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https://www.readbyqxmd.com/read/27911288/the-effect-of-base-transceiver-station-waves-on-some-immunological-and-hematological-factors-in-exposed-persons
#1
Mohammad Taheri, Ghodratollah Roshanaei, Jamileh Ghaffari, Samira Rahimnejad, Behzad Nazel Khosroshahi, Mohsen Aliabadi, Mohammad Mahdi Eftekharian
BACKGROUND: Since the number of mobile subscribers has significantly increased in recent years, the installation and deployment of Base Transceiver Station (BTS) antennas sending and receiving signals has become common and inevitable in different regions. OBJECTIVE: In this study, we have tried to evaluate the effect of the waves on some immunological and hematological parameters in exposed individuals. In this study, the exposed and non-exposed individuals were used as the test and control groups, respectively...
November 25, 2016: Human Antibodies
https://www.readbyqxmd.com/read/27910760/immunomodulation-effect-of-aqueous-extract-of-the-artist-s-conk-medicinal-mushroom-ganoderma-applanatum-agaricomycetes-on-the-rainbow-trout-oncorhynchus-mykiss
#2
Azadeh Manayi, Mahdi Vazirian, Fereshteh Hassan Zade, Akram Tehranifard
It is well known that innate immunity in fish can be activated by many synthetic and natural immunos-timulants; several natural substances induced immunity in fish in previous surveys. This study discussed data regarding the effect of Ganoderma applanatum aqueous extract on the defense mechanisms of rainbow trout in feeding trials. Fish were fed 250, 500, and 1000 mg extract/kg diet 4 times daily. Growth, humoral parameters, lysozyme activity, and serum protein concentrations were assessed after a period of 45 days...
2016: International Journal of Medicinal Mushrooms
https://www.readbyqxmd.com/read/27904836/pulmonary-complications-of-transcatheter-arterial-chemoembolization-for-hepatocellular-carcinoma
#3
Quan M Nhu, Harry Knowles, Paul J Pockros, Catherine T Frenette
Transarterial chemoembolization (TACE) is an effective palliative intervention that is widely accepted for the management of hepatocellular carcinoma (HCC). Post-TACE pulmonary complications resulting in acute lung injury (ALI) or acute respiratory distress syndrome (ARDS) are rare events. Pulmonary complications after TACE are thought to be related to chemical injury subsequent to the migration of the infused ethiodized oil or chemotherapeutic agent to the lung vasculature, facilitated by arteriovenous (AV) shunts within the hyper-vascular HCC...
2016: World Journal of Respirology
https://www.readbyqxmd.com/read/27897313/the-impact-of-fist-clenching-and-its-maintenance-during-venipuncture-on-routine-hematology-testing
#4
Gabriel Lima-Oliveira, Gian Cesare Guidi, Gian Luca Salvagno, Giuseppe Lippi
BACKGROUND: Prevention of a disturbance of the blood vessel allows phlebotomists to collect a blood specimen by venipuncture that will truly mirror the patient condition. This study was aimed to evaluate the impact of repeated fist clenching and maintenance of the fist during blood collection by venipuncture for routine hematology testing. METHODS: Blood were collected from 16 healthy volunteers with two separate sequential procedures, entailing standard venipuncture with hand opened throughout blood collection, or clenching the fist six times before venipuncture and maintaining the fist until completion of blood collection...
November 29, 2016: Journal of Clinical Laboratory Analysis
https://www.readbyqxmd.com/read/27894962/clinico-pathology-and-hemato-biochemistry-responses-in-buffaloes-infected-with-pasteurella-multocida-type-b-2-immunogen-outer-membrane-protein
#5
Eric Lim Teik Chung, Faez Firdaus Jesse Abdullah, Ali Dhiaa Marza, Wessam Monther Mohammed Saleh, Hayder Hamzah Ibrahim, Yusuf Abba, Mohd Zamri-Saad, Abd Wahid Haron, Abdul Aziz Saharee, Mohd Azmi Mohd Lila, Mohd Jefri Norsidin
The aim of this study was to investigate the clinico-pathology and haemato-biochemistry alterations in buffaloes inoculated with Pasteurella multocida type B:2 immunogen outer membrane protein via subcutaneous and oral routes. Nine buffalo heifers were divided equally into 3 treatment groups. Group 1 was inoculated orally with 10 mL of phosphate buffer saline (PBS); Group 2 and 3 were inoculated with 10 mL of outer membrane protein broth subcutaneously and orally respectively. Group 2 buffaloes showed typical haemorrhagic septicaemia clinical signs and were only able to survive for 72 h of the experiment...
November 25, 2016: Microbial Pathogenesis
https://www.readbyqxmd.com/read/27893465/accelerated-resolution-of-inflammation-underlies-sex-differences-in-inflammatory-responses-in-humans
#6
Krishnaraj S Rathod, Vikas Kapil, Shanti Velmurugan, Rayomand S Khambata, Umme Siddique, Saima Khan, Sven Van Eijl, Lorna C Gee, Jascharanpreet Bansal, Kavi Pitrola, Christopher Shaw, Fulvio D'Acquisto, Romain A Colas, Federica Marelli-Berg, Jesmond Dalli, Amrita Ahluwalia
BACKGROUND: Cardiovascular disease occurs at lower incidence in premenopausal females compared with age-matched males. This variation may be linked to sex differences in inflammation. We prospectively investigated whether inflammation and components of the inflammatory response are altered in females compared with males. METHODS: We performed 2 clinical studies in healthy volunteers. In 12 men and 12 women, we assessed systemic inflammatory markers and vascular function using brachial artery flow-mediated dilation (FMD)...
November 28, 2016: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/27887604/variable-ventilation-improves-pulmonary-function-and-reduces-lung-damage-without-increasing-bacterial-translocation-in-a-rat-model-of-experimental-pneumonia
#7
Raquel F de Magalhães, Cynthia S Samary, Raquel S Santos, Milena V de Oliveira, Nazareth N Rocha, Cintia L Santos, Jamil Kitoko, Carlos A M Silva, Caroline L Hildebrandt, Cassiano F Goncalves-de-Albuquerque, Adriana R Silva, Hugo C Faria-Neto, Vanessa Martins, Vera L Capelozzi, Robert Huhle, Marcelo M Morales, Priscilla Olsen, Paolo Pelosi, Marcelo Gama de Abreu, Patricia R M Rocco, Pedro L Silva
BACKGROUND: Variable ventilation has been shown to improve pulmonary function and reduce lung damage in different models of acute respiratory distress syndrome. Nevertheless, variable ventilation has not been tested during pneumonia. Theoretically, periodic increases in tidal volume (VT) and airway pressures might worsen the impairment of alveolar barrier function usually seen in pneumonia and could increase bacterial translocation into the bloodstream. We investigated the impact of variable ventilation on lung function and histologic damage, as well as markers of lung inflammation, epithelial and endothelial cell damage, and alveolar stress, and bacterial translocation in experimental pneumonia...
November 25, 2016: Respiratory Research
https://www.readbyqxmd.com/read/27876538/neutrophil-to-lymphocyte-ratio-and-the-hematoma-volume-and-stroke-severity-in-acute-intracerebral-hemorrhage-patients
#8
Yaming Sun, Shoujiang You, Chongke Zhong, Zhichao Huang, Lifang Hu, Xia Zhang, Jijun Shi, Yongjun Cao, Chun-Feng Liu
BACKGROUND: Neutrophil to lymphocyte ratio (NLR) serves as a powerful inflammatory marker for predicting cardiovascular events. Here, we investigate whether admission NLR is associated with hematoma volume, stroke severity, and 3-month outcomes in patients with acute intracerebral hemorrhage (ICH). METHODS: 352 patients with acute ICH were prospectively identified in this study. Demographic characteristics, lifestyle risk factors, NIHSS score, hematoma volumes, and other clinical features were recorded for all participants...
November 16, 2016: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27875664/systemic-il-6-effector-response-in-mediating-systemic-bone-loss-following-inhalation-of-organic-dust
#9
Adam Wells, Debra J Romberger, Geoffrey M Thiele, Todd A Wyatt, Elizabeth Staab, Art J Heires, Lynell W Klassen, Michael J Duryee, Ted R Mikuls, Anand Dusad, William W West, Dong Wang, Jill A Poole
Airway and skeletal diseases are prominent among agriculture workers. Repetitive inhalant exposures to agriculture organic dust extract (ODE) induces bone deterioration in mice; yet the mechanisms responsible for connecting the lung-bone inflammatory axis remain unclear. We hypothesized that the interleukin (IL)-6 effector response regulates bone deterioration following inhalant ODE exposures. Using an established intranasal inhalation exposure model, wild-type (WT) and IL-6 knockout (KO) mice were treated daily with ODE or saline for 3 weeks...
November 22, 2016: Journal of Interferon & Cytokine Research
https://www.readbyqxmd.com/read/27858908/predictive-value-of-neutrophil-to-lymphocyte-ratio-in-diagnosis-of-prostate-cancer-among-men-who-underwent-template-guided-prostate-biopsy-a-strobe-compliant-study
#10
Tian-Bao Huang, Shi-Yu Mao, Sheng-Ming Lu, Jun-Jie Yu, Yang Luan, Xiao Gu, Hao Liu, Guang-Chen Zhou, Xue-Fei Ding
To evaluate the predictive value of neutrophil-to-lymphocyte ratio (NLR) in diagnosis of prostate cancer (PCa). Data of 662 patients who underwent prostate biopsy from January 2012 to June 2016 were retrospectively reviewed. The receiver operating characteristic-derived area under the curve analyses were performed to assess the predictive accuracy. Simultaneously, Youden's index was calculated to determine the optimal NLR cutoff. Furthermore, univariate and multivariate logistic regression analyses were performed to determine the association between NLR value and PCa detection...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27846467/red-blood-cell-distribution-width-predicts-homocysteine-levels-in-adult-population-without-vitamin-b12-and-folate-deficiencies
#11
You-Fan Peng, Guo-Gang Pan
OBJECTIVES: Our aim in this study was to explore the relationship between red blood cell distribution width (RDW) and homocysteine levels in an adult population. METHODS: The study included 344 subjects who underwent health check-up in our hospital. The demographic characteristics and laboratory parameters of participants were grouped in accordance with tertiles of RDW. RESULTS: An increase of homocysteine levels was found from the first to third tertiles of RDW in all participants...
November 9, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27833150/systemic-inoculation-of-escherichia-coli-causes-emergency-myelopoiesis-in-zebrafish-larval-caudal-hematopoietic-tissue
#12
Yuelan Hou, Zhen Sheng, Xiaobing Mao, Chenzheng Li, Jingying Chen, Jingjing Zhang, Honghui Huang, Hua Ruan, Lingfei Luo, Li Li
Emergency granulopoiesis occurs in response to severe microbial infection. However, whether and how other blood components, particularly monocytes/macrophages and their progenitors, including hematopoietic stem/progenitor cells (HSPCs), participate in the process and the underlying molecular mechanisms remain unknown. In this study, we challenged zebrafish larvae via direct injection of Escherichia coli into the bloodstream, which resulted in systemic inoculation with this microbe. The reaction of hematopoietic cells, including HSPCs, in the caudal hematopoietic tissue was carefully analysed...
November 11, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27823973/serum-monocyte-fraction-of-white-blood-cells-is-increased-in-patients-with-high-gleason-score-prostate-cancer
#13
Takuji Hayashi, Kazutoshi Fujita, Go Tanigawa, Atsunari Kawashima, Akira Nagahara, Takeshi Ujike, Motohide Uemura, Tetsuya Takao, Seiji Yamaguchi, Norio Nonomura
Systemic inflammation and immune responses are reported to be associated with progressive prostate cancer. In this study, we explored which among the fractions of white blood cell (WBC) and C-reactive protein (CRP) level were associated with high Gleason score prostate cancer. Prostate needle biopsy was performed in 966 men with suspicion of prostate cancer. We assessed age, serum prostate-specific antigen (PSA), prostate volume, WBC count, fractions of WBCs (neutrophils, lymphocytes, monocytes, basophils, and eosinophils), and CRP level before biopsy for associations with biopsy findings...
November 3, 2016: Oncotarget
https://www.readbyqxmd.com/read/27818230/effect-of-ppar-%C3%AE-%C3%AE-agonist-gw0742-treatment-in-the-acute-phase-response-and-blood-brain-barrier-permeability-following-brain-injury
#14
Khouloud Chehaibi, Laura le Maire, Sarah Bradoni, Joan Carles Escola, Francisco Blanco-Vaca, Mohamed Naceur Slimane
The systemic response to ischemic stroke is associated with the hepatic acute phase response (APR) that modulates leukocytes recruitment to the injured brain. The inappropriate recruitment of leukocytes to the brain parenchyma can result in blood-brain barrier (BBB) breakdown. Emerging data suggest that peroxisome proliferator-activated receptor beta/delta (PPAR-β/δ) activation has a potential neuroprotective role in ischemic stroke. However, mechanisms of PPAR-β/δ mediated protection in ischemic insults remain unclear...
October 18, 2016: Translational Research: the Journal of Laboratory and Clinical Medicine
https://www.readbyqxmd.com/read/27815259/aging-exacerbates-acute-lung-injury-induced-changes-of-the-air-blood-barrier-lung-function-and-inflammation-in-the-mouse
#15
Katharina Maria Kling, Elena Lopez-Rodriguez, Christiane Pfarrer, Christian Mühlfeld, Christina Brandenberger
Acute lung injury (ALI) is characterized by hypoxemia, enhanced permeability of the air-blood barrier and pulmonary edema. Particularly in the elderly ALI is associated with increased morbidity and mortality. The reasons for this, however, are poorly understood. We hypothesized that age-related changes in pulmonary structure, function and inflammation, lead to a worse prognosis in ALI. ALI was induced in young (2 months) and old (18 months) male C57BL/6 mice by intranasal application of 2.5 mg lipopolysaccharide (LPS)/kg body weight or saline (control mice)...
November 4, 2016: American Journal of Physiology. Lung Cellular and Molecular Physiology
https://www.readbyqxmd.com/read/27808471/neutrophil-volume-distribution-width-as-a-new-marker-in-detecting-inflammatory-bowel-disease-activation
#16
Y Aydemir, A Pınar, G Hızal, H Demir, I N Saltık Temizel, H Özen, F Akbıyık, A Yüce
INTRODUCTION: We sought to investigate the value of neutrophil volume distribution width in detecting inflammatory bowel disease activation. METHODS: Patients with infection and accompanying inflammatory disease were excluded. All the patients were diagnosed and classified according to Porto criteria and Paris classification, respectively. Physician global assessment, pediatric Crohn's disease and pediatric ulcerative colitis activity indexes and fecal calprotectin were used to define disease activation...
November 3, 2016: International Journal of Laboratory Hematology
https://www.readbyqxmd.com/read/27798158/loss-of-neurokinin-1-receptor-alters-ocular-surface-homeostasis-and-promotes-an-early-development-of-herpes-stromal-keratitis
#17
Subhash Gaddipati, Pushpa Rao, Andrew David Jerome, Bala Bharathi Burugula, Norma P Gerard, Susmit Suvas
Substance P neuropeptide and its receptor, neurokinin-1 receptor (NK1R), are reported to present on the ocular surface. In this study, mice lacking functional NK1R exhibited an excessive desquamation of apical corneal epithelial cells in association with an increased epithelial cell proliferation and increased epithelial cell density, but decreased epithelial cell size. The lack of NK1R also resulted in decreased density of corneal nerves, corneal epithelial dendritic cells (DCs), and a reduced volume of basal tears...
November 15, 2016: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/27797257/diagnostic-power-of-blood-parameters-as-screening-markers-in-gastric-cancer-patients
#18
Lukasz Pietrzyk, Zbigniew Plewa, Marta Denisow-Pietrzyk, Remigiusz Zebrowski, Kamil Torres
BACKGROUND: Gastric cancer (GC) is the fifth most common cancer worldwide. Since development is usually asymptomatic, it is generally diagnosed at an advanced stage. The value of screening in patients with nonspecific symptoms for GC is controversial. AIM: The study aimed to evaluate whether hematological parameters (platelet count (PC), mean platelet volume (MPV), MPV/PC ratio, red blood cell distribution width (RDW), neutrophil to lymphocyte ratio (NLR), and platelet to lymphocyte ratio (PLR)) are useful markers to differentiate between gastric cancer patients and healthy individuals...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27789786/non-invasive-near-infrared-fluorescence-imaging-of-the-neutrophil-response-in-a-mouse-model-of-transient-cerebral-ischaemia
#19
Markus Vaas, Gaby Enzmann, Therese Perinat, Ulrich Siler, Janine Reichenbach, Kai Licha, Anja Kipar, Markus Rudin, Britta Engelhardt, Jan Klohs
Near-infrared fluorescence (NIRF) imaging enables non-invasive monitoring of molecular and cellular processes in live animals. Here we demonstrate the suitability of NIRF imaging to investigate the neutrophil response in the brain after transient middle cerebral artery occlusion (tMCAO). We established procedures for ex vivo fluorescent labelling of neutrophils without affecting their activation status. Adoptive transfer of labelled neutrophils in C57BL/6 mice before surgery resulted in higher fluorescence intensities over the ischaemic hemisphere in tMCAO mice with NIRF imaging when compared with controls, corroborated by ex vivo detection of labelled neutrophils using fluorescence microscopy...
October 27, 2016: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/27774423/evaluation-of-in%C3%A2-vivo-antitumor-activity-of-cleistanthin-b-in-swiss-albino-mice
#20
Vipul R Thummar, Subramani Parasuraman, Debdatta Basu, Ramasamy Raveendran
To evaluate the in vivo antitumor activity of cleistanthin B in Ehrlich's ascites carcinoma (EAC) and Dalton's ascites lymphoma (DAL) cell lines induced malignant ascites mouse models and DAL cell line induced solid tumor mouse model. All animals were injected with 2 × 10(6) EAC/DAL cells i.p./s.c. to induce malignant ascites and solid tumor and treated with 5-fluorouracil (5-FU) 20 mg/kg or cleistanthin B for 10 days. Cleistanthin B was given at three doses viz. 25, 50 and 100 mg/kg. The percentage increase in life span and the overall survival in malignant ascites animals and the tumor volume in solid tumor animals were measured...
October 2016: Journal of Traditional and Complementary Medicine
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