-hospital
#1
Huma Naim, Meher Rizvi, Mohd Azam, Richa Gupta, Neelam Taneja, Indu Shukla, Haris M Khan
INTRODUCTION: This study was conducted to assess the prevalence of metallo-beta-lactamases (MBLs) in general and blaNDM-1 in particular. It also aimed at evaluating clinical characteristics and outcome in patients infected with MBLs. MATERIALS AND METHODS: A total of 116 carbapenem-resistant Gram-negative bacilli (CRGNB) were evaluated in the study. These CRGNB were tested for MBL production both phenotypically for MBLs and genotypically for blaNDM-1 gene by polymerase chain reaction (PCR)...
July 2017: Journal of Laboratory Physicians
https://www.readbyqxmd.com/read/28642990/how-health-humanities-will-save-the-life-of-the-humanities
#2
Craig M Klugman
In the last decade, the humanities have been shrinking in number of students, percent of faculty, and in number of degrees awarded. Humanities students also earn lower salaries than their STEM-prepared peers. At the same time, the health humanities have been in ascendance over the last fifteen years. The number of majors, minors and certificates has increased 266% in that time frame, attracting large numbers of students and preparing future patients, lay caregivers, and health care providers to interact with a complicated and dehumanized medical system...
June 23, 2017: Journal of Medical Humanities
https://www.readbyqxmd.com/read/28637294/over-time-impacts-of-pictorial-health-warning-labels-and-their-differences-across-smoker-subgroups-results-from-adult-smokers-in-canada-and-australia
#3
Kamala Swayampakala, James F Thrasher, Hua-Hie Yong, Gera E Nagelhout, Lin Li, Ron Borland, David Hammond, Richard J O'Connor, James W Hardin
Introduction: This study examines patterns of change in different smoker subgroups' responses to new pictorial health warning labels (HWLs) over the initial, two year post-implementation period in Canada, where HWLs include package inserts with cessation messages, and Australia, where "plain" packaging (i.e., prohibition of brand imagery) was also implemented. Methods: Data were collected from online consumer panels in Canada (nsmokers=3,153; nobservations=5,826) and Australia (nsmokers=2,699; nobservations=5,818) from September 2012 to September 2014, with approximately 1,000 adult smokers surveyed in each country every four months, using replenishment to maintain sample size...
June 16, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28610948/adaptive-capacity-an-evolutionary-neuroscience-model-linking-exercise-cognition-and-brain-health
#4
REVIEW
David A Raichlen, Gene E Alexander
The field of cognitive neuroscience was transformed by the discovery that exercise induces neurogenesis in the adult brain, with the potential to improve brain health and stave off the effects of neurodegenerative disease. However, the basic mechanisms underlying exercise-brain connections are not well understood. We use an evolutionary neuroscience approach to develop the adaptive capacity model (ACM), detailing how and why physical activity improves brain function based on an energy-minimizing strategy. Building on studies showing a combined benefit of exercise and cognitive challenge to enhance neuroplasticity, our ACM addresses two fundamental questions: (i) what are the proximate and ultimate mechanisms underlying age-related brain atrophy, and (ii) how do lifestyle changes influence the trajectory of healthy and pathological aging?...
July 2017: Trends in Neurosciences
https://www.readbyqxmd.com/read/28609353/laboratory-animal-bite-anaphylaxis-a-national-survey-part-2-treatment-protocols
#5
Gregg M Stave, Edward H Lee, Dennis J Darcey
OBJECTIVE: This study documents current treatment protocols for laboratory animal bite anaphylaxis in the United States. METHODS: An online survey was e-mailed to designated institutional officials at laboratory animal facilities identified by the National Institutes of Health Office of Laboratory Animal Welfare. RESULTS: One hundred eighty-nine organizations responded to the question of whether they had a treatment protocol with 32% indicating that they had a protocol...
June 12, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28594095/electronic-remote-blood-issue-near-patient-blood-allocation-using-an-automated-blood-storage-system
#6
Sophie Staples, Clare O'Callaghan, Julie Staves, Michael F Murphy
No abstract text is available yet for this article.
June 8, 2017: Transfusion
https://www.readbyqxmd.com/read/28590168/experimental-life-cycle-of-varestrongylus-eleguneniensis-nematoda-protostrongylidae-in-a-captive-reindeer-rangifer-tarandus-tarandus-and-a-muskox-ovibos-moschatus-moschatus
#7
Pratap Kafle, Josh Sullivan, Guilherme G Verocai, Susan J Kutz
The life-cycle of a recently described protostrongylid lungworm, Varestrongylus eleguneniensis, which infects caribou, muskoxen, and moose from Arctic and boreal regions of North America, was completed experimentally for the first time. A native North American slug species, Deroceras laeve was infected with the first-stage larvae (L1), isolated from the feces of wild muskoxen, to generate L3. These were administered to a captive reindeer calf ( 250 L3) and an adult captive muskox (380 L3). The prepatent periods for the reindeer and muskox were 56 and 72 days, respectively...
June 7, 2017: Journal of Parasitology
https://www.readbyqxmd.com/read/28585556/beneficial-effects-of-statins-on-the-rates-of-hepatic-fibrosis-hepatic-decompensation-and-mortality-in-chronic-liver-disease-a-systematic-review-and-meta-analysis
#8
REVIEW
Sehrish Kamal, Muhammad Ali Khan, Ankur Seth, George Cholankeril, Deepansh Gupta, Utkarsh Singh, Faisal Kamal, Colin W Howden, Christopher Stave, Satheesh Nair, Sanjaya K Satapathy, Aijaz Ahmed
OBJECTIVES: Statins may improve outcomes in patients with chronic liver disease (CLD). We conducted a systematic review and meta-analysis to evaluate the impact of statins in the setting of CLD. METHODS: We searched several databases from inception to 17 October 2016 to identify comparative studies evaluating the role of statins in CLD. Outcomes of interest were the associations between statin use and progression of fibrosis, development of hepatic decompensation in cirrhosis, and mortality in CLD...
June 6, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28534026/how-cells-can-control-their-size-by-pumping-ions
#9
Alan R Kay
The ability of all cells to set and regulate their size is a fundamental aspect of cellular physiology. It has been known for sometime but not widely so, that size stability in animal cells is dependent upon the operation of the sodium pump, through the so-called pump-leak mechanism (Tosteson and Hoffman, 1960). Impermeant molecules in cells establish an unstable osmotic condition, the Donnan effect, which is counteracted by the operation of the sodium pump, creating an asymmetry in the distribution of Na(+) and K(+) staving off water inundation...
2017: Frontiers in Cell and Developmental Biology
https://www.readbyqxmd.com/read/28530825/effect-of-wood-aging-on-wine-mineral-composition-and-87-sr-86-sr-isotopic-ratio
#10
Ayse D Kaya, Raúl Bruno de Sousa, António S Curvelo-Garcia, Jorge M Ricardo-da-Silva, Sofia Catarino
The evolution of mineral composition and wine strontium isotopic ratio (87)Sr/(86)Sr (Sr IR) during wood aging were investigated. A red wine was aged in stainless steel tanks with French oak staves (Quercus sessiliflora Salisb.), with three industrial scale replicates. Sampling was carried out after 30, 60, and 90 days of aging, and the wines were evaluated in terms of general analysis, phenolic composition, total polysaccharides, multielement composition, and Sr IR. Li, Be, Mg, Al, Sc, Ti, V, Mn, Co, Ni, Cu, Zn, Ga, Ge, As, Rb, Sr, Y, Zr, Mo, Sb, Cs, Ba, Pr, Nd, Sm, Eu, Dy, Ho, Er, Yb, Lu, Tl, and Pb elements and (87)Sr/(86)Sr were determined by quadrupole inductively coupled plasma mass spectrometry (Q-ICP-MS) and Na, K, Ca, and Fe by flame atomic absorption spectrometry (FAAS)...
June 14, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/28520867/activity-of-ceftolozane-tazobactam-against-surveillance-and-problem-enterobacteriaceae-pseudomonas-aeruginosa-and-non-fermenters-from-the-british-isles
#11
David M Livermore, Shazad Mushtaq, Daniele Meunier, Katie L Hopkins, Robert Hill, Rachael Adkin, Aiysha Chaudhry, Rachel Pike, Peter Staves, Neil Woodford
Background: We assessed the activity of ceftolozane/tazobactam against consecutive isolates collected in the BSAC Bacteraemia Surveillance from 2011 to 2015 and against 'problem' isolates sent to the UK national reference laboratory from July 2015, when routine testing began. Methods: Susceptibility testing was by BSAC agar dilution with resistance mechanisms identified by PCR and interpretive reading. Results: Data were reviewed for 6080 BSAC surveillance isolates and 5473 referred organisms...
May 16, 2017: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/28498340/nutritional-potential-of-selected-insect-species-reared-on-the-island-of-sumatra
#12
Anna Adámková, Jiří Mlček, Lenka Kouřimská, Marie Borkovcová, Tomáš Bušina, Martin Adámek, Martina Bednářová, Jan Krajsa
Inhabitants of the Indonesian island of Sumatra are faced with the problem of insufficient food supplies and the consequent risk of undernourishment and health issues. Edible insects as a traditional and readily available food source could be part of the solution. The nutritional value of insects depends on many factors, e.g., species, developmental stage, sex, diet, and climatic conditions. However, edible insects bred in Sumatra for human consumption have never before been assessed with regard to their nutritional value...
May 12, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28484399/biochemical-benefits-diagnosis-and-clinical-risks-evaluation-of-kratom
#13
REVIEW
Dimy Fluyau, Neelambika Revadigar
BACKGROUND: Kratom (Mitragyna speciosa) is a tropical tree with a long history of traditional use in parts of Africa and Southeast Asia. Kratom is also known as Thom, Thang, and Biak. Its leaves and the teas brewed from them have long been used by people in that region to manage pain and opioid withdrawal and to stave off fatigue. Kratom is actually consumed throughout the world for its stimulant effects and as an opioid substitute (in form of tea, chewed, smoked, or ingested in capsules)...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28479590/cerebral-granulomatous-inflammation-secondary-to-hydrophilic-polymer-embolization-following-thrombectomy
#14
Craig Meiers, Yoftahe Abebe, Neville M Alberto, John Riedinger, Dane A Breker, Michael Manchak, Alexander Drofa, Corey Teigen
BACKGROUND Given the recent completion of multiple trials demonstrating the benefit of endovascular mechanical thrombectomy for select patients with proximal large artery occlusive ischemic strokes, there has been a large increase in the performance of these procedures. In the context of increased thrombectomy performance, there have also been increased reports of rare occurrences of granulomatous inflammatory response to the hydrophilic polymer which coat many of these interventional devices. CASE REPORT A 59-year-old female presented with a complete occlusion of her right proximal middle cerebral artery (MCA) and imaging showed a large area of penumbra...
May 8, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28468468/re-etikk-og-estetikk-ved-prehospital-torakotomi
#15
William Ottestad, Per B Bredmose, Per Olav Berve, Halvard Stave, Gunnar Farstad, Lars Wik, Mårten Sandberg
No abstract text is available yet for this article.
May 2017: Tidsskrift for Den Norske Lægeforening: Tidsskrift for Praktisk Medicin, Ny Række
https://www.readbyqxmd.com/read/28437143/motivations-for-botanical-use-by-socioeconomically-diverse-urban-adults-does-evidence-support-motivation
#16
Grace F Duffy, Emily Stave Shupe, Marie Fanelli Kuczmarski, Alan B Zonderman, Michele K Evans
OBJECTIVE: The study objectives were to characterize botanical dietary supplement (BDS) use and to compare the motivations for botanical supplement (BS) use to the efficacy of the botanical in a socioeconomically and racially diverse urban adult population. METHODS: Subjects were from the Healthy Aging in Neighborhoods of Diversity across the Life Span (HANDLS) study, a 20-year prospective health disparities study with African American and white adults from Baltimore, Maryland...
February 16, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28430678/laboratory-animal-bite-anaphylaxis-a-national-survey-part-1-case-series-and-review-of-the-literature
#17
Gregg M Stave, Edward H Lee, Dennis J Darcey
OBJECTIVE: This study documents previously unreported cases of laboratory animal bite anaphylaxis in animal laboratory facilities in the United States. METHODS: An online survey was e-mailed to designated institutional officials at laboratory animal facilities identified by the National Institutes of Health Office of Laboratory Animal Welfare. RESULTS: One hundred ninety eight organizations responded and 15 organizations indicated that workers had experienced anaphylaxis following an animal bite...
April 20, 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28420434/the-neuroprotective-effects-of-human-bone-marrow-mesenchymal-stem-cells-are-dose-dependent-in-tnbs-colitis
#18
Ainsley M Robinson, Ahmed A Rahman, Sarah Miller, Rhian Stavely, Samy Sakkal, Kulmira Nurgali
BACKGROUND: The incidence of inflammatory bowel diseases (IBD) is increasing worldwide with patients experiencing severe impacts on their quality of life. It is well accepted that intestinal inflammation associates with extensive damage to the enteric nervous system (ENS), which intrinsically innervates the gastrointestinal tract and regulates all gut functions. Hence, treatments targeting the enteric neurons are plausible for alleviating IBD and associated complications. Mesenchymal stem cells (MSCs) are gaining wide recognition as a potential therapy for many diseases due to their immunomodulatory and neuroprotective qualities...
April 18, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28409698/less-is-more-does-the-addition-of-barrel-staves-improve-results-in-endoscopic-strip-craniectomy-for-sagittal-craniosynostosis
#19
MULTICENTER STUDY
Benjamin C Wood, Edward S Ahn, Joanna Y Wang, Albert K Oh, Robert F Keating, Gary F Rogers, Suresh N Magge
OBJECTIVE Endoscopic strip craniectomy (ESC) with postoperative helmet orthosis is a well-established treatment option for sagittal craniosynostosis. There are many technical variations to the surgery ranging from simple strip craniectomy to methods that employ multiple cranial osteotomies. The purpose of this study was to determine whether the addition of lateral barrel-stave osteotomies during ESC improved morphological outcomes. METHODS An IRB-approved retrospective review was conducted on a consecutive series of cases involving ESC for sagittal craniosynostosis at 2 different institutions from March 2008 to August 2014...
July 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28372165/measurements-of-the-effects-of-wine-maceration-with-oak-chips-using-an-electronic-tongue
#20
Alisa Rudnitskaya, Leigh M Schmidtke, Ana Reis, M Rosario M Domingues, Ivonne Delgadillo, Bruno Debus, Dmitry Kirsanov, Andrey Legin
The use of oak products as a cheaper alternative to expensive wood barrels was recently permitted in Europe, which led to a continuous increase in the use of oak chips and staves in winemaking. The feasibility of the potentiometric electronic tongue as a tool for monitoring the effects of wine maceration with oak chips was evaluated. Four types of commercially available oak chips subjected to different thermal treatments and washing procedures and their mixture were studied. Ethanolic extracts of the chips were analysed using electrospray mass spectrometry and 28 phenolic and furanic compounds were identified...
August 15, 2017: Food Chemistry
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